Weighted Gene Co-Expression Network Analysis Identifies Hub Genes Governing Resistance to <i>Fusarium oxysporum</i> f. sp. <i>niveum</i> in Watermelon (<i>Citrullus lanatus</i>) by Chen Zhang, Xufeng Fang, Jing Zhang, Xinying Wang, Zhao Liu, Shusen Liu, Zhengfeng Song, Peng Gao, Feishi Luan

“…To elucidate the molecular mechanisms underlying FW resistance in watermelon, we tracked the infection process via microscopy, identifying three critical time points (1, 6, and 8 days post-inoculation) corresponding to spore germination, hyphal invasion of the xylem vascular system, and symptom onset, respectively. …”
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Real-World Study on Implementation of Genomic Tests for Advanced Lung Adenocarcinoma in Brazil by Rodrigo Dienstmann, Leonard M. da Silva, Fernanda Orpinelli Ramos do Rego, Amanda Muniz Rodrigues, Fernanda Christtanini Koyama, Layla Testa Galindo, Carolina de Bustamante Fernandes, Bruno Batista de Souza, Rafael Duarte Paes, Tatiane Montella, Pedro de Marchi, Breno Jeha Araújo, Bruno Lemos Ferrari, Clarissa Mathias, Emilio Pereira, Mariano Gustavo Zalis, Chesley Leslin, Carlos Gil Ferreira

“…Here, we describe the initial implementation of a tailored tissue molecular journey at Oncoclínicas Precision Medicine Laboratory in Brazil, which includes fast-track (FT) non–next-generation sequencing (NGS) assays combined with a broad NGS panel.METHODSFrom 2021 to 2023, all nonsquamous lung cancer samples eligible for the patient support program “Lung Mapping Consortium” at Oncoclínicas & Co were evaluated using the FT panel (immunohistochemistry for PD-L1 and anaplastic lymphoma kinase [ALK], polymerase chain reaction for EGFR and BRAF, and fluorescence in situ hybridization for ROS1) plus a broad DNA and RNA sequencing panel of 180 genes (custom ARCHER panel).RESULTSFrom 1,272 samples received by the laboratory, 3% had no tissue for any molecular testing, 20% was not eligible for broad NGS panel as per pathologist assessment (tumor purity and quantity), additional 12% did not reach presequencing analytical thresholds (nucleic acid quantity and/or quality), and 3% had postsequencing failure. …”
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Game Multiplayer “Mini Car Circuit” Berbasis Android by Syaifuddin Yudha Saputra, Subari Subari

“… Game merupakan program permainan bertujuan untuk menghibur. Game yang paling efektif untuk menghilangkan stres adalah game yang mudah dipelajari, tetapi memiliki tujuan yang sulit dicapai. …”
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A national study of clinical discussions about cannabis use among Veteran patients prescribed opioids by Tauheed Zaman, Dawn M. Bravata, Amy Byers, Erin Krebs, Samuel Leonard, Charles Austin, Friedhelm Sandbrink, Deborah S. Hasin, Salomeh Keyhani

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Evaluating spoke facilitation costs of implementing TelePain in the Veterans Health Administration by Alexandra L. Rose, Shaina Coogan, Jess Indresano, Steven B. Zeliadt, Jessica A. Chen

“…Methods Using an established time-based activity tracker designed for implementation facilitation, study staff tracked minutes spent on implementation activities at 11 spoke sites. …”
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Genetic and environmental contributions to epigenetic aging across adolescence and young adulthood by Dmitry V. Kuznetsov, Yixuan Liu, Alicia M. Schowe, Darina Czamara, Jana Instinske, Charlotte K. L. Pahnke, Markus M. Nöthen, Frank M. Spinath, Elisabeth B. Binder, Martin Diewald, Andreas J. Forstner, Christian Kandler, Bastian Mönkediek

