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The Causal Relationship Between Asthma and Hippocampal Volume: A Study Based on Bidirectional Mendelian Randomization Analysis
Published 2025-05-01“…Methods In this study, we employed a two‐sample Mendelian randomization (MR) analysis, utilizing large‐scale genome‐wide association study (GWAS) data to systematically investigate the potential causal relationship between asthma and hippocampal volume. …”
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302
Effects of therapeutic interventions on long COVID: a meta-analysis of randomized controlled trialsResearch in context
Published 2025-09-01“…Methods: In this meta-analysis, we searched PubMed, Cochrane Library, Embase, Web of Science, SPORTDiscus (EBSCO), CINAHL (EBSCO), and Rehabilitation & Sports medicine source (EBSCO) from inception to July 20, 2025, for randomized controlled trials (RCTs) evaluating exercise training, respiratory muscle training, telerehabilitation, transcranial direct current stimulation (tDCS), olfactory training, palmitoylethanolamide with luteolin (PEA-LUT), and steroid sprays in adults with Long COVID. …”
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303
Finite element comparative study on creep and random vibrations of solder joints in BGA package
Published 2025-06-01“…As the demand for increasing miniaturisation and functionality of electronic devices soars, understanding the creep and random vibration of solder joints (SJs) in BGA packages in devices is critical to achieving high device reliability. …”
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304
Effects of Physical Exercise on Executive Function in Schizophrenia: Systematic Review and Meta-Analysis
Published 2025-04-01“…Executive functions are often impaired in individuals with schizophrenia spectrum disorders. …”
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305
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Bioinformatic and Mendelian Randomization Analyses of Correlation Between Differentially Expressed Genes and Prognosis of Oral Squamous Cell Carcinoma Patients
Published 2025-02-01“…The biological function of genes with high prognostic value was further evaluated by single gene differential analysis. …”
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Combined Mendelian randomization and quantitative proteomics analysis to study the influence of thyroid dysfunction on acute ischemic stroke
Published 2024-12-01“…We combined Mendelian randomization (MR) and tandem mass tag (TMT)‐based quantitative proteomics analysis to study the influence of thyroid dysfunction on AIS. …”
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309
Laser Acupuncture for the Pain of Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Published 2025-08-01“…Low evidence showed that laser acupuncture may improve the knee functioning of KOA patients compared to placebo acupuncture on 240-point WOMAC (WMD − 39.06, 95% CI − 63.79 to − 14.32).Conclusion: Based on the low-certainty evidence from our meta-analysis, the effects of laser acupuncture on pain intensity compared to exercise are uncertain. …”
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310
Transcriptome sequencing and Mendelian randomization analysis identified biomarkers related to neutrophil extracellular traps in diabetic retinopathy
Published 2024-10-01“…Additional analysis, including nomogram construction, gene set enrichment analysis, drug prediction and molecular docking, were performed to investigate the functions and molecular mechanisms of the key genes. …”
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311
Mendelian randomization analysis reveals the potential of the IKZF1 gene as a therapeutic target in colorectal cancer
Published 2025-05-01“…Our analysis identified IKZF1 as a significant therapeutic target through colocalization analysis. …”
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Platelet rich plasma versus corticosteroids for lateral epicondylitis: a meta-analysis of randomized clinical trials
Published 2025-02-01“…Results Twenty-six randomized controlled trials with 1.877 patients were included in this meta-analysis. …”
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314
The Effects of Specific Gut Microbiota on Hyperuricemia — A Mendelian Randomization Analysis and Clinical Validation
Published 2025-06-01“…However, the specific functional microbial biomarkers and their roles in HUA remain underexplored.Methods: Based on this, we hypothesize that the Mendelian randomization (MR) analysis method can be used to identify and define microbial biomarkers associated with HUA. …”
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315
Non‐alcoholic fatty liver disease and heart failure: A comprehensive bioinformatics and Mendelian randomization analysis
Published 2024-12-01“…This study investigates their shared biomarkers and causal relationships using bioinformatics and Mendelian randomization (MR) approaches. Methods We analysed NAFLD and HF datasets from the Gene Expression Omnibus (GEO). …”
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316
Identification and Functional Analysis of PANoptosis‐Associated Genes in the Progression From Sepsis to ARDS
Published 2025-01-01“…Mendelian randomization analysis was applied to investigate potential causal links between specific PRGs and ARDS. …”
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317
The effect of curcumin supplementation on cognitive function: an updated systematic review and meta-analysis
Published 2025-04-01“…BackgroundPrevious randomized controlled trials (RCTs) did not draw a consistent conclusion about the effect of curcumin on cognitive function.MethodsWe searched Web of Science, PubMed, Cochrane Library and Embase, and 9 RCTs (including 12 independent comparisons) with 501 subjects were included in the present meta-analysis.ResultsCompared with placebo, supplementation of curcumin significantly improved global cognitive function (SMD, 0.82; 95% CI, 0.19 to 1.45; p = 0.010). …”
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318
A meta-analysis of the influence of traditional Chinese exercises on cognitive function in the elderly
Published 2025-04-01“…BackgroundThis study seeks to assess the impact of traditional Chinese exercises (Tai Chi, Baduanjin, Yijinjing, Wuqinxi, and Liuzijue) on cognitive function in older adults through a systematic review and meta-analysis. …”
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319
Efficacy of acupuncture for functional constipation in elderly: a systematic review and meta-analysis
Published 2024-12-01“…There have been no published reviews or meta-analyses regarding the use of acupuncture in treating functional constipation in older adults. Therefore, we carried out a meta-analysis to assess the impact of acupuncture on elderly patients dealing with functional constipation.MethodsThis study retrieved randomized controlled trials (RCTs) on acupuncture therapy for functional constipation in the elderly from several electronic databases, including Embase, PubMed, Cochrane Library, Wanfang Database, Chinese BioMedical Literature Database, and China National Knowledge Infrastructure. …”
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320
Transcriptomic analysis reveals the function of m6A regulators in aged cochlea
Published 2025-05-01“…Methods: We sequenced the transcriptome from the cochleae of six young (2-mo) and six old mice (24-mo) bioinformatics analysis. Differential expression analysis and downstream functional analysis was performed to identify m6A regulators. …”
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