DPImpute: A Genotype Imputation Framework for Ultra‐Low Coverage Whole‐Genome Sequencing and its Application in Genomic Selection by Weigang Zheng, Wenlong Ma, Zhilong Chen, Chao Wang, Tao Sun, Wenjun Dong, Wenjing Zhang, Song Zhang, Zhonglin Tang, Kui Li, Yunxiang Zhao, Yuwen Liu

“…Remarkably, DPImpute demonstrated accurate SNP imputation from low‐coverage sequencing data from single blood cells and single blastocyst cells, highlighting its potential in embryo GS. …”
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The mechanism of RNA methylation writing protein-related prognostic genes in lung adenocarcinoma based on bioinformatics by Sha Yin, Guangyan Luo, Lei Luo

“…The identified prognostic genes also play significant roles in immune cell infiltration in LUAD. This study provides new theoretical references for subsequent in-depth research on LUAD.…”
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The possibilities of optical coherence tomography of the anterior segment in the angio mode (AS-OCTA) in the diagnosis and tactics of surgical treatment of corneal diseases by B.E. Malyugin, S.Yu. Kalinnikova, R.S. Isabekov, O.P. Antonova, A.V. Fomin

“…Fremont, California, USA) in the «OCT» and «Angio OCT» modes using the AngioVue program and the SSADA algorithm. Results. In the presented clinical cases, the use of AS-OCTA makes possible to accurately assess the depth, area and architectonics of the vessels, and helps to determine the tactics of surgical treatment and type of keratoplasty. …”
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Bone marrow composition features and possibilities of tumor involvement diagnosing in patients with classic Hodgkin’s lymphoma by F. M. Abbasbeyli, P. A. Zeynalova, M. A. Vernyuk, A. A. Fedenko, T. Yu. Mushkarina, A. A. Melnikova, V. Yu. Kovalskaya, L. Yu. Grivtsova

“…In addition, it was found that the majority of cases with CD20+/± and CD15+/± expression in the primary tumor were observed in the group of patients without bone marrow involvement. when assessing the cellular composition of bone marrow aspirates, it was revealed that in patients with bone marrow tumor infiltration, an increase in cellularity and megakaryocytes number along with a decrease in the plasma cells number is observed.   Conclusion. The results suggest further study of bone marrow immunomorphological features in order to identify prognostic factors and search for new therapeutic targets. a more extended analysis of bone marrow aspirate immunomor-phological characteristics using new modern diagnostic methods, minimal residual disease status as a surrogate marker seems to be relevant and necessary to confirm the depth of the antitumor response achieved. …”
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A network-based approach to overcome BCR::ABL1-independent resistance in chronic myeloid leukemia by Valeria Bica, Veronica Venafra, Giorgia Massacci, Simone Graziosi, Sara Gualdi, Gessica Minnella, Federica Sorà, Patrizia Chiusolo, Maria Elsa Brunetti, Gennaro Napolitano, Massimo Breccia, Dimitrios Mougiakakos, Martin Böttcher, Thomas Fischer, Livia Perfetto, Francesca Sacco

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The orobasal organ (of Ackerknecht) is present in prenatal mice by Sven Schumann, Sven Schumann, Sven Schumann, Jan R. Munk, Michael J. Schmeisser, Michael J. Schmeisser, Moritz Staeber

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The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity by Jian Liu, Junli Ding, Liang Chen, Shoupeng Shao, Jie Mei, Xuejing Yang

“…Conclusions Formin-like protein 1 is a biomarker of an inflamed tumor microenvironment and positively modulates epithelial–mesenchymal transition and programmed cell death 1 ligand 1 expression in pancreatic cancer, which could be utilized as a novel target for antitumor immunity for more in-depth studies.…”
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Ferroptosis plays a role in osteoarthritis by Ruba Altahla, Jamal Alshorman, Xu Tao

“…Ferroptosis provides a new view of programmed cell death. It is initiated by the oxidation of lipids, reactive oxygen species (ROS) formation and iron buildup within cells, leading to their demise. …”
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A bibliometric analysis of research on PD-1/PD-L1 in urinary tract tumors by Yongming Chen, Xiaojin Lu, Genyuan Peng, Shengjie Liu, Miao Wang, Huimin Hou

“…Programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) are key components in immune checkpoint studies across various tumors, including those in the urinary tract. …”
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Ferroptosis determinants – potential predictors and therapeutic targets for acute myeloid leukemia by V. E. Shevchenko, T. I. Kushnir, M. V. Gudkova, N. E. Arnotskaya

