INTERNALIZATION OF ANTIMICROBIAL PEPTIDE ACIPENSIN 1 INTO HUMAN TUMOR CELLS by E. S. Umnyakova, I. V. Kudryavtsev, N. A. Grudinina, S. V. Balandin, I. A. Bolosov, P. V. Panteleev, T. A. Filatenkova, D. S. Orlov, E. V. Tsvetkova, T. V. Ovchinnikova, V. N. Kokryakov, O. V. Shamova

“…These data support the concept, that the antimicrobial peptides of innate immunity system possess the features of cell-penetrating peptides, and allow us to consider the studied sturgeon peptide a promising template for development of new drugs with increased ability to enter the cells implicated into pathological processes, and, therefore, higher therapeutic efficiency.…”
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Montrends: A Google Earth engine application for analysing species' habitat suitability over time by João Alírio, Nuno Garcia, João C. Campos, Salvador Arenas-Castro, Isabel Pôças, Lia B. Duarte, Ana Cláudia Teodoro, Neftalí Sillero

“…Remote sensing has played a crucial role in supporting biodiversity monitoring, but more intuitive and fast-processing tools are still required to improve biodiversity conservation. …”
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Identifying PM2.5-bound metal pollution sources in Southern Thailand using positive matrix factorization and principal component analysis by Siwatt Pongpiachan, Sarunpron Khruengsai, Teerapong Sripahco, Radshadaporn Janta, Rungruang Janta, Jompob Waewsak, Danai Tipmanee, Saran Poshyachinda, Patcharee Pripdeevech

“…This study presents the first integrated source apportionment and health risk assessment of PM2.5-bound metals in Southern Thailand using Positive Matrix Factorization (PMF) and Principal Component Analysis (PCA). …”
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Overview of physics results from MAST upgrade towards core-pedestal-exhaust integration by J.R. Harrison, A. Aboutaleb, S. Ahmed, M. Aljunid, S.Y. Allan, H. Anand, Y. Andrew, L.C. Appel, A. Ash, J. Ashton, O. Bachmann, M. Barnes, B. Barrett, D. Baver, D. Beckett, J. Bennett, J. Berkery, M. Bernert, W. Boeglin, C. Bowman, J. Bradley, D. Brida, P.K. Browning, D. Brunetti, P. Bryant, J. Bryant, J. Buchanan, N. Bulmer, A. Carruthers, L. Casali, M. Cecconello, Z.P. Chen, J. Clark, C. Cowley, M. Coy, N. Crocker, G. Cunningham, I. Cziegler, T. Da Assuncao, Y. Damizia, P. Davies, I.E. Day, G.L. Derks, S. Dixon, R. Doyle, M. Dreval, M. Dunne, B.P. Duval, T. Eagles, J. Edmond, H. El-Haroun, S.D. Elmore, Y. Enters, M. Faitsch, F. Federici, N. Fedorczak, F. Felici, A.R. Field, M. Fitzgerald, I. Fitzgerald, R. Fitzpatrick, L. Frassinetti, W. Fuller, D. Gahle, J. Galdon-Quiroga, L. Garzotti, S. Gee, T. Gheorghiu, S. Gibson, K.J. Gibson, C. Giroud, D. Greenhouse, V.H. Hall-Chen, C.J. Ham, R. Harrison, S.S. Henderson, C. Hickling, B. Hnat, L. Howlett, J. Hughes, R. Hussain, K. Imada, P. Jacquet, P. Jepson, B. Kandan, I. Katramados, Y.O. Kazakov, D. King, R. King, A. Kirk, M. Knolker, M. Kochan, L. Kogan, B. Kool, M. Kotschenreuther, K. -W. Lee, M. Lees, A.W. Leonard, G. Liddiard, B. Lipschultz, Y.Q. Liu, B.A. Lomanowski, N. Lonigro, J. Lore, J. Lovell, S. Mahajan, F. Maiden, C. Man-Friel, F. Mansfield, S. Marsden, R. Martin, S. Mazzi, R. McAdams, G. McArdle, K.G. McClements, J. McClenaghan, D. McConville, K. McKay, C. McKnight, P. McKnight, A. McLean, B.F. McMillan, A. McShee, J. Measures, N. Mehay, C.A. Michael, F. Militello, D. Morbey, S. Mordijck, D. Moulton, O. Myatra, A.O. Nelson, M. Nicassio, M.G. O’Mullane, H.J.C. Oliver, P. Ollus, T. Osborne, N. Osborne, E. Parr, B. Parry, B.S. Patel, D. Payne, C. Paz-Soldan, A. Phelps, L. Piron, C. Piron, G. Prechel, M. Price, B. Pritchard, R. Proudfoot, H. Reimerdes, T. Rhodes, P. Richardson, J. Riquezes, J.F. Rivero-Rodriguez, C.M. Roach, M. Robson, K. Ronald, E. Rose, P. Ryan, D. Ryan, S. Saarelma, S. Sabbagh, R. Sarwar, P. Saunders, O. Sauter, R. Scannell, T. Schuett, R. Seath, R. Sharma, P. Shi, B. Sieglin, M. Simmonds, J. Smith, A. Smith, V. A. Soukhanovskii, D. Speirs, G. Staebler, R. Stephen, P. Stevenson, J. Stobbs, M. Stott, C. Stroud, C. Tame, C. Theiler, N. Thomas-Davies, A.J. Thornton, M. Tobin, M. Vallar, R.G.L. Vann, L. Velarde, K. Verhaegh, E. Viezzer, C. Vincent, G. Voss, M. Warr, W. Wehner, S. Wiesen, T.A. Wijkamp, D. Wilkins, T. Williams, T. Wilson, H.R. Wilson, H. Wong, M. Wood, V. Zamkovska

