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5041
Neuropsychological outcome of indoor rehabilitation in post-COVID-19 condition—results of the PoCoRe study
Published 2025-01-01“…Various measures were employed, including the fatigue scale for motor functioning and cognition (FSMC), the Test Battery for Attention (TAP) and the Montreal Cognitive Assessment (MoCA).ResultsOut of the 1,086 recruited participants, a total of N = 701 participants were included in the main data analysis. …”
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5042
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1
Published 2025-04-01“…Additionally, we examined the effect of PYK2 on endometriosis cells in vitro and whether VS-6063 inhibits the biological functions of endometriosis cells. Endometriosis models were established in 20 five-week-old female C57BL/6 mice, randomly allocated into experimental (n = 10) and control (n = 10) groups. …”
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5043
Effectiveness of a brief behavioural intervention on psychological distress among women with a history of gender-based violence in urban Kenya: A randomised clinical trial.
Published 2017-08-01“…<h4>Methods and findings</h4>In this single-blind, parallel, randomised controlled trial, adult women who had experienced GBV were identified through community screening for psychological distress and impaired functioning in Nairobi, Kenya. Participants were randomly allocated in a 1:1 ratio either to PM+ delivered in the community by lay community health workers provided with 8 days of training or to facility-based enhanced usual care (EUC) provided by community nurses. …”
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5044
Interventions to improve mental health and well-being in care-experienced children and young people aged less than 25: the CHIMES systematic review
Published 2024-12-01“…Interventions were primarily evaluated in the United States and targeted young people’s competencies or carers’ parenting practices. Meta-analysis reported limited evidence that interventions effectively improved mental health in the shorter term (0–6 months): total social, emotional and behavioural problems (d = −0.15, 95% confidence interval −0.28 to −0.02); internalising problem behaviours (d = −0.35, 95% confidence interval −0.61 to −0.08); externalising problem behaviours (d = −0.30, 95% confidence interval −0.53 to −0.08); depression and anxiety (d = −0.26, 95% confidence interval −0.40 to −0.13) and social–emotional functioning difficulties (d = −0.18, 95% confidence interval −0.31 to −0.05), but these impacts were not observed in the longer term (> 6 months). …”
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5045
Efficacy of Ixekizumab in Chinese Patients with Radiographic Axial Spondyloarthritis by Baseline C-Reactive Protein Level
Published 2025-05-01“…Methods This was a subgroup analysis of a Chinese phase 3 study. Adults with r-axSpA who were biologic-naïve, or tumor necrosis factor inhibitor-experienced with baseline CRP > 5 mg/l, were randomized (1:1) to receive ixekizumab 80 mg every 4 weeks (IXEQ4W) or placebo, for 16 weeks. …”
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5046
Targeting iNAMPT and NAD Biosynthesis to Break the Obesity-Associated Liver Cancer Link
Published 2025-06-01“…Protein analysis of pAkt and pErk was performed via immunoblot. …”
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5047
Absolute Configuration and Chiroptical Properties of Flexible Drug Avapritinib
Published 2025-06-01“…Enantiomeric separation was achieved via chiral liquid chromatography, followed by comprehensive chiroptical characterization including electronic circular dichroism (ECD), specific optical rotation and optical rotatory dispersion. Conformational analysis and density functional theory (DFT) calculations correlated experimental spectra with theoretical predictions, facilitating definitive configurational assignment. …”
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5048
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5049
Treating nightmares in post-traumatic stress disorder with the α-adrenergic agents clonidine and doxazosin: protocol for a phase II randomised, double-blind, placebo-controlled par...
