Spectrum of mutations and their phenotypic manifestations in children and adults with long QT syndrome by N. N. Chakova, S. M. Komissarova, E. A. Zasim, T. V. Dolmatovich, E. S. Rebeko, S. S. Niyazova, E. V. Zaklyazminskaya, L. I. Plashchinskaya, M. V. Dudko

“…The average diagnostic efficiency of mutation identification using NGS in patients with clinically manifest LQTS was 66%. …”
Get full text

ECONOMIC AND LEGAL PREREQUISITES FOR THE FUNCTIONING OF STARTUPS IN MODERN SOCIETY: ISSUES OF INTERNATIONAL AND NATIONAL LEGAL REGIMES by Viktor Makovii, Rashad Mamedov, Illia Klochko

“…The analysis determined the quantitative and qualitative parameters of the organisational, legal and economic principles of determining startups in modern conditions. …”
Get full text

ORAL HYGIENE STATE AND ITS CORRECTION OPTIONS IN CHILDREN WITH HODGKIN’S DISEASE by L.F. Kaskova, I.Y. Vashchenko, N.V. Yanko

“…The oral hygienic condition was studied using the Pahomov’s hygienic index, the simplified oral hygiene index (OHI-S by Greene and Vermilion), the PHP hygiene hygiene efficiency index (Podshadley, Haley, 1968), the modified Turesky index (1970), and API surfaces [6]. …”
Get full text

Abstract 221: EARLY EXPERIENCE OF EMBOGUARD BALLOON GUIDE CATHETER IN LARGE VESSEL OCCLUSION THROMBECTOMY by Bishow C. Mahat, Raul G. Nogueira, Mohamed Doheim, Priya Nidamanuri, Bharat Pillai, Michael J. Lang, Matthew T. Starr, Nirav R. Bhatt, Marcelo Rocha, Bradley Gross, Alhamza R. Al‐Bayati

“…With the evolving technology and newer generation of catheters and devices, the interest in improving the technical and procedural factors that can help better the recanalization success, clinical outcomes, and efficiency is ever‐growing. Proximal flow arrest with balloon guide catheters (BGC) has been shown to optimize revascularization success and functional outcome in stroke EVT. …”
Get full text

Construction and analysis of a prognostic risk scoring model for gastric cancer anoikis-related genes based on LASSO regression by Ai CHEN, Xiaowei CHEN, Yanan WANG, Xiaobing SHEN

“…Gene expression levels in gastric cancer clinical samples and cells were detected by real-time quantitative PCR (RT-qPCR); Kaplan-Meier (KM) survival curves, univariate and multivariate Cox regression analyses were used to verify the predictive efficiency of the prognostic risk scoring model for the prognosis of gastric cancer patients; CIBERSORT and ESTIMATE algorithms were used to analyze the immune cell infiltration levels in patients with different risk groups; the correlation between risk scores and immune checkpoint expression levels in gastric cancer patients was analyzed using the R package "ggplot2" and "ggExtra", and the correlation between tumor mutation burden (TMB) and risk scores was assessed; chemotherapy drug sensitivity analysis was used to evaluate the value of the constructed prognostic risk scoring model in gastric cancer chemotherapy. …”
Get full text

Nivel de satisfacción de médicos prestadores de servicio social de una universidad pública del sureste mexicano by Diana Velazco-Guillen, Sergio Quiroz-Gomez, Karla del Socorro Celorio-Méndez, Crystell Guadalupe Guzmán-Priego

“…Areas for improvement were identified in financial support, working conditions and administrative efficiency. Together, these findings underscore the need to optimize the social service experience to ensure comprehensive and satisfactory training of future physicians.…”
Get full text

INTERNET SPACE AS A FACTOR OF POLITICAL SOCIALIZATION OF MODERN YOUTH by N. N. Pachina, J. D. Gorodova, G. R. Pachin

“…In conclusion, recommendations are given to improve the efficiency of the process of political socialization in a modern digital society. …”
Get full text

Acceptability, feasibility and appropriateness of integrating HPV self-sampling for cervical cancer screening into voluntary family planning services in Malawi by Patani Mhango, Andrew Kumitawa, Monica Patricia Malata, Jennifer H. Tang, Effie Chipeta, Bianca Kandeya, Medrina Mtende, Princess Kaira, Razak Mussa, Wanangwa Chimwaza, Lameck Chinula, Ireen Magongwa, Jacqueline Mbendera, Eneli Mhango, Eunice Mwandira, Lizzie Msowoya, Jennifer S. Smith, Mitch Matoga, Agatha Bula, Luis Gadama, Victor Mwapasa

“…Providers reported the following positive attributes of service integration and self-sampling: efficiency, reduction in workload (for clinicians and nurses), simplicity of self-sampling, cost-savings (for clients), promotion of women’s privacy and empowerment and reduction of negative myths and misconceptions associated with speculum vaginal examination. …”
Get full text

Utility of advanced training skills among GPs: a systematic review by Hannah Mason, Abdul-Aziz Seidu, Francis Albert, Emma Anderson, Faith Alele, Lawrie McArthur, Aaron Hollins, Paula Heggarty, Tarun Sen Gupta, Richard Hays, Bunmi Malau-Aduli

“…The challenges reported for those undertaking AST programs were barriers to inclusion on remote visits (eg transportation space, training space), time efficiency and management, workload fluctuation, gaps between training and use of skills, peer acknowledgement, and differences between the hospital settings in which training occurred and the rural contexts in which the skills would be applied. …”
Get full text

Proteomic Landscape of Small Extracellular Vesicles Derived From Gastric Juice and Identified TFF2 as a Specific Biomarker by Fan R, Wu K, Yang J, Zhu B, Jiang T, Liu Y, Yuan B, Liu L, Sun Y, Sun X, Liu L, Luo W, Zhou C, Guo Y, Liu L

“…Furthermore, TFF2 was selectively expressed in gsEVs, but not in sEVs derived from other biofluids such as intestinal juice and plasma. The efficiency of TFF2 as a gsEVs biomarker was higher than the commonly used biomarker CD9, CD81, and Syntenin-1. …”
Get full text

Hydrodynamic Features of Gas-Liquid Flow Movement in a Separation Device Plane Channel with an Oscillating Wall by Pavlenko I.V., Liaposhchenko O.O., Sklabinskyi V.I., Ivanov V.O., Gusak O.G.