“…Abstract Background Epigenetic aging estimators commonly track chronological and biological aging, quantifying its accumulation (i.e., epigenetic age acceleration) or speed (i.e., epigenetic aging pace). …”
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COMMENTARY: LEARNER-BASED LISTENING AND TECHNOLOGICAL AUTHENTICITY by Richard Robin

“…Effective users of raw electronic resources, such as easily repeatable video clips, captions, and even translation bots will bring a wider variety of input at the proper level for a broader range of learning styles than could possibly be made available in any pre-packaged closed-track program.In listening comprehension, attention over the last twenty-five years has turned from adapted scripts to authentic audio and video in which we scaffold "real media" with remediated tasks (pre- and post-script activities) instead of changing the media itself. …”
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Assessing the impacts of sustainability teaching at higher education institutions by Walter Leal Filho, Laís Viera Trevisan, Subarna Sivapalan, Muhammad Mazhar, Aristea Kounani, Marcellus Forh Mbah, Ismaila Rimi Abubakar, Newton R. Matandirotya, Maria Alzira Pimenta Dinis, Bruno Borsari, Rikki Abzug

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Toxoplasma gondii parasites induce a localized myeloid cell immune response surrounding parasites in the brain during acute infection by Stephanie B. Orchanian, Sebastian Zolog, Julia Tomasello, Rijul Malik, Ji-Hun Shin, Anita A. Koshy, Melissa B. Lodoen

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Efficacy of minimally invasive vascular interventions assessed with mobile multispectral near-infrared spectroscopy by Alisha Roberta Oropallo, MD, Amit Rao, MD, Jo Ann Eisinger, PA, Larry Leonardi, PhD

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Feasibility of post-stroke hand rehabilitation supported by a soft robotic hand orthosis in-clinic and at-home by Natalie Tanczak, Tegan Kate Plunkett, Sijie Lin, Lorena Kuenzler, Megan Lau, Wee Keong Christopher Kuah, Chwee Yin Ng, Roger Gassert, Karen Chua, Olivier Lambercy

“…Feasibility was assessed with therapy dose (repetitions and time) and adherence to the suggested at-home rehabilitation program. Functional improvements were tracked using clinical assessments across time points. …”
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Accompanying Therapy in the Surgical Treatment of Pathological Fractures of the Long Bones and Chronic Fractures of the Trochanteric Region by A. A. Antonov, A. К. Antonov, K. A. Antonov, Yu. K. Antonov, R. V. Gorenkov, R. N. Komarov, V. A. Kochemasov, A. F. Lazarev, A. V. Simonova, E. I. Solod, I. A. Talipov

“…As a result, most of the unwanted symptoms disappeared, time spent in hospital decreased, the psychoemotional status and immunity improved, the functional state of the body was optimized, and the quality of life improved.CONCLUSION The use of new accompanying therapy, the authors’ method of surgical treatment of patients with pathological (metastatic) fractures of the long bones, chronic fractures of the trochanteric region allows us to successfully and effectively operate on such severe patients and perform a fast track surgery program in the early postoperative period.…”
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M2 microglia-derived small extracellular vesicles modulate NSC fate after ischemic stroke via miR-25-3p/miR-93-5p-TGFBR/PTEN/FOXO3 axis by Qian Zhang, Yan Yi, Tiange Chen, Ying Ai, Ziyang Chen, Ganzhi Liu, Zexuan Tang, Jianwei Chen, Tao Xu, Xin Chen, Jinfang Liu, Yuguo Xia

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Development and feasibility testing of a new device for home-based leg heat therapy in patients with lower extremity peripheral artery disease by Bohyun Ro, MSc, John P. Spence, BBA, Paul A. Spence, MD, Christian Buckley, BS, Raghu L. Motaganahalli, MD, Bruno T. Roseguini, PhD

