Permeability evolutionary patterns of fractured rock masses in fault zones under seepage-stress coupling by Dekang ZHAO, Bing HAN, Yifan ZENG, Guorui FENG, Yonghong XI, Bofeng CHANG, Zhenghao LI, Pengwei WANG, Lisan WANG

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Osimertinib plus anlotinib for advanced NSCLC with acquired EGFR T790M mutation: results from a multicenter phase II study with ctDNA analysis by Xinyue Wang, Zhaona Li, Liuchun Wang, Yan Liang, Chun Huang, Peng Chen, Dingzhi Huang, Xia Song, Cuimin Ding, Changli Wang, Richeng Jiang

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Efficacy and safety of levilimab in combination with methotrexate in patients with active rheumatoid arthritis: 56-week results of phase III randomized double-blind placebo-control... by V. I. Mazurov, A. M. Lila, M. A. Korolev, A. M. Prystrom, A. V. Kundzer, N. F. Soroka, A. A. Kastanayan, T. V. Povarova, T. V. Plaksina, O. V. Antipova, D. G. Krechikova, S. A. Smakotina, O. A. Tciupa, E. V. Puntus, T. A. Raskina, L. N. Shilova, T. V. Kropotina, O. B. Nesmeyanova, T. A. Popova, I. B. Vinogradova, E. A. Dokukina, A. V. Plotnikova, P. S. Pukhtinskaia, A. V. Zinkina-Orikhan, Yu. N. Linkova, A. V. Eremeeva, A. A. Lutckii, E. L. Nasonov

“…After switching to LVL Q2W, rates of ACR70 and DAS28-CRP<2.6 did not significantly changed until W52: 17/27 (63.0%) and 21/27 (77.8%), respectively, yet the proportion of subject with ACR/EULAR 2011 remission further increased and reached 12/27 (44.4%).LVL QW arm was diminished by subjects who achieved high response to treatment at W24 and composed LVL QW/Q2W arm. …”
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Tuning the physical properties of ternary alloys (NiCuCo) for in vitro magnetic hyperthermia: experimental and theoretical investigation by O. M. Lemine, Noura Al-Dosari, Saja Algessair, Nawal Madkhali, Moustapha Elansary, Chouaïb Ahmani Ferdi, Marzook S Alshammari, Rizwan Ali, Ali Z. Alanzi, Mohammed Belaiche, Kheireddine El-Boubbou

“…Importantly, the nanoalloys reached the required temperatures for magnetic hyperthermia (42 °C) in relatively short times. …”
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Calcium oscillations in mesenchymal stem cells, a control on cell cycle progression to influence cell fate towards proliferation or differentiation? by Leslie A. Vallet, Marina Sánchez-Petidier, Romain Fernandes, Nataliia Naumova, Caterina Merla, Claudia Consales, Giorgia Innamorati, Franck M. André, Lluis M. Mir

“…Abstract Background Under regular culture conditions, mesenchymal stem cells (MSCs) exhibit cytosolic calcium concentration oscillations (Ca2+ oscillations), that change, especially in frequency, after the differentiation of the MSCs. …”
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In-person vs mobile app facilitated life skills education to improve the mental health of internally displaced persons in Nigeria: protocol for the RESETTLE-IDPs cluster randomized... by Ejemai Eboreime, Chisom Obi-Jeff, Rita Orji, Tunde M Ojo, Ihoghosa Iyamu, Bala I Harri, Jidda M Said, Funmilayo Oguntimehin, Abdulrahman Ibrahim, Omolayo Anjorin, Andem Effiong Etim Duke, Umar Baba Musami, Linda Liebenberg, Raquel Crider, Lydia Wagami, Asmau MC Dahiru, Jesse C. Uneke, Sanni Yaya, Vincent IO Agyapong

“…The study will be guided by the Reach-Effectiveness-Adoption-Implementation-Maintenance (RE-AIM) framework. …”
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Metformin treatment for patients with hand osteoarthritis: protocol for the multicentre, randomised, placebo-controlled METRO trial by David J Hunter, Robin Christensen, Marius Henriksen, Henning Bliddal, Karen Ellegaard, Mikael Boesen, Tue Kragstrup, Filip K Knop, Anna Dossing, Kasper Staberg Madsen, Asbjørn S Poulsen, Rasmus Oscar

“…The primary endpoint is the between-group difference in least squares means for the change in the Visual Analogue Scale (VAS) finger joint pain scores between the metformin and placebo groups at 16 weeks. …”
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Integrative transcriptome and WGCNA analysis reveal key genes mainly in response to Alternaria alternata in Populus simonii × P. nigra by Siyuan Liu, Siyuan Liu, Siyuan Liu, Lijuan Dai, Guanzheng Qu, Xinming Lu, Hong Pan, Xiaoyu Fu, Airong Dong, Airong Dong, Libin Yang

