Effect of antiviral siRNAs on the production of cytokines in vitro by A. V. Pak, E. A. Pashkov, N. D. Abramova, A. V. Poddubikov, F. G. Nagieva, E. A. Bogdanova, E. P. Pashkov, O. A. Svitich, V. V. Zverev

“…The concentration of viral ribonucleic acid (vRNA) and change in the expression of IL-1β and IL-28β (IFN-λ3) were determined by real-time reverse transcription quantitative polymerase chain reaction (real-time RT-qPCR). …”
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Soft skills and the use of industry 4.0 as determinants of professional development in engineering graduates: A SEM approach by Ronald Fernando Davila Laguna, Danny Lizarzaburu Aguinaga, Daniel Enrique Caceres Torres, Benito Armando Larroche Cueto

“…This study investigates the combined influence of soft skills and the use of Industry 4.0 technologies on the professional development of Peruvian engineering graduates, incorporating psychological well-being as a mediating variable. Employing a quantitative, cross-sectional, explanatory design, data were collected from 301 graduates across engineering disciplines. …”
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Network and systems biology approaches help investigate gene regulatory interactions between Salmonella disease and host in chickens: Model‐based in silico evidence combined with g... by Reza Tohidi, Hoda Javaheri Bargourooshi, Arash Javanmard

“…This method normalizes the expression of the target gene to that of actin, an internal control and estimates the change in expression relative to the untreated control. …”
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Efficacy of hydrodynamic debridement in the treatment of burns: a systematic review of randomized controlled trials by ZHAO Jianlei, ZHAO Jingqi, LIU Chang, HUANG Jingjun, JIN Shengyuan

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Victimización LGBTI, espacio y género en España by Ignacio Elpidio Domínguez Ruiz

“…Consequently, this article links not only to a line of queer studies increasingly focused on methodological issues and on the need for the production of empirical and quantitative or mixed data, but also to the trajectory of victimology studies. …”
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Development and Implementation of MyPainHub, a Web-Based Resource for People With Musculoskeletal Conditions and Their Health Care Professionals: Mixed Methods Study by Kerrie Evans, Jonathan Ko, Dragana Ceprnja, Katherine Maka, Darren Beales, Michele Sterling, Kim L Bennell, Gwendolen Jull, Paul W Hodges, Marnee J McKay, Trudy J Rebbeck

“…Following implementation, the information contained on MyPainHub changed knowledge and practice for some patients and HCPs. …”
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Integration of network pharmacology, transcriptomics, and experimental verification to investigate the mechanism of action of cepharanthine hydrochloride against prostate cancer by Zongming Dong, Xiaosa Chang, Xing Luo, Hui Li, Ming Deng, Zeyu Huang, Tingting Chen, Yu Chen, Bishao Sun, Yingbing Wu, Ronghua Wu, Qingjian Wu, Jingzhen Zhu, Ji Zheng

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Inhibition of ALKBH5 demethylase of m6A pathway potentiates HIV-1 reactivation from latency by Haider Ali, Jakub Wadas, Maryam Bendoumou, Heng-Chang Chen, Paolo Maiuri, Antoine Dutilleul, Simona Selberg, Lorena Nestola, Kamil Lalik, Veronique Avettand-Fenoël, Coca Necsoi, Alessandro Marcello, Esko Kankuri, Mati Karelson, Stéphane De Wit, Krzysztof Pyrc, Alexander O. Pasternak, Carine Van Lint, Anna Kula-Pacurar

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Strategies for implementing long‐acting cabotegravir for PrEP in US clinics serving Black women: interim healthcare provider findings from the EBONI study by Katherine L. Nelson, Tammeka Evans Cooper, Yolanda Lawson, Dylan Baker, Satish Mocherla, Megan Dieterich, Theo Hodge, Alftan Dyson, Denise Sutherland‐Philips, Heidi Swygard, Lisa Petty, Peter Jeffery, Kenneth Sutton, Courtney Peasant Bonner, Sara M. Andrews, Samantha Chang, Piotr Budnik, Kimberly Smith, Annemiek deRuiter, Maggie Czarnogorski, Nanlesta Pilgrim

