Treatment with PCSK9 inhibitors influences microRNAs expression and changes of arterial wall properties: a randomized controlled trial by Andreja Rehberger Likozar, Tina Levstek, Tina Karun, Katarina Trebušak Podkrajšek, Janja Zupan, Miran Šebeštjen

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Effects of resistance exercise on patients with post-stroke dysphagia based on ACSM recommendations: a systematic review of randomized controlled trials by Yu Ye, Kairui Wu, Yingquan Liu, Hongjie Ji, Hongtao Li, Bo Jiang, Fangyuan Xu, Xuejun Li, Peijia Hu, Hongliang Cheng

“…Subgroup analyses employed random-effects meta-analyses.ResultsAnalysis included 19 RCTs (n = 566). …”
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An efficient method for predicting temperature field of PC beams with CSWs using thermocouple numerical analysis and random forest algorithm by Haiping Zhang, Hao Long, Fanghuai Chen, Yuan Luo, Xinhui Xiao, Yang Deng, Naiwei Lu, Yang Liu

“…Finally, the SHapley Additive exPlanations (SHAP)function was used to interpret the trained random forest model, and the effects of girder height, bridge orientation, solar radiation, air temperature, and ground reflectivity on the vertical temperature gradient were investigated.…”
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Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and serum thyroid function measures: Recent Findings from NHANES 2007–201... by Mo-Yao Tan, Ping Zhang, Shan Wu, Si-Xuan Zhu, Ming Gao

“…This suggests that NHHR may reflect changes in thyroid function, highlighting its potential clinical significance in assessing thyroid function and metabolic health.…”
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Limited efficacy of cold and heat therapy as adjunctive treatments for local and functional outcomes of Bothrops atrox snakebite envenomation: A randomized clinical trial. by Mailma Costa de Almeida, Kathleen Maclenny Pereira Carvalho, Yasmim da Silva Mendes, Debora Nery Oliveira, Érica da Silva Carvalho, Marco Aurélio Sartim, Felipe Queiroz Araújo, André Sachett, João Ricardo Nickenig Vissoci, Fernando Almeida-Val, Daniel Barros de Castro, Wuelton Monteiro, Jacqueline de Almeida Gonçalves Sachett

“…<h4>Methods</h4>This randomized, three-arm clinical trial included 94 patients allocated in a 1:1:1 ratio to Cold Therapy Group (CTG, n = 30), Heat Therapy Group (HTG, n = 31), or Control Group (CG, n = 33). …”
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Effect of Oscillatory Positive Expiratory Pressure in Sputum Retention, Pulmonary Function, and Thoracic Expansion in Open Abdominal Surgery -A Randomized Controlled Trial by Sudarshan Chaugale, Varun Naik, Aishwarya Gaonkar

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Efficacy of a Supervised Exercise Program on Pain, Physical Function, and Quality of Life in Patients With Breast Cancer: Protocol for a Randomized Clinical Trial by Jennifer García-Molina, Olalla Saiz-Vázquez, Montserrat Santamaría-Vázquez, Juan Hilario Ortiz-Huerta

“…Physical exercise has been shown to effectively mitigate these side effects and improve the quality of life in patients with breast cancer. ObjectiveThis randomized clinical trial aims to evaluate the efficacy of a 12-week supervised exercise program on pain, physical function, and quality of life in female patients with cancer. …”
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Improvement of Motor Imagination and Manual Ability Through Virtual Reality and Selective and Nonselective Functional Electrical Stimulation: Protocol for a Randomized Controlled T... by Montserrat Santamaría-Vázquez, J Hilario Ortiz-Huerta, Aitor Martín-Odriozola, Olalla Saiz-Vazquez

“…MethodsThis clinical randomized controlled trial (RCT)with 4 branches will involve 80 healthy university students, with blinded third-party assessment. …”
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Circuit training intervention for cognitive function, gut microbiota, and aging control: study protocol for a longitudinal, open-label randomized controlled trial by Keishi Soga, Michio Takahashi, Akari Uno, Takamitsu Sinada, Kentaro Oba, Keisei Kawashima, Yasuko Tatewaki, Taizen Nakase, Yasuyuki Taki

“…Therefore, this study aims to elucidate the effects of long-term circuit training on cognitive function through a comprehensive analysis of factors such as gut microbiota and proteins related to aging control. …”
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Contralesional Cathodal Transcranial Direct Current Stimulation Does Not Enhance Upper Limb Function in Subacute Stroke: A Pilot Randomized Clinical Trial by Danielle De S. Boasquevisque, Larissa Servinsckins, Joselisa P. Q. de Paiva, Daniel G. dos Santos, Priscila Soares, Danielle S. Pires, Jed A. Meltzer, Ela B. Plow, Paloma F. de Freitas, Danielli S. Speciali, Priscila Lopes, Mario F. P. Peres, Gisele S. Silva, Shirley Lacerda, Adriana B. Conforto

