Evaluating the effects of liraglutide, empagliflozin and linagliptin on mild cognitive impairment remission in patients with type 2 diabetes (LIGHT-MCI): study protocol for a multi... by Jie Liu, Jie Zhang, Wen Zhang, Ying Wang, Lu Zhang, Bing Zhang, Kun Wang, Weili Yan, Yan Bi, Zhou Zhang, Xiang Xu, Wenhui Zhu, Fangyi Li, Xiaoya Zhang, Xiaowei Zhu, Congcong Yu, Huijie Yang, Shihua Chen, Sijue Yang, Beibei Zhai, Tianyu Wu, Shengyi Zhao, Xuewei Tong, Yanjie Duan, Yining Chao, Jindan Wu, Xinhua Ye, Haiyan Cheng

“…Findings from this trial are disseminated through peer-reviewed publications, conference presentations, newsletters and social media.Trial registration number NCT05313529.…”
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PREgnancy Care Integrating translational Science, Everywhere (PRECISE): a prospective cohort study of African pregnant and non-pregnant women to investigate placental disorders – c... by Sanjeev Krishna, Jing Li, Prestige Tatenda Makanga, Helena Boene, Marianne Vidler, Laura A Magee, Esperanca Sevene, Peter von Dadelszen, Anifa Vala, Salésio Macuacua, Sónia Maculuve, Aris Papageorghiou, Veronique Filippi, Lucilla Poston, Aris T Papageorghiou, Melisa Martinez-Alvarez, Geoffrey Omuse, Guy Whitley, Hannah Blencowe, Benjamin Barratt, Rachel Craik, Carla Carrilho, Marleen Temmerman, Kelly Pickerill, Anna Roca, Donna Russell, Rachel M Tribe, Umberto D’Alessandro, Hawanatu Jah, Andrew Prentice, Brahima Diallo, Patricia Okiro, Corssino Tchavana, Lazaro Quimice, Inacio Mandomando, Liberty Makacha, Rachel Tribe, Tatiana Salisbury, Ben Barratt, Alison Noble, Joy Lawn, Matt Silver, Judith Cartwright, Jing (Larry) Li, Domena Tu, Marie-Laure Volvert, Hiten D Mistry, Sophie E Moore, Joseph Akuze, Ursula Gazeley, Onesmus Wanje, Grace Mwashigadi, Abdul Sesay, Sambou Suso, Baboucarr Njie, Fatima Touray, Yahaya Idris, Fatoumata Kongira, Modou F S Ndure, Lawrence Gibba, Abdoulie Bah, Angela Koech, Consolata Juma, Joseph Mutunga, Isaac Mwaniki, Moses Mukhanya, Marvin Ochieng, Emily Mwadime, Thomas Mendy, Jeff Bone, Ash Sandhu, Yorro Bah, Baboucar Bah, Gibril Gabbidon, Reason Mlambo Lucilla Poston, Mai-Lei (Maggie) Woo Kinshella

“…Findings will be disseminated to local stakeholders and communities through meetings and ongoing community engagement and globally by publication and presentations at scientific meetings.…”
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Alteration of m⁶A Methylation in Breast Cancer Cells by <i>Kalanchoe pinnata</i> Aqueous Extract by Carlos Rogelio Alvizo-Rodríguez, Fernando Calzada, Uriel López-Vázquez, Emmanuel Tomay Tiburcio, Juan A. Hernandez-Rivera, Alan Carrasco-Carballo, Marta Elena Hernández-Caballero

“…<i>Kalanchoe pinnata</i> is used in traditional medicine to treat cancer, as it contains flavonoids and phenols known to regulate key cellular processes associated with cancer. Breast cancer, the most common cancer among women globally, presents ongoing challenges in treatment. …”
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LRP6 regulates growth in Litopenaeus vannamei via the Wnt/β-catenin signaling pathway by Sheng Wang, Xiaodi Wang, Hao Yang, Xuanzheng Di, Haoyang Li, Bin Yin, Ziwei Liu, Chaozheng Li, Jianguo He

“…Additionally, LvTcf was found to induce the expression of LvLRP6 and a number of Wnt ligands, thus amplifying Wnt/β-catenin pathway activation and reinforcing the growth-promoting feedback loop. The present investigation demonstrated the importance of LRP6 in shrimp growth, which contributes to our knowledge of the molecular processes that underlie crustacean growth and offers a theoretical basis for breeding and genetic enhancement initiatives aimed at enhancing shrimp aquaculture growth performance.…”
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Treatment of Helicobacter pylori infection: mainstream and innovations (Review of the literature and Russian gastroenterological association Advisory council resolution, May 19, 20... by V. T. Ivashkin, I. V. Mayev, T. L. Lapina, A. A. Sheptulin, A. S. Trukhmanov, R. A. Abdulkhakov, S. A. Alekseyenko, N. N. Dekhnich, R. S. Kozlov, I. L. Klyaritskaya, S. A. Kurilovich, M. F. Osipenko, V. I. Simanenkov, I. B. Khlynov