“…Recent results from MAST Upgrade are presented, emphasising understanding the capabilities of this new device and deepening understanding of key physics issues for the operation of ITER and the design of future fusion power plants. …”
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Preliminary results of the EPIDIA4Kids study on brain function in children: multidimensional ADHD-related symptomatology screening using multimodality biometry by Yanice Guigou, Alexandre Hennequin, Théo Marchand, Théo Marchand, Mouna Chebli, Lucie Isoline Pisella, Pascal Staccini, Pascal Staccini, Vanessa Douet Vannucci, Vanessa Douet Vannucci

“…Biometric constructs were predictors of working memory (p < 0.0001) and processing speed (p < 0.0001) and, to a lower extent, visuo-spatial skills (p = 0.003), inattention (p = 0.04), or achievement (p = 0.04), where multimodalities are crucial to capture several symptomatology dimensions. …”
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Effects of a Complex Feed Additive on Productivity and Blood Parameters of Laying Hens Using Stochastic Fractal-based Neural Network Model by Larisa Karpenko, Alesya Bakhta, Olga Babich, Stanislav Sukhikh, Nikolay Vorobyov, Ilya Nikonov, Solomonida Borisova, Darren Griffin, Michael Romanov

“…Further, EuclidNN computed the respective bioconsolidation indices of hens and, simultaneously, processed several profiles of OTUs for all experimental variants. …”
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Identify the potential target of efferocytosis in knee osteoarthritis synovial tissue: a bioinformatics and machine learning-based study by Shangbo Niu, Shangbo Niu, Shangbo Niu, Mengmeng Li, Mengmeng Li, Mengmeng Li, Jinling Wang, Jinling Wang, Jinling Wang, Peirui Zhong, Peirui Zhong, Peirui Zhong, Xing Wen, Xing Wen, Xing Wen, Fujin Huang, Fujin Huang, Fujin Huang, Linwei Yin, Linwei Yin, Linwei Yin, Yang Liao, Yang Liao, Yang Liao, Jun Zhou, Jun Zhou, Jun Zhou

“…These targets may modulate synovial efferocytosis-related immune processes, offering novel therapeutic avenues for KOA intervention.…”
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Citral protects against metabolic endotoxemia, and systemic disorders caused by high-fat diet-induced obesity via intestinal modulation by Maycon Tavares Emílio-Silva, Vinicius Peixoto Rodrigues, Mariana Moraes Fioravanti, Antonio Jesús Ruiz-Malagon, Matheus Naia Fioretto, Priscila Romano Raimundo, Rie Ohara, Renata Assunção, Gabriela Bueno, Felipe Lima Dario, Luis Antonio Justulin, Alba Rodríguez-Nogales, Lucia Regina Machado da Rocha, Júlio Gálvez, Júlio Gálvez, Clélia Akiko Hiruma-Lima

