Research progress on molecular markers for diagnosing VTE in orthopedic surgery patients by Zhengsheng Wu, Biqin Zhang, Qian Xu, Yi Zhang, Jianan Zhu, Bingyu Chen, Yaoqiang Du

“…Additional thrombotic markers, such as thrombin-antithrombin complex (TAT), plasmin-α2-plasmin inhibitor complex (PIC), tissue plasminogen activator inhibitor complex (t-PAIC), and thrombomodulin (TM), are produced at the initial stages of thrombotic response and allow for a more sensitive and comprehensive evaluation of thrombosis development, thrombolytic efficacy, post-procedural thrombosis and hemorrhage, and vascular endothelial damage. …”
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Arginine-Mediated Liver Immune Regulation and Antioxidant Defense in Largemouth Bass (<i>Micropterus salmoides</i>): Multi-Omics Insights into Metabolic Remodeling During <i>Nocard... by Yu-Long Sun, Shuai-Liang Zhang, Feng-Feng Zhou, Yuan-Xin Qian, Yang He, Run-Zhe Zhang, Fen Dong, Qiang Chen, Han-Ying Xu, Ji-Teng Wang, Yu-Ting Deng, Tao Han

“…To further elucidate the regulatory effects of arginine on the immune and antioxidant processes in the liver, primary hepatocytes were isolated and cultured. …”
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Donor lung weight a novel predictor for primary graft dysfunction by Andreas Martinsson, MD, Anders Thoren, MD, PhD, Sven-Erik Ricksten, MD, PhD, Jonatan Oras, MD, PhD, Moustafa Mohsen Abed, MD, Petra Vestlund, CTC, Jesper M. Magnusson, MD, PhD, Andreas Wallinder, MD, PhD

“…Pre-existing injury and stress during the donation process are further aggravated by ischemia-reperfusion injury occurring during donation and transplantation. …”
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System for delivering microwave ablation to subcutaneous tumors in small-animals under high-field MRI thermometry guidance by Jan Sebek, Tej B. Shrestha, Matthew T. Basel, Faraz Chamani, Nooshin Zeinali, Ivina Mali, Macy Payne, Sarah A. Timmerman, Pegah Faridi, Marla Pyle, Martin O’Halloran, M. Conall Dennedy, Stefan H. Bossmann, Punit Prakash

“…HAC15 tumors implanted in nude mice (n = 6) were ablated in vivo and monitored with MRIT in multiple planes. One day post ablation, animals were euthanized, and excised tumors were processed for viability assessment.Results Average absolute error between temperatures from fiberoptic sensors and MRIT was 0.6 °C across all ex-vivo ablations. …”
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Application of granular and ozone-biological activated carbon treatments for the mitigation of organic chemical peaking events in potable water schemes by George William Kajjumba, Ceonie M.M. Washington, Aarthi Mohan, Zita L.T. Yu, Larry Schimmoller, Jesus Gonzalez, R. Scott Summers, Eric R.V. Dickenson

“…Direct potable reuse employing reverse osmosis (RO) and advanced oxidation processes (AOP) is emerging as a solution to combat water scarcity in many communities. …”
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The Petrology and Geochemistry of the 2021 Fagradalsfjall Eruption, Iceland: An Eruption Sourced From Multiple, Compositionally Diverse, Near‐Moho Sills by E. W. Marshall, A. Caracciolo, E. Bali, S. A. Halldórsson, S. Matthews, E. Ranta, M. B. Rasmussen, J. G. Robin, G. H. Guðfinnson, J. Maclennan, C. Bosq, D. Auclair, O. Sigmarsson, H. Merrill, B. Gísladóttir, S. Johnson, N. Löw, A. Stracke, F. Genske

“…Abstract Magmatic processes at the crust‐mantle boundary (i.e., Moho) are commonly studied post facto at fossil ophiolites, oceanic core complexes, or inferred from the compositions of crystals or melt inclusions. …”
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Oceanographic Characteristics in the Three International Indonesian Archipelago Sea Lanes (IASLs) Region: Implications for Underwater Acoustics System by I Wayan Sumardana Eka Putra, Agus Saleh Atmadipoera, Henry Munandar Manik, Gentio Harsono, Adi Purwandana

