Zeolitic Imidazolate Framework-90 Treats Fungal Keratitis by Promoting Macrophage Apoptosis and Targeting Increased Mitochondrial Reactive Oxygen Species in Aspergillus Fumigatus by Fu X, Zhang L, Lin J, Wang Q, Wang Z, Chi M, Li D, Zhao G, Li C

“…Xueyun Fu,1 Lina Zhang,1 Jing Lin,1 Qian Wang,1 Ziyi Wang,1 Menghui Chi,1 Daohao Li,2 Guiqiu Zhao,1 Cui Li1 1Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China; 2State Key Laboratory of Bio-fibers and Eco-Textiles, Institute of Marine Biobased Materials, College of Materials Science and Engineering, Qingdao University, Qingdao, People’s Republic of ChinaCorrespondence: Guiqiu Zhao, Department of Ophthalmology, Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong, 266003, People’s Republic of China, Email zhaoguiqiu_good@126.com Cui Li, Department of Ophthalmology, Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, Shandong, 266003, People’s Republic of China, Email yankelicui@126.comBackground: Fungal keratitis is a severe vision-threatening corneal infection with a prognosis influenced by fungal virulence and the host’s immune defense mechanisms. However, there is still a lack of effective drugs that attenuate fungal virulence while relieving the inflammatory response caused by fungal keratitis.Purpose: Finding an effective treatment to solve these problems is particularly important.Methods: We synthesized Zeolitic imidazolate framework-90 (ZIF-90) by water-based synthesis method and characterized it. …”
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Bronchial Lavage in the Treatment of Severe Bronchopulmonary Pathology in Adults. Approaches to Classification by E. U. Bonitenko, A. V. Shchegolev, S. A. Vasilev, N. A. Belyakova, A. I. Kuzmin, E. D. Sokolova

“…It should also be noted that bronchial lavage for therapeutic purposes is justified from a pathoanatomical and pathophysiological point of view, but is accompanied by serious, albeit temporary, changes in the lungs, which can be partially avoided by improving the lavage technique.Conclusion All of the above indicates that in order to solve existing problems, it is necessary to conduct systematic research in this direction with the involvement of all interested specialists.…”
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Sistem Pakar untuk Diagnosis Penyakit Tiroid dengan Gejala Psikologis Beserta Pengobatan Etnobotaninya by Rosyid Ridlo Al-Hakim, Yanuar Zulardiansyah Arief, Muhammad Haikal Satria, Agung Pangestu, Hexa Apriliana Hidayah, Glagah E. Setyowisnu, Prihantini Prihantini, Antonius Darma Setiawan, Esa Rinjani Cantika Putri

“…Abstract The role of an expert system can help an expert solve problems in a particular field. One of the benefits of the expert system is that it is used to diagnose a specific disease or symptom of a disease. …”
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THE ROLE OF THE HUMANITIES AND SOCIAL SCIENCES IN HIGHER EDUCATION: INTERNATIONAL EXPERIENCE by N. Kliuchkovska

“…In particular, it is beyond our competence to solve the essential problems of stability, welfare and peace. …”
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The intersection of Interprofessional Education and One Health: A qualitative study in human and veterinary medical institutions by Claire Tucker, Jake Keyel, Amy Blue, Ruthanne Chun, Amara Estrada, Hossein Khalili, Anuja Riles, Rohini Roopnarine, Brian Sick, Sue VandeWoude, Brittany Watson, Lauren Wisnieski, Tracy Webb

“…The ultimate goal of this work is to help cultivate transdisciplinary leaders in the human and animal medicine who will have the skills to solve systemic problems.…”
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PTEN/PI3K/AKT pathway activation with hypoxia-induced human umbilical vein endothelial cell exosome for angiogenesis-based diabetic skin reconstruction by Zhenming Li, Yuhao Bai, Hao Wu, Yisheng Feng, Xinxi Wang, Cancan Zhao, Xudong Wang

“…Exosomes have been proven to have excellent biological activities and applied to solve many bioengineering problems. However, the wide application of exosomes is still limited by their short in vitro lifetime and low yield. …”
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Enlargement of the European Union and security of the Baltic states by Algirdas Gricius

“…In the article, the author notes that issues of security and stability seem to be the most difficult to solve throughout the history of international relations. …”
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“Agent – Environment” Evolution Mechanism of Greenbelt from the Perspective of Complex Adaptive System: A Case Study of Beijing’s Greenbelts by Song LIU, Peiyu SHEN, Dizi LIU, Zhaocheng BAI

“…ObjectiveSince the first successful practice in London in the 1930s, greenbelt has become an important land control and land use planning idea. Greenbelts help solve problems related to urban sprawl and provide multiple ecological, social and economic functions that have profound impact on sustainable regional development. …”
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The Bioethics-CSR Divide by Caio Caesar Dib

“…Both bioethics and CSR should acknowledge that they hold two different pieces of a cognitive competence necessary for that task: CSR offers experience on how to turn corporate ethical obligations operational, while bioethics provides access to the prevailing practical and philosophical problem-solving tools in healthcare that were born out of social movements. …”
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Dual-channel Potential Energy Recovery and Load Balancing Methods for Large Hydraulic Excavators by Weiping WANG, Shun LU

“…To solve these problems, the research object here is a large hydraulic excavator, for which is proposed a direct/indirect dual-channel boom potential energy recovery system comprising a three-chamber balance cylinder, two accumulators, and a fan motor.Methods In this study, the traditional single accumulator recovery channel (single-channel system) is changed to a dual accumulator recovery channel (dual-channel system), where the three-chamber balance cylinder and accumulator 1 form a direct recovery channel, while the fan motor and accumulator 2 form an indirect recovery channel. …”
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Investigating and Determining the Priorities for Capital Organizing in Iran by Mohammad Mirehei, Amir Fathi, Sohrab Amirian, Hatem Parnian

“…The subject of organizing the capital affects not only this city and its surrounding regions but also whole the country directly or indirectly. So to solve Tehran’s problems we should consider the different aspects of spatial planning in Tehran and whole country. …”
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Project quality, regulation quality by Elena Mussinelli

“…They are either incapable of producing the desired results, or are not the cause of effects even diametrically opposed to those expected. The attempt to solve every problem through a special regulation results in limiting the free and responsible action of citizens (and planners). …”
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COOLFACADE by Alejandro Prieto Hoces

“…The exploration of design and construction requirements is conducted through the identification of the main perceived problems for the façade integration of building services and solar technologies, by means of a survey addressed to façade professionals. …”
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Navigating Ethical Dilemmas Of Generative AI In Medical Writing by Qurrat Ulain Hamdan, Waleed Umar, Mahnoor Hasan

“…The speed with which generative AI chatbots solve problems is one of the main reasons behind their remarkable success among the general public. …”
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Designing a model for re-employment of employees during retirement (Study case: Ministry of Education) by Fatemeh Fatemeh Bina Baji, Hamid Rezaei Far, Mohammad Mohammadi, Monireh Salehnia

“…It is stated in the livelihood-oriented strategy that this strategy is written with this name due to the fact that it only solves the livelihood problems of retirees. The consequences of re-employment of education workers during retirement lead to improved performance and sustainable development. …”
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