Investigation of metabolic processes of alcohol yeast during the fermentation of buckwheat-corn wort by E. M. Serba, E. R. Kryuchkova, L. V. Rimareva, M. B. Overchenko, N. I. Ignatova, S. V. Pavlenko

“…The optimal ratio of corn and buckwheat in the composition of the grain mixture (7:3) was selected, which made it possible to improve the biochemical and technological parameters of grain must, increase the efficiency of the vital processes of yeast and alcoholic fermentation, ensure an increase in the yield of alcohol by 1.8%, reduce the formation of side metabolites, especially higher alcohols, and change their composition in the direction of increasing the proportion of aldehydes and esters, which can have a positive effect on the organoleptic characteristics of the distillate.…”
Get full text

Induction of Cytoplasmic dsDNA and cGAS-STING Immune Signaling After Exposure of Breast Cancer Cells to X-ray or High-Energetic Carbon Ions by Cristina Totis, MSc, Nicole B. Averbeck, PhD, Burkhard Jakob, PhD, Maik Schork, PhD, Gaia Volpi, MSc, Dennis F. Hintze, BSc, Marco Durante, PhD, Claudia Fournier, PhD, Alexander Helm, PhD

“…Results: We show here that carbon ions induced a significantly higher yield of cytosolic dsDNA fragments per unit dose as compared to photons. The higher efficiency also translated in expression and release of interferon-β by the tumor cells. …”
Get full text

Carboxymethyl Dextran-Based Biosensor for Simultaneous Determination of IDO-1 and IFN-Gamma in Biological Material by Zuzanna Zielinska, Anna Sankiewicz, Natalia Kalinowska, Beata Zelazowska-Rutkowska, Tomasz Guszcz, Leszek Ambroziak, Miroslaw Kondratiuk, Ewa Gorodkiewicz

“…This study introduced a novel method for the simultaneous quantitative determination of IDO-1 and IFN-γ in different biological samples/materials. …”
Get full text

Type 1 diabetes prevention clinical trial simulator: Case reports of model‐informed drug development tool by Juan Francisco Morales, Marian Klose, Yannick Hoffert, Jagdeep T. Podichetty, Jackson Burton, Stephan Schmidt, Klaus Romero, Inish O'Doherty, Frank Martin, Martha Campbell‐Thompson, Michael J. Haller, Mark A. Atkinson, Sarah Kim

“…Despite more than 100 years since the discovery of insulin, teplizumab remains the only FDA‐approved therapy to delay progression from Stage 2 to Stage 3 T1D. To increase the efficiency of clinical trials seeking this goal, our project sought to inform T1D clinical trial designs by developing a disease progression model‐based clinical trial simulation tool. …”
Get full text

Bta-Let-7d Modulation of Oxidative Stress Induced by Potassium Permanganate in Bovine Endometrial Cells via IGF1R/PI3K/AKT Signaling Pathway by Wenjing Liu, Talha Umar, Wen Feng, Bohan Zhang, Jinxin Zhang, Han Zhou, Nuoer Chen, Ganzhen Deng, Siyu Xiao

“…Oxidative stress is a significant factor affecting reproductive efficiency in dairy cows, contributing to conditions such as endometritis that impair fertility and milk production. …”
Get full text

Microscopic pore-fracture combination types and their impact on exploration and development: in case of deep shale gas reservoirs in the Luzhou area of the Sichuan Basin by Zhiming Hu, Zhiming Hu, Xianggang Duan, Xianggang Duan, Yonghong Fu, Yan Chang, Yan Chang, Jin Chang, Jin Chang, Yuqiang Jiang, Linyao Yu

“…This research holds significant theoretical and practical implications for identifying optimal shale gas development zones and improving gas recovery efficiency.…”
Get full text

In-situ graphene modified pencil graphite electrode for the simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid by Pham Van Dat, Le Khanh Toan, Pham Huyen Thuong, Nguyen Van Anh, Nguyen Van Thuc, Nguyen Xuan Viet

“…The binder-free integration of graphene onto the graphite substrate significantly enhanced the electron transfer efficiency compared to the bare PGE, resulting in a 7.8-fold increase in the standard heterogeneous electron transfer rate constant (keff0) and a 2.3-fold increase in the electrochemically active surface area. …”
Get full text

Complex mechanical-thermal synthesis of nanostructured calcium hydrosilicates for cement composites by Evgeny A. Shoshin, Denis K. Timokhin, Alexander V. Strakhov, Maria P. Kochergina, Georgy A. Korolkov

“…The reason for this lies in their high efficiency as accelerators in the absence of a negative effect on the long-term strength and durability of cement composites. …”
Get full text

hMPV Outbreaks: Worldwide Implications of a Re-Emerging Respiratory Pathogen by Alexandra Lianou, Andreas G. Tsantes, Petros Ioannou, Efstathia-Danai Bikouli, Anastasia Batsiou, Aggeliki Kokkinou, Kostantina A. Tsante, Dionysios Tsilidis, Maria Lampridou, Nicoletta Iacovidou, Rozeta Sokou

“…Advances in molecular diagnostics, particularly reverse transcription–quantitative polymerase chain reaction (RT-qPCR) and metagenomic next-generation sequencing (mNGS), have improved detection accuracy and efficiency. …”
Get full text