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Feasibility of whole‐body MRI for cancer screening in children and young people with ataxia telangiectasia: A mixed methods cross‐sectional study by Renata Neves, Rafal Panek, Katie Clarkson, Ouliana Panagioti, Natasha Schneider Fernandez, Sophie Wilne, Mohnish Suri, William P. Whitehouse, Sumit Jagani, Madhumita Dandapani, Cris Glazebrook, Robert A. Dineen

“…Positive imaging findings were classified according to the ONCO‐RADS system. Post‐participation interviews were performed with recruited families to assess the experience of participating and feelings about waiting for, and communication of, the findings of the scan. …”
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MiRNA expression affects survival in patients with obstructive sleep apnea and metastatic colorectal cancer by Piera Soccio, Giorgia Moriondo, Giulia Scioscia, Pasquale Tondo, Giuseppina Bruno, Guido Giordano, Roberto Sabato, Maria Pia Foschino Barbaro, Matteo Landriscina, Donato Lacedonia

“…In the last few years, research has focused on the exploration of different biomarkers to understand the mechanisms underlying this relationship and miRNAs, non-coding single strands of about 22 nucleotides that post-transcriptionally regulate gene expression, have emerged as possible actors of this process.The aim of the study was to evaluate the impact of OSA on survival of metastatic colorectal cancer (mCRC) patients based on the expression of specific miRNAs. …”
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Influence of nutrition with leachate based on compost from vegetable waste on the physical, chemical, and biological characteristics of radish (Raphanus sativus L.) by D. D. Cruz Nieto, N. E. Muguruza Crispín, E. T. Castañeda Chirre, J. U. Romero Menacho, J. V. Nunja García, M. C. Saucedo López, J. C. Cabanillas Sulca, C. P. Alvarez Quinteros, C. F. Goñy Ameri, C. M. Caira Mamani, M. N. Morales Alberto, G. P. Lacherre Rodriguez, M. V. Bautista Espinoza, G. C. Pesantes Arriola, J. R. Reaño Rivera, A. M. Contreras Vargas

“…Abstract The economic instability in Peru was influenced by the post-pandemic period, the war between Russia and Ukraine, and the geopolitical confrontation between the United States and China, which caused an increase in fertilizer prices. …”
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Construction and validation of a clinical prediction model for sepsis using peripheral perfusion index to predict in-hospital and 28-day mortality risk by Qirui Guo, Wenbo Li, Jie Wang, Guangjian Wang, Qingyu Deng, Hui Lian, Xiaoting Wang

“…The pathophysiological process of sepsis is related to the body’s dysregulated response to infection, with microcirculatory changes serving as early warning signals that guide clinical treatment. …”
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Low Ventricular Stiffness Is Associated With Suboptimal Outcomes in Patients With a Single Right Ventricle After the Fontan Operation: A Novel Phenotype by Shahryar M. Chowdhury, Andrew M. Atz, Eric M. Graham, Varsha M. Bandisode, John F. Rhodes, Arni C. Nutting, Carolyn Taylor, Andrew Savage, Marc Hassid, Minoo Kavarana, Donald Menick

“…Background Despite a rigorous screening process, including cardiac catheterization, a subset of patients with a single right ventricle (SRV) demonstrates suboptimal short‐term outcomes after the Fontan operation. …”
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Macrophage mannose receptor CD206-targeted PET imaging in experimental acute myocardial infarction by Putri Andriana, Senthil Palani, Heidi Liljenbäck, Imran Iqbal, Vesa Oikonen, Jenni Virta, Konstantina Makrypidi, Johan Rajander, Erika Atencio Herre, Aino Suni, Sirpa Jalkanen, Juhani Knuuti, Luisa Martinez-Pomares, Ioannis Pirmettis, Xiang-Guo Li, Antti Saraste, Anne Roivainen

“…Conclusion Al[18F]F-NOTA-D10CM PET detects overexpression of CD206 after ischemic myocardial injury, and may be a suitable biomarker for detecting M2-type macrophages associated with the inflammatory process post-MI. Graphical abstract…”
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The epididymal microenvironment in Akodon cursor (Muridae, Sigmodontinae, Akodontini): The lifetime of spermatozoa from production to maturation by Tatiana Prata Menezes, Fernanda Carolina Ribeiro Dias, Nara Clara Lazaroni e Merchid, Camila Folly Batista, Camilo Jose Ramirez-Lopez, Arabela Guedes de Azevedo Viana, Renner Philipe Rodrigues Carvalho, Adrielli Ribeiro Araújo, José Lino-Neto, Gisele Lessa, Arlindo A. Moura, Mariana Machado-Neves