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Characteristics of occurrence and distribution rule of deep coalbed methane in supercritical state by Lihong ZHOU, Xia YAN, Xianyue XIONG, Feng WANG, Wenchao LIU, Yuejie YANG, Zhaobiao YANG, Yanqing FENG

“…The results show that: ① Under high temperature and high pressure, methane viscosity, density, compression factor, volume coefficient and other high pressure physical property parameters do not change linearly with temperature and pressure. Based on the quantitative relationship between high pressure physical property parameters and temperature and pressure, empirical calculation formulas for each parameter are established. ② The distribution law of adsorbed gas and free gas occurrence states in deep CBM is revealed under different thermal evolution degrees, different burial depths and different temperature and pressure conditions. …”
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KEMAMPUAN LITERASI SAINS SISWA SMA DI KOTA KENDARI: DESKRIPSI & ANALYSIS by Erniwati Erniwati, Istijarah istijarah, La Tahang, Hunaidah Hunaidah, Vivi Hastuti Rufa Mongkito, Suritno Fayanto

“…This type of research used descriptive quantitative approach.Data collection techniques use tests which included aspects of context, content, and process. …”
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Physical simulation test study on the stability of wading personnel in mine water inrush roadway by Qiang WU, Yi YAO, Yuanze DU, Huiping LI, Yingwang ZHAO, Hua XU, Shouqiang LIU, Xiao WANG

“…The physical simulation test of the stability of wading personnel on the roadway in a mine water disaster is carried out to reveal the potential law of the stability and safety speed threshold of personnel wading evacuation, to promote the theoretical optimization and quantitative model research and development of intelligent water disaster emergency rescue, and provide scientific support for the study and construction of auxiliary decision-making of intelligent mine water disaster emergency rescue system.…”
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Expression analysis of glutathione S-transferase genes in Lasioderma serricorne (Coleoptera: Anobiidae) subjected to CO₂-enriched atmosphere by XU Kangkang, DING Tianbo, YAN Yi, LI Can, YANG Wenjia

“…Compared with the control, the mRNA levels of LsGSTd1 did not change significantly following exposure to CO₂ stress. …”
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Effect of Thermal-Mechanical Coupling on Gas Permeability Properties and Pore Structure of HTCC by ZHANG Deng-xiang, ZENG Zhe, JIANG Zhong-ming

“…This study systematically investigates the gas permeability property and the evolution mechanism of the micro-pore structure of HTCC under thermal-mechanical coupling from an experimental perspective. A quantitative relationship between operational parameters (e.g., temperature and pressure) and gas permeability property is established, providing references for material selection in energy storage infrastructure. …”
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Logistic and Structural Equation Fitting Analyses of the Effect of Slow-Release Nitrogen Fertilizer Application Rates on the Nitrogen Accumulation and Yield Formation Mechanism in... by Jingjing Shi, Tiantian Meng, Xuanyi Chen, Xiangqian Zhang, Meiren Rong, Huiqing Lan, Guolong Ge, Dejian Zhang, Xiaoqing Zhao, Yonghe Hao, Zhanyuan Lu

“…With the increase in the SRF_N application rate, both the economic yield and biological yield showed a single peak curve change and were maximized in the N240 treatment. The economic yield reached 15,342.07 kg ha⁻¹ in 2020 and 16,323.51 kg ha⁻¹ in 2021, increasing by 36.2% and 61.7% compared with CK, respectively. …”
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Comparison of Biocompatibility of 3D-Printed Ceramic and Titanium in Micropig Ankle Hemiarthroplasty by Si-Wook Lee, Donghyun Lee, Junsik Kim, Sanghyun An, Chul-Hyun Park, Jung-Min Lee, Chang-Jin Yon, Yu-Ran Heo

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Effect of continuous quality improvement on protein energy wasting in maintenance dialysis patients by Chai Lu, Zhang Ying-zi, Liu Jin-hong, Hu Hong

