Deciphering the tumor ecosystem dynamics undergoing immunochemotherapy therapy across multiple cancer types unveils the immunosuppressive role of S100A4 in fibroblasts by promoting... by Bo Yang, Bo Yang, Ruiji Chen, Ruiji Chen, Mali Zu, Jie Yao, Hong Ren, Hong Ren, Yingxue Lin, Yingxue Lin, Bo Zhang, Tianjiao Ji, Yang Liu

“…The data from these five cancer types underwent a rigorous process to standardize cell types across all datasets. …”
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SREBF1-mediated SND1 transcriptional activation promotes prostate cancer progression via MTDH interaction through the SESN2/AMPK/mTOR axis by Yijie Tang, Yufan Ying, Xueyou Ma, Jiahe Yi, Zixiang Liu, Yuqing Wu, Shen Lin, Xuan Shu, Zhixiang Qi, Jindan Luo, Xiangyi Zheng, Jiangfeng Li, Liping Xie, Ben Liu

“…Growing evidence indicates that Staphylococcal nuclease and Tudor domain containing 1 (SND1) is a multifunctional protein extensively involved in transcriptional regulation, RNA maturation, post-transcriptional modifications, and other processes. …”
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Effect of IL4-589C>T, FCGR2A-166His>Arg, DEFB1-20G>A, DEFB1-52G>A gene polymorphisms on TNFα, IL-1β, IL-4, and IL-10 contents in the patients with primary hip osteoarthrosis by A. M. Miromanov, T. V. Zabello, N. A. Miromanova

“…The data were statistically processed using STATISTICA 6.1 software package (StatSoft, USA), Microsoft Office Excel 2019 for Windows 10. …”
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Pragmatic clustered randomised control trial to evaluate a self-regulated learning intervention to be implemented in South Australian primary schools—study protocol by S.A Brinkman, B. Lam, S. Dawson, R. Marrone, D. Schunk, K. Winkel, H. Hermes, F. Gabriel, S. Fowler, D. Engelhardt

“…Abstract Background Self-regulated learning (SRL) is described as a process whereby learners actively take control of their learning by setting goals, planning, monitoring, evaluating, and adjusting their learning strategies to improve performance and achieve desired outcomes Panadero (Front Psychol 8:422, 2017). …”
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A New Strategy for the Treatment of Patients With Prolonged Impairment of Consciousness Using Xenon. Prospective Pilot Study by A. I. Shpichko, A. N. Kuzovlev, R. A. Cherpakov, N. P. Shpichko, O. A. Grebenchikov, A. K. Yevseyev, A. K. Shabanov, S. S. Petrikov

“…This is primarily associated with the processes of neuroinflammation, which development, according to recent data, leads to a long-term impairment of consciousness. …”
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Experimental study on freeze-thaw damage characteristics and mechanical properties of fractured rock mass of surface mine slope in cold region by Sen TIAN, Ying ZHAO, Hu SI, Chun ZHU, Quangui LI

“…The stress-strain relationship of rock masses under uniaxial compression and the trend of crack volume strain were roughly the same, which could be divided into five typical stages: the microfracture closure stage, the elastic deformation stage, the yield stage, the crack acceleration stage and the post-peak stage. The compressive strength and elastic modulus of rock masses decreased linearly with the increase of freeze-thaw cycles, while increased linearly with the increase of fracture inclination. …”
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Servizi Sociali Territoriali e Università: Esempi di Sinergie Possibili per un Percorso di Qualità by Laura Bini

“…This development does not do justice to the actual requirements of Italian society faced with ever increasing post-modern complexity which is reflected also in the nature of social problems because it implies a continuation of a faith in modernity with its idea of technical, clear-cut solutions while social relations have decidedly moved beyond that belief. …”
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Tribological properties of polymer like carbon coatings on NBG-18 nuclear graphite under nitrogen environment by HAN Hai, LIU Huichuan, CHENG Jinjuan, CHEN Xinchun, LIU Pengxiao, QI Wei, TANG Xian

“…Simultaneously, the lubrication and failure mechanisms of the PLC coatings were investigated.ResultsThe experimental results demonstrate a significant increase in the hardness of NBG-18 nuclear graphite, from 0.44 GPa to 4.16 GPa, marking an 845% improvement post-PLC coating deposition. The elastic modulus rose from 9.00 GPa to 27.21 GPa, reflecting a 202% enhancement. …”
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Reduction of the risk of bronchopleural complications after pneumonectomy due to the use of intraoperative laser treatment of the stump of the main bronchus by G. A. Asoyan, L. N. Lepekha, S. S. Sadovnikova, R. V. Tarasov, V. K. Aliev, M. A. Bagirov

“…A high percentage of cases of histological detection of an inflammatory process on the resection line is a scientifically substantiated confirmation of the need for intraoperative laser treatment of the main bronchus mucosa by the proposed method in patients with widespread destructive tuberculosis during pneumonectomy.…”
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„Ahol a kincsed, ott lesz a szíved is.” A materializmus konstruktumának vizsgálata, valamint a Materiális Értékek Skála magyar adaptációja by Andrea FERENCZI, Szabolcs TAKÁCS, Zsuzsanna KÖVI, Veronika MÉSZÁROS