“…Ferroptosis (FP) is a type of non-apoptotic programmed cell death associated with iron-dependent lipid peroxidation. …”
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Acasunlimab, an Fc-inert PD-L1×4-1BB bispecific antibody, combined with PD-1 blockade potentiates antitumor immunity via complementary immune modulatory effects by Maria Jure-Kunkel, Christina Yu, Nora Pencheva, Mark Fereshteh, Alexander Muik, Aras Toker, Özlem Türeci, Tahamtan Ahmadi, Ugur Sahin, Brandon W Higgs, Jordan M Blum, Saskia M Burm, Vanessa M Spires, Angelica Sette, Sina Fellermeier-Kopf, Andrea Imle, Michela Capello, Kristin Strumane, Theo Plantinga, Craig J Thalhauser, Kristina B Nürmberger, Patricia Garrido Castro, Carol Costa Sa, Bruna de Andrade Pereira

“…Acasunlimab (DuoBody-PD-L1×4-1BB) is an investigational, bispecific antibody designed to elicit an antitumor immune response via conditional 4-1BB activation strictly dependent on simultaneous programmed death-ligand 1 (PD-L1) binding. Since 4-1BB is coexpressed with programmed cell death protein-1 (PD-1) on CD8+ T cells, PD-1 blockade and simultaneous costimulation through 4-1BB may synergistically enhance T-cell effector functions. …”
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Progress in the study of the mechanism of ferroptosis in coronary heart disease and clinical intervention strategies by Yingzhi Liu, Zixuan Yu, Yuwen Lu, Yue Liu, Lingli Chen, Jie Li

“…Coronary heart disease (CHD), a serious cardiovascular condition with complex and diverse pathogenesis, has recently seen increased attention to the role of ferroptosis—a novel iron-dependent form of programmed cell death. This review synthesizes current research on ferroptosis mechanisms in CHD and emerging clinical intervention strategies. …”
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Research Progress in the Study of Traditional Chinese Herbal Medicine Extracts Regulating Ferroptosis thus Improving the Symptom of Alzheimer's Disease by PEI Jinying, SONG Jinzhou, MA Daofeng, LUO Xiaoting, LIU Bin, DONG Xiaohong, CONG Shuyuan

“…Ferroptosis, rising as a new research direction on AD biological mechanism in recent years, mainly studies on iron-dependent programmed cell death. A large amount of evidence has shown that AD is closely related to ferroptosis in the brain. …”
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Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: From molecular mechanisms to potential targets by Zhiyang Yin, Guanlu Shen, Minjie Fan, Pengfei Zheng

“…Ferroptosis is an iron-dependent form of programmed cell death associated with lipid peroxidation. …”
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Research progress of ferroptosis in the occurrence and development of periodontitis by SUN Ruiman, QIN Xu, ZHU Guangxun

“…Ferroptosis, an iron-dependent form of programmed cell death, is primarily characterized by altered iron homeostasis, weak antioxidant defense, and accumulation of lipid peroxides and plays an important role in a variety of diseases. …”
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Estimation of noncanonical pyroptosis biomarkers gasdermin D and caspase 4 in gingiva of periodontitis and diabetes patients: An observational cross-sectional study by Lalitha Tanjore Arunachalam, Snophia Suresh, Vamsi Lavu, Shankarram Vedamanickam, John Ebinezer, Bhavishya Balachandran

“…Pyroptosis, an inflammatory form of programmed cell death, is implicated in periodontitis and diabetes. …”
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A two-decade bibliometric analysis of tumor-associated macrophages in colorectal cancer research by Yadi Gao, Weichen Yuan, Jiexiang Zhang, Zhiwei Wang, Wenwen Cui, Zhongan Guan

“…Keyword co-occurrence and literature co-citation analysis identified nuclear factor kappa-B, endothelial growth factor, angiogenesis, polarization, TME, immune response, programmed cell death protein 1 blockade, and metabolism as current research hotspots and trends in this field. …”
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Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice. by Anna Majer, Sarah J Medina, Yulian Niu, Bernard Abrenica, Kathy J Manguiat, Kathy L Frost, Clark S Philipson, Debra L Sorensen, Stephanie A Booth

“…Our findings suggest that prion replication results in the persistent stimulation of a programmed response that is mediated, at least in part, by synaptic NMDA receptor activity that initially promotes cell survival and neurite remodelling. …”
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Alum-anchored IL-12 combined with cytotoxic chemotherapy and immune checkpoint blockade enhanced antitumor immune responses in head and neck cancer models by James W Hodge, Howard Kaufman, Michelle R Padget, Kellsye P Fabian, Sailaja Battula, Wiem Lassoued, Ginette Santiago-Sanchez, Clint Tanner Allen

“…Background First-line treatment with pembrolizumab plus chemotherapy in recurrent and metastatic head and neck squamous cell carcinomas (HNSCC) has improved survival. However, the overall response rate with this standard of care regimen (SOC) remains limited. …”
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Predictive biomarkers for targeted therapy in daily anatomic pathology for ovarian tumors by Niti Sureka, Sufian Zaheer

“…This review provides an in-depth exploration of the current and emerging predictive biomarkers in ovarian cancer, emphasizing their clinical implications and potential to improve patient outcomes.…”
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