“…The contents of SA and JA, as well as the enzymatic activities of SOD, PAL, and POD, reached their maxima on the third day before exhibiting a downward tendency. …”
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Platelets as a potential new immune coordinator in T cell-mediated aplastic anemia by Shuai Tan, Huizhen He, Yuxin Li, Mingyue Shang, Yaofang Cao, Dongmei Zou, Ronghua Hu, Wuhan Hui, Xiaoli Chang, Jing Ni, Qiang Ma, Li Su, Jing Sun, Wanxue He, Xingmin Feng, Wanling Sun

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Genomic and machine learning approaches to predict antimicrobial resistance in Stenotrophomonas maltophilia by Xin Liu, Shanshan Long, Fangyuan Chen, Chang Liu, Peng Han, Hua Yu, Xiaobo Huang, Chun Pan, Ruiming Yue, Wentao Feng, Guanhua Rao, Han Shen, Lingai Pan

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Using Implementation Science to Evaluate the Implementation of Patient-Reported Outcome Measures (PROMs) in a Clinical Heart Failure Care Setting by Sarah V.C. Lawrason, MSc, PhD, Heather Ross, MSc, MD, Michael McDonald, MD, Juan Duero Posada, MD, Samantha Engbers, BAH, Anne Simard, MHSc

“…Méthodologie: Le cadre RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) a servi de guide à ce projet d’amélioration de la qualité sur une période d’un an avec des méthodes mixtes. …”
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Mechanisms and Strength Characteristics of Bio-based Solidified Lightweight Red Sandstone Residual Soil by WEN Shu-jie, XU Chang-yi, HUANG Xiang, HUANG Ying-hao, FU He-lin

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Effects of Bojungikki-Tang on immune response and clinical outcomes in NSCLC patients receiving immune checkpoint inhibitors: a randomized pilot study by Mi Mi Ko, Se Won Na, Jin-Mu Yi, Ho Jang, Chang Min Choi, Seung Hyeun Lee, Sung Yong Lee, Mi-Kyung Jeong

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Effect of two-dimensional functional fillers size on the performance of BN/EPDM flexible neutron protection composite materials by ZONG Bo, ZENG Deyang, WANG Kaikai, TANG Wencai, FU Jiajia, CHANG Shuquan, HE Jialin, CHEN Fanglei, LI Ziping, LI Da

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Assessing SWOT interferometric SAR altimetry for inland water monitoring: insights from Lake Léman by Henri Bazzi, Nicolas Baghdadi, Yen-Nhi Ngo, Cassandra Normandin, Frédéric Frappart, Cecile Cazals

“…Monitoring water levels is crucial for managing water resources and addressing climate change challenges. The new Surface Water and Ocean Topography (SWOT) mission provides unprecedented spatial and temporal resolution estimates of water surface elevations (WSEs) globally. …”
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The Impact of Mixed Application of Modified Straw Biochar and Organic Fertilizer on Soil Water Retention and Fertility Maintenance in the Loess Hilly Dry Area by ZHANG Peizhen, LUO Juan, YAO Zonglu, CHANG Fangling, HUO Lili, ZHAO Lixin

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Study of clinical effect of original and generic amlodipines in arterial hypertension with obesity: results of randomized cross-over study by M. G. Bubnova, I. V. Kuznetsova, D. M. Aronov, V. A. Vygodin, V. B. Krasnitsky

“…Beginning dose was 5 mg and in 2 weeks increased to 10 mg daily if target BP was not reached  (<140/90 mmHg). After finishing treatment period by the first drug, there was 2-week washout and then the same therapy period but with another drug. …”
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Low ITN utilization among households in SWEPR Ethiopia: challenge for malaria elimination, a mixed design approach by Wondwossen Niguse, Bezuayehu Alemayehu, Tadesse Gebremedhin, Mathewos Alemu, Girma Mamo, Ephrem Negeri, Ibrahim Temam, Haile Zewdie, Tamirat Bogale, Erkyihun pawulos, Endale Sahlie

“…Firstly, the malaria area was selected purposively and the study participants were reached by using multi-stage stratified sampling techniques. …”
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Effect of probiotic “Subalin” on the productive parameters of age-0+ sturgeon hybrid (Acipenseridae) — bester under conditions of thermal load by Yu. Onyshchuk, O. Tretiak, O. Kolos

“…The obtained results are of interest for the development of sturgeon aquaculture in industrial-type farms, in particular at elevated water temperatures in conditions of climate change.…”
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Toward a sustained recovery of the lodging sector: a management path to lessen the Corona Variants upshots by Ola Abdel Moneim Emara, Hazem Tawfik Halim, Mohamed Samy El-Deeb, Yasser Tawfik Halim

“…This configures an input, transform (actions), output, outcome, and impact result chain. The study reaches the findings that sustainable recovery in the lodging sector—being sensitive to the uncertainty that the Virus “Variants” create—necessitates the merge between managing the emergency, adopting pliable approaches, alongside with the enhancement of the managers’ (hoteliers) role as a supporting premise.…”
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