Lipopolymers as the Basis of Non-Viral Delivery of Therapeutic siRNA Nanoparticles in a Leukemia (MOLM-13) Model by Panadda Yotsomnuk, Amarnath Praphakar Rajendran, Daniel Nisakar Meenakshi Sundaram, Luis Carlos Morales, Cezary Kucharski, Mohammad Nasrullah, Wanwisa Skolpap, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Hasan Uludağ

“…Both lipopolymers gave similar-size siRNA complexes (210–220 nm) with positive <i>ζ</i>-potentials (+17 to +25 mV). While the binding efficiency of both lipopolymers to siRNA were similar, PEI1.2k-PHPA-Lin9 complexes were more resistant to heparin-induced dissociation. …”
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Association studies for leaf rust resistance earmark differential genomic regions for silicon (Si) responsiveness in bread wheat (Triticum aestivum L.) by Prashanth Babu, Manjunath Prasad, R. Nirmalaruban, Sudhir Kumar, Rajbir Yadav, Manjeet Kumar, Kiran B. Gaikwad, Naresh Kumar Bainsla, S. Bhaskar Reddy, Nasreen Saifi, Amit Kumar Mazumder, Meda Alekya, Gaurav Kaushik, Palaparthi Dharamteja, Meghashri S. Patil, Shiv Kumar Singh, Dunna Vijay, Ranjeet Ranjan Kumar

“…It plays a significant role in enhancing photosynthetic efficiency, modulating hormonal balance, and activating defence mechanisms through regulating antioxidant systems and expressing defence-related genes, leading to increased stress tolerance and improved yield. …”
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Retrospective Comparative Analysis of Prostate Cancer In-Basket Messages: Responses From Closed-Domain Large Language Models Versus Clinical Teams by Yuexing Hao, MS, Jason Holmes, PhD, Jared Hobson, MD, Alexandra Bennett, MD, Elizabeth L. McKone, MD, Daniel K. Ebner, MD, David M. Routman, MD, Satomi Shiraishi, MD, Samir H. Patel, MD, Nathan Y. Yu, MD, Chris L. Hallemeier, MD, Brooke E. Ball, MSN, Mark Waddle, MD, Wei Liu, PhD

“…This could lead to improved efficiency in health care workflows and reduced costs while maintaining or enhancing the quality of communication between patients and health care providers.…”
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基于DB-FastFAME色谱柱的气相色谱法 测定食用植油脂肪酸组成Determination of fatty acid composition of edible vegetable oil by gas chromatography based on DB-FastFAME column... by 孟庆宇，蒋甜燕,孙日飞，马莉，夏旭明 MENG Qingyu, JIANG Tianyan, SUN Rifei, MA Li, XIA Xuming

“…The method resolution, precision, accuracy and column efficiency were analyzed. The results showed that the DB-FastFAME column could separate 37 fatty acid methyl esters mixed standard within 25 min, and the resolutions were all no less than 1.5, the relative standard deviation (RSD) was less than 0.03% for qualitation and less than 2.3% for quantitation, which indicated that the column had good separation effect and good stability. …”
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AI-Based Noise-Reduction Filter for Whole-Body Planar Bone Scintigraphy Reliably Improves Low-Count Images by Csaba Csikos, Sándor Barna, Ákos Kovács, Péter Czina, Ádám Budai, Melinda Szoliková, Iván Gábor Nagy, Borbála Husztik, Gábor Kiszler, Ildikó Garai

“…<b>Background/Objectives</b>: Artificial intelligence (AI) is a promising tool for the enhancement of physician workflow and serves to further improve the efficiency of their diagnostic evaluations. This study aimed to assess the performance of an AI-based bone scan noise-reduction filter on noisy, low-count images in a routine clinical environment. …”
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Assessment of grain production levels and analysis of obstacle factors in China: a sustainable, stable and green perspective by Caixia Shangguan, Ruijundi Ma, Yan Lu, Hui Zhang, Mingjin Tian, Yongzhong Teng, Li Jing, Xia Zhang, Hongbin Liu, Ke Li, Xingxing Mei