Published 2025-08-01“…A total of 189 eligible patients will be randomly assigned to receive clonidine, doxazosin or placebo, with a once-daily oral dose administered at bedtime for 10 weeks. …”
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5050
Effects of dietary mangosteen peel powder and extract on the growth performance, meat quality and indicators for immunity, gut health and antioxidant activity in broiler chicks
Published 2024-12-01“…A total of 480 day-old straight-run broiler chicks (Ross 308) were randomly placed into four treatments, with eight replicates of 12 chicks each, and subjected to one of the four experimental diets for 21 days. …”
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5051
Evaluating the Integration of Technology by Teachers in E-Education in Elementary Schools Based on the International Standards for Technology in Education (ISTE)
Published 2024-03-01“…The study population consisted of all male elementary school teachers in district one of Hamedan city during the 2022-2023 academic year, from whom 140 people were randomly selected. Data collection was done using a researcher-made questionnaire based on the six dimensions of the ISTE (2007) standards. …”
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5052
Effects of Yeast β-Glucan Supplementation on Calf Intestinal and Respiratory Health
Published 2025-03-01“…The physiological functions of newborn calves are undeveloped, especially the immune system, making them susceptible to infections. …”
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5053
Analysing the Effects of Longwave Diathermy on Quality of Life among Patients with Knee Osteoarthritis: A Pilot Study
Published 2025-03-01“…Longwave Diathermy (LWD), known for its ability to improve circulation, reduce pain and enhance functional recovery, has emerged as a promising physiotherapeutic intervention. …”
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5054
Effects of High-Concentrate Diets on Growth Performance, Serum Biochemical Indexes, and Rumen Microbiota in House-Fed Yaks
Published 2024-12-01“…In conclusion, high-concentrate diets can enhance growth performance and alter the compositions and functions of ruminal bacterial communities in yaks.…”
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5055
Short-term use of ceftriaxone sodium leads to intestinal barrier disruption and ultrastructural changes of kidney in SD rats
Published 2023-12-01“…The aim of this study was to evaluate and visualize the impact of antibiotics on colonic mucus and the microbial community, and to assess whether intestinal dysbacteriosis is involved in the pathogenesis and progression of extraintestinal diseases in vivo.Materials and Methods Twenty-one SD rats were randomly assigned into three groups followed by different experimental treatments. …”
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5056
Dose-dependent effects of capsaicin on intestinal morphology and microbiota composition in mice: Structural, immunohistochemical, and microbial insights
Published 2025-06-01“…While low-dose administration supports mucosal integrity and promotes beneficial microbial functions, higher doses disrupt epithelial architecture and induce dysbiosis. …”
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5057
Cholesteryl Ester Species but Not Serum Proprotein Convertase Subtilisin/Kexin Type 9 Levels Decline in Male Patients with Active Inflammatory Bowel Disease
Published 2025-03-01“…In addition, FC and 15 CE species levels of 53 randomly selected IBD patients and 16 controls were determined by direct flow injection analysis (FIA) using a high-resolution hybrid quadrupole-orbitrap mass spectrometer (FIA-FTMS). …”
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5058
Predictors of Early Death in Patients With Wild‐Type Transthyretin Cardiac Amyloidosis
Published 2025-01-01“…Eighteen‐month death was predicted by NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide; cutoff 4200 ng/L), cardiac troponin I (cutoff 92 ng/L), and age (cutoff 80 years). At multivariable analysis, Eastern Cooperative Oncology Group–Performance Status >1 along with the selected variables were independent prognostic determinants and outperformed New York Heart Association functional class. …”
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5059
Single-Cell RNA Transcriptomics and Multi-omics Analyses Reveal the Clinical Effects of Acupuncture on Methadone Reduction
Published 2025-01-01“…Our findings revealed that acupuncture may activate the defense response to viruses, with altered immune cell functions in classical monocytes correlating with clinical responses to reduced methadone doses. …”
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5060
Impaired central sensitivity to thyroid hormone is associated with hypertriglyceridemia in euthyroid population
Published 2025-07-01“…BackgroundWe aimed to investigate the correlation between central thyroid hormone sensitivity and Hypertriglyceridemia (HTG) in euthyroid population.MethodsA total of 833 individuals who underwent physical examinations were randomly selected. Biochemical parameters including thyroid hormones (THs), liver and kidney functions, blood glucose, and blood lipids were measured. …”
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