Commiphora myrrha resin extract-modulated cytochrome P-450 2C9 enzyme expression in cultured Hep G2 cells is associated with resin extract-derived metabolites binding to Pregnane X... by Amani Alsharidah, Zeyad Alehaideb, Sahar S. Alghamdi, Rasha S. Suliman, Saleh Althenayyan, Feras Almourfi, Bader Hazazi, Aljawharah Almogren, Abeer Al Tuwaijri, Mohamed Boudjelal, Afrah Alkhuriji, Sabine Matou-Nasri

“…CYP 2C9 gene and protein expression levels were evaluated using reverse transcription-quantitative polymerase chain reaction and Western blot. …”
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CD81-guided heterologous EVs present heterogeneous interactions with breast cancer cells by Elena Gurrieri, Giulia Carradori, Michela Roccuzzo, Michael Pancher, Daniele Peroni, Romina Belli, Caterina Trevisan, Michela Notarangelo, Wen-Qiu Huang, Agata S. A. Carreira, Alessandro Quattrone, Guido Jenster, Timo L. M. Ten Hagen, Vito Giuseppe D’Agostino

“…In time-frames where the global EV distribution did not change between HER2-positive (SK-BR-3) or -negative (MDA-MB-231) breast cancer cell lines, the HER2 exposure in isogenic cells remarkably affected the tropism of heterologous EVs, demonstrating the specificity of antiHER2 EVs representing about 20% of secreted bulk vesicles. …”
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The effect of heat-sensitive moxibustion in the elderly with nocturia: protocol for a randomized controlled trial by Jinhua Geng, Jinhua Geng, Xintong Ma, Yihui Lin, Qiaoli Lin, Qiaoli Lin, Kaitian Wen, Kaitian Wen, Chunyan Ruan, Chunyan Ruan, Zunjiang Li, Zunjiang Li, Zhaofan Mo, Shuang Li, Banghan Ding, Banghan Ding, Na Liu, Na Liu

“…Additionally, several secondary outcomes will be evaluated, including sleep quality, quality of life scores, the efficacy of traditional Chinese medicine (TCM) syndrome, and changes in blood biomarkers Arginine vasopressin (AVP) and Atrial natriuretic peptide (ANP). …”
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Effectiveness of wellness program interventions to improve physician wellness: a systematic review by Nikola Kolobaric, Benjamin Milone, Maria Salman, Amos Buh, Nandini Biyani, Gamal Wafy, Stephen G Fung, Mekaylah Scott, Rohan Kiska, Rachel Kang, Kathryn Lee, Sarah Syed, Maya Gibb, Shan Dhaliwal, Daniel Myran, Courtney Maskerine, Pierre Antoine Brown, Ayub Akbari, Gregory L. Hundemer, Peter Tanuseputro, Deena Fremont, Edward Spilg, Manish M. Sood

“…Peer reviewed published studies that qualitatively and/or quantitively measured outcomes of wellness interventions for practicing physicians were included. …”
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What happens between first symptoms and first acute exacerbation of COPD – observational study of routine data and patient survey by Alex Bottle, Alex Adamson, Xiubin Zhang, Benedict Hayhoe, Jennifer K Quint

“…SABA use changed little. These were maintained into the COVID era. …”
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Improving health-promoting workplaces through interdisciplinary approaches. The example of WISEWORK-C, a cluster of five work and health projects within Horizon-Europe by Deborah De Moortel, Michelle C Turner, Ella Arensman, Alex Binh Vinh Duc Nguyen, Víctor Gonzalez

“…Digitalization, green transitions, and demographic change are transforming societies and economies across Europe. …”
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Oral–gut microbiome axis in a Korean cohort with inflammatory bowel disease and ankylosing spondylitis (INTEGRATE): a prospective and observational study protocol by June-Young Lee, Tae-Hwan Kim, Sungsin Jo, Yeon-Ah Lee, Sang Won Lee, Chang Kyun Lee, Bora Nam, Soo-Kyung Park, Hyun Sik Kim, Bo-Hyung Kim, Shin Ju Oh, Jae-Yun Lee, Dong Il Park

