Fermi-LAT Detection of the Low-luminosity Radio Galaxy NGC 4278 during the LHAASO Campaign by Ettore Bronzini, Paola Grandi, Eleonora Torresi, Sara Buson

“…We present a study of the high-energy properties of the compact symmetric object NGC 4278, recently associated with a TeV source by the Large High Altitude Air Shower Observatory (LHAASO) collaboration. …”
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Impact of social determinants of health on rehabilitation service use and outcomes in adults in the USA: a scoping review protocol by Alicia A Livinski, Jordan Wickstrom, Emma J Leone, Noa Sasson, Hailey C Morris, Nathan D Camarillo, Justine Lely, Rajpriya Venkatarajan, Julie Goldberg, Afua Asante-Otoo, Elizabeth K Rasch

“…Screening and data extraction processes will be piloted. The results will be presented in tables, graphs and narrative summaries.Ethics and dissemination Findings will be disseminated through scientific conferences, professional networks, stakeholder meetings, invited workshops and webinars, email listservs of professional associations, academic social media and in a peer-reviewed journal. …”
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Secreted retropepsin-like enzymes are essential for stress tolerance and biofilm formation in Pseudomonas aeruginosa by Justin D. Lormand, Charles H. Savelle, Jennifer K. Teschler, Eva López, Richard H. Little, Jacob G. Malone, Fitnat H. Yildiz, María J. García-García, Holger Sondermann

“…ABSTRACT Proteases regulate important biological functions. Here, we present the structural and functional characterization of three previously uncharacterized aspartic proteases in Pseudomonas aeruginosa. …”
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Improving Satellite Imagery Masking Using Multitask and Transfer Learning by Rangel Daroya, Luisa Vieira Lucchese, Travis Simmons, Punwath Prum, Tamlin Pavelsky, John Gardner, Colin J. Gleason, Subhransu Maji

“…., satellite imagery and elevation maps) and lack of precision in individual processing steps, which degrade estimation accuracy. …”
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Mechanical stress facilitates calcium influx and growth of alveolar epithelial cells via activation of the BDKRB1/Ca2+/CaMKII/MEK1/ERK axis by Ying Zhang, Qing-dong Zhang, Quan Li, Zhi-yue Shi, Cheng Pan, Rong-shuang Yan, De-rui Fei, Shi-xin Xu, Yang Luo

“…Our previous research demonstrated that BDKRB1/Ca2+ signal transduction may be involved in lung dysplasia resulting from scoliosis and thoracic insufficiency. Therefore, the present study aims to investigate the effects of mechanical stress on the growth and calcium influx in alveolar epithelial cells, as well as the role of BDKRB1/Ca2+ signaling in these processes. …”
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Snapshot of Obstetric National Audit and Research Project (SONAR1): aprotocol for an international observational cohort study by S Ramani Moonesinghe, Bo Hou, Brendan Carvalho, Samantha Hill, Pervez Sultan, Susanna Stanford, Nuala Lucas, James O’Carroll, Reshma Patel, Justin Kua, Nadir El Sharawi, Victoria Eley, Pat O’Brien, Robert Craig

“…The results will be disseminated via conference presentations, peer-reviewed academic journals and reports prepared for patients, the public and policy makers.Trial registration number ISRCTN15269213.…”
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Development of a fully integrated hydrological fate and transport model for plant protection products: incorporating groundwater, tile drainage, and runoff by Michael V. Callaghan, Steven K. Frey, Steven K. Frey, Killian Miller, Hyoun-Tae Hwang, Hyoun-Tae Hwang, Reza Zolfaghari, Klaus Hammel, Steven J. Berg, Steven J. Berg, Edward A. Sudicky, Edward A. Sudicky

“…In the context of PPP authorization and registration, water exposure assessments (drinking water and aquatic exposure) use numerical modeling to simulate relevant hydrological processes and exposure pathways. A common practice for estimating PPP leaching to groundwater, PPP loading onto surface water via tile drainage, or PPP transport via runoff utilizes multiple one-dimensional models, each representing a separate exposure pathway. …”
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GERD-associated laryngeal granuloma: a series of clinical observations. Case report by Svetlana V. Starostina, Olga V. Tashchyan, Marina G. Mnatsakanyan, Konstantin A. Nazarov, Liana S. Karapetyan, Polina A. Loskutova, Irina V. Kuprina

“…Laryngeal granuloma is a benign neoplasm located on the vocal processes of the arytenoid cartilage. The causes of development may be prolonged or traumatic intubation (23%), gastroesophageal reflux disease leading to chronic cough (30%), excessive vocal load (33%); respectively, post-intubation, contact and idiopathic granulomas are distinguished. …”
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Efficient and accurate tobacco leaf maturity detection: an improved YOLOv10 model with DCNv3 and efficient local attention integration by Yi Shi, Hong Wang, Fei Wang, Yingkuan Wang, Jianjun Liu, Long Zhao, Hui Wang, Feng Zhang, Qiongmin Cheng, Shunhao Qing

“…Future research endeavors will be directed towards further optimization of the model’s architecture to bolster its generalizability and to explore its implementation within the realm of actual tobacco cultivation and processing.…”
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Attapulgite/oyster shell composite reduces cadmium and lead bioavailability in acidic agricultural soils through synergistic adsorption and pH regulation by Hongyan Zhu, Yangping Wen, Qingyin Shang, Xinyu Chen, Yuzhen Huang, Peiyue Liu, Chengcheng Wang, Xiuxia Yang

