Docking Simulations of G-Protein Coupled Receptors Uncover Crossover Binding Patterns of Diverse Ligands to Angiotensin, Alpha-Adrenergic and Opioid Receptors: Implications for Car... by Harry Ridgway, Graham J. Moore, Laura Kate Gadanec, John M. Matsoukas

“…ARBs block both AngII and alpha receptors, suggesting that they are more potent antihypertensive drugs than ACE inhibitors. …”
Get full text

Effect of Frying Temperature on Lipid Binding, Fatty Acid Composition, and Nutritional Quality of Fish Crackers Prepared from Carp (<i>Ciprinus carpio</i> L.) and Tapioca Starch (<... by Grzegorz Tokarczyk, Grzegorz Bienkiewicz, Patrycja Biernacka, Sylwia Przybylska, Wojciech Sawicki, Małgorzata Tabaszewska

Get full text

FACCE: Framework para Avaliação da Carga Cognitiva na Educação Online / FACCE: Framework for assessing cognitive load in online education by Andressa Falcade, Laís Falcade, Ilse Abegg, Uianes Luiz Rockenbach Biondo

“…. /// Analyzing the cognitive load involved in the online teaching and learning process is an important factor in ensuring more concrete educational results, mainly because it observes the interference that different formats of content presentation can cause in the acquisition of information by human memory. …”
Get full text

Improvement of photocatalytic degradation of organic dyes by vanadium doped titanium oxide nanoparticles using solar simulator by Moustafa. E. Elsisi, A. F. Mansour

“…Solar simulator light was tested for the photodegradation process. Vanadium-doped titanium oxide nanoparticles (V-TiO2 NPs) was successfully synthesized by a sol-gel technique and the solid-state thin films of PVA/dye/V-TiO2 were prepared by a casting method. …”
Get full text

Biomarkers for neurodegenerative diseases in regulatory decision‐making by the European Medicines Agency by Audrey M. M. Hermans, Elisabeth Bakker, Viktoriia Starokozhko, Loes den Otter, André J. A. Elferink, Angela Bradshaw, Lorenzo Guizzaro, Peter G. M. Mol, Anna M. G. Pasmooij

“…DISCUSSION Despite the established role of certain BMs, mainly imaging BMs for MS, there remains a major need for more precise and reliable BMs to improve diagnostic accuracy and treatment monitoring for NDDs. …”
Get full text

Assessing the Impact of Land Use Changes on Ecosystem Service Values in Coal Mining Regions Using Google Earth Engine Classification by Shi Chen, Jiwei Qin, Shuning Dong, Yixi Liu, Pingping Sun, Dongze Yao, Xiaoyan Song, Congcong Li

Get full text

Mechanistic switch in corrosion behavior of magnesium alloy diamond lattice structures induced by argon plasma treatment by Viviana M. Posada, Alexandru Marin, Tonny Naranjo, Juan Ramírez, Patricia Fernández-Morales

“…After 14 days, the DPNS-treated sample exhibited a more positive corrosion potential (-0.69 V versus -1.36 V) and a marginally lower current density (0.73 mA/cm² compared to 0.75 mA/cm²) relative to the control. …”
Get full text

Do European regulatory measures accelerate national market access in Belgium? A retrospective analysis of medicines centrally authorised between 2015 and 2020 by Isabelle Huys, Steffen Fieuws, Zilke Claessens, Joël Daems, Liese Barbier

“…Background At the European level, several regulatory measures (ie, priority medicines (PRIME) scheme, accelerated assessment, conditional marketing authorisation and authorisation under exceptional circumstances) are in place with the aim to expedite the marketing authorisation process for medicines targeting unmet medical needs (UMNs). …”
Get full text

Digital currency: features of regulation in the Russian Federation by T. E. Rozhdestvenskaya, A. G. Guznov

“…Firstly, if the services provided by payment systems are more efficient, reliable, affordable and cheap for the consumer. …”
Get full text

Comparison of the four co-created interventions to improve snacking and physical activity behaviour in European adolescents: the SEEDS project by Judit Queral, Elisabet Llauradó, Annemieke Wargers, Wilma Jansen, Yannis Manios, Amandine Senequier, Craig A. Williams, Dimitris Vlachopoulos, Rosa Solà, Lucia Tarro

“…Conclusions In four co-created interventions by adolescent ambassadors, most of the barriers identified were addressed whereas the facilitators were not enough addressed. Thus, more effort is needed to completely adapt the intervention to the real interest of adolescents. …”
Get full text

Understanding “Alert Fatigue” in Primary Care: Qualitative Systematic Review of General Practitioners Attitudes and Experiences of Clinical Alerts, Prompts, and Reminders by Illin Gani, Ian Litchfield, David Shukla, Gayathri Delanerolle, Neil Cockburn, Anna Pathmanathan