Hygienic Monitoring of Working Area Air Pollution by Particulate Matter of ticagrelator in the Pharmaceutical Factory by I. A. Pozharnov, A. S. Simakov, N. A. Shulga, A. Yu. Savchenko, O. I. Perederyaev, L. S. Synkova, Yu. V. Medvedev, E. N. Fisher

“…Subsequently, the quantification of ticagrelor in samples was carried out by the method of high-efficiency liquid chromatography with UV detection (HPLC-UV).Results and discussions. …”
Get full text

Drying kinetics and characteristics of Acori tatarinowii rhizoma under hot air thin-layer drying at different temperatures by Yingna Le, Kun Shi, Chengfu Wang, Jingying Guo, Yaohui Ye, Yuexing Ma, Ruiping Wang, Fangyan Cai, Shaolong Ma, Jinlian Zhang, Lingyun Zhong

“…By resolving the longstanding knowledge gap in ATR post-harvest processing, the work establishes quantitative criteria for industrial drying optimization, offering a science-based framework to balance efficiency and phytochemical quality.…”
Get full text

Supercritical carbon dioxide extraction of essential oils from Madhuca Longifolia flowers and its characterization by Achala Gupta, Mohammed A. Bareen, Priyanka Prasad, Anita Srivastava, Jatindra K. Sahu, Hariprasad P

“…The study aimed to assess the effect of extraction methods on the quantitative and qualitative divergence in the chemical composition of flavor compounds of mahua flower EO. …”
Get full text

Research on Dynamic Mechanical Properties and Numerical Simulation of Broken Coal-Rock Grouting Consolidation Bodies by Jiaxin Huo, Changxing Zhu, Xinming Chen, Jiaqi Guo, Huazhe Jiao, Liyou Zhang, Yu Xu, Mingzhi Wang, Xiangfei Jin

“…These findings provide quantitative technical guidance for optimizing grouting material selection and reinforcement strategies in coal-rock engineering applications.…”
Get full text

Cost-benefit analysis and sustainability considerations in starting a restaurant: A case study from Sri Lanka by Sahan Perera, Dunith Abeyaratne, Kavindu Nimesh, Sakith Dewnith, Yasas Sri, Methuli Mewanya, Haritha Perera, Kavindi Wathsala, Sarasi Perera, Thilina Jayathilaka, Nuwan Jayarathna

“…The adoption of eco-friendly practices, such as waste reduction, portion control, and the use of technology for inventory management, further enhances the restaurant's operational efficiency and aligns with the United Nations' Sustainable Development Goals. …”
Get full text

Integrating large language models in biostatistical workflows for clinical and translational research by Steven C. Grambow, Manisha Desai, Kevin P. Weinfurt, Christopher J. Lindsell, Michael J. Pencina, Lacey Rende, Gina-Maria Pomann

“… Abstract Introduction: Biostatisticians increasingly use large language models (LLMs) to enhance efficiency, yet practical guidance on responsible integration is limited. …”
Get full text

Early pregnancy diagnosis in cows using corpus luteum blood flow analysis based on colour Doppler ultrasonography and mRNA analysis by Malshani De Silva, Devinda Wickramasingha, Nirodha Abayalath, Basil Alexander, Missaka Wijayagunawardane, Kai Fai Lee, Suranga Kodithuwakku

“…Abstract Background Reproductive efficiency is paramount in the dairy industry, where early pregnancy detection of dairy cows will allow to detect the non-pregnant animals early, thus enabling to re-synchronize them and getting them pregnant leading to decrease in calving interval, which, in turn, is critical for maximizing productivity and economic gain. …”
Get full text

Possibilities of Complex Ultrasound Examination in the Assessment of Hemodynamic and Structural Features of Retinal Capillary Hemangioma by V. V. Neroev, T. N. Kiseleva, P. A. Ilyukhin, K. A. Ramazanova, M. A. Ryabina, A. Y. Novikova

“…The follow-up efficiency evaluation of the laser coagulation of RCH was performed in 12 eyes. …”
Get full text

Changes in the expression of genes involved in cell cycle regulation and the relative telomere length in the process of canceration induced by omethoate by Xiaoran Duan, Yongli Yang, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Suxiang Liu, Lei Li, Wu Yao, Liuxin Cui, Wei Wang

“…Organophosphorous pesticides (OPs), with high efficiency, broad-spectrum and low residue, are widely used in China. …”
Get full text

Sustainable synthesis of iron-doped manganese oxide nanoparticles for effective photo-accelerated detoxification of tetracycline by Sanjay S. Majani, M. A. Veena, C. M. Hemanth Kumar, Poojitha B. Sridhara Setty, Muzaffar Iqbal, Chandan Shivamallu, Charley A. Cull, Kristin E. Hales, Paul R. Broadway, Raghavendra G. Amachawadi, Shiva Prasad Kollur

“…Additionally, the quantitative aspects of precursor elements were confirmed through XPS studies. …”
Get full text

Medical Data over Sound—CardiaWhisper Concept by Radovan Stojanović, Jovan Đurković, Mihailo Vukmirović, Blagoje Babić, Vesna Miranović, Andrej Škraba

“…The CardiaWhisper system is evaluated across several performance parameters, including functionality, complexity, speed, noise immunity, power consumption, range, and cost-efficiency. Quantitative measurements of the signal-to-noise ratio (SNR) were performed in various realistic indoor scenarios, including different distances, obstacles, and noise environments. …”
Get full text