“…Objective To explore the effect of continuous quality improvement（CQI）on protein energy wasting（PEW）in maintenance hemodialysis patients.Methods From July 2016 to June 2017,85 PEW patients undergoing routine hemodialysis at blood purification center were selected.Through the establishment of CQI team and the application of CQI program, the management objects included patients, their families and implementing "PDCA"（plan, do, check & act）during treatment.The observation period lasted 12 months.Serum albumin（Alb）,serum prealbumin（PA）,transferrin（TF）and serum cholesterol（serum）before and after CQI were compared cholesterol Tch, hemoglobin（Hb）,serum creatinine（Scr）,urea nitrogen（BUN）,serum hypersensitive C-reactive protein（hs CRP）,body mass index（BMI）,normalized protein catabolic rate（nPCR）,mid arm circumference（MAC）and mid arm circumference（MAMC）were measured.Serum calcium, phosphorus, parathyroid hormone（iPTH）and modified quantitative and global assessment（MQSGA）were recorded.And the impact of CQI on these indicators was observed.Results After CQI,the average levels of Alb（g/L）,PA（mg/L）,TF（mg/L）,Tch（mmol/L）,Hb（g/L）and BMI（kg/m²）were markedly higher than before（34.34±3.97 vs 37.26±3.33,252.9±41.7 vs 295.1±39.0,1.52±0.24 vs 1.99±0.25,2.93±0.84 vs 4.23±0.97,83.88±16.75 vs 94.12±13.46,27.58±6.84 vs 28.16±5.78,P<0.05）.The average level of hs CRP decreased from（20.85±2.09）to（13.15±1.74）mg/L（t=5.02,P<0.01）,MAC increased from（22.02±1.63）to（24.81±1.26）mm（t=5.02,P<0.01）and MAMC rose from（20.68±1.47）to（22.74±1.40）mm（t=2.603,P=0.017）,nPCR increased from（0.85±0.92）g·kg^-1·d^-1 to（1.21±0.21）g·kg^-1·d^-1（t=1.154,P=0.022）,mild proportion increased from 77.65% to 88.23%（χ²=4.61,P=0.002）,moderate proportion declined from 18.82% to 10.59%（χ²=3.69,P=0.017）and severe proportion dropped from 3.5% to 1.33%（χ²=5.05,P<0.001）.The average level of serum calcium showed little change（t=0.629,P=0.537）,proportion of attaining the standard spiked from 52% to 66.7%（χ²=2.36,P<0.05）;average level of blood phosphorus decreased from（2.11±0.24）to（1.80±0.23）mmol/L（t=-0.459,P<0.05）,average level of iPTH declined from（40.79±18.67）to（24.41±9.82）pmol/L（t=-5.566,P<0.001）and proportion of reaching the standard jumped from 47.62% to 71.43%（χ²=4.69,P<0.001）.Conclusion CQI can significantly improve the comprehensive nutritional status of patients and the proportion of patients with blood calcium, blood phosphorus and iPTH compliance has significantly improved.There is no occurrence of calcium and phosphorus metabolism disorder or secondary parathyroid dysfunction.…”
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ERK2-mediated phosphorylation of ZEB1 at S322 enhances PD-L1 expression and EMT, leading to pancreatic cancer progression by Mi Kyung Park, Hye Ja Lee, Jee Young Sung, Hyun Jung Byun, Hyun Ji Kim, Eun Ji Kim, Tuan Minh Nguyen, Gyeoung Jin Kang, Seung Hyun Oh, Jae Gal Shim, Ho Lee, Ki Taek Nam, Yong Yun Kim, Seung Bae Rho, Sang Gun Kim, Chang Hoon Lee

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Quantifying task-locked information transmission between cortical areas with TMS-EEG by Zhaohuan Ding, Wenbo Ma, Leixiao Feng, Mingsha Zhang, Xiaoli Li

“…This approach provides a novel method for quantifying dynamic changes in connectivity and causality between cortical areas during task processing.…”
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Ecological portraits: Mapping functional spectra and space characteristics of birds in China by Fei Duan, Ming Gao, Shuyi Zhu, Xiaoli Shen, Sheng Li

“…The functions of wildlife species in ecosystems and their responses to environmental changes are mediated through their functional traits. …”
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