SLOWING THE GROWTH OF AN AGGRESSIVE GLIOBLASTOMA CELL LINE BY ENHANCER RNA SILENCING DEPENDS ON THE KNOCKDOWN METHOD by Ekaterina Statsevich, Anastasiia Simonova, Anastasiya Poteryakhina, Uliana Beri, Elvina Bogomolova, Aksinya Uvarova, Matvey Murashko, Elina Zheremyan, Kirill Korneev, Dmitry Kuprash, Denis Demin

“…Compared to the previously studied cell line DBTRG-05MG, the U-251 cell line is more aggressive, has a higher proliferation rate and was derived from patient tissue at a later stage of the disease. …”
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«DELTA-VAC» SUBUNIT VACCINE INDUCES STRONG HUMORAL IMMUNE RESPONSE AGAINST SARS-COV-2 by Valentina Sergeevna Nesmeyanova, Yuliya Aleksandrovna Merkulyeva, Anastasiya Aleksandrovna Isaeva, Natalya Vyacheslavovna Volkova, Svetlana Valeryena Belenkaya, Mariya Borisovna Borgoyakova, Ekaterina Alexandrovna Volosnikova, Tatiana Igorevna Esina, Elena Dmitrievna Danilenko, Anna Vladimirovna Zaikovskaya, Sergey Evgenievich Olkin, Oleg Viktorovich Pyankov, Aleksandr Alekseevich Ilichev, Dmitriy Nikolaevich Shcherbakov

“…However, the safety of these vaccines is often associated with low effectiveness, so it is often necessary to use adjuvants, as well as use more complex immunization regimens. At the same time, an important advantage of subunit vaccines is scalability and relative ease of production, since there is no need to work with live virus or viral vectors during the production process. …”
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Analysing gender disparities in youth sports coaching: an international survey (FEMCoach project) by Vanessa Dias, Julio Calleja-Gonzalez, Víctor López-Ros, Raquel Font-Lladó, Jorge Arede, Leonardo Cunha, Stella Douka, Bruno Rosa, Graça Pinto, Graça Pinto, Nuno Leite, Nuno Leite

“…Considering the presence of topics related to female biology in coaches' education process the majority of women [72% (±5%)] and men [63% (±5%)] considered that they were not approached enough, agreeing most of the coaches, women [92% (±3%)] and men [87% (±4%)], that coach education programmes should be more expanded to cover it. …”
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Immunonutrition in ERAS Protocol for Patients with Gynecologic Cancer: A Narrative Review of the Literature by Vasilios Lygizos, Dimitrios Haidopoulos, Dimitrios Efthymios Vlachos, Antonia Varthaliti, Maria Fanaki, George Daskalakis, Nikolaos Thomakos, Vasilios Pergialiotis

“…At the time of the surgeries, due to their wide scope and aggressive treatments such as chemotherapy and radiotherapy, the situation becomes more serious. Those micronutrients taking part in immunonutrition, namely, arginine, omega-3 fatty acids, nucleotides, and antioxidants, have the potential to prevent inflammation, protect against infections, and promote healing after the surgery. …”
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Essential genes encoded by the mating-type locus of the human fungal pathogen Cryptococcus neoformans by Zhuyun Bian, Ziyan Xu, Anushka Peer, Yeseul Choi, Shelby J. Priest, Konstantina Akritidou, Ananya Dasgupta, Tim A. Dahlmann, Ulrich Kück, Minou Nowrousian, Matthew S. Sachs, Sheng Sun, Joseph Heitman

“…In contrast to a majority of species in the phylum Basidiomycota that have tetrapolar mating-type systems, the opportunistic human pathogen Cryptococcus neoformans employs a bipolar mating-type system, with two mating types (a and α) determined by a single MAT locus that is unusually large (~120 kb) and contains more than 20 genes. While several MAT genes are associated with mating and sexual development, others control conserved cellular processes (e.g., cargo transport and protein synthesis), of which five (MYO2, PRT1, RPL22, RPL39, and RPO41) have been hypothesized to be essential. …”
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MRI study of medial meniscus degeneration of osteoarthritic knees with or without posterior root tear by Kosuke Hisashi, Takeshi Muneta, Yuji Kohno, Mana Sasaki, Junya Yamazaki, Haruhisa Hayashi, Hideyuki Koga, Toshiyuki Morito

