Topical olive oil is not inferior to hyperoxygenated fatty aids to prevent pressure ulcers in high-risk immobilised patients in home care. Results of a multicentre randomised tripl... by Inmaculada Lupiañez-Perez, Shakira Kaknani Uttumchandani, Juan Carlos Morilla-Herrera, Francisco Javier Martin-Santos, Magdalena Cuevas Fernandez-Gallego, Francisco Javier Navarro-Moya, Yolanda Lupiañez-Perez, Eugenio Contreras-Fernandez, Jose Miguel Morales-Asencio

“…Most of studies to prevent pressure ulcers have been carried out in hospital contexts, with respect to the use of hyperoxygenated fatty acids and to date, no studies have specifically examined the use of olive oil-based substances.<h4>Methods and design</h4>Main objective: To assess the effectiveness of the use of olive oil, comparing it with hyperoxygenated fatty acids, for immobilised home-care patients at risk of suffering pressure ulcers. …”
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Colour Stability and Lipid Oxidation of Beef Longissimus Lumborum under Different Packaging Conditions by Bonny Dadji Stéphane Serge, Li Xin, Li Zheng, Li Meng, Du Manting, Gao Lingling, Zhang Dequan

“…The objective of this study was to investigate the colour stability and lipid oxidation of beef under different packaging methods. The muscles longissimus lumborum were randomly packed in vacuum or modified atmosphere packaging (MAP, 80% O2, 20% CO2). …”
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The role of adipose tissue cell elements in the regulation of the nitroxidergic system and possible ways of pharmacological modulation by I. F. Bielenichev, S. O. Maslennikov, N. V. Dobrelia, O. S. Khromov, M. L. Holovakha, V. P. Ryzhenko, O. O. Brek

“…The aim: to evaluate the role of adipose tissue elements in the regulation of parameters of the nitroxidergic system under hypoxia conditions. Materials and methods. The studies were carried out on 30 adult white male Wistar rats. …”
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COMPARATIVE STUDY OF COMBINED DRUGS OF ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE: «RENIPRIL HT» AND «CO-RENITEC» IN PATIENTS WITH MILD TO MODERATE ARTERIAL HYPERTENSION by S. Y. Martsevich, J. V. Lukina, A. D. Deev, N. S. Oganisyan, N. A. Dmitrieva, N. Y. Ivanenkova, A. A. Serazhim, V. P. Voronina, M. P. Kozireva

“…Tto study efficiency and safety of new combined drug of enalapril maleate and hydrochlorothiazide “Renipril HT: in patients with mild to moderate arterial hypertension (AH) in comparison with the original combined drug with the same substances – “Co-renitec”, possibility of reaching target blood pressure (BP) level with separate treatment with each drug, and in combination with atenolol if necessary.Material and methods. 30 patients (11 men and 19 women) with mild to moderate AH took part in randomized, open, cross over study. 10-14 days before the study started, previous antihypertensive treatment had been canceled for all the patients. …”
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Effect of extracted phycocyanin by-products as a synbiotic supplement on the production performance and intestinal morphology of broilers by Kannikar Hamprakorn, Buaream Maneewan, Wantamas Jantasin, Mohd Nizam Lani, Tossapol Moonmanee, Julakorn Panatuk

“…This study aimed to evaluate the effect of by-products acquired during phycocyanin extraction, which is used as a novel synbiotic supplement, on the production performance and intestinal health of broilers in a tropical climate. Materials and Methods: A total of 240 one-day-old male Ross 308 broilers were randomly distributed among five dietary treatment groups; they received a diet supplemented with a synbiotic product (probiotic [Lactobacillus johnsonii] at least 1.0 × 108 colony-forming unit/mg with prebiotic [by-product of phycocyanin extraction]) at 0.000%, 0.025%, 0.050%, 0.075%, and 0.100%. …”
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The Impact of High Intensity Interval Training and Bee Pollen Supplementation on BDNF Levels in Rats Exposed to Cadmium by Sam Rahmani Chegani, Mehdi Rozbahani, Seyed Ali Hosseini, Ahmad Hematfar, Masoud Moini

“…The present study aimed to investigate the effectiveness of HIIT and bee pollen on brain-derived neurotrophic factor (BDNF) levels in rats exposed to cadmium. Materials and methods: In this experimental study, 25 Sprague-Dawley male rats, 8 weeks old with an average weight of  258 g, were randomly divided into five groups of five: (1) healthy control (HC), (2) cadmium (CD), (3) cadmium + bee pollen (PO), (4) cadmium + training (HIIT) and (5) cadmium + bee pollen + training (HIIT-PO). …”
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Protective Effects of Konjac and Inulin Extracts on Type 1 and Type 2 Diabetes by Tianle Gao, Yue Jiao, Yang Liu, Tao Li, Zhiguo Wang, Danqiao Wang

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Yangke powder alleviates OVA-induced allergic asthma by inhibiting the PI3K/AKT/NF-κB signaling pathway by Xueyan Li, Lu Ding, Zirui Li, Zhenghua Cao, Min Li, Kai Yin, Siyu Song, Liyuan Cao, Qinjing Xia, Zihan Wang, Daqing Zhao, Xiaolin Tong, Xiangyan Li, Zeyu Wang

