Adapting the World Health Organization’s Surgical Safety Checklist to High-Income Settings: A Hybrid Effectiveness-Implementation Trial Protocol by Nathan Turley, MA, MBA, Karolina Kogut, BA, Barbara Burian, PhD, Rachel Moyal-Smith, DrPH, PA-C, James Etheridge, MD, MPH, Yves Sonnay, MScPH, William Berry, MD, MPH, Alan Merry, MD, MBChB, Alexander Hannenberg, MD, Alex B. Haynes, MD, MPH, Roger D. Dias, MD, PhD, MBA, Kathryn Hagen, MD, George Molina, MD, MPH, Lisa Spruce, DNP, RN, Carla Williams, RN, MHSM, Mary E. Brindle, MD, MPH, FRCSC

“…The proposed study aims to assess users’ perceptions of a surgical safety checklist (SSC) reimplementation toolkit and its impact on SSC attitudes and operating room (OR) culture, meaningful checklist use, measures of surgical safety, and OR efficiency at 3 different hospital sites. Background:. …”
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Identification of genetic loci and candidate genes regulating photosynthesis and leaf morphology through genome-wide association study in Brassica napus L. by Keqi Li, Na Guo, Na Guo, Miao Zhang, Yuanyuan Du, Jiali Xu, Shimeng Li, Jinxiong Wang, Rongrong Wang, Xiang Liu, Mengfan Qin, Yu Xu, Yunlin Zhu, Jia Song, Aixia Xu, Zhen Huang

“…However, its photosynthetic efficiency, a pivotal determinant of yield, remains relatively low compared with other C3 plants such as rice and soybean, highlighting the necessity of identifying the genetic loci and genes regulating photosynthesis in rapeseed. …”
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Entropy-Regularized Attention for Explainable Histological Classification with Convolutional and Hybrid Models by Pedro L. Miguel, Leandro A. Neves, Alessandra Lumini, Giuliano C. Medalha, Guilherme F. Roberto, Guilherme B. Rozendo, Adriano M. Cansian, Thaína A. A. Tosta, Marcelo Z. do Nascimento

“…Six backbone architectures (ResNet-50, DenseNet-201, EfficientNet-b0, ResNeXt-50, ConvNeXt, CoatNet-small) were trained, with and without our modifications, on five H&E-stained datasets. …”
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Chemical analysis using miniaturized and Portable 3D printed systems: Where are we now? by Miryam Perrucci, Imran Ali, Fotouh R. Mansour, Halil I. Ulusoy, Songül Ulusoy, Abuzar Kabir, Ornella Abollino, Agnese Giacomino, Paolo Inaudi, Marcello Locatelli, Erika Maria Ricci

“…Interest in miniaturized systems is further fueled by the theoretical principle that reducing flow rates enhances the surface-to-volume ratio, thereby improving detection sensitivity.Building on this theoretical foundation—particularly the goals of portability, efficient sampling, and on site analysis—innovative approaches such as microfluidics and 3D printing have been employed to develop compact fluidic systems. …”
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Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine by Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng‐Ming (Spring) Kong, Gen Yang

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Control of Physical and Biochemical Parameters Influencing Exogeneous Cargo Protein Association to Extracellular Vesicles Using Lipid Anchors Enables High Loading and Effective Int... by Antonin Marquant, Jade Berthelot, Claudia Bich, Zeineb Ibn Elfekih, Laurianne Simon, Baptiste Robin, Joël Chopineau, David Tianpei Wang, Samuel Jay Emerson, Aijun Wang, Clément Benedetti, Simon Langlois, Laurence Guglielmi, Pierre Martineau, Anne Aubert‐Pouëssel, Marie Morille

“…By thoroughly characterising Lipid‐PEG‐protein anchorage, this study evidences the interest of this tunable and controllable approach for efficient EV protein delivery.…”
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Sustainable science or business as usual? Exploring awareness and actions in German University Laboratories by Caterina Baars, Patrycja Karwasiecka, João Henrique Paulino Pires Eustachio, Andrea Dobri, Jelena Barbir, Sven Kannenberg, Walter Leal Filho

“…One of the key findings is that the inclusion of more sustainable laboratory activities (e.g. efficient waste and equipment management) was mostly undertaken by the laboratory staff themselves, which led to many bottom-up approaches. …”
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Visual detection of Coxsackievirus A6 using a reverse transcription polymerase spiral reaction method by Kun Wang, Yuanhang Ai, Juan Luo, Longying Liang, Weiwei Zhang, Guojun Cao, He Zha, Jie Wu, Kun Lei, Shifei Yao, Kaifeng Wu

“…Given its significant role in these diseases, there is an urgent need for an efficient identification method. This study presents a novel visual approach based on the reverse transcription polymerase spiral reaction (RT-PSR) for the rapid detection of CVA6. …”
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Assessment of urban traffic vehicle emissions reduction after integration of ‘traffic light countdown’ module in navigation by Minghui Zhang, Di Liu, Wenkai Qin, Jing Wang, Hao Fu, Qianxi Liu, Xifan Chen, Xiangmin Li, Hao Wang, Nana Qin, Sixian Qin, Siyuan Wang

“…This initiative aims to improve vehicle traffic efficiency, reduce transportation carbon emissions, and enhance public driving safety simultaneously. …”
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dVP_FAM—development and evaluation of a transsectoral digital care platform for individuals with familial cancer risks: study protocol for a multi-centre, cluster-randomised, mixed... by K. Klein, F. Kendel, S. Schüürhuis, K. Neumann, C. Kowalski, P. Thomas, T. Reinhold, U. Felbor, S. Stegen, C. Schmid, N. Mehrhof, S. Asmussen, F. Diel, M.A. Feufel, D. Speiser