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Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. by Madalene Earp, Jonathan P Tyrer, Stacey J Winham, Hui-Yi Lin, Ganna Chornokur, Joe Dennis, Katja K H Aben, Hoda Anton-Culver, Natalia Antonenkova, Elisa V Bandera, Yukie T Bean, Matthias W Beckmann, Line Bjorge, Natalia Bogdanova, Louise A Brinton, Angela Brooks-Wilson, Fiona Bruinsma, Clareann H Bunker, Ralf Butzow, Ian G Campbell, Karen Carty, Jenny Chang-Claude, Linda S Cook, Daniel W Cramer, Julie M Cunningham, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Evelyn Despierre, Jennifer A Doherty, Thilo Dörk, Andreas du Bois, Matthias Dürst, Douglas F Easton, Diana M Eccles, Robert P Edwards, Arif B Ekici, Peter A Fasching, Brooke L Fridley, Aleksandra Gentry-Maharaj, Graham G Giles, Rosalind Glasspool, Marc T Goodman, Jacek Gronwald, Philipp Harter, Alexander Hein, Florian Heitz, Michelle A T Hildebrandt, Peter Hillemanns, Claus K Hogdall, Estrid Høgdall, Satoyo Hosono, Edwin S Iversen, Anna Jakubowska, Allan Jensen, Bu-Tian Ji, Audrey Y Jung, Beth Y Karlan, Melissa Kellar, Lambertus A Kiemeney, Boon Kiong Lim, Susanne K Kjaer, Camilla Krakstad, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D Le, Shashi Lele, Jenny Lester, Douglas A Levine, Zheng Li, Dong Liang, Jolanta Lissowska, Karen Lu, Jan Lubinski, Lene Lundvall, Leon F A G Massuger, Keitaro Matsuo, Valerie McGuire, John R McLaughlin, Iain McNeish, Usha Menon, Roger L Milne, Francesmary Modugno, Kirsten B Moysich, Roberta B Ness, Heli Nevanlinna, Kunle Odunsi, Sara H Olson, Irene Orlow, Sandra Orsulic, James Paul, Tanja Pejovic, Liisa M Pelttari, Jenny B Permuth, Malcolm C Pike, Elizabeth M Poole, Barry Rosen, Mary Anne Rossing, Joseph H Rothstein, Ingo B Runnebaum, Iwona K Rzepecka, Eva Schernhammer, Ira Schwaab, Xiao-Ou Shu, Yurii B Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C Southey, Beata Spiewankiewicz, Lara Sucheston-Campbell, Ingvild L Tangen, Soo-Hwang Teo, Kathryn L Terry, Pamela J Thompson, Lotte Thomsen, Shelley S Tworoger, Anne M van Altena, Ignace Vergote, Liv Cecilie Vestrheim Thomsen, Robert A Vierkant, Christine S Walsh, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S Whittemore, Kristine G Wicklund, Lynne R Wilkens, Yin-Ling Woo, Anna H Wu, Xifeng Wu, Yong-Bing Xiang, Hannah Yang, Wei Zheng, Argyrios Ziogas, Alice W Lee, Celeste L Pearce, Andrew Berchuck, Joellen M Schildkraut, Susan J Ramus, Alvaro N A Monteiro, Steven A Narod, Thomas A Sellers, Simon A Gayther, Linda E Kelemen, Georgia Chenevix-Trench, Harvey A Risch, Paul D P Pharoah, Ellen L Goode, Catherine M Phelan

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DFT-analysis of protolytic equivalents of 5-(aryl)-4-(methyl,amino)-1,2,4-triazole-3(2H)-thione by O. A. Bihdan, N. A. Alk Khalaf

“…The use of modern computer methods in aspects of quantum chemistry and systematic analysis of their results give an idea of the reactivity of organic compounds, as well as to understand the essence of known experimental data, correct predictions, and quantitative estimates. Undoubtedly, theoretical calculations are useful in solving such an urgent problem of modern chemistry as prototropic equilibria and properties of substances in the gas phase, solutions, and solid-state. …”
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The role of smell in medical and psychological disorders: An interdisciplinary approach by Giuseppe Riva

“…In 2017, the position paper by Hummel et al. on olfactory dysfunction gave the definitions of qualitative and quantitative smell impairments [1]. Hyposmia is a reduced ability to detect odors, anosmia is the complete inability to detect odors, parosmia is a change in the normal perception of odors, such as when the smell of something familiar is distorted, or when something that normally smells pleasant now smells foul. …”

Preliminary study on early warning value and mechanism of interleukin-1β in extremely severe oral and maxillofacial space infections by ZHU Hanyi, SHI Huan, YU Chuangqi, ZHENG Lingyan