“…All participants completed the 12-week program without serious adverse events, indicating that leg HT is safe and well-tolerated. …”
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Exploring challenges in implementing antimicrobial stewardship interventions across eight African nations: A multi case study by Ms Maxencia Nabiryo, Miss Maxencia Nabiryo, Dr Helena Rosado, Miss Frances Garraghan, Miss Claire Brandish, Miss Victoria Rutter

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EPA guidance on lifestyle interventions for adults with severe mental illness: A meta-review of the evidence by Isabel Maurus, Sarah Wagner, Johanna Spaeth, Anastasia Vogel, Susanne Muenz, Valentina Seitz, Peter von Philipsborn, Marco Solmi, Joseph Firth, Brendon Stubbs, Davy Vancampfort, Mats Hallgren, Tamás Kurimay, Markus Gerber, Christoph U. Correll, Wolfgang Gaebel, Hans-Jürgen Möller, Andrea Schmitt, Alkomiet Hasan, Peter Falkai

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Detecting, Attributing, and Projecting Global Marine Ecosystem and Fisheries Change: FishMIP 2.0 by Julia L. Blanchard, Camilla Novaglio, Olivier Maury, Cheryl S. Harrison, Colleen M. Petrik, Denisse Fierro‐Arcos, Kelly Ortega‐Cisneros, Andrea Bryndum‐Buchholz, Tyler D. Eddy, Ryan Heneghan, Kelsey Roberts, Jacob Schewe, Daniele Bianchi, Jerome Guiet, P. Daniel van Denderen, Juliano Palacios‐Abrantes, Xiao Liu, Charles A. Stock, Yannick Rousseau, Matthias Büchner, Ezekiel O. Adekoya, Cathy Bulman, William Cheung, Villy Christensen, Marta Coll, Leonardo Capitani, Samik Datta, Elizabeth A. Fulton, Alba Fuster, Victoria Garza, Matthieu Lengaigne, Max Lindmark, Kieran Murphy, Jazel Ouled‐Cheikh, Sowdamini S. Prasad, Ricardo Oliveros‐Ramos, Jonathan C. Reum, Nina Rynne, Kim J. N. Scherrer, Yunne‐Jai Shin, Jeroen Steenbeek, Phoebe Woodworth‐Jefcoats, Yan‐Lun Wu, Derek P. Tittensor

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Switch to mania after acute antidepressant treatment for bipolar depression: a systematic review and network meta-analysis of randomised controlled trialsResearch in context by Vincenzo Oliva, Michele De Prisco, Enrico La Spina, Sofia Paolucci, Giovanna Fico, Gerard Anmella, Diego Hidalgo-Mazzei, Andrea Murru, Maurizio Pompili, Michele Fornaro, Marco Solmi, Ayşegül Yildiz, Stefan Leucht, Eduard Vieta, Joaquim Radua

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Development of a Customizable Web-Based Dashboard for Remote Blood Pressure Monitoring: Feasibility and Usability Implementation Study by Joshua Wollen, Thuy Nguyen, Charles Coton, Gina DeWildt, Gabretta Cooksey, Audrey Cohen, Nicholas Hoang, Munachi Okpala, Michael Gonzalez, Mengxi Wang, Chigozirim Izeogu, Elmer Bernstam, Charles Green, Sean Savitz, Jose-Miguel Yamal, Anjail Sharrief

“…Clinicians can analyze, track, and interpret monitored data in near real-time, remotely, which may enhance BP management approaches, particularly in communities with limited access to care. …”
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Study protocol for a multi-session randomized sham-controlled trial of PCC- and amygdala-targeted neurofeedback for the treatment of PTSD by Jonathan M. Lieberman, Ruth A. Lanius, Jean Théberge, Benicio N. Frey, Paul A. Frewen, Frank Scharnowski, David Steyrl, Tomas Ros, Maria Densmore, Emma Tassinari, Vangel Matic, Niki Hosseini-Kamkar, Sandhya Narikuzhy, Fardous Hosseiny, Rakesh Jetly, Andrew A. Nicholson

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