“…Following the exclusion process, 151 knees were selected for MRI analysis. …”
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The Phytochemical Profile and Antioxidant and Gastroprotective Effects of Three Varieties of <i>Chenopodium quinoa</i> Willd. Sprouts Cultivated in Peru by Edwin Carlos Enciso-Roca, Jorge Luis Arroyo-Acevedo, Pablo Williams Común-Ventura, Johnny Aldo Tinco-Jayo, Enrique Javier Aguilar-Felices, Mahomi Bertha Ramos-Meneses, Rosa Elizabeth Carrera-Palao, Oscar Herrera-Calderon

“…The pasankalla quinoa exhibits more significant antioxidant activity and a stronger gastroprotective effect compared to the other varieties examined in this study. …”
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Predicting climate-driven shift of the East Mediterranean endemic Cynara cornigera Lindl by Heba Bedair, Heba Bedair, Yehia Hazzazi, Asmaa Abo Hatab, Marwa Waseem A. Halmy, Mohammed A. Dakhil, Mohammed A. Dakhil, Mubaraka S. Alghariani, Mubaraka S. Alghariani, Mari Sumayli, A. El-Shabasy, Mohamed M. El-Khalafy

“…Furthermore, our models predicted that the distribution range of C. cornigera would drop by more than 25% during the next few decades. Surprisingly, the future potential distribution area of C. cornigera (SSP 126 scenario) for 2061 and 2080 showed that there is increase in the suitable habitats area. …”
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Scalable synthesis of NiFe-layered double hydroxide for efficient anion exchange membrane electrolysis by Alvaro Seijas-Da Silva, Adrian Hartert, Víctor Oestreicher, Jorge Romero, Camilo Jaramillo-Hernández, Luuk J. J. Muris, Grégoire Thorez, Bruno J. C. Vieira, Guillaume Ducourthial, Alice Fiocco, Sébastien Legendre, Cristián Huck-Iriart, Martín Mizrahi, Diego López-Alcalá, Anna T. S. Freiberg, Karl J. J. Mayrhofer, João C. Waerenborgh, José J. Baldoví, Serhiy Cherevko, Maria Varela, Simon Thiele, Vicent Lloret, Gonzalo Abellán

“…This scalable approach could considerably lower the cost of green hydrogen production by enabling more efficient alkaline electrolyzers.…”
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Full lifecycle carbon emissions accounting and regional environmental impact assessment of typical open-pit coal mines by Mingqi LIU, Xiaoping ZHANG, Yu WANG, Zhipeng YANG, Xinhong YU, Agudamu HU, Guoqing YANG, Ying ZHU, Yingnan CAO, Wei LIU, Tianlong ZHENG, Yaoqiang HUO, Jianguo LIU

“…At the same time, according to the current mining methods and processes, the country will generate more than 2.3 billion yuan of additional economic expenditure every year, and with the increase in open-pit coal mining, it will increase year by year. …”
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Applying design to design: demonstrating how to create a human-centered design session interview guide for use with adolescents by Macarena Kruger, Macarena Kruger, Andrea B. Goldschmidt, Adrian Ortega, Adrian Ortega, Abigail Wharton, Danielle A. N. Chapa, Erin R. Stalvey, Isabel R. Rooper, Isabel R. Rooper, Katrina T. Obleada, Katrina T. Obleada, Graham C. Miller, Graham C. Miller, Andrea K. Graham, Andrea K. Graham

“…., future users of the DHI) into iterative design processes, thereby prioritizing their needs and preferences. …”
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Variation within and between digital pathology and light microscopy for the diagnosis of histopathology slides: blinded crossover comparison study by David RJ Snead, Ayesha S Azam, Jenny Thirlwall, Peter Kimani, Louise Hiller, Adam Bickers, Clinton Boyd, David Boyle, David Clark, Ian Ellis, Kishore Gopalakrishnan, Mohammad Ilyas, Paul Kelly, Maurice Loughrey, Desley Neil, Emad Rakha, Ian SD Roberts, Shatrughan Sah, Maria Soares, YeeWah Tsang, Manuel Salto-Tellez, Helen Higgins, Donna Howe, Abigail Takyi, Yan Chen, Agnieszka Ignatowicz, Jason Madan, Henry Nwankwo, George Partridge, Janet Dunn