“…Regionally, barriers have shifted from reliance on fiscal support to greater emphasis on local fiscal capacity and resource efficiency.DiscussionBased on existing literature, theoretical analysis, and empirical results, this study proposes policy recommendations including improving yield per unit area and the innovation of scale operation, promoting integrated regional development through a high-quality grain industry model, and advancing digital empowerment and financial coordination to support the full production cycle. …”
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CircRNA-miRNA-mRNA networks in plasma extracellular vesicles as biomarkers for first-onset schizophrenia by Xinzhe Du, Wei Hu, Xinrong Li, Yao Gao, Junxia Li, Xiaodong Hu, Xiao Wang, Wentao Zhao, Long Cheng, Xiaohua Cao, Hongbao Cao, Zhiyong Ren, Yu Zhang, Yong Xu, Sha Liu

“…Here, we constructed circRNA-miRNA-mRNA networks of EVs, and examined their diagnostic efficiency in FOS. Methods The expression levels of circRNAs, miRNAs and mRNAs in EVs derived from 10 FOS patients and 10 healthy controls (HC) were determined by high-throughput sequencing. …”
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Relative vacuum reduction innovative processes applied in primary magnesium production—Comprehensive analysis of thermodynamics, resource, energy flow, and carbon emission by Xiaolong Li, Tingan Zhang, Yan Liu, Junhua Guo, Jingzhong Xu, Yuanyuan Liang

“…This paper offers essential data support and theoretical guidance for achieving energy efficiency, carbon reduction in magnesium smelting, and the industrial adoption of innovative processes.…”
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The effectiveness of cardiac resynchronization therapy in patients with chronic heart failure of various origin depending on the structural myocardial injury in cardiac magnetic re... by O. V. Stukalova, N. A. Mironova, M. D. Utsumueva, S. Yu. Kashtanova, E. A. Butorova, V. N. Shitov, G. S. Tarasovsky, S. P. Golitsyn, S. K. Ternovoy

“…In patients with ischemic HF, size ofLV structural injury does not affect the CRT efficiency, but lateral scar is associated with CRT nonresponse.…”
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Analisis Kualitas Performa Aplikasi Digital Banking X Menggunakan Framework ISO 25010 by Medina Nurul Zahra, Kraugusteeliana Kraugusteeliana

“…The result shows that from seven hypotheses, six hypotheses significantly impact the application's performance efficiency. There is functional suitability with CR score 2,035, compatibility with CR score 2,115, usability with CR score 2,608, reliability with CR score 2,971, security with CR score 3,359, and portability with CR score 1,985. …”
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Fired clay bricks made by incorporating organic additives: A review by LEWO NKONDI Blanca, AZAMA Nilas, BLAYSAT Benoit, de BAYNAST Hélène, MOUTOU PITTI Rostand

“…Optimizing incorporation rates, particle size distribution of additives and drying and firing parameters is therefore essential to guarantee bricks that combine mechanical durability and thermal efficiency. Hence the need to continue exploring the use of organic additives in the production of fired clay bricks remains paramount.…”
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EXPERIMENTAL STUDY OF EFFECTIVENESS OF DEEP FLUORIDATION OF ENAMEL DURING SECONDARY MINERALIZATION OF THE PERMANENT TEETH ENAMEL by H. V. Sorochenko

“…The main pathogenetic direction of caries prevention in this period is to increase the level of mineralization of tooth enamel. High efficiency of caries prevention with fluoride preparations is associated with exposure to fluoride at different stages of dental caries pathogenesis, including the kinetics of the process of mineralization. …”
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Screening and validation of long non-coding RNAs associated with colorectal cancer based on random forest and LASSO regression algorithm by Yujia Zhao, Qian Li, Xintong Cui, Zhiyu Zhang, Yong You, Xiaowen Hou, Yan Wang, Xu Feng