“…Secondary outcomes include improvements in care efficiency, patient empowerment, and health-related quality of life. …”
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Applications of machine learning in potentially toxic elemental contamination in soils: A review by Yan Li, Bao Xiang, Tianyang Wang, Yinhai He, Xiaoyang Liu, Yancheng Li, Shichang Ren, Erdan Wang, Guanlin Guo

“…From these findings, ML techniques, through their powerful data processing capabilities, provide new perspectives and tools for the efficient assessment and management of soil PTEs contamination.…”
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AlphaBind, a domain-specific model to predict and optimize antibody–antigen binding affinity by Aditya A. Agarwal, James Harrang, David Noble, Kerry L. McGowan, Adrian W. Lange, Emily Engelhart, Miranda C. Lahman, Jeffrey Adamo, Xin Yu, Oliver Serang, Kyle J. Minch, Kimberly Y. Wellman, David A. Younger, Randolph M. Lopez, Ryan O. Emerson

“…These models enable efficient in silico prescreening and optimization of antibody candidates. …”
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LLM in the Loop: A Framework for Contextualizing Counterfactual Segment Perturbations in Point Clouds by Veljka Kocic, Niko Lukac, Dzemail Rozajac, Stefan Schweng, Christoph Gollob, Arne Nothdurft, Karl Stampfer, Javier del Ser, Andreas Holzinger

“…By leveraging the reasoning capabilities of LLMs, we generate perturbations that are not only computationally efficient but also semantically meaningful. The proposed framework undergoes rigorous evaluation, combining human inspection of LLM-generated suggestions with quantitative analysis of semantic classification model performance across different LLM variants. …”
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Orchestrated Cu2+-coordinated tetracycline-porphyrin self-assembly remodels tumor microenvironment for photo-enhanced immuno-chemodynamic therapy by Xianbin Sun, Xinyi Wang, Xudong Li, Ya Wang, Ruofei Xu, Xinyi Shen, Ding Tan, Jingjing Liao, Haijun Chen, Yu Gao, Jianping Zheng

“…These findings provide key insights into developing orchestrated metal-coordinated nanotherapeutics by repurposing existing therapeutic agents, enabling the design of multifunctional systems that integrate efficient chemodynamic activity, TME remodeling, and immune activation for effective nanodynamic therapy.…”
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A promoter library for tuning gene expression in Cupriavidus necator under autotrophic conditions by Wataru Kitagawa, Wataru Kitagawa, Kensuke Igarashi, Ryo Nagasawa, Shigeyuki Kakizawa, Mizuki Horino, Kosuke Fujishima, Kosuke Fujishima, Toshiaki Fukui, Souichiro Kato, Souichiro Kato, Souichiro Kato

“…This advancement lays the groundwork for more efficient CO2-based biomanufacturing platforms, contributing to the development of sustainable bioprocesses.…”
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The value of using patient‐reported outcomes for health screening during long‐term follow‐up after paediatric stem cell transplantation for nonmalignant diseases by Joëll E. Bense, Nicole Guilonard, Femke Zwaginga, Anne M. Stiggelbout, Marloes Louwerens, Hilda Mekelenkamp, Arjan C. Lankester, Arwen H. Pieterse, Anne P. J. dePagter

“…Results From the patient‐interviews (N = 15) four themes were extracted: use of PROs (1) help to discuss topics; (2) make the patients feel understood; (3) create a moment of self‐reflection; and (4) make consultations more efficient. Pre‐ and postimplementation analysis of PREMs (N = 40) did not show significant differences in terms of patient‐centeredness. …”
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CRISPR-Cas12a/Aurora Deoxyribozyme Cascade: A Label-Free Ultrasensitive Platform for Rapid <i>Salmonella</i> Detection by Cong Shi, Huimin Tan, Zhou Yu, Weilin Li, Yan Man, Qinghai Zhang

“…This cascade ultimately enables quantitative target analysis through fluorescence signal attenuation. …”
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Risk assessment of an Aedes flavivirus and its effect on pathogenic flavivirus replication in mosquitoes by Yumei Fu, Wan Zhao, Shaohui Wu, Jinqian Li, Qing Liu, Feng Jiang, Hong Lu, Le Kang, Qianfeng Xia, Feng Cui

“…Abstract Background Mosquitoes are efficient vectors of medically significant flaviviruses and serve as hosts for insect-specific flaviviruses (ISFs). …”
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Secondary impacts of the COVID-19 pandemic at a tertiary children’s hospital in Canada: a mixed-methods study by Catherine Diskin, Annie Fecteau, Eyal Cohen, Arpita Parmar, Jeremy Friedman, Blossom Dharmaraj, Tanvi Agarwal, Kelly McNaughton, Alia Sunderji, David Faraoni, Jason Fischer, Jason Maynes

“…Themes including (1) timeliness of care, (2) disruption of patient-centred care, (3) new pressures in the provision of safe and efficient care and (4) inequity in the experience of the COVID-19 pandemic emerged, each impacting patients, their families and healthcare providers.Conclusion Being aware of the breadth of the impact of the COVID-19 pandemic across all of the identified themes is important to enable the delivery of timely, safe, high-quality, family-centred paediatric care moving forward.…”
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Dietary creatine improves the growth performance, antioxidant capacity and energy metabolism of common carp (Cyprinus carpio) by activating glucose metabolism and the Nrf2-Keap1 pa... by Meiqi Xing, Xinchi Shang, Longwu Geng, Haijun Wei, Xinghua Che, Xiaodan Shi, Zhengwei Li, Hailong He, Wei Xu

“…The growth data revealed that the addition of 0.5 g/kg creatine significantly increased the weight gain rate (WGR), specific growth rate (SGR), feed efficiency ratio (FER), and protein efficiency ratio (PER) of common carp (P < 0.05). …”
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