Transcriptome sequencing–based analysis of the molecular mechanism underlying the effect of lncRNA AC003090.1 on osteoporosis by Huafeng Zhuang, Yongjun Lin, Chengye Lin, Miao Zheng, Yizhong Li, Xuedong Yao, Youjia Xu

“…The expression levels of Runx2, Opn, and Ocn in spongy and cortical bone samples, as well as in post-infection cells, were assessed through RT-qPCR. …”
Get full text

The Impact of Earning Smoothing through Real Activities and its Components on Labor Force Investment Efficiency by Batool Ismael Hasan, Mehdi Heydari, Hamzeh Didar

“…Methods Since the results of the research can be used in the decision-making process, the present study falls within the domain of applied research, and since the data were collected based on the real information of the past, it qualifies as an ex-post facto. …”
Get full text

Resistance training as a modulator of inflammation and cognition by Jacqueline Goodrich, Jamie L. Tartar, Jonathan Banks, Francesca Leon, Jose Antonio

“…Participants n = 15 female (18.2 ± .36) untrained undergraduate students completed a baseline assessment, engaged in twice-weekly full-body resistance training, and underwent a post-training assessment. Baseline measures included cognitive performance tasks (Flanker Squared, Simon Squared, and Stroop Squared), saliva collection for IL-6, CRP, and cortisol analysis, body composition testing via InBody, a sleep quality index, and lifestyle assessment. …”
Get full text

Model for evaluating the effectiveness of the educational activities of the class teacher by V. V. Nikolina, A. A. Loshchilova, S. I. Aksenov

“…At the present stage, the institution of class leadership exists in the territory of the post-Soviet space, in China, France and a number of other countries. …”
Get full text

Antimicrobial Susceptibility Patterns of Haemophilus influenzae and Streptococcus pneumoniae in Respiratory Tract Infections: A Retrospective Observational Real-world Database Stud... by V Balaji, Vishal Singh, Puja Nijhara, Krunal Dalal, Sanket Sawant, Sebin Thomas, Lindsey Teichman, Shilpa Patkar

“…The susceptibility patterns of both organisms remained consistent during the pre- and post Coronavirus Disease-2019 (COVID-19) pandemic periods, except for H. influenzae to cefixime {94.0% (n=252) to 63.7% (n=137)}. …”
Get full text

Does initiating care in alternate care sites decrease time to disposition in the emergency department? by Alyssa Mangino, Lakshman Balaji, Bryan Stenson, Larry A. Nathanson, David Chiu, Shamai A. Grossman

“…Overall, the benefits of early initiation of care likely lie elsewhere within patient care and the ED throughput process.…”
Get full text

Predicting IDH and 1p/19q molecular status of gliomas with multi-b values DWI by Shanshan Zhao, Peipei Wang, Eryuan Gao, Mengzhu Wang, Guang Yang, Shouhui Niu, Mengjiao Pan, Kai Zhao, Jingliang Cheng, Xiaoyue Ma

“…Multi-b-value DWI images were post-processed to generate parametric maps based on the mono-exponential (Mono), the intravoxel incoherent motion (IVIM), the stretched exponential model (SEM) and the continuous-time random walk (CTRW) models. …”
Get full text

A comprehensive review and critical discussion on the application of job competency-based workshops in the domain of Traditional Chinese Medicine geriatric nursing education (岗位胜任力... by MA Junhua (马君华), GOU Huijun (苟会君), ZHENG Juan (郑娟)

“…This article reviews the current state of TCM geriatric nursing education, elucidates the concept of job competency and the workshop teaching model, and outlines its implementation process in TCM geriatric nursing instruction. Key components include curriculum design, pre-class preparation, in-class explanation, and post-class consolidation. …”
Get full text

Large Chengqi Decoction Improves Sepsis-Related Intestinal Damage by Inhibiting Inflammatory Response Through the HMGB1-TLR4 Signaling Pathway by Zhu Q, Pan Z, Li Z, Ye R, Zhuang Y, Yang M, Wang W, Pan J, Gao Q

“…Immunohistochemical analysis at 3 days post-modeling indicated that LCD1 group expressions of HMGB1, TLR4, NF-κB, and MCP-1 resembled the sham group and significantly differed from the model group. …”
Get full text

Piloting Virtual Multiple Mini Interviews (MMI) on Undergraduate Medical Students: A Multisource Feedback Analysis by Sa B, Sahu PK, Bodkyn C, Youssef F, Bethelmy A, Maharaj R, Majumder MAA

“…Utilizing technology for conducting virtual MMI is a welcomed innovation, even in the post-pandemic era. However, to optimize their effectiveness, the admission staff should refine the selection of cases, enhance the scoring system, improve time management strategies, and strengthen infrastructure and technical support.Keywords: multiple mini-interviews (MMI), feedback, online interviews, non-academic attributes, medical training…”
Get full text

Expanding the evidence on integration of cash assistance in gender-based violence case management in humanitarian settings: lessons learned from multi-country evaluations by Emily Lyles, Nancy Glass, Elisabeth Sidabutar, Erika Garcia Roa, Carlos Hoyos, Andrea Pacheco, Diana Sarria, Alice Golay, Joanna Friedman, Eleonora Argenti, Madeline Madani, Pamela Di Camillo, Giada Cicognola, Elena Bertola, Shannon Doocy

