Interventions to improve mental health and well-being in care-experienced children and young people aged less than 25: the CHIMES systematic review by Rhiannon Evans, Sarah MacDonald, Robert Trubey, Jane Noyes, Michael Robling, Simone Willis, Soo Vinnicombe, Maria Boffey, Charlotte Wooders, Asmaa El-Banna, GJ Melendez-Torres

“…This is in contrast to a more comprehensive, if equivocal, evidence base internationally, particularly in the USA. …”
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Core to Cosmic Edge: <tt>SIMBA-C</tt>’s New Take on Abundance Profiles in the Intragroup Medium at <i>z</i> = 0 by Aviv Padawer-Blatt, Zhiwei Shao, Renier T. Hough, Douglas Rennehan, Ruxin Barré, Vida Saeedzadeh, Arif Babul, Romeel Davé, Chiaki Kobayashi, Weiguang Cui, François Mernier, Ghassem Gozaliasl

“…Our study suggests that a more realistic chemical enrichment model broadly improves agreement with observations, but physically motivated sub-grid models for other key processes, like AGN and stellar feedback and turbulent diffusion, are required to realistically reproduce observed group environments.…”
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The influence of the ratio of liver cells and bone marrow in the implantable cell-engineering structures of the liver on the recovery efficiency of functional and morphological par... by M. Yu. Shagidulin, N. A. Onishchenko, M. E. Krasheninnikov, A. O. Nikolskaya, E. A. Volkova, I. M. Iljinsky, N. P. Mogeiko, V. I. Sevastianov, S. V. Gautier

“…The effectiveness of the regulatory effects of CECs (with different cell ratios) on regenerative processes in livers were assessed by using biochemical, morphological and morphometric methods at different periods after their implantation.Results. …”
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The Practical, Robust Implementation and Sustainability (PRISM)-capabilities model for use of Artificial Intelligence in community-engaged implementation science research by Nabila El-Bassel, James David, Trena I. Mukherjee, Maneesha Aggarwal, Elwin Wu, Louisa Gilbert, Scott Walters, Redonna Chandler, Tim Hunt, Victoria Frye, Aimee Campbell, Dawn A. Goddard-Eckrich, Katherine Keyes, Shoshana N. Benjamin, Raymond Balise, Smaranda Muresan, Eric Aragundi, Marc Chen, Parixit Davé, David Lounsbury, Nasim Sabounchi, Dan Feaster, Terry Huang, Tian Zheng

“…Artificial Intelligence (AI) could enhance the collaborative process by improving data collection, analysis, insight, and engagement, while preserving research ethics. …”
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Airway microbiota dysbiosis and metabolic disorder in ozone and PM2.5 co-exposure induced lung inflammatory injury in mice by Lin Yang, Fei Xu, Shuaiqi Zhao, Yuling Zeng, Qiong Wu, Ling Zhang, Saige Shi, Fengquan Zhang, Juan Li, Zhen An, Huijun Li, Hui Wu, Jie Song, Weidong Wu

“…Further studies revealed that co-exposure to O3 and PM2.5 increased the abundance of Prevotella in the airways and caused more severe metabolic disorders compared to O3 or PM2.5 exposure. …”
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Walnut Shell as a bio-activated carbon for elimination of malachite green from its aqueous solution: Adsorption isotherms, kinetics and thermodynamic studies by Lekaa Hussein Abid, Zainab Haider Mussa, Issa Farhan Deyab, Lubna Raad Al-Ameer, Haider Falih Shamikh Al-Saedi, Fouad Fadhil Al-Qaim, Hesam Kamyab, Saravanan Rajendran, Ahmed Falah Imran, Zaher Mundher Yaseen

“…The equilibrium adsorption data fit the Langmuir equation more closely, as evidenced by a high correlation factor (R2 = 0.9970). …”
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Symptom-specific gut microbial and metabolic profiles in ADHD reveal SCFA deficiency as a Key pathogenic mechanism by Xinyue Wang, Ning Wang, Teng Gao, Yunfan Zhang, Zhao Fu, Yilu Zhao, Yujingwen Huang, Xiangyu Zheng, Xuping Gao, Lin Lu, Li Yang