“…Objective This study aims to identify the key active ingredients in YKS and explore their mechanisms, particularly through the PI3K/AKT/NF-κB pathways, to provide a scientific basis for its application in asthma treatment. Methods We employed UPLC-Q-Exactive Orbitrap-MS to analyze YKS constituents, identified key ingredients, and explored asthma treatment mechanisms through bioinformatics, network pharmacology, Mendelian randomization, and molecular docking. …”
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Comparative Analysis of Biochemical Parameters, Thermal Behavior, Rheological Features, and Gelling Characteristics of Thai Ligor Hybrid Chicken and Broiler Meats by Ngassa Julius Mussa, Chantira Wongnen, Warangkana Kitpipit, Worawan Panpipat, Mingyu Yin, Siriporn Riebroy Kim, Manat Chaijan

“…The composite meat samples, which comprise minced breast and thigh without skin from 20 chicken carcasses in a 1:1 (<i>w</i>/<i>w</i>) ratio, were randomly selected for analysis using the completely randomized design (CRD). …”
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Efficacy of repetitive transcranial magnetic stimulation for smoking cessation: a systematic review and meta-analysis by Youssef A. Ismail, Omar K. Habib, Yahya El-Banan, Raneem Ramadan, Mohamed O. Henidak, Mohamed E. El-Badry, Ahmed R. Rabea, Amira A. Fouad, Salsapeel I. El-Tahlawy, Rahma M. El-Shawa, Mohamed Atef, Rahma A. Abd El-Kader, Abdullah El-Lawendy, Mariam El-Morsy, Mariam S. El-Rayes, Hanem El-Hasanen, Moaz Abouelmagd

“…Abstract Background Tobacco use disorder remains one of the most prevalent substances use disorders globally, contributing significantly to morbidity and mortality. …”
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Evaluation of the Efficiency of a Soft Dosage Form for the Treatment of Osteoarthritis: Influence on the Level of Pro-inflammatory Cytokines by U. V. Nogaeva, V. E. Kovanskov, D. Yu. Ivkin, E. V. Flisyuk, K. D. Yakimov, E. I. Yeletskaya, E. D. Semivelichenko, V. G. Antonov

“…Evaluation of the effect of a previously developed soft dosage form containing meloxicam, a purine derivative and an immunomodulator M on the level of pro-inflammatory cytokines: IL-1α, IL-1β, IL-6 and TNF-α in osteoarthritis.Materials and methods. The experiment included 25 animals, which were divided into 5 groups by simple randomization: 1 – test (gel 0.5 %), 2 –test (gel 1 %), 3 – reference (Amelotex®, gel 1 %), 4 – control (gel base); 5 – intact. …”
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Study on the Mechanism of Curcumin Regulating Lung Injury Induced by Outdoor Fine Particulate Matter (PM2.5) by Kunlun Huang, ChanMei Shi, JingQi Min, Laifu Li, Tao Zhu, Huapeng Yu, Huojin Deng

“…To investigate whether curcumin can play a protective role against PM2.5-induced oxidative stress and inflammatory damage by inducing expression of the HO-1/CO/P38 MAPK pathway. Methods. In this experiment, PM2.5 was dropped into the trachea to establish a lung injury model in mice. 28 SPF-grade male Kunming mice were randomly divided into 4 groups: normal control group, saline control group, PM2.5 treatment group, and curcumin intervention group. …”
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Combination of Essential Oils and Extracts Enriched with Tocopherols in Diet of Holstein Steers and Its Effect on Ruminal Fermentation, Antioxidant and Anti-Inflammatory Response,... by João Gustavo Weschenfelder Wandscheer, Natalia Turcatto, Guilherme Luiz Deolindo, Mateus Henrique Signor, Alexandro Fritzen, Marcelo Vedovatto, Camila Ten Kathen Jung, Gilberto Vilmar Kozloski, Ana Carolina Hadlich Xavier, Roger Wagner, Bianca Fagan Bissacotti, Priscila Marquezan Copetti, Aleksandro Schafer da Silva

“…Background: This experiment evaluated whether the combination of essential oils (thyme, rosemary, orange) with extracts of <i>Cinnamomum</i> and <i>Quillaja saponaria</i> (enriched with tocopherols) in steers’ diet has positive effects on the health, digestibility, growth, oxidative stress, and fatty acid profile of meat. Methods: The experiment included 24 Holstein steers, divided into two groups, randomly divided (treated = phytogenic mixture (n = 12); control = monensin (n = 12)), undergoing a growth phase of 120 days and 90 days of finishing in individual pens, with a monthly collection of blood, rumen fluid, feces, and feed. …”
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The Сontent of Some Humoral and Metabolic Vasoactive Factors in the Blood of the Cirrhotic Patients and Their Dependence on the Hepatopulmonary Syndrome Severity Degree by Abrahamovych M., Tolopko S., Fayura O.

