Programmed death ligand 1 (PD-L1) expression in gastric cancer: literature review by T. N. Sotnikova, N. V. Danilova, P. G. Malkov, T. V. Polushkina

“…Tumor cells express programmed death ligand 1 (PD-L1), which binds to its programmed death receptor 1 (PD-1). …”
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Ocular adverse events in PD-1 and PD-L1 inhibitors by James Murray, Howard Streicher, Elad Sharon, LeAnne Young, Shanda Finnigan, H Nida Sen, Helen X Chen

“…Background Programmed death-1 (PD-1) and programmed death-ligand 1 (PD-L1) inhibitors can cause unique immune-related adverse effects due to non-specific immunological activation. …”
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A bibliometric analysis of research on PD-1/PD-L1 in urinary tract tumors by Yongming Chen, Xiaojin Lu, Genyuan Peng, Shengjie Liu, Miao Wang, Huimin Hou

“…Programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) are key components in immune checkpoint studies across various tumors, including those in the urinary tract. …”
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Acasunlimab, an Fc-inert PD-L1×4-1BB bispecific antibody, combined with PD-1 blockade potentiates antitumor immunity via complementary immune modulatory effects by Maria Jure-Kunkel, Christina Yu, Nora Pencheva, Mark Fereshteh, Alexander Muik, Aras Toker, Özlem Türeci, Tahamtan Ahmadi, Ugur Sahin, Brandon W Higgs, Jordan M Blum, Saskia M Burm, Vanessa M Spires, Angelica Sette, Sina Fellermeier-Kopf, Andrea Imle, Michela Capello, Kristin Strumane, Theo Plantinga, Craig J Thalhauser, Kristina B Nürmberger, Patricia Garrido Castro, Carol Costa Sa, Bruna de Andrade Pereira

“…Acasunlimab (DuoBody-PD-L1×4-1BB) is an investigational, bispecific antibody designed to elicit an antitumor immune response via conditional 4-1BB activation strictly dependent on simultaneous programmed death-ligand 1 (PD-L1) binding. …”
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In silico study of properties in the series of 1-alkyl-4-(((5-nitrofuran-2-yl)methylene)amino)- 1,2,4-triazole halides by L. I. Kucherenko, T. S. Brytanova, A. S. Hotsulia

“…The ligands have been prepared with the software MarvinSketch 6.3.0, Hyper Chem 8, and AutoDockTools-1.5.6, whereas the software packages Discovery Studio 4.0 and AutoDockTools-1.5.6 have been used for the preparation of enzymes. …”
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Real-world clinical impact of first-line immune checkpoint inhibitor-based therapy in advanced esophageal squamous cell carcinoma by M. Tamba, K. Chin, H. Osumi, M. Ogura, S. Fukuoka, S. Udagawa, K. Shimozaki, K. Yoshino, T. Wakatsuki, E. Shinozaki, K. Yamaguchi, A. Ooki

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The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity by Jian Liu, Junli Ding, Liang Chen, Shoupeng Shao, Jie Mei, Xuejing Yang

“…Conclusions Formin-like protein 1 is a biomarker of an inflamed tumor microenvironment and positively modulates epithelial–mesenchymal transition and programmed cell death 1 ligand 1 expression in pancreatic cancer, which could be utilized as a novel target for antitumor immunity for more in-depth studies.…”
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In silico evaluation of the pharmacodynamic component of the interaction of S-alkyl derivatives of 5-methyl-4-(p-tolyl)-1,2,4-triazole-3-thiol with some biological targets by O. I. Panasenko, V. M. Odyntsova, A. S. Hotsulia

“…A computer method (molecular docking) for predicting and evaluating the interaction between a ligand molecule and a target protein structure. Ligand preparation was performed using MarvinSketch 6.3.0, Hyper Chem 8, and AutoDockTools-1.5.6 programs. …”
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Predictive biomarkers for targeted therapy in daily anatomic pathology for ovarian tumors by Niti Sureka, Sufian Zaheer

“…Emerging biomarkers like programmed death-ligand 1 (PD-L1) expression and angiogenesis markers such as VEGF further enhance therapeutic strategies, paving the way for combination treatments in refractory and relapsed cases. …”
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Research progress of HGF/c-Met signaling pathway in oral squamous cell carcinoma by SHI Jiafan, GONG Lingling, SUN Mingze, LIU Lulu, ZHANG Huilin, LI Ming

“…However, HGF/c-Met can also mediate immune escape by promoting lactate secretion increase, inducing programmed death ligand 1 (PD-L1) expression upregulation, activating and expanding myeloid-derived suppressor cells, and promoting the proliferation of regulatory T cells (Tregs). …”
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