“…Aim of review. To present data of clinical trials, systematic reviews and metaanalyses which allow to optimize eradication therapy of Helicobacter pylori (H. pylori) infection. …”
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Novel cultivation techniques for water lily (Nymphaea micrantha Guill. & Perr) production based on in vitro technology by Fei Lin, Yong Kang, Arwa Abdulkreem AL-Huqail, Dikhnah Alshehri, Yamei Li, Yuhua Guo, Guangsui Yang, Fenling Tang, Junmei Yin, Zheli Ding, Mamdouh A. Eissa

“…To address the knowledge gap in the use of water lily rhizomes as explants in tissue culture, in this study, the processes of sterilization, induction, proliferation, and rooting in water lily tissue culture are examined. …”
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Long COVID in long-term care: a rapid realist review by Annette Berndt, Valorie A Crooks, Manoj Sivan, Simon Carroll, Maura MacPhee, Shannon Freeman, Karen Davison, Ian Fyffe, Janice Sorensen, Alison Andrews-Paul, Jennifer Walls, Benajir Shams, Akber Mithani

“…Synthesised findings were presented to a reference group and expert panel for confirmatory purposes.Results Fifteen peer-reviewed articles and six grey literature sources were eligible for inclusion. …”
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Metagenomic insights into the microbial communities and functional traits of hot springs in Guizhou Province, China by Feng Chen, Min Cheng, Dongyun Rong, Yanyan Wang, Yanyan Wang, Rubing Liang, Muhammad Irfan, Yingqian Kang, Yu Cao, Yu Cao

“…However, recent studies have determined that hot springs not only have a rich microbiota but are also involved in various biogeochemical processes and possess unique characteristics that can be utilized for several biotechnological applications. …”
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Metal-strong Inflows at the Outer-galactic-scale of a Quasar by Qiguo Tian, Lei Hao, Yipeng Zhou, Xiheng Shi, Tuo Ji, Peng Jiang, Lin Lin, Zhenya Zheng, Hongyan Zhou

“…The metal-strong absorption inflows at the outskirt of the quasar host galaxy most likely originated in situ and were driven by stellar processes, such as stellar winds and/or supernova explosions. …”
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Cohort profile: Understanding the influence of early life environments and health and social service system contacts over time and across generations through the Western Australian... by Alex Brown, Sarah E Johnson, Peter Richmond, Peter Azzopardi, Stephen R Zubrick, Melissa O'Donnell, Juli Coffin, Asha C Bowen, Jenny Downs, Elizabeth A Davis, Hayley M Passmore, Heather A D'Antoine, Helen Milroy, Glenn Pearson, Francis Mitrou, Sharynne L Hamilton, Christopher G Brennan-Jones, Stefanie Schurer, Katherine M Conigrave, Matthew M Cooper, Kathryn A Ramsey, Anna Ferrante, Leah Cave, Philip Vlaskovsky, Katrina D Hopkins, Ted Wilkes

“…All research is guided by Aboriginal governance processes and study outputs will be produced with Aboriginal leadership to guide culturally appropriate policy and practice for improving health, education and social outcomes.…”
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Biochar effects on durum wheat (Triticum durum) under ambient and elevated atmospheric CO2 by Lorenzo Brilli, Franz-Werner Badeck, Lorenzo Genesio, Silvia Baronti, Fulvia Rizza, Clara Fares, Luigi Cattivelli, Franco Miglietta, Anita Maienza, Alessandro Zaldei, Federica Camin, Rosella Motzo, Piero Toscano

“…Accordingly, biochar use could be preferentially adopted for increasing the productivity of high-quality cultivars whose destination and industrial processing would not suffer from a decrease in quality parameters.…”
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‘It’s the perfect storm’: why are people with eating disorders at risk of suicide? A qualitative study by Una Foye, Saakshi Kakar, Niamh McNamara, Agnieszka Musial, Tom Jewell, Jessica R. Griffiths, Carol Kan, Gerome Breen, Rachel Rowan Olive, T. Suratwala, Aman Sidhu, Lizzie Mitchell, George Mycock, Katie Graden, Saskia Evans Perks, Elia Chitwa, Holly Whitehead, Ulrike Schmidt, Rina Dutta, Moritz Herle

“…Participants with lived experience presented with a range of EDs. Clinicians worked across a range of service settings as well as adolescent and adult services. …”
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EURAD state-of-the-art report: thermo-hydro-mechanical behaviour of clay buffers at high temperatures by María Victoria Villar, Katerina Cernochova, Jaime Cuevas, Antonio Gens, Natalia Gimeno, Caroline Graham, Jon Harrington, Vlastislav Kašpar, Stephan Kaufhold, Olivier Leupin, David Mašín, Jan Najser, Markus Olin, Heini Reijonen, Šárka Šachlová, Sergey Sayenko, Daniel Svensson, Jiri Svoboda, Gianni Vettese, Janne Yliharju, Borys Zlobenko