“…Lastly, their content reflects post-material values that trigger socially desirable processes in the respondent that encourage consent. …”
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Implementing heart failure disease management in primary care: a mixed-methods analysis of the IMPACT-B study by Gijs Van Pottelbergh, Bert Vaes, Miek Smeets, Stefan Janssens, Willem Raat, Marie Van de Putte

“…The programme resulted in increased awareness and registration of HF in primary care, increased self-management of patients and improved follow-up after discharge, although these results should be interpreted cautiously given the uncontrolled pre-post study design.Trial registration Trial registration NCT04334447 (clinicaltrials.gov).…”
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The Palaeomeander at Vrakuňa, SW Slovakia and the historical Topography of the fording Point (Toll) on Žitný Ostrov Island / Vrakunský paleomeander a historická topografia mýtneho... by PIŠÚT, Peter, SZWARCZEWSZKI, Piotr, SMOLSKA, Ewa, RUSINKO, Adam

“…Meander was finally abandoned sometime between 1599 and 1646, possibly by an artificial cutoff. In the process, the position of toll and ferry shifted and the core of Vrakuňa with dwellings got on the right riverbank. …”
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Exosomal BMPR2 Macromolecule Facilitates Alveolar Epithelial Cell Repair Through Functional Complex Formation with BMPR1B in Acute Lung Injury by Yun X, Chen Z, Li F, Shen F, Zhang L, Yuan J

“…Emerging evidence suggests that macrophage-epithelial crosstalk plays a pivotal role in lung repair; however, the specific molecular mediators underlying this process remain largely undefined.Methods: To address this gap, we isolated and characterized macrophage-derived exosomes (MD-Exos) using dynamic light scattering, transmission electron microscopy (TEM), and immunoblotting. …”
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Investigating the mechanism of inositol against paclitaxel chemoresistance on triple-negative breast cancer by using 7T multiparametric MRI and mitochondrial changes by Wentao Xuan, Wangmin Li, Lixin Ke, Yuanyu Shen, Xiaolei Zhang, Yue Chen, Zhiliang Ye, Caiyu Zhuang, Shiyan Xie, Renhua Wu, Yan Lin

“…Inositol’s inhibition of this process makes it a potential therapy. Multiparametric MRI provides an early and effective assessment of these innovations. …”
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Sedentary Behavior and Its Association With Psychological Well-Being and Sleep Quality in Adolescents: Evidence from a Propensity Score Analysis by Zhang L, Zhao S, Zhao S, Zheng H, Ke Y, Yang W, Lei M

“…Following propensity scores matching, no significant differences in baseline characteristics were found between the two groups (All P> 0.282), indicating a successful matching process. Post-matching analysis revealed that individuals with sedentary lifestyles had significantly higher GAD-7 (P=0.002), PHQ-9 (P=0.013), and PSQI scores (P=0.001) than those without sedentary lifestyles, while no significant differences were found in SES (P=0.755) and SSRS (P=0.676).Conclusion: Our findings indicate that a sedentary lifestyle is associated with poorer psychological health and sleep quality among adolescents, even after controlling for various demographic and lifestyle factors. …”
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Análisis comparativo de los perfiles motivacionales y el Estado de Flow entre una metodología tradicional y la metodología Flipped Classroom en estudiantes de Educación Física (Co... by Pablo Cuenca Ruano, Salvador García Martínez, Alberto Ferriz Valero, Juan Tortosa Martínez

“…To observe intra-group differences (pre vs. post-test), a T-Student test was detected for related samples. …”
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Media Art—XXI Century: Genesis, Art Programs, Education Problems International Scientific Conference / Международная научно-практическая конференция «Медиаискусство XXI век. Генези... by SAZIKOV ALEXEY V. / САЗИКОВ А.В., EVALLYO VIOLETTA D. / ЭВАЛЛЬЁ В.Д.

“…It is how contemporary media, digital and post-digital technologies influence the state and development of contemporary art and art history practice, architecture, design, and decorative arts, that became the key research task of Media Art—XXI Century Conference. …”
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A Single-Chain Mpox mRNA Vaccine Elicits Protective Immune Response in Mice by Qian Xu, Rong-Rong Zhang, Mei Wu, Jie Zhang, Zu-Xin Wang, Hang Chi, Chao Zhou, Xiao-Chuan Xiong, Hai-Tao Liu, Cheng-Feng Qin, Qing Ye

“…Importantly, MPXV^eM1-eA35 demonstrated protective efficacy in a VACV challenge mouse model and showed superior capacity in preventing weight loss post-challenge compared to MPXV^eM1+eA35. …”
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Training the trainers and disseminating information: a strategy to educate health professionals on epilepsy Capacitações e multiplicadores: uma estratégia para educação de profissi... by Paula T. Fernandes, Ana L.A. Noronha, Josemir W. Sander, Gail S. Bell, Li M. Li

“…For the evaluation of this process, health professionals completed a quantitative and qualitative questionnaire to assess their knowledge, attitudes and perception (KAP) of epilepsy prior to the training (pre-test) and 6 months after it (post-test). …”
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Water footprint management in textile industry through Acid Blue 113 remediation using halloysite nanoclay as a sustainable adsorbent by Mohammed A. H. Dhaif Allah, Syed Noeman Taqui, Usman Taqui Syed, Syida Aameera Yakuth, Razia Sulthana, Rayees Afzal Mir, Akheel Ahmed Syed, Shareefraza J. Ukkund, Majed Alsubih, Saiful Islam, Wahaj Ahmad Khan

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