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    Effect of Motivational Enhancement Therapy on Patterns of Substance Abuse in Postpartum Women: A Randomized Clinical Trial by Fatemeh Esmaeilinejad Hasaroeih, Nasim Shahrahmani, Atefeh Ahmadi, Moghaddameh Mirzaee, Katayoun Alidousti, Morteza Hashemian

    Published 2022-06-01
    “…Materials and Methods: This clinical trial was conducted on 60 eligible postpartum women with SUD (30 in the intervention group and 30 control), who were selected using a random sampling method from the postpartum unit of a hospital in Kerman, Iran in 2019. …”
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    Effect of drama-education for alcohol/substance user on attitudes toward violence against women: randomized controlled design by Hümeyra Hançer Tok, Makbule Tokur Kesgin

    Published 2025-05-01
    “…Methods This study has a pre-test post-test parallel group randomized controlled design. …”
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    Protocol for a randomized controlled trial of patient–portal–based screening for substance use among people with HIV by Eric Roessler, Daniela Zimmer, Jon Grant, Harold Pollack, Basmattee Boodram, Jessica Schmitt, Jessica Schmitt, Eleanor Friedman, Jade Pagkas-Bather, Jade Pagkas-Bather, Russell A. Brewer, Jessica Ridgway, Neda Laiteerapong, Neda Laiteerapong

    Published 2025-08-01
    “…This will lay the groundwork for the second aim, the focus of the current manuscript, RCT to measure the effectiveness of a population health, patient portal-based substance use screening program. Approximately 880 people will be enrolled and randomized 1:1 to intervention vs., control arms. …”
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    Influence of Spiritual Support Program on Quality‐of‐Life of Stroke Survivors Post Substance Overdose: A Randomized Controlled Trial by Leyla Alilu, Mansour Arad, Rasoul Goli, Amireh Hassanpour, Navid Faraji, Sorena Nazarbaghi

    Published 2025-05-01
    “…This study aimed to evaluate the influence of a spiritual support program on the quality of life of this patient population. Methods A randomized controlled trial was conducted in the ICU ward of Imam Khomeini Hospital in Iran with stroke survivors who had experienced substance overdose. …”
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    Current state of mental health and substance use in Toledo, Belize: A mixed methods study by Jaclyn Kirsch, Megan Fabbri, Kristen Kerr, Lynette Gomez

    Published 2025-01-01
    “…Using community-based participatory research methods, this preliminary mixed methods study (quantitative n = 163; qualitative n = 10) aims to (1) investigate mental health symptoms and substance use patterns in a non-randomized sample of individuals from southern Belize and (2) explore community perspectives on mental health among community stakeholders. …”
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    Potential predictors affecting outcomes in a randomized controlled trial of support programs for parents of young adults with hazardous substance use by Ola Siljeholm, Anders Hammarberg

    Published 2025-07-01
    “…Outcomes were assessed at 24-weeks following a randomized controlled trial (RCT) comparing Community Reinforcement and Family Training (CRAFT) and manualized counselling for parents of young adults (18-24 years) with hazardous substance use. …”
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    Investigating the causal role of serum metabolites in substance use disorder risk: a study integrating Mendelian randomization and synthesis analysis by WeiXiong Xu, DanDan Xie, ZhenZhu Zhang, PiBo Du, YongJian Ye, XuBo Dai

    Published 2025-08-01
    “…Abstract Objective This study aimed to explore how serum metabolites affect the risk of substance use disorders (SUD). Methods In the initial stage, Mendelian randomization was applied to assess the relationship between 1,400 serum metabolites and SUD. …”
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    The power of lived experience in optimizing US policymakers’ engagement with substance use research: A series of rapid-cycle randomized controlled trials by Elizabeth C. Long, Riley Loria, Jessica Pugel, Patrick O’Neill, Camille C. Cioffi, Charleen Hsuan, Glenn Sterner, D. Max Crowley, J. Taylor Scott

    Published 2024-12-01
    “…This study tested the use of narratives to boost policymakers’ research engagement. Methods: In five rapid-cycle randomized controlled trials, SU/SUD research fact sheets were emailed to US legislative policymakers. …”
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    Repeated prefrontal tDCS improves cognitive emotion regulation and readiness for treatment in substance use disorder: A randomized sham-controlled study by Ali Salmani, Sajjad Basharpoor, Zahra Vaziri, Mohammad Ali Salehinejad

    Published 2025-06-01
    “…Methods: Thirty-two young male iSUDs (mean age= 22.80±1.92) were randomly assigned to the experimental (n=16) or placebo (n=16) groups. …”
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    Does smoking cessation reduce other substance use, psychiatric symptoms, and pain symptoms? Results from an emulated hypothetical randomized trial of US veterans. by Kaoon Francois Ban, Erin Rogers, Maria Khan, Joy Scheidell, Dyanna Charles, Kendall J Bryant, Amy C Justice, R Scott Braithwaite, Ellen C Caniglia

    Published 2024-01-01
    “…However, causal inferences regarding smoking cessation and its subsequent benefits have been limited.<h4>Methods</h4>We emulated a hypothetical open-label randomized control trial of smoking cessation using longitudinal observational data of HIV-positive and HIV-negative US veterans from 2003-2015 in the Veterans Aging Cohort Study. …”
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    Elucidating the associations and molecular mechanisms of perfluoroalkyl substances exposure with type 2 diabetes and its complications: A multifaceted approach by Xinghai Liu, Xin Wang, Li Wang

    Published 2025-09-01
    “…This study aims to investigate the relationships between PFASs exposure and the onset of T2D and its complications, and to elucidate the underlying molecular mechanisms. Methods: Mendelian randomization (MR) analysis was conducted to evaluate the relationships between PFASs exposure and the onset of T2D and its complications. …”
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    Intervention for Justice-Involved Homeless Veterans With Co-Occurring Substance Use and Mental Health Disorders: Protocol for a Randomized Controlled Hybrid Effectiveness-Implement... by Kathryn Bruzios, Paige M Shaffer, Daniel M Blonigen, Michael A Cucciare, Michael Andre, Thomas Byrne, Jennifer Smith, David Smelson

    Published 2025-07-01
    “…ObjectiveWe aimed to (1.1) evaluate whether the Maintaining Independence and Sobriety through Systems Integration, Outreach, and Networking Criminal Justice version (MISSION-CJ) intervention lowers criminal recidivism and improves health-related outcomes; (1.2) examine the mechanisms that impact outcomes; and (2) qualitatively assess the implementation of MISSION-CJ. MethodsVeterans participating in an MH RRTP (N=226) will be randomized to the enhanced usual care (EUC) or MISSION-CJ conditions in a hybrid type 1 randomized controlled trial to test the effectiveness and implementation of MISSION-CJ, a multicomponent intervention for co-occurring disorder. …”
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    Smoking cessation treatment prior to psychotherapy for patients with diagnosed mental disorders: study protocol for a randomized controlled trial by Esra Teresa Sünkel, Marie Neubert, Alla Machulska, Tim Klucken

    Published 2025-07-01
    “…By aligning tobacco dependence treatment with approaches used for other substance use disorders, we aim to establish and discuss a comprehensive and guideline-conformant method. …”
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