“…The aim of our study was to determine the content of some humoral and metabolic vasoactive factors, namely the endothelium-dependent (cyclic guanosine monophosphate, endothelin-1, tumor necrosis factor α), indices of the renin-aldosterone system (renin, aldosterone), natriuretic hormone in the blood of the cirrhotic patients and determine their dependence on the hepatopulmonary syndrome severity degree. Materials and methods. Into the study there were involved 80 patients [23 women (28.75 %) and 57 men (71.25 %) aged 27 to 67 years old] with LC, in a randomized manner with preliminary stratifi cation by the presence of HPS to achieve the aim. …”
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Effects of autolytical fish protein hydrolysate on growth performance, survival rate, and hematological indices in farmed juvenile beluga, Huso huso by Ali Hosseinpour Zelaty

“…This study investigates the effects of different levels of autolytical FHP on the growth performance, survival, and some blood parameters of juvenile beluga, Huso huso over a 48-day period. Materials and methods: A total of 750 belugas with an initial weight of 3 ± 0.5 g were randomly distributed into five experimental groups: a control group (without FHP), three treatments with different levels of FHP replacing fishmeal (T1, T2, and T3 with inclusion level of 2.75%, 5.5%, and 8.25%, respectively), and a positive control group (commercial feed, T4). …”
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Nano-encapsulation of Red Beetroot Extract Based on Betalain Using of Complex Coacervation in Gummy Candies by Atfeh Ghorchi, Akram Arianfar, Vahid Hakimzadeh, Sara Naji-Tabasi

“…However, all polyelectrolytes do not exhibit this phenomenon.Materials and MethodsThe features of water activity, moisture, acidity, Brix, antioxidant activity, texture characteristics, colorimetry and sensory evaluation of pastilles were investigated. …”
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The Effect of Different Levels of Galangal (Alpinia officinarum) Powder on Growth Performance, Lipid Parameters, and Liver and Aantioxidant Enzymes in Japanese Quails under Heat St... by Maryam Mahmoodinejad, Bahram Shohreh, Zarbakht Ansari Pirsaraei, Sohail Yousefi

“…This research was conducted to study the effect of different levels of Alpinia officinarum powder on growth performance, lipid profiles, and liver and antioxidant enzymes in Japanese quails under heat stress conditions. Methods: The experiment was conducted using 408 one-day-old quail chicks in the form of a completely randomized design with 17 experimental units with six treatments and four replications. …”
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The Effect of Different Lysophospholipid Levels on Blood and Milk Biochemical Parameters, Liver and Rumen Enzymes, and Rumen Microbial Population in Early Lactation of Holstein Dai... by Matin Movagharnezhad, Yadollah Chashnidel, Asadollah Teymouri Yansari, Mohsen Gholizadeh

“…In this research, the effects of using this emulsifier on blood and milk biochemical parameters, liver enzymes, and rumen microbial population are studied in the early lactation period of Holstein dairy cows. Methods: This experiment was carried out on 15 multi-calving Holstein dairy cows (three groups of five cows) with an average weight of 720 ± 50 kg and lactation days of 16 ± 5 days in a completely randomized design. …”
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The effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cows by Mónica Madrigal-Valverde, Marcus Vínicius Galvão Loiola, José Esler Freitas Junior, Murilo Ramos Santiago, Lara Lôbo Dantas, Artur Azevedo Menezes, Sandro Percário, Everton Luiz Pompeu Varela, Eduardo Costa, Endrigo Adonis Braga de Araujo, Rodrigo Freitas Bittencourt

“…This study aimed to evaluate the effects of microencapsulated hot chili pepper (MCP) supplementation on blood metabolites, antioxidant capacity, and physiological parameters in crossbred dairy cows, contributing novel insights into metabolic and physiological adaptations under tropical production systems. Materials and Methods: Twenty-four crossbred lactating cows (Bos taurus × Bos indicus); average body weight 447.8 ± 89.6 kg; 53.54 ± 11.8 days in milk; average daily milk production 6.34 ± 1.91 L/cow/day) were randomly divided into two groups: A control group without additives and a treatment group supplemented with MCP (1,000 mg/cow/day) for 42 days. …”
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24-Epibrasinolid and Cauliflower (Brassica oleracea var. botrytis) Extract Effect on Grain Yield and Some Morphophysiologycal Characteristics of the Sensitive and Tolerant Quinoa (... by R Sohrabi, A Pirzad, M Niazkhani, T MirMahmoodi

“…For this reason, the introduction of planting pattern of new plants with high yield potential, which have good agricultural performance in dry and salty conditions, and the production product, is of high quality is on the agenda. Materials and Methods In order to investigate the effect of 24-epibrassinolide and cauliflower (Brassica oleracea var. botrytis) extract on some biochemical characteristics and related to the forage quality of Quinoa cultivars at salinity levels, a factorial experiment in the form of a completely randomized design (CRD) with four replications in the greenhouse of the Faculty of Agriculture of Azad University of Mahabad in the spring and summer of the year 1401 was done. …”
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