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    Quantitative evaluation of China's adolescent physical activity policies: a PMC Index model approach by Xinzhu Huang, Changsheng Zhang, Jiang Li, Xianming Ding

    Published 2025-07-01
    “…This paper first constructs PMC-Index model, then conducts quantitative analysis on the text, and finally calculates the scores of nine policies in various dimensions to analyze the advantages and disadvantages of the policies. …”
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    Perturbation-response analysis of in silico metabolic dynamics revealed hard-coded responsiveness in the cofactors and network sparsity by Yusuke Himeoka, Chikara Furusawa

    Published 2025-05-01
    “…Understanding the dynamics of biochemical systems when subjected to perturbations is essential for the development of a quantitative theory of homeostasis. In this study, we analyze the response of bacterial metabolism to externally imposed perturbations using kinetic models of Escherichia coli’s central carbon metabolism in nonlinear regimes. …”
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    ChatGPT's perspectives on real numbers, straight lines, and probability—A quantitative study on the influence of prompting by Frederik Dilling

    Published 2025-07-01
    “…A qualitative content analysis of 450 ChatGPT responses to the mathematical concepts of real numbers, straight lines and probability and the subsequent quantitative evaluation with chi-square tests showed that the empirical-concrete perspective occurs much more frequently than the other perspectives and the formal-abstract perspective is found very rarely in comparison. …”
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    A nomogram based on quantitative MR signal intensity predicts early response to combined systemic treatment in patients with hepatocellular carcinoma by Ran Tao, Haohao Lu, Xiangjun Dong, Qian Qian Ren, Hongjie Fan, Zhaoming Tang, Xiangwen Xia

    Published 2025-03-01
    “…ObjectiveThis study aimed to develop and evaluate the value of a nomogram based on quantitative MR signal intensity to predict response to combined systemic therapy of anti-angiogenesis and immune checkpoint inhibitor (ICI) in hepatocellular carcinoma (HCC) patients.Methods117 HCC patients who underwent the combined systemic treatment at a tertiary hospital between September 2020 and May 2024 were enrolled and divided into a development cohort (n = 82) and a validation cohort (n = 35). …”
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  9. 49

    Quantitative analysis of transient and sustained transforming growth factor‐β signaling dynamics by Zhike Zi, Zipei Feng, Douglas A Chapnick, Markus Dahl, Difan Deng, Edda Klipp, Aristidis Moustakas, Xuedong Liu

    Published 2011-05-01
    “…The TGF‐β pathway elicits a transient signaling response to a single pulse of TGF‐β stimulation, whereas it is capable of integrating repeated pulses of ligand stimulation at short time interval, resulting in sustained phospho‐Smad2 and transcriptional responses. …”
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    A quantitative framework for tree–soil interaction mechanisms in expansive clay: Field investigation and empirical modeling by Xi Sun, Jie Li, You Gao, Xin Liu, Annan Zhou

    Published 2025-08-01
    “…Although vegetation-induced moisture changes are known to affect ground movement, quantitative characterization of tree–soil interactions remains limited due to insufficient field data and unclear relationships between tree water uptake and soil response. …”
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  11. 51

    Quantitative Evaluation of Macao’s Education Policy: A PMC Index Modeling Approach Incorporating Text Mining by Rongjiang Cai, Xi Wang, Tao Zhang

    Published 2024-11-01
    “…Taking the policy addresses of the Macau Special Administrative Region over the past 25 years as the research sample, this study pioneered the use of policy modeling consistency index modeling combined with text mining to construct an evaluation system featuring the development of education policies. …”
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    Modeling omics dose-response at the pathway level with DoseRider by Pablo Monfort-Lanzas, Johanna M. Gostner, Hubert Hackl

    Published 2025-01-01
    “…A number of tools have been developed for dose-response modeling and various thresholds have been defined as a quantitative representation of the effect of a substance, such as effective concentrations or benchmark doses (BMD). …”
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    Expression and Localization of hspa5 in Response to Thermal Stress in the Spotted Sea Bass (Lateolabrax maculatus) by Xiaoqiang LIU, Chunhui FENG, Haishen WEN, Yun LI, Tianyu JIANG, Xin QI

    Published 2025-08-01
    “…Sequence comparison and conserved domain analysis revealed that L. maculatus HSPA5 exhibited higher homology with bony fish than with mammals or birds and possessed a conserved domain characteristic of the HSP70 superfamily. Structural modeling indicated that the secondary structure of HSPA5 was predominantly composed of α-helices, accompanied by some irregular coiling.To investigate the response mechanism of hspa5 in L. maculatus under high-temperature stress, we analyzed its expression in liver tissue using real-time quantitative polymerase chain reaction (qPCR) under a 30 ℃ heat stress condition. …”
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    Quantitative structure-activity relationship study of some angiotensin-converting enzyme inhibitor drugs in the treatment of hypertension based on Monte Carlo optimization method by Shahram Lotfi, Shahin Ahmadi, Ali Azimi

    Published 2025-05-01
    “…The QSAR model of split 2 calculated by TF3 was found to be the best model, and it identified structural attributes responsible for the increase and decrease of inhibitory activity.…”
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    In Vitro Prediction of Skin-Sensitizing Potency Using the GARDskin Dose–Response Assay: A Simple Regression Approach by Robin Gradin, Fleur Tourneix, Ulrika Mattson, Johan Andersson, Frédéric Amaral, Andy Forreryd, Nathalie Alépée, Henrik Johansson

    Published 2024-08-01
    “…In conclusion, the results suggest that the GARDskin Dose–Response assay may be used to derive an accurate quantitative continuous potency estimate of skin sensitizers.…”
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