Tuberculous meningitis without pleocytosis in an immunocompetent patient: a case report by Dr Hassan Kamena Mwana-yile Mwana-yile, Professor Fatima IHBIBANE, Dr Khadija RIDA, Dr Raissa BONGUNGU, Professor Kamal EL Filali MARHOUM

“…In HIV infection, the level of immunosuppression affects the intracerebral inflammatory process, which explains the lack of pleocytosis in tuberculous meningitis or cryptococcal meningitis.Acellular meningitis is rare in bacterial infections but more common in viral infections in immunocompetent individuals.Tuberculous meningitis cases have been observed with atypical low white blood cell counts in the cerebrospinal fluid, even in individuals with healthy immune systems and in areas where the disease is uncommon. …”
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Effect of dapagliflozin on the structural and functional properties of arterial vessels in patients with type 2 diabetes mellitus in combination with obesity by О. А. Soloviuk, R. L. Kulynych

“…In individuals with increased expression markers of fibrosis TGF-β1, significantly more rigid vessels of the elastic and muscular type are determined, which indicates a possible pathogenetic role of TGF-β1 as one of the potential prognostic biomarkers of arterial stiffness and a negative factor of cardiovascular risk in patients with type 2 DM in combination with EBW.…”
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Unmet needs in the management of hereditary angioedema from the perspective of Brazilian patients by Pedro Giavina-Bianchi, MD, PhD, Mara Giavina-Bianchi, MD, PhD, Raquel de Oliveira Martins, Maria Cristina Fortunato, PharmD, Ana Claudia Guersoni, MD, PhD

“…Diagnosis delays were prevalent, with a significant number reporting 13–50 attacks annually (33%) and 15% experiencing more than 50 attacks per year. Laryngeal involvement was reported by 26% of respondents. …”
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Application of Quality-by-Design Approach to Justify the Composition and Technology of Two-component Suppositories by I. E. Smekhova, L. V. Shigarova, P. I. Andreeva, E. V. Flisyuk, A. S. Dzyuba

“…The difference in the influence of pH and water content on the microbial limits: unlike chlorhexidine bigluconate, which has antiseptic properties, dexpanthenol is more susceptible to microbial contamination. The effect of base CMAs on identification, content uniformity, and assay is not critical. …”
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Pengkontruksian Bidirected Overlap Graph untuk Perakitan Sekuens DNA by Wisnu Ananta Kusuma, Albert Adrianus

“…This method is much more efficient compared to that of using string matching. …”
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Crop classification with deep convolutional neural network based on crop feature by Mohamad Reza Gili, Davoud Ashourloo, Hosein Aghighi, Ali Akbar Matkan, Alireza SHakiba

“…Therefore, methods that are less dependent on ground samples and use phenological features derived from time series of bands and vegetation indices to classify crops will be more appropriate (Ashourloo et al., 2020). The purpose of this study is to use a deep learning method based on convolutional networks to classify the crop types and improve the performance of this network by using feature channels as an input image to the network and increasing the classification accuracy. …”
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Improving AI-Based Clinical Decision Support Systems and Their Integration Into Care From the Perspective of Experts: Interview Study Among Different Stakeholders by Godwin Denk Giebel, Pascal Raszke, Hartmuth Nowak, Lars Palmowski, Michael Adamzik, Philipp Heinz, Marianne Tokic, Nina Timmesfeld, Frank Martin Brunkhorst, Jürgen Wasem, Nikola Blase

“…Suggestions were heterogeneous and concerned improvements: (1) in the systems themselves (eg, implementing comprehensive system training involving [future] users; using a comprehensive and high-quality database; considering usability, transparency, and customizability; preventing automation bias through control mechanisms or intelligent design; conducting studies to demonstrate the benefit of the system), (2) on the user side (eg, training [future] physicians could contribute to a more positive attitude and to greater awareness and questioning decision supports suggested by the system and ensuring that the use of the system does not lead to additional work), and (3) in the environment in which the systems are used (eg, increasing the digitalization of the health care system, especially in hospitals; providing transparent public communication about the benefits and risks of AI; providing research funding; clarifying open legal issues, eg, those related to liability; and standardizing and consolidating various approval processes). …”
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Urban growth simulation using cellular automata model and machine learning algorithms (case study: Tabriz metropolis) by Omid Ashkriz, Babak Mirbagheri, Ali Akbar Matkan, Alireza Shakiba

“…Comparison of the prediction map in the validation period with the current situation of urban areas in 2015 showed that the accuracy of an urban growth simulation model based on random forest with a Figure of Merit index of 0.3569 compared to models based on support vector machine and artificial neural network was more accurate in allocating non-urban to urban lands with 0.3496 and 0.3434, respectively.Conclusion: As machine learning algorithms such as artificial neural networks, support vector machines, and random forest are capable of solving non-linear problems, using them is strongly recommended for urban growth simulation. …”
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Analysis of true triaxial mechanical behavior and energy dissipation of backfill under different unloading rates by Xiaofei LI, Jiajian LI, Yunpeng KOU, Weidong SONG

