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  1. 2601

    Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy. by Fredrik Barrenäs, Scott G Hansen, Lynn Law, Connor Driscoll, Richard R Green, Elise Smith, Jean Chang, Inah Golez, Taryn Urion, Xinxia Peng, Leanne Whitmore, Daniel Newhouse, Colette M Hughes, David Morrow, Kurt T Randall, Andrea N Selseth, Julia C Ford, Roxanne M Gilbride, Bryan E Randall, Emily Ainslie, Kelli Oswald, Rebecca Shoemaker, Randy Fast, William J Bosche, Michael K Axthelm, Yoshinori Fukazawa, George N Pavlakis, Barbara K Felber, Slim Fourati, Rafick-Pierre Sekaly, Jeffrey D Lifson, Jan Komorowski, Ewelina Kosmider, Danica Shao, Wenjun Song, Paul T Edlefsen, Louis J Picker, Michael Gale

    Published 2021-07-01
    “…The differential IL-15 gene set response to vaccination strongly correlated with the pre-vaccination activity of this pathway, with reduced baseline expression of IL-15 response genes significantly correlating with higher vaccine-induced induction of IL-15 signaling and subsequent vaccine protection, suggesting that a robust de novo vaccine-induced IL-15 signaling response is needed to program vaccine efficacy. …”
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    Expanding HIV Self-Test Kits via Community Pharmacies in Rwanda Has Improved Availability, but Affordability Remains an Issue by Nsengimana A, Biracyaza E, Manirakiza A, Nsekonziza Y, Niyonsenga E, Ntirenganya F, Umumararungu T

    Published 2024-12-01
    “…Amon Nsengimana,1 Emmanuel Biracyaza,2 Augustin Manirakiza,3 Yvette Nsekonziza,3 Emmanuel Niyonsenga,3 Frederic Ntirenganya,4 Théoneste Umumararungu3 1USAID Global Health Supply Chain Program-Procurement and Supply Management (GHSC-PSM) Project, Kigali, Rwanda; 2School of Rehabilitation Faculty of Medicine, Université de Montréal, Montreal, QC, Canada; 3Department of Pharmacy, University of Rwanda, Kigali, Rwanda; 4Department of HIV/AIDS, Diseases Prevention and Control, Rwanda Biomedical Centre (RBC), Kigali, RwandaCorrespondence: Amon Nsengimana, Email amonnsengimana@gmail.comBackground: The World Health Organization (WHO) recommends HIV self-testing (HIVST) to complement the existing HIV testing services. …”
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