“…Kinetic studies indicated that Pb(II) adsorption occurred at a significantly faster rate than Cd(II), with the adsorption processes aligning well with the pseudo-second-order model, suggesting chemisorption as the primary mechanism. …”
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AgriLink: an innovative real-time data monitoring and connectivity platform for an orange orchard in Morocco by Kamal Baraka, Jamal Ezzahar, Jamal Ezzahar, Mohammed Madiafi, Hassan Erraji, Hassan Erraji, Gaetano Alessandro Vivaldi, Anas Tallou

“…Ensuring global food security, particularly for small-scale farms, presents a major challenge for the scientific community in the coming decades. …”
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Taxane-Producing Fungi Isolated from <i>Taxus globosa</i> Tree Bark by Jocelyn Guadalupe Guevara-Sánchez, María Guadalupe Aguilar-Uscanga, Carlos Augusto Ledesma-Escobar, Claudia Castro-Martínez, Renaud Condé, Bernardo Sachman-Ruíz, Sandra del Moral

“…Even though a great deal of research has been carried out to produce them synthetically, this manufacturing is still dependent on <i>Taxus</i> cell culture. Furthermore, these processes are not suitable for steady taxane production. …”
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Comparative analysis of 3D-culture techniques for multicellular colorectal tumour spheroids and development of a novel SW48 3D-model by Carlos Mateos-Sánchez, Beatriz González, Gisela de Miguel-García, Aida Font-Cugat, Iris Marcote-Corral, Sergio Alonso

“…However, generating consistent spheroids across different CRC cell lines presents technical challenges, and protocols remain inconsistent. …”
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Stage-Dependent Regulation of Dental Pulp Stem Cell Odontogenic Differentiation by Transforming Growth Factor-β1 by Yu Bai, Xin Liu, Junqing Li, Zhihua Wang, Qian Guo, Min Xiao, Paul R. Cooper, Qing Yu, Wenxi He

“…Overall, these findings indicate that TGF-β1 promotes odontogenic differentiation of DPSCs at early-stage while inhibiting later-stage mineralization processes.…”
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Competency self-assessment for a learning-based autonomous aircraft system by Nicholas Conlon, Aastha Acharya, Jamison McGinley, Trevor Slack, Camron A. Hirst, Marissa D’Alonzo, Mitchell R. Hebert, Christopher Reale, Eric W. Frew, Rebecca Russell, Nisar R. Ahmed

“…A central challenge to this new paradigm of non-co-located mission supervision is developing systems which have explainable and trustworthy autonomy and internal decision-making processes.MethodsCompetency self-assessments are methods that use introspection to quantify and communicate important information pertaining to autonomous system capabilities and limitations to human supervisors. …”
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A progressive knowledge strategy for monitoring soil microbiological activity by microscale spectroscopic detection by Heidy Soledad Rodríguez-Albarracín, José A.M. Demattê, Nícolas Augusto Rosin, Jorge Tadeu Fim Rosas, Aquiles Enrique Darghan, Hudson Wallace Pereira de Carvalho

“…Microbial activity plays a critical role in the degradation of soil organic matter (SOM) through intra- and extracellular enzymatic processes. Within SOM, mineral-associated organic matter (MAOM) represents the most transformed microbial material, whereas particulate organic matter (POM) serves as its primary substrate. …”
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Prediction of sugar beet yield and quality parameters using Stacked-LSTM model with pre-harvest UAV time series data and meteorological factors by Qing Wang, Ke Shao, Zhibo Cai, Yingpu Che, Haochong Chen, Shunfu Xiao, Ruili Wang, Yaling Liu, Baoguo Li, Yuntao Ma

“…However, traditional methods are constrained by reliance on empirical knowledge, time-consuming processes, resource intensiveness, and spatial-temporal variability in prediction accuracy. …”
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Seed Protein Content Estimation with Bench-Top Hyperspectral Imaging and Attentive Convolutional Neural Network Models by Imran Said, Vasit Sagan, Kyle T. Peterson, Haireti Alifu, Abuduwanli Maiwulanjiang, Abby Stylianou, Omar Al Akkad, Supria Sarkar, Noor Al Shakarji

“…This study’s findings highlight the significant potential of hyperspectral imaging and machine learning techniques for advancing precision breeding practices, optimizing seed sorting processes, and enabling targeted agricultural input applications.…”
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Evaluation of clinical impact of Interleukin 8 gene expression in patients with fibromyalgia by Carolina Dias da Silva Amorim, Marco Felipe Macêdo Alves, Marcella Dias Teixeira, Larissa Vasconcelos Queiroz, Thaysa Walleria de Aragão Santos, Aline Ranzolin, Danyelly Bruneska Gondin Martins, Claudia Diniz Lopes Marques

“…Abstract Background Fibromyalgia (FM) is a musculoskeletal syndrome characterized by diffuse and chronic pain associated with other symptoms such as fatigue, sleep/cognition disorders, headache, depression and anxiety, resulting from a change in pain processing. Previous research has shown an increase in some interleukins (IL) in patients with FM when compared to controls, however, there is still no uniformity and consensus in the results. …”
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Cyclooxygenase-1 deletion in 5 × FAD mice protects against microglia-induced neuroinflammation and mitigates cognitive impairment by Jie Wang, Hong Ni, Yu Wang, Luyao Wei, Hanqing Ding, Zhongzhao Guo, Hao Pan, Ying Yu, Jia Luo, Weidong Pan, Deheng Wang, Zun-Ji Ke

“…Here, we aimed to elucidate the specific mechanisms of COX1 in AD pathogenesis and its interactions with neuroinflammatory processes. Methods We conducted backcrossing between COX-1 knockout (KO) and 5 × FAD mice to evaluate the effect of COX-1 deficiency on neuroinflammation. …”
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