“…The loading and unloading processes were independently controlled along three principal stress directions (σ1, σ2, and σ3). …”
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Energy utilization potential of Saravan landfill in Rasht with life cycle assessment approach by Ali Ahmadi Orkomi, Maryam Malekpour

“…The leachate treatment process was not investigated because of its negligible effect on the studied indicators. …”
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Serial Estimation of IFN-γ and IP-10 as Biomarkers of Pulmonary Tuberculosis: A Longitudinal Study by Abha Shrivastava, Barnali Kakati, Dipakpak Kumar Dhar, Ashok Kumar Srivastava

“…The reduction was steeper in the first two months and was more marked for IFN-γ, as indicated by their effect size. …”
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Research on Resuspension Mechanism of Aerosols inside Containment during Severe Accidents at Nuclear Power Plant by YANG Yang1, 2, LIU Zhuo3, ZHANG Luteng1, 2, TANG Jiaxuan1, 2, LI Jialong1, 2, PAN Liangming1, 2, GAO Li3, YUAN Yidan3

“…Therefore, aerosol resuspension introduces more uncertainty into the distribution and source term calculations of radioactive substances within the containment during severe accidents. …”
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Research progress on physical and chemical properties of coal gasification slag and its preparation of building materials by Xiaowei GU, Xiaowei GE, Shaoqian LIU, Xuecheng DING, Li WANG, Dongwei HUANG, Dawei WANG, Yile MA

“…The applicability of CGS in different utilization scenarios is further clarified; for instance, CGCS, with its lower carbon content, is more suitable for cementitious or brick materials. …”
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Decreased complement 4 and interleukin-10 as biomarkers in aqueous humour for non-exudative age-related macular degeneration: a case control study by Juliane Schikora, Aaron Dort, Hannah N. Wolf, Mihály Józsi, Richard B. Pouw, Thomas Bertelmann, Dirk Bahlmann, Christian van Oterendorp, Nicolas Feltgen, Hans Hoerauf, Diana Pauly, Jannis Klemming

“…Abstract Background The development of age-related macular degeneration (AMD) is influenced by risk factors that contribute to inflammatory processes, cellular stress responses, and a dysregulation of the complement system. …”
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Exploring the Ethical Challenges of Conversational AI in Mental Health Care: Scoping Review by Mehrdad Rahsepar Meadi, Tomas Sillekens, Suzanne Metselaar, Anton van Balkom, Justin Bernstein, Neeltje Batelaan

“…When a concern occurred in more than 2 articles, we identified it as a distinct theme. …”
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Magnitude of extrapulmonary tuberculosis and its associated factors among TB suspected patients at Wolkite University specialized hospital in central Ethiopia by Asnake Simieneh, Rahel Dereje, Gizachew Ayele Manaye, Admasu Haile Hantalo, Bisrat Fikadu Habtu, Rebie Kedir Negash, Seid Abrar

“…Participants who were HIV positive (AOR = 16.3, 95% CI 8.5–33.0) and those with a prior history of pulmonary TB (AOR = 5.8, 95% CI 2.5–13.2) were more likely to be EPTB positive compared to HIV-negative participants and those without a history of pulmonary TB. …”
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A novel approach for downscaling land surface temperature from 30 m to 10 m using land features multi-interaction by Alfred Homère Ngandam Mfondoum, Sofia Hakdaoui, Ali Mihi, Ibrahima Diba, Mesmin Tchindjang, Luc Beni Moutila, Frederic Chamberlain Lounang Tchatchouang

“…From these results, the downscaling process is efficient in better distinguishing contributions per land feature in diverse urban environments, while more cross-validation based on meteorological stations is still needed.…”
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Comparative Genome Sequencing Analysis of Some Novel Feline Infectious Peritonitis Viruses Isolated from Some Feral Cats in Long Island by Abid Ullah Shah, Blanca Esparza, Oscar Illanes, Maged Gomaa Hemida

“…Diagnostic surveillance with molecular characterization and sequencing analysis of circulating FIPV strains within animal shelters may help early detect unique emerging clinical and pathological manifestations of the disease and develop more targeted prophylactic and therapeutic approaches to control it.…”
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Study of the association of distribution pattern of genotypes of C/A polymorphism of COL1A1_1 collagen gene (RS1107946) with indicators of external breathing in children with bronc... by Т. Ye. Shumna, S. M. Nedelska, O. S. Fedosieieva

“…Homozygous genotype A/A of C/A polymorphism of the COL1A1_1 collagen gene (rs1107946), was associated with more pronounced disorders of ventilatory function of lungs with obstructive breathing type due to impaired collagen formation in the bronchi, which may have prognostic significance both for early diagnosis and prediction of clinical course severity of this disease as well as for prevention and treatment of bronchial obstruction in patients.…”
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Multipurpose prevention technologies for the prevention of unintended pregnancy, HIV, and other sexually transmitted infections: regulatory pathways and challenges by Logan Donaldson, Robin Schaefer, Sarah Alhakimi, Ruth Akulu, Thesla Palanee-Phillips, Thesla Palanee-Phillips, Bethany Young Holt, Veronica Miller

“…MPTs are complex products that typically include multiple active pharmaceutical ingredients (APIs), with two or more indications, and often use a device to deliver these APIs. …”
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