“…An evaluation of the pilots was conducted to provide a comprehensive understanding of the impacts of cash assistance within the case management process on safety, referrals and service uptake, and health. …”
Get full text

Functional Outcome of Epidural Steroid Injection in the Treatment of Chronic Low Backache due to Intervertebral Disc Prolapse by R Sahaya Jose, SL Binesh, N Kattu Bava, M Syed Moosa

“…The pre-SLR value was 61.74 ± 1.48, while the post-SLR value after 1 year of follow-up was 73.42 ± 13.36 (<i>p</i> = 0.03). …”
Get full text

Safety and User Experience of a Generative Artificial Intelligence Digital Mental Health Intervention: Exploratory Randomized Controlled Trial by Timothy R Campellone, Megan Flom, Robert M Montgomery, Lauren Bullard, Maddison C Pirner, Aaron Pavez, Michelle Morales, Devin Harper, Catherine Oddy, Tom O'Connor, Jade Daniels, Stephanie Eaneff, Valerie L Forman-Hoffman, Casey Sackett, Alison Darcy

“…Safety monitoring was conducted throughout the trial for adverse events, and the success of technical guardrails created for the generative arm was assessed post trial. ResultsIn general, the majority of measures of user relationship and experience appeared to be similar in both the generative and rules-based arms. …”
Get full text

Enhancing Neuroanatomy Teaching with DSI Studio&amp;rsquo;s Fiber Reconstruction Technology by Zeng J, Shi L, Liu Y, Yang J, Zhang L, Song H, Zhao Y, Yang J, Cheng X, Lu L

“…A total of 38 students participated in hands-on sessions, with 13 completing pre-training surveys and 19 completing post-training surveys. The students’ understanding of neuroanatomy prior to training, as well as their performance and experiences during the neuroanatomy learning process, were systematically recorded. …”
Get full text

Identification and Mechanistic Studies of Key Genes in Thalamic Hemorrhage Pain by Multi-omics by Chen Yang, Ju Gao, Yaqun Li, Yinggang Xiao, Tianfeng Huang

“…Background: Thalamic hemorrhage pain (THP), a subtype of central post-stroke pain (CPSP), commonly develops following ischemic or hemorrhagic injury to the thalamus. …”
Get full text

COVID-19 infection and its association with severe malaria & dengue: an epidemiological study from Southern India by Sara J. Ommen, Prasanna Mithra, Rekha T., Nithin Kumar, Ramesh Holla, Naveen Kulal, Mithun Rao, Bhaskaran Unnikrishnan

“…Abstract Background Post-Coronavirus Disease-19 (COVID-19) sequelae involve complex biological processes that can alter the progression and clinical outcome of other infectious diseases. …”
Get full text

Evaluation of the Proximity of the Maxillary Teeth Root Apices to the Maxillary Sinus Floor in Romanian Subjects: A Cone-Beam Computed Tomography Study by Vlad Ionuţ Iliescu, Vanda Roxana Nimigean, Cristina Teodora Preoteasa, Lavinia Georgescu, Victor Nimigean

“…Nonparametric tests were used for statistical analysis, and multiple comparisons were performed using Bonferroni post hoc correction. <b>Results</b>: The study included 70 individuals aged 20 to 60 years. …”
Get full text

Serum Pharmacochemistry and Network Pharmacology Reveal Active Compounds and Mechanisms of the Huaxian Formula in Alleviating Radiation-Induced Pulmonary Fibrosis by Gong C, Chen J, Zou P, Fang Z, Quan L, Wang J, Yin J, Lin B, Lang J, Chen M

“…Finally, animal experiments confirmed that HXF significantly inhibited the expression of p-Akt and p-PI3K proteins in the lung tissue of irradiated mice.Conclusion: Our research results indicate that HXF may exert its effects on the prevention and treatment of radiation-induced pulmonary fibrosis (RIPF) through multiple pathways and targets, with the PI3K-Akt signaling pathway likely playing the most crucial role in this process. Keywords: radiation-induced pulmonary fibrosis, Huaxian formula, serum pharmacochemistry, network pharmacology, active compounds…”
Get full text

Insights into potential of banana leaf powder as a mud soil stabilizer by Amulie Jarjusey, Kimitoshi Hayano, Alula Araya Kassa, Shovon Raihan, Yoshitoshi Mochizuki

“…These results suggest that differences in the stabilizer's water absorption mechanism affect the effectiveness of the post-treatment compaction process on the treated soil. …”
Get full text

Novel Classification of Peroneal Tendon Disease Reveals Cellular and Molecular Phenotypes of the Tenosvnovium by Julia Matthias MD, Michael A. David PhD, Sara E. Buckley DO, Daniel J. Ross MD, Nathaniel Zona BA, Michael A. Hewitt B.A., Joshua Metzl MD, Daniel K. Moon MD, MS, MBA, Courtney Grimsrud MD, Douglas J. Adams PhD, Michael Zuscik PhD, Kenneth Hunt MD

“…Kruskal Wallis with Dunn’s post-hoc was used to detect differences in cellular density between PTD1-4 vs PTD0. …”
Get full text