“…The epididymides were processed for histological, functional, and proteomic analyses, besides sperm quality evaluation. …”
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Effects of a closed-loop mindfulness-based program for reducing stress in family caregivers of people with dementia: a study protocol of a randomized controlled trial by Patrick Pui Kin Kor, Kee Lee Chou, Alex Pak Lik Tsang, Winnie W. S. Mak, Julieta Galante, Rainbow Tin Hung Ho, Samuel Yeung Shan Wong, Daphne Sze Ki Cheung, Justina Yat Wa Liu, Steven H. Zarit

“…A process evaluation will examine whether dispositional mindfulness mediates the relationship between mobile app usage and stress reduction. …”
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Statistics and behavior of clinically significant extra-pulmonary vein atrial fibrillation sources: machine-learning-enhanced electrographic flow mapping in persistent atrial fibri... by Peter Ruppersberg, Steven Castellano, Philip Haeusser, Kostiantyn Ahapov, Melissa H. Kong, Stefan G. Spitzer, Stefan G. Spitzer, Georg Nölker, Andreas Rillig, Tamas Szili-Torok

“…Significant sources persisting post-procedure were associated with significantly higher recurrence rates than those successfully ablated. …”
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Sub-lethal stress-induced cross-protection against ultraviolet-C in Salmonella enterica on raw whole almonds and fresh-cut leafy greens by Zhao Chen, Zhao Chen, Jie Zheng, Shirley A. Micallef, Shirley A. Micallef, Jianghong Meng, Jianghong Meng, Jianghong Meng

“…Additionally, we assessed the survival of sub-lethally stressed cells on FCLGs under cold or temperature abuse condition post-UV-C treatment. A cocktail of three S. enterica strains, along with S. …”
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FCGR1A Alleviates Ischemic Stroke-induced Injury by Promoting Anti-Inflammatory Microglial Polarization via the AMPK–mTOR Signaling Pathway by Meng Liu, Xuhui Fan, Dongya Chen, Huibin Yao, Zhihui Huang, Heng Li, Qing Zhang, Yuqi Wang, Haihan Song, Yufeng Yan

“…Background: Ischemic stroke triggers inflammatory responses that lead to neuronal damage, with microglial polarization significantly influencing post-stroke inflammation. This study explores the role of Fc gamma receptor Ia (FCGR1A) in microglial polarization and its regulatory mechanisms in ischemic stroke. …”
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Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib by Chiara Bellocchi, Ennio Giulio Favalli, Gabriella Maioli, Elena Agape, Marzia Rossato, Matteo Paini, Adriana Severino, Barbara Vigone, Martina Biggioggero, Elena Trombetta, Roberto Caporali, Lorenzo Beretta

“…Linear models were used to determine differentially expressed genes (DEGs) (1) at baseline according to clinical responses and (2) in the pre‐post comparison after tofacitinib treatment and in relation to EULAR responses. …”
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Impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients: a prospective cohort study by Ahmad Khan, Saima Mushtaq, Amjad Khan, Nafees Ahmad, Shahzadi Sidra Saleem, Rubina Aman, Shahzadi Sadia Saleem, Ayesha Bibi, Saifullah Mehsud, Ivan R Green, Sheikh Abdur Rashid, Kifayat Ullah Shah

“…This study aims to assess the impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients.Design A pre–post cohort study.Setting Outpatient department of a tertiary care hospital affiliated with Quaid-i-Azam University, Pakistan.Participants Approximately 265 adult asthmatic patients selected through a spirometry process, aged ≥18 years, were approached. 240 patients gave consent to participate in the study and were divided into control and treatment groups.Interventions The educational intervention consisted of individual patient counselling using educational material with time varied according to each patient’s comprehension and previous knowledge.Primary and secondary outcome measures Assessment consisted of a 14-item Asthma Self-Management Knowledge Questionnaire (ASMQ) quantifying a patient’s self-management knowledge through an ASMQ score and its change following an educational intervention.Results Disease self-management knowledge was low with an average raw ASMQ score of 4.1 (max 14); which equates to a transformed score of 29.34 (max 100) and the proportion of patients who correctly answered more than 50% of questions were 16.7% preintervention. …”
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