“…BackgroundObesity is a growing global epidemic associated with changes in the gut microenvironment and metabolic endotoxemia, which can exacerbate metabolic and inflammatory processes. Citral (CT), a monoterpene present in essential oils, has been investigated for its anti-inflammatory, antioxidant, and immunomodulatory properties. …”
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The ALMA Survey of Gas Evolution of PROtoplanetary Disks (AGE-PRO). I. Program Overview and Summary of First Results by Ke Zhang, Laura M. Pérez, Ilaria Pascucci, Paola Pinilla, Lucas A. Cieza, John Carpenter, Leon Trapman, Dingshan Deng, Carolina Agurto-Gangas, Anibal Sierra, Nicolás T. Kurtovic, Dary A. Ruiz-Rodriguez, Miguel Vioque, James Miley, Benoît Tabone, Camilo González-Ruilova, Rossella Anania, Giovanni P. Rosotti, Estephani TorresVillanueva, Michiel R. Hogerheijde, Kamber Schwarz, Aleksandra Kuznetsova

“…We present the Atacama Large Millimeter/submillimeter Array Survey of Gas Evolution of PROtoplanetary Disks (AGE-PRO), a large program of the ALMA. …”
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Potential of C-band Sentinel-1 InSAR for ground surface deformation monitoring in the southern boreal forest: An investigation in the Genhe River basin by Chenqi Huang, Lingxiao Wang, Lin Zhao, Shibo Liu, Defu Zou, Guangyue Liu, Guojie Hu, Erji Du, Yao Xiao, Chong Wang, Yuxin Zhang, Yuanwei Wang, Yu Zhang, Zhibin Li

“…The retrieved seasonal deformation and deformation processes have a high potential for identifying wetlands, differentiating between forest types, and providing valuable insights into the hydrothermal conditions and dynamics of the boreal ecosystem.…”
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Non-coding RNAs: emerging biomarkers and therapeutic targets in cancer and inflammatory diseases by Basma Hossam Abdelmonem, Basma Hossam Abdelmonem, Lereen T. Kamal, Lilian Waheed Wardy, Lilian Waheed Wardy, Manon Ragheb, Manon Ragheb, Mireille M. Hanna, Mohamed Elsharkawy, Anwar Abdelnaser

“…This approach ensures that the findings presented are based on high-quality and relevant sources.…”
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The association of single nucleotide polymorphisms in tumor necrosis factor 3 with susceptibility/resistance of Magallana gigas to Halomonas sp. 7T by Hongmei Fan, Qingyu Peng, Tianbao Liu, Lei Fang, Chuanyan Yang, Ning Kong, Lingling Wang, Linsheng Song

“…Tumor necrosis factors (TNFs) are a group of multifunctional inflammatory cytokines involved in various pathological and immune processes. In the present study, a TNF-3 was characterized in Pacific oyster Magallana gigas (MgTNF-3), and its association of single nucleotide polymorphisms with susceptibility/resistance of oyster to Halomonas sp. 7T were investigated. …”
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Cellular and physiological functions of SGR family in gravitropic response in higher plants by Yuhan Cho, Yujeong Kim, Hyebi Lee, Sundong Kim, Jaehee Kang, Ulhas S. Kadam, Soon Ju Park, Woo Sik Chung, Jong Chan Hong

“…Eventually, we focus on the role of multiple SGR genes in shoot and present a complete update on the participation of SGR family members in gravity.…”
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Metabolome-wide associations with short-term exposure to PM2.5-bound polycyclic aromatic hydrocarbons: a study in older adults by Haoneng Hu, Quan Zhou, Kang Cao, Yu Jiang, Jianjun Xiang, Jing Wu, Jin Li, Zhiwei Chen, Shuling Kang, Dandan Zhu, Huaying Lin, Chuancheng Wu