“…Fecal microbiota transplantation in mice validated the hypothesis that gut microbial composition affects ADHD symptoms through metabolic alterations. This study provides more insight into the mechanisms underlying metabolic disturbances in ADHD and elucidates the role of gut microbiota in these processes.…”
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Gestational diabetes-combined excess weight gain exacerbates gut microbiota dysbiosis in newborns, associated with reduced abundance of Clostridium, Coriobacteriaceae, and Collinse... by Yunshan Xiao, Yunshan Xiao, Yunshan Xiao, Yuan Shi, Yuan Shi, Yuan Shi, Yan Ni, Meilan Ni, Yuxin Yang, Xueqin Zhang, Xueqin Zhang, Xueqin Zhang

“…Further,LEfSe analysis identified 30 differential bacteria taxa between GDM-Total and healthy control groups, which increased to 38 between GDM+EGWG and non-GDM groups, highlighting more pronounced microbial shifts associated with EGWG. …”
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CHIVID: A Rapid Deployment of Community and Home Isolation During COVID-19 Pandemics by Parpada Piamjinda, Chiraphat Boonnag, Piyalitt Ittichaiwong, Seandee Rattanasonrerk, Kanyakorn Veerakanjana, Khanita Duangchaemkarn, Warissara Limpornchitwilai, Kamonwan Thanontip, Napasara Asawalertsak, Thitikorn Kaewlee, Theerawit Wilaiprasitporn

“…Results: Approximately 71.4&#x0025; of healthcare practitioners use the system more than twice daily, with the majority managing 1&#x2013;10 patients, while 11.4&#x0025; handle over 101 patients. …”
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ASURA-FDPS-ML: Star-by-star Galaxy Simulations Accelerated by Surrogate Modeling for Supernova Feedback by Keiya Hirashima, Kana Moriwaki, Michiko S. Fujii, Yutaka Hirai, Takayuki R. Saitoh, Junichiro Makino, Ulrich P. Steinwandel, Shirley Ho

“…Massive stars with a zero-age main-sequence mass of more than about 10 M _⊙ explode as core-collapse supernovae (CCSNe), which play a critical role in galaxy formation. …”
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Impact of lower hybrid wave injection on edge localized modes in the HL-3 tokamak by Y.M. Zhang, S.Y. Chen, N. Wu, X.Y. Bai, G.L. Xiao, Y.R. Zhu, Y. Zhou, X.X. He, W.P. Guo, F. Zhang, M.L. Mou, T.Q. Liu, N. Yang, X. Lu, T.Y. Wang, A.S. Liang, Z.B. Shi, C.J. Tang, W.L. Zhong

“…The experiments and simulations carried out in the HL-3 tokamak significantly contribute to a more profound and comprehensive understanding of the physical mechanisms of ELMs control with LHW injection.…”
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Sequencing Silicates in the Spitzer Infrared Spectrograph Debris Disk Catalog. I. Methodology for Unsupervised Clustering by Cicero X. Lu, Tushar Mittal, Christine H. Chen, Alexis Y. Li, Kadin Worthen, B. A. Sargent, Carey M. Lisse, G. C. Sloan, Dean C. Hines, Dan M. Watson, Isabel Rebollido, Bin B. Ren, Joel D. Green

“…This paper details the methodology, implementation, and initial results of CLUES , setting the stage for more detailed follow-up studies focusing on debris disk mineralogy and demographics.…”
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Interplay between tumor mutation burden and the tumor microenvironment predicts the prognosis of pan-cancer anti-PD-1/PD-L1 therapy by Wuyuan Liao, Wuyuan Liao, Wuyuan Liao, Xinwei Zhou, Xinwei Zhou, Hansen Lin, Hansen Lin, Zihao Feng, Zihao Feng, Xinyan Chen, Yuhang Chen, Yuhang Chen, Minyu Chen, Minyu Chen, Mingjie Lin, Mingjie Lin, Gaosheng Yao, Gaosheng Yao, Jinwei Chen, Jinwei Chen, Haoqian Feng, Haoqian Feng, Yinghan Wang, Yinghan Wang, Zhiping Tan, Zhiping Tan, Youyan Tan, Jun Lu, Jun Lu, Pengju Li, Pengju Li, Jinhuan Wei, Jinhuan Wei, Li Luo, Li Luo, Liangmin Fu, Liangmin Fu, Liangmin Fu