“…The aim of the research is to increase the efficiency of separation equipment by imposing the vibration impact on a gas-liquid flow. …”
Get full text

Application of Artificial Intelligence using K-Means for Programming Question Assessment by Waliyyudin Waliyyudin, Ichsan Ibrahim

“…The system achieved 87% clustering accuracy, reduced the average grading time to 4.5 seconds per answer (compared to 13 seconds manually—representing a 65% efficiency gain), and decreased the inter-rater score standard deviation from 7.5 to 2.8 points. …”
Get full text

Big data based metro crowd delivery system by Kun-fang ZHANG, Ming-ming LU, Lin ZHENG

“…In recent years,the demand for urban express delivery experiences fast growing.Several startup delivery corporations,such as iShansong,have provided the delivery services,which are promised to deliver a parcel within 1 or 3 hours in a city.However,since the quality of the promised services have not been fully quantitatively analyzed based on real data,it is quite often that couriers refuse to pick up delivery requests or the accepted parcels fail to be delivered on time.To address the above issue,a metro crowd-delivery system was proposed,which could utilize the historical records of metro passengers to analyze the quality of the delivery service and provide differential service within different period of time.The system not only meet the requirements of high delay requirements of the courier,but also as a city-wide express supplement.At the same time,a courier transit program was proposed.Experiments show that this transfer program is efficient.…”
Get full text

Designing a model of the role of social media in crisis management and digital supply chain resilience by Farhad Jahangiri, Abolfazl Danaei, Mahsa Akbari, Younos Vakil Alroaia

“…Given the limited number of qualified individuals, the entire population of experts was included in the study. In the quantitative phase, the target population comprised 500 employees of MAPNA Company. …”
Get full text

Soil moisture characteristics of four artificial plant communities in aerial seeding afforestation area and their response to different levels of rainfall by Tiejun Zhang, Tiejun Zhang, Yanping Liu, Yanping Liu, Jianying Guo, Jianying Guo, Guodong Tang, Guodong Tang, Zhenqi Yang, Zhenqi Yang

“…Studying the characteristics of soil moisture in afforestation area and its response to different grades of rainfall is helpful to quantitatively analyze the change law of soil moisture in afforestation area and provide theoretical basis for rational and efficient use of soil moisture. …”
Get full text

A phase II randomized trial of individualized neoantigen peptide vaccine combined with unusual radiotherapy (iNATURE) in advanced solid tumors-GCOG0028 by Yan Zhang, Yan Zhang, Yan Zhang, Ye-Fan Hu, Ye-Fan Hu, Lingyu Ma, Lingyu Ma, Yifei Wu, Yifei Wu, Dandan Chao, Dandan Chao, Xian Chen, Xian Chen, Zhiyuan Xu, Zhiyuan Xu, Xiaoping Su, Xiaoping Su, Wei Dai, Wei Dai, Wei Dai, Jiandong Huang, Jiandong Huang, Jiandong Huang, Jiandong Huang, Pingfu Fu, Feng-Ming (Spring) Kong, Feng-Ming (Spring) Kong, Feng-Ming (Spring) Kong, Feng-Ming (Spring) Kong

Get full text

Administrative databases as a tool for identifying healthcare demand and costs in an over-one million population by Fabiana Madotto, Michele A Riva, Carla Fornari, Luciana Scalone, Roberta Ciampichini, Chiara Bonazzi, Lorenzo G Mantovani, Giancarlo Cesana

Get full text

Perceptions and reflections of embryo donation recipients: a qualitative follow-up study by Seungho Lee, Salomeh Salari, Mona El-Gayar, Joshua Mangels, Rebecca Flyckt, Jody Madeira, Susan Klock, Steven R Lindheim

“…Objective Cross-sectional quantitative data from donor embryo recipients suggest children conceived through embryo donation are psychosocially well adjusted with healthy parent–child relationships. …”
Get full text

Value Cocreation and Codestruction in Digital Health Services: Protocol for a Systematic Review by Elina Laukka, Tuure Tuunanen, Miia Jansson, Minna Vanhanen, Nina Hirvonen, Jenni Palukka, Märt Vesinurm, Paulus Torkki

“…Value cocreation can be used to both design and efficiently use digital health services trying to maximize the value for patients. …”
Get full text

Modeling the effect of terracing on runoff control in a rural catchment in southern Brazil by Larissa Werle, Jean Paolo Gomes Minella, Gustavo Henrique Merten, Douglas Rodrigo Kaiser, Alexandre Schlesner, Alice Prates Bisso Dambroz, Blayon Eduardo Hammes, Felipe Bernardi

“…Planning conservation practices at the catchment scale through hydrological modeling and monitoring presents an efficient alternative, as it integrates the controlling factors that govern storm runoff dynamics. …”
Get full text