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Walking Exercise and Its Effect on Functional Capacity and Productivity in Post-Coronary Artery Bypass Graft (CABG) Patients: A Randomized Controlled Trial by Indra Gilang Pamungkas, Tuti Herawati, Prima Agustia Nova

“…Data analysis used independent and dependent t-tests for normally distributed variables such as functional capacity, impairment while working, and activity impairment, and Mann-Whitney and Wilcoxon tests for variables that were not normally distributed, such as work time missed and overall work impairment. …”
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Time to return of bowel function following perioperative probiotics in colorectal cancer surgery (PICCS-1): study protocol for a randomized controlled trial by Dedrick Kok Hong Chan, Bei En Siew, Jerrald Lau, Jasmin Koh, Megan Xin-Hui Lee, Chermaine Ang, Ning Qi Pang, Ker-Kan Tan

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The promoting effects of digital targeted cognitive training in medication treatment for children with ADHD: a randomized controlled trial by Chen Dang, Yu Zhu, Xiangsheng Luo, Lu Liu, Yuan Feng, Guisen Wu, Shaogen Zhong, Xin Wang, Jianzhao Zhang, Yike Zhu, Siqi Liu, Ziqi Liu, Li Qin, Xiaohui Ma, Yufeng Wang, Xiaoyi Wang, Jian Yang, Changming Wang, Li Sun

“…Improving cognitive functions alongside medication treatment is crucial for better outcomes. …”
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Therapeutic Role of Additional Mirror Therapy on the Recovery of Upper Extremity Motor Function after Stroke: A Single-Blind, Randomized Controlled Trial by Xin Wen, Li Li, Xuelian Li, Huanghong Zha, Zicai Liu, Yang Peng, Xuejin Liu, Huiyu Liu, Quan Yang, Jing Wang

“…Rehabilitation of upper extremity hemiplegia after stroke remains a great clinical challenge, with only 20% of patients achieving a basic return to normal hand function. How to promote the recovery of motor function at an early stage is crucial to the life of the patient. …”
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Effects of a Digital Functional Exercise Program on the Disease Activities and Physical Capabilities of Patients With Ankylosing Spondylitis: Protocol for a Randomized Controlled T... by Xingkang Liu, Xiaojian Ji, Lidong Hu, Tianyu Jiang, Ang Min, Lulu Zeng, Yiwen Wang, Meihui Zhao, Jian Zhu, Feng Huang, Changshui Weng, Zheng Zhao

“… BackgroundAnkylosing spondylitis (AS), a chronic inflammatory disease, causes spinal stiffness, functional impairment, and reduced quality of life. …”
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Causal associations between liver function biomarkers and prostate cancer risk in European and East Asian populations: a univariate, multivariable, and bidirectional Mendelian Rand... by Xinyu Xu, Wenjing Zhu, Yu Peng

“…This study employed Mendelian Randomization (MR) to investigate the genetic causal relationship between liver function markers and PCa in European and East Asian populations. …”
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Genetic evidence suggests a causal relationship linking thyroid function to prospective memory and dementia and Parkinson’s disease by Yang Wang, Yanying Liu, Huimin Yang, Zhuang Mo, Haiyan Liu, Qi Yu

“…Abstract Epidemiological studies suggest a link between thyroid function and prospective memory (PM), but more evidence is required. …”
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Data normalization in machine learning by V. V. Starovoitov, Yu. I. Golub

“…Perhaps due to this property, the random forest classifier, as a result of numerous experiments, is recognized as one of the best classifiers in the analysis of data of different nature.…”
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Integrative Genomic and Functional Approaches Identify FUOM as a Key Driver and Therapeutic Target in Cervical Cancer by Wenzhi Jiao, Shanshan Liu, Jianwei Shi, Minmin Yu

“…Functional enrichment and Gene Set Variation Analysis (GSVA) revealed their involvement in key pathways. scRNA‐seq explored cell‐specific expression patterns and immune cell infiltration in the tumor microenvironment (TME). …”
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Identification of comorbid genes between type 2 diabetes and migraine through peripheral blood single-cell and Mendelian randomization analysis by Bobo Yuan, Jianrui Li, Qing Shu, Xiaoye Wang, Guogang Luo, Ranran Ma

“…This study integrates single-cell data and Mendelian randomization (MR) analysis to identify comorbidity-associated genes and elucidate potential mechanistic links between these two conditions. …”
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