“…Digital pathology is a process of converting microscope slides to computer image files. …”
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Effects of pharmacological and non-pharmacological interventions for the management of sleep problems in people with fibromyalgia: a multi-methods evidence synthesis by Mari Imamura, Clare Robertson, Jemma Hudson, Daniel Whibley, Lorna Aucott, Katie Gillies, Marcus Beasley, Martin J Stevens, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole KY Tang, Gary J Macfarlane, Miriam Brazzelli

“…Future work High-quality research is needed to investigate which interventions are more likely to be effective for treating fibromyalgia-related sleep problems. …”
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Medical Assistance in Dying for Persons Suffering Solely from Mental Illness in Canada by Chloe Eunice Panganiban, Srushhti Trivedi

“… [31] Steven, “Number of Assisted Deaths Jumped More than 30 per Cent in 2022, Report Says | CBC News…”
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Tuberculosis infection control in MDR-TB designated hospitals in Jiangsu Province, China by Honghuan Song, Guoli Li, Zhuping Xu, Feixian Wang, Xiaoping Wang, Bing Dai, Xing Zhang, Jincheng Li, Yan Li, Limei Zhu

“…Subsequent monitoring was conducted quarterly, with corrective actions accordingly. More than two years of follow-up data were collected, with the collaboration of local hospitals, the municipality Centers for Disease Control and Prevention (CDC), and the Jiangsu Provincial CDC, concluding on August 31, 2021. …”
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Assessing the Impact on Electronic Health Record Burden After Five Years of Physician Engagement in a Canadian Mental Health Organization: Mixed-Methods Study by Tania Tajirian, Brian Lo, Gillian Strudwick, Adam Tasca, Emily Kendell, Brittany Poynter, Sanjeev Kumar, Po-Yen (Brian) Chang, Candice Kung, Debbie Schachter, Gwyneth Zai, Michael Kiang, Tamara Hoppe, Sara Ling, Uzma Haider, Kavini Rabel, Noelle Coombe, Damian Jankowicz, Sanjeev Sockalingam

“…Regarding the physician engagement strategy initiatives, 39% (50/128) agreed that communication through the strategy is efficient, and 75% (96/128) felt more proficient in using the EHR. However, additional areas for improvement within the EHR were identified, including (1) medication reconciliation and prescription processes; (2) chart navigation and information retrieval; (3) longitudinal medication history; and (4) technology infrastructure challenges. …”
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PBMC transcriptome changes in beef steers with negative or positive residual feed intake following in vitro LPS stimulation by Yarahy Leal, Samanthia Johnson, Modoluwamu Idowu, Godstime Taiwo, Taylor Sidney, Emily Treon, Deborah Ologunagba, Luke M. Gratz, Olanrewaju B. Morenikeji, Ibukun M. Ogunade

“…Taken together, these findings suggest that negative-RFI beef steers may possess a more competent and energy-conserving immune response, marked by a quicker resolution of inflammation and a balanced pro- and anti-inflammatory response. …”
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Live Birth Resulting from the Direct Warming and Direct Rehydration of Vitrified Human Blastocyst in Embryo Culture Medium: A Pilot Study by David Yiu Leung Chan, Murong Xu, Waner Wu, Ka Kei Fung, Linyao Zhang, Hoi Ming Wan, Carol Pui Shan Chan, Jacqueline Pui Wah Chung

“…Background: Frozen embryo transfer (FET) has been a routine assisted reproductive technology (ART) procedure since the first FET by slow freezing. It is estimated that more than 2 million FET cycles are performed worldwide each year. …”
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The ZiCOS-M CO₂ sensor network: measurement performance and CO₂ variability across Zurich by S. K. Grange, S. K. Grange, S. K. Grange, P. Rubli, A. Fischer, D. Brunner, C. Hueglin, L. Emmenegger

“…High-<span class="inline-formula">CO₂</span> episodes were detected outside Zurich's urban area, demonstrating that processes acting on a variety of scales drove <span class="inline-formula">CO₂</span> levels. …”
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Chemical magnetic field-assisted batch polishing method of 316L stainless steel by Fukang Yin, Chenchun Shi, Zikang Huang, Ke Wu, Jinbang Li, Chunjin Wang

“…Nonetheless, material removal rate reached to the maximum, which could be around 168% more than that after MABP, when pH and H2O2 concentration were determined as 3.0 and 2.0 wt%, respectively. …”
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