“…Future research should focus on further validating this model in larger and more diverse cohorts, refining the gene set selection process, and exploring the specific mechanisms through which the identified biomarkers influence the TME and treatment response.…”
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Response of the nosZ-type denitrifying microbial community and metabolic characteristics to precipitation changes in the alpine wetland by Ni Zhang, Ni Zhang, Ni Zhang, Hongchen Jiang, Hongchen Jiang, Zhiyun Zhou, Zhiyun Zhou, Zhiyun Zhou, Yijun Wang, Desheng Qi, Desheng Qi, Desheng Qi, Shijia Zhou, Shijia Zhou, Shijia Zhou, Jing Ma, Jing Ma, Jing Ma, Kelong Chen, Kelong Chen, Kelong Chen

“…In summary, lower precipitation is more favorable for maintaining carbon storage in the source wetlands of Qinghai Lake. …”
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Clinical Subtype Trajectories in Sepsis Patients Admitted to the ICU: A Secondary Analysis of an Observational Study by Marleen A. Slim, MD, Rombout B. E. van Amstel, MD, Marcella C.A. Müller, MD, PhD, Olaf L. Cremer, MD, PhD, Alexander P. J. Vlaar, MD, PhD, Tom van der Poll, MD, PhD, W. Joost Wiersinga, MD, PhD, Christopher W. Seymour, MD, MSc, Lonneke A. van Vught, MD, PhD, MARS Consortium

“…Sepsis is an evolving process and proposed subtypes may change over time. …”
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Patient and clinician experiences with the implementation of telemedicine and related adaptations in office-based buprenorphine treatment during the COVID-19 pandemic: a qualitativ... by Melissa Davoust, Angela R. Bazzi, Samantha Blakemore, Juliana Blodgett, Anna Cheng, Sarah Fielman, Kara M. Magane, Jacqueline Theisen, Richard Saitz, Alicia S. Ventura, Zoe M. Weinstein

“…In response to the COVID-19 pandemic, providers of office-based buprenorphine treatment rapidly adapted their care processes, increasingly relying on telemedicine visits. …”
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Loss of OBSCN expression promotes bladder cancer progression but enhances the efficacy of PD-L1 inhibitors by Tao Wang, Tuanjie Guo, Juanjuan Sun, Xinyue Zang, Lei Dong, Jian Zhang, Siteng Chen, Guihua Chen, Sicong Ma, Xinyu Zhai, Chuanmin Chu, Chaofu Wang, Xiang Wang, Dongliang Xu, Mingyue Tan

“…IHC and Western blot assay identified that BLCA samples with low OBSCN expression had more CD8+ T-cell infiltration and higher PD-L1 expression. …”
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Whole-body and site specific [18F]FDG uptake patterns on PET/CT have limited value in differentiating between polymyalgia rheumatica and other inflammatory diseases: two cohorts of... by Andreas Wiggers Nielsen, Gijs D. van Praagh, Kornelis S. M. van der Geest, Ib Tønder Hansen, Berit Dalsgaard Nielsen, Søren Geill Kjær, Jesper Blegvad-Nissen, Kate Rewers, Christian Møller Sørensen, Elisabeth Brouwer, Ellen-Margrethe Hauge, Lars Christian Gormsen, Riemer H. J. A. Slart, Kresten Krarup Keller

“…Results Patients with PMR were more likely than non-PMR patients to have bilateral [18F]FDG-uptake equal to or above liver compared at the ischial tuberosities (91%/41%), shoulder joints (86%/45%), hip joints (83%/52%), and along the lumbar spinal processes (70%/30%). …”
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MiceDEGdb: a knowledge base on differentially expressed mouse genes as a model object in biomedical research by O. A. Podkolodnaya, I. V. Chadaeva, S. V. Filonov, N. L. Podkolodnyy, D. A. Rasskazov, N. N. Tverdokhleb, K. A. Zolotareva, A. G. Bogomolov, E. Yu. Kondratyuk, D. Yu. Oshchepkov, M. P. Ponomarenko

“…The fundamental understanding of many biological processes that unfold in a human body has become possible due to experimental studies on animal models. …”
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Exploration of virulence and immune evasion functions of the candidate vaccine antigen SpyAD in the globally disseminated M1T1 group A Streptococcus strain by Alexandra Stream, Samira Dahesh, Lamar Thomas, Nina J. Gao, Elisabet Bjånes, Kalisa Kang, Truman Koh, Neeraj Kapoor, Victor Nizet

“…To effectively combat these invasive infections, a more thorough understanding of GAS pathogenesis—particularly mechanisms of immune invasion and evasion—is critical. …”
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