“…A synthesis of the state of knowledge on the thermo-hydro-mechanical and chemical behaviours of different buffer materials at different temperatures is presented, along with the progress made in this area during HITEC. …”
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A semantic strength and neural correlates in developmental dyslexia by Sladjana Lukic, Sladjana Lukic, Sladjana Lukic, Fei Jiang, Maria Luisa Mandelli, Maria Luisa Mandelli, Ting Qi, Sarah M. Inkelis, Sarah M. Inkelis, Emily Rosenthal, Emily Rosenthal, Zachary Miller, Zachary Miller, Emma Wellman, Emma Wellman, Silvia A. Bunge, Silvia A. Bunge, Silvia A. Bunge, Maria Luisa Gorno-Tempini, Maria Luisa Gorno-Tempini, Christa Watson Pereira, Christa Watson Pereira

“…., reading and phonology, among others), but few examine possible strengths. In the present study, we investigated semantic fluency as a cognitive strength in English-speaking children with dyslexia aged 8–13.MethodsNinety-seven children with dyslexia completed tests of letter and semantic verbal fluency, standardized measures of reading and cognitive functions, and task-free resting-state functional magnetic resonance imaging (rs-fMRI). …”
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Deep-ER: Deep Learning ECCENTRIC Reconstruction for fast high-resolution neurometabolic imaging by Paul J. Weiser, Georg Langs, Wolfgang Bogner, Stanislav Motyka, Bernhard Strasser, Polina Golland, Nalini Singh, Jorg Dietrich, Erik Uhlmann, Tracy Batchelor, Daniel Cahill, Malte Hoffmann, Antoine Klauser, Ovidiu C. Andronesi

“…Advanced MRSI using non-cartesian compressed-sense acquisition enables fast high-resolution metabolic imaging but has lengthy reconstruction times that limits throughput and needs expert user interaction. Here, we present a robust and efficient Deep Learning reconstruction embedded in a physical model within an end-to-end automated processing pipeline to obtain high-quality metabolic maps. …”
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Beliefs on the ability to regulate negative emotions mediates the effects of competitive anger on task-focused self-efficacy in taekwondo athletes by Luca Bovolon, Maria Rosaria Nappa, Salvatore Chiodo, Francesca Greco, Katia Folino, Maria Grazia Tarsitano, Maurizio Bertollo, Gian Pietro Emerenziani

“…The focused SE on specific sports tasks has been shown to impact athletic performance by interacting with other self-evaluation processes, like self-efficacy beliefs in emotion-related regulation and effective emotion regulation. …”
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Sexual epigenetics: genome-wide analysis revealed differential DNA methylation in the vector tick Haemaphysalis longicornis by Han Wang, Ziyan Bing, Lu Li, Ziwen Gao, Chuks Fidelis Nwanade, Na Dong, Ke Li, Leyan Du, Zhijun Yu

“…DNA methylation, as a key epigenetic modification, plays a crucial role in biological processes such as the maintenance of normal cellular function, the regulation of gene expression, and embryonic development. …”
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Influence of combined transcranial and peripheral electromagnetic stimulation on the autonomous nerve system on delayed onset muscle soreness in young athletes: a randomized clinic... by Hugo Keriven, Alberto Sánchez Sierra, Ángel González-de-la-Flor, María García Arrabé, Marta de la Plaza San Frutos, Arturo Ladriñán Maestro, Guillermo-Garcia-Perez-de-Sevilla, Jose Francisco Tornero Aguilera, Vicente Javier Clemente Suarez, Diego Domínguez Balmaseda

“…Eccentric exercise, known to induce DOMS, significantly impacts recovery and physiological processes. Electromagnetic stimulation, both transcranial and peripheral, has gained attention in sports medicine due to its demonstrated benefits in various conditions, offering potential as a recovery-enhancing tool for athletes. …”
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Transposon-directed insertion-site sequencing (TraDIS) analysis of Enterococcus faecium using nanopore sequencing and a WebAssembly analysis platform by Alexandra L. Krause, Wytamma Wirth, Adrianna M. Turner, Louise Judd, Lucy Li, Willem van Schaik, Benjamin P. Howden, Glen P. Carter, Torsten Seemann, Ryan Wick, Timothy P. Stinear, Andrew H. Buultjens, Ian R. Monk

“…The application of nanopore sequencing, with a highly accessible sequence data processing and bioinformatic analysis pipeline, streamlines and simplifies the methodology. …”
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Petrogenesis of Middle Silurian Shandan diorites in North Qilian Orogenic Belt, NW China: Insights into post-collisional slab breakoff by Gang Chen, Dechao Li, Dechao Li, Xijun Liu, Xijun Liu, Xijun Liu, Pengde Liu, Zhihan Bai, Xiao Liu, Xiao Liu, Rongguo Hu, Rongguo Hu, Hao Tian, Yande Liu, Wenmin Huang, Yao Xiao

“…Understanding the petrogenesis and tectonic setting of these intrusive rocks is crucial for reconstructing the tectonic evolution and tectonomagmatic processes that occurred along the North Qilian Orogenic Belt between the Alxa and Central Qilian blocks. …”
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