“…Random forest (RF) and LASSO (Least Absolute Shrinkage and Selection Operator (LASSO) regression algorithms were constructed to screen lncRNAs closely related to CRC, and their screening efficiency was verified. Predict the regulatory genes of lncRNA and construct the ceRNA regulatory network of lncRNA-miRNA-mRNA. …”
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SeqSNP-based genic markers reveal genetic architecture and candidate genes for low nitrogen tolerance in tropical maize inbred lines by Pearl Abu, Baffour Badu-Apraku, Beatrice Elohor Ifie, Beatrice Elohor Ifie, John Saviour Yaw Eleblu, Georgina Lala Ehemba, Pangirayi B. Tongoona, Samuel Kwame Offei

“…To enhance breeding efficiency for low nitrogen tolerance, identifying quantitative trait loci (QTLs) in tropical germplasm is crucial to facilitate marker-assisted selection (MAS). …”
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Sensitivity analysis of the INRA 2018 feeding system for ruminants by hybrid local and global approaches: Comparing the contribution of dietary input variables to multiple response... by Seoyoung Jeon, Tristan Senga Kiessé, Sophie Lemosquet, Pierre Nozière

“…The sensitivity of 5 selected animal responses (output variables) to input variables was analyzed: DMI, milk protein yield (MPY), energy in methane (ECH4), nitrogen utilization efficiency (NUE), and the ratio between urine and total N excretion (UN/TN). …”
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Application of fluorescence spectroscopy and laser confocal technology in shale geological evaluation by LI Ping, ZHAI Zheng, WANG Xin, LI Zheng, LIN Jing, HAN Dongmei, AN Tianxia

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Head-to-Head Evaluation of FDM and SLA in Additive Manufacturing: Performance, Cost, and Environmental Perspectives by Maryam Abbasi, Paulo Váz, José Silva, Pedro Martins

“…However, FDM provides notable advantages in cost (approximately 60% lower on a per-part basis), production speed, and energy efficiency. Moreover, from an environmental perspective, FDM is more favorable when using biodegradable PLA or recyclable ABS, whereas SLA resin waste is hazardous. …”
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Cuproptosis-related lncRNAs emerge as a novel signature for predicting prognosis in prostate carcinoma and functional experimental validation by Yangbai- Lu, Jinfeng- Wu, Xianzhe Li, Xianzhe Li, Qu- Leng, Jian- Tan, Hongxing- Huang, Rui- Zhong, Zhenjie- Chen, Yongxin- Zhang

“…Compared to other clinical features, the ClncRNAs signature exhibited higher diagnostic efficiency and performed well in predicting the 1-, 3-, and 5-year progression-free intervals (PFIs) for PCa. …”
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SELF-CORRECTION OF TEACHERS’ PROFESSIONAL BURNOUT by T. F. Orekhova, T. G. Neretina, Т. V. Kruzhilina, P Ledeur

“…The advantage of all proposed methods and techniques, that form a complete correctional and preventive complex, consists in simplicity, availability, safety and efficiency in respect of achievement of a fast, positive, and really notable result; the elements can vary depending on individual needs and features of a personality. …”
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The association of a single-nucleotide variant in the microRNA-146a with advanced colorectal cancer prognosis by Jéssica Silva dos Santos, Gabriella Lucatto Zunta, Amanda Binatto Negrini, Marina Silva Guinda Ribeiro, Carlos Augusto Real Martinez, Marcelo Lima Ribeiro, Gustavo Jacob Lourenço, Manoela Marques Ortega

“…The aim of this study was to evaluate the association of single-nucleotide variant n.60G>C (rs2910164) of microRNA (miR)-146a, related to suppressing of BRCA1/2 DNA repair protein, with the risk and survival of colorectal cancer patients, as well as miR-146a and BRCA1/2 levels and miR binding efficiency. The genotypes were identified in 125 colorectal cancer patients and 276 controls using TaqMan polymerase chain reaction assay. …”
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