“…Our findings suggest that the cholesterol and citric acid metabolites, as well as the cholesterol biosynthesis and citric acid cycle pathways they affect, may play important roles in the health damage caused by PAHs, providing potential insights into the pathogenic processes underlying the impact of PM2.5-bound PAHs.…”
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Deterministic Light Detection and Ranging (LiDAR)-Based Obstacle Detection in Railways Using Data Fusion by Susana Dias, Pedro J. S. C. P. Sousa, João Nunes, Francisco Afonso, Nuno Viriato, Paulo J. Tavares, Pedro M. G. P. Moreira

“…Using a data fusion approach, pre-existing knowledge about the track topography is incorporated into the LiDAR data processing pipeline in conjunction with the DBSCAN clustering algorithm to identify and classify potential obstacles based on point cloud density patterns. …”
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Barriers to the implementation of psychosocial interventions on acute mental health wards: an ethnographic observational study by Katherine Berry, Katherine Berry, Isobel Johnston, Isobel Johnston, Paul Wilson, Gillian Haddock, Gillian Haddock, Sandra Bucci, Sandra Bucci, Karina Lovell, Owen Price, Adele Beinaraviciute, Adele Beinaraviciute, Gill Gilworth, Sonalia Kaur, Helen Morley, Helen Morley, Georgia Penn, Georgia Penn, Jessica Raphael, Jessica Raphael, Mica Samji, Richard J. Drake, Richard J. Drake, Dawn Edge, Dawn Edge

“…BackgroundIt is notoriously challenging to deliver psychosocial interventions on acute mental health wards. This paper presents an ethnographic observational study which captured how ward and staff processes impacted on the delivery of a psychosocial intervention called TULIPS (Talk, Understand and Listen for Inpatient Settings). …”
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Resilience investments under climate change: a regional case study in Southeast Australia by Paul J. Box, Stefanos Xenarios, Stefanos Xenarios, Russell M. Wise, Russell M. Wise, Peter Heinmiller, Chandrama Sarker, Petina L. Pert, Seona Meharg, Gemma Edwards, Russell Gorddard, Sofia Azevedo, Dianne Flett, Nic Mesic, Maryam Ahmad, John Marinopoulos, Greg Parish, Jacqui Montgomery

“…This study proposes a discursive, place-based, and cross-scale approach to overcoming these challenges and enabling councils to develop resilient investment cases (RICs) as part of regional planning processes involving local governments, research institutions, and private sector stakeholders. …”
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Combined Effect of HF‐rTMS and Whole‐Body Vibration Exercise on Cognitive Efficiency in Esports Players With or Without Sedentary Behaviors: A Randomized Controlled Trial by Shan He, Lu Leng, Dongdong Gao, Yu Chen, Weiji Deng, Jiarui Wu, Peilun Li, Yilin Chen, Jinglin Huang, Guoqing Liu, Jiarui Su, Jianwei Peng, Wenhuang Guo, Junfeng Zhang, Junhao Huang

“…The interventions, both HF‐rTMS and WBVT, significantly enhanced cognitive processing speed and accuracy, with these improvements being more pronounced in sedentary esports players compared to non‐sedentary esports players. …”
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Urinary elementomic analysis indicates aluminum as a potential urinary biomarker of sarcopenia in the older adults by Mei-Lin Li, Yi-Min Li, Jing-Jing Huang, Zhi-Yue Wang, Quan Wang, Can Zhao, Xiang Lu, Jin-Shui Xu, Zheng-Kai Shen, Wei Gao

“…Biometals and trace elements provide a potential connection linking the environment and lifestyle to pathological processes of sarcopenia. The aim of the present study was to investigate the relationship between urinary trace elements levels and the presence of sarcopenia. …”
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Development and application of solid phase microextraction tips (SPME LC tips) method for therapeutic drug monitoring of gefitinib by LC-MS/MS by Leonardo Costalonga Rodrigues, Lílian de Araújo Lima, Débora Zorrón Berlinck, Mariana Vieira Morau, Mauricio Wesley Perroud Junior, Patrícia Moriel, Jose Luiz Costa

“…No carryover was observed and stability study was successfully applied for processed samples maintained in the autosampler at 10 °C for 24 h The method was applied for four authentic samples from individuals under gefitinib treatment, detecting gefitinib from 104.6 ng/mL to 777.1 ng/mL and O-desmethyl-gefitinib from 85.2 ng/mL to 499.2 ng/mL. …”
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