“…Peripheral blood mononuclear cells (PBMCs) from 2 patients in each group (moderate, severe and extremely severe) and 2 healthy controls (GSE224198) were analyzed using single-cell RNA sequencing (scRNA-seq) to identify key pro-inflammatory cell subtypes and genes, and to examine their changing trends with increasing infection severity. …”
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PSMB10 maintains the stemness of chemotherapeutic drug-resistant leukemia cells by inhibiting senescence and cytotoxic T lymphocyte-mediated killing in a ubiquitinated degradation... by Xiao Ma, Yingnan Li, Di Wang, Jialan Niu, Qian Li, Ying Chen, Mengyuan Wang, Jin Wen, Chenxi Liao, Nan Wang, Xiaolan Zhang, Jiwei Chang, Jiayi Yang, Lei Li, Jing Zou, Danyue Peng, Lingbo Liu

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Automated Synthesis and Initial Evaluation of (4′-Amino-5′,8′-difluoro-1′H-spiro[piperidine-4,2′-quinazolin]-1-yl)(4-[18F]fluorophenyl)methanone for PET/MR Imaging of Inducible Nit... by Skye Hsin-Hsien Yeh, Wen-Sheng Huang, Chuang-Hsin Chiu, Chuan-Lin Chen, Hui-Ting Chen, Dae Yoon Chi, Zhengxing Ge, Tsung-Hsun Yu, Pao-Yeh Wang, Yu-Yeh Kuo, Chun-Tse Hung, Geng-Ying Li, Chi-Wei Chang

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Uncovering key regulatory pathways and prognostic biomarkers in the tumor microenvironment of high-grade serous ovarian cancer through single-cell RNA sequencing and experimental v... by Yue Li, Long Zhao, Ying Tian, Qianqian Zhou, Xia Liu, Shucai Yang, Jinfeng Xu, Chang Zou, Jinling Zhang, Hui Luo

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الاتجاهات الحديثة في تطبيقات الجيوماتكس في دراسات العمليات النهرية by منال سمير شلبى متولى

“…The world has witnessed a rapid change in the use of modern technologies in the study of river processes, through obtaining, collecting, storing, processing and displaying data. …”
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PtrA, Piz-t, and a novel minor-effect QTL (qBR12_3.3–4.4) collectively contribute to the durable blast-resistance of rice cultivar Tainung 84 by Sheng-Shan Wang, Wei-Bin Chang, Ming-Chien Hsieh, Szu-Yu Chen, Dah-Jing Liao, Ching-Ying Liao, Wei-Chiang Shen, Hong-Hua Chen, Chieh-Yi Chen, Yi-Chia Chen, Yueh-Lin Lin, Chih-Wei Tung, Ruey-Shyang Chen, Chia-Lin Chung

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GINS1 Enhances Glycolysis, Proliferation and Metastasis in Lung Adenocarcinoma Cells by Activating the Notch/PI3K/AKT/mTORC1 Signaling Pathway by Yishan HUO, Xiaohui XU, Xiumin MA, Yangchun FENG

“…Western blot and real-time fluorescence quantitative polymerase chain reaction (qRT-PCR) were used to detect the expression of GINS1 in LUAD cell lines A549, SK-LU-1, Calu-3, H1299 and BEAS-2B. …”
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Film Properties of Heparin Cross-Linked with Epichlorohydrin in Absence or Presence of Imidazole by Ivan Šimkovic, Filip Gucmann, Michal Hricovíni, Raniero Mendichi, Edmund Dobročka, Alberto Giacometti Schieroni, Daniele Piovani, Stefania Zappia, Miloš Hricovíni

“…A negligible change in modulus was, however, observed for films cross-linked in the presence of I, or was even reduced by ~15% (1H/1E/3I) compared to that for the H substrate. …”
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Network Meta-Analysis of Factors Influencing the Carbon Sink Capacity of Urban Park Green Spaces by Yutong JI, Tianyi LIN, Lian LIU, Xiong LI

“…In light of the increasingly prominent role of urban green spaces in mitigating climate change, the research also seeks to highlight strategies that balance ecological functions with urban recreational and aesthetic needs.MethodThis research employs the network Meta-analysis method to explore the critical factors influencing the carbon sequestration potential of urban park green spaces, and conduct a systematic quantitative assessment of their respective carbon sink capacity. …”
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Pharmacodynamic study of Gubi granules in the treatment of osteoarthritis by Yingxia Bao, Liyu Hao, Yiqiu Liao, Jianhui Sun, Yiman Chen, Jianliang Li, Hongmei Li, Lingli Wang, Jiansong Wang

“…Results: The results showed that Gubi granules significantly alleviated the pathological changes of osteoarticular tissues, and remarkably decreased the Mankin score of joints and the extent of joint swelling (P < 0.01). …”
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