“…Suggestions to improve CR adherence included providing coherent training, enhancing their design, and incorporating more personalized content. Trial RegistrationPROSPERO CRD42016029418; https://www.crd.york.ac.uk/prospero/display_record.php?…”
Get full text

Hasta que los intereses nos separen: conflictos en FIEL y la Fundación Mediterránea by HERNÁN RAMÍREZ

“…These disagreements has shown up the tension generated by the economic restructure that by the time had specially caused impact in some groups of the secondary sector that became more active and joined other groups that represented oth er alternatives to defend better their interests. …”
Get full text

Grazing systems and natural capital: Influence of grazing management on natural capital in extensive livestock production systems by Anthony P. O'Grady, Daniel S. Mendham, Karel Mokany, Greg S. Smith, Stephen B. Stewart, Matthew T. Harrison

“…Increased adoption of processes such as natural capital accounting, although in their infancy, could help to address this challenge and facilitate a more systematic analysis an enterprises natural capital and financial performance.…”
Get full text

Geographical Information System-Based Site Selection in North Kordofan, Sudan, Using In Situ Rainwater Harvesting Techniques by Ibrahim Ahmed, Elena Bresci, Khaled D. Alotaibi, Abdelmalik M. Abdelmalik, Eljaily M. Ahmed, Majed-Burki R. Almutairi

“…However, ground data from field experiments provided more accurate results compared to the FAO suitability map. …”
Get full text

Factors associated with malaria in pregnancy among antenatal care mothers at Gulu Regional Referral Hospital in northern Uganda by Solomon Oguta, Brian Serumaga, Lameck Odongo, Donald Otika, Jackline Ayikoru, Raymond Otim, Jimmyy Opee, Baifa Arwinyo, Francis Pebolo Pebalo, Vincentina Achora, Sande Ojara, Benard Abola, Silvia Awor

“…Results Three hundred fifty (350) pregnant women were recruited; 96% of them slept under mosquito nets daily, while more than half of them (51.7%) had not yet taken SP (IPTp) during their current pregnancy. …”
Get full text

Epidemiological Situation on Tularemia in the far Eastern Federal District (2000-2017) by T. N. Demidova, V. P Popov, T. V. Mikhailova, A. S. Cemichin, Y. S. Podobedova

“…The purpose of this work is to identify the main patterns of functioning and epidemic manifestations of natural foci of tularemia in the far Eastern Federal district (far Eastern Federal district) on the basis of long-term monitoring and using various research methods.Results, The analysis of the epizootic state and epidemic manifestation of natural foci of tularemia in the territory of the far Eastern Federal district for 2000-2017 shows that the main regularities of the epidemic process remain in the natural foci of this infection. …”
Get full text

Early Identification of Cognitive Impairment in Community Environments Through Modeling Subtle Inconsistencies in Questionnaire Responses: Machine Learning Model Development and Va... by Hongxin Gao, Stefan Schneider, Raymond Hernandez, Jenny Harris, Danny Maupin, Doerte U Junghaenel, Arie Kapteyn, Arthur Stone, Elizabeth Zelinski, Erik Meijer, Pey-Jiuan Lee, Bart Orriens, Haomiao Jin

“…This tool simplifies the cognitive impairment assessment process, making it more adaptable and reducing burdens. …”
Get full text

DFT analysis of the [3 + 2] heterocyclization reaction of ((1,2,4-triazole(1,3,4-oxadiazole)-3(2)-yl)methyl)thiopyrimidines by Yu. V. Karpenko

“…The application of solvent models (PCM) allowed for more realistic simulation of reaction conditions. …”
Get full text

Experimental Tailer like Thermal Lag Engine to obtain pressure and volume diagrams//Motor de Lag Térmico experimental tipo Tailer para obtener diagramas de presión y volumen by Carlos Fernández-Aballí-Altamirano, Michaël Calcoen, Edward Vandermeersch, Juan J. González-Bayón

“…Their triangular form shows the effects described by West in the expansion and compression processes caused by the variation of the cold heat transfer area. …”
Get full text

The impact of COVID-19 on young people's mental health, wellbeing and routine from a European perspective: A co-produced qualitative systematic review. by Lindsay H Dewa, Lily Roberts, Elizabeth Choong, Caroline Crandell, Ola Demkowicz, Emma Ashworth, Catia Branquinho, Steph Scott

“…The comparatively little qualitative data found in our review means there is an urgent need for more high-quality qualitative research outside of the UK and/or about the experiences of minoritised groups to ensure all voices are heard and everyone is getting the support they need following the pandemic. …”
Get full text