Unveiling the hidden effect of multi-morbidities on the severity of Covid-19: a latent class analysis approach by Sedigheh Akhavnnezhad, Seyedeh Solmaz Talebi, Ehsan Mosa Farkhani, Marzieh Rohani-Rasaf

“…This approach will guide clinical decision-making and resource allocation in the ongoing management of the COVID-19 pandemic.…”
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Probabilistic Interference Prediction for Dynamic 6G In-X Sub-Networks by Pramesh Gautam, Carsten Bockelmann, Armin Dekorsy

“…Simulation results show that the proposed predictors outperform the baseline method in terms of coverage probability, with improvements ranging from 22–33% and 4–13% over VISPGPR for Bernoulli random and deterministic traffic, respectively. …”
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Age, frequency, and strategy optimization for organized colorectal cancer screening: a decision analysis conducted in China for the years 2023–2038 by Zixing Wang, Wei Han, Ran Fei, Yaoda Hu, Fang Xue, Wentao Gu, Cuihong Yang, Yubing Shen, Luwen Zhang, Jingmei Jiang

“…These findings should be valuable for policy-making regarding cancer control and resource allocation.…”
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Comparative Analysis of qSOFA, PRIEST, PAINT, and ISARIC4C Scores in Predicting Severe COVID-19 Outcomes Among Patients Aged over 75 Years by Daniela Rosca, Vamsi Krishna, Chandramouli Chetarajupalli, Adelina Maria Jianu, Ilona Emoke Deak, Claudia Raluca Balasa Virzob, Sorina Maria Denisa Laitin, Madalina Boruga, Rodica Lighezan

“…Results: Kaplan–Meier analysis indicated significantly lower survival probabilities for elderly patients with high scores at admission. …”
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Atezolizumab plus bevacizumab and chemotherapy as first-line therapy for cervical cancer: a cost-effectiveness analysis in the US by Yingtao Lin, Cijuan Li, Chang Wang, Jian Chen, Yuanqing Huang

“…Recently, numerous countries have mandated the pharmacoeconomic assessments of novel oncological agents to mitigate patient financial risks and optimize resource allocation. The present study evaluated the cost-effectiveness of adding atezolizumab to standard therapy (atezolizumab plus bevacizumab [BC]) for metastatic, persistent, and recurrent cervical cancer from the perspective of US healthcare payers, with the aim of supporting policymaking and promoting the rational use of healthcare resources.MethodsUsing clinical efficacy and safety data from the BEATcc clinical trial, in addition to cost and utility values from publicly available databases and published literature, a partitioned survival model over a 20-year lifetime horizon was developed to assess the cost-effectiveness of atezolizumab plus bevacizumab and chemotherapy (ABC) versus BC. …”
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Stability of symptom-based subtypes in Sjogren’s disease by Xavier Mariette, Jacques-Eric Gottenberg, Jessica Tarn, Wan-Fai Ng, Dennis Lendrem, John Casement, Joe Scott Berry, Kyle Thompson

“…In this study, we stratify patients longitudinally to understand how symptom-based subtypes vary over time and factors influencing subtype change.Methods 274 patients from the United Kingdom Primary Sjögren’s Syndrome Registry (UKPSSR) with data permitting NSST subtype assignment from two study visits were included. …”
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Calculation of risks of information security of telecommunication enterprise by L. M. Il’chenko, E. K. Bragina, I. E. Egorov, S. I. Zaysev

“…The result of this work was the calculation of information security risks, based on the allocation of valuable assets of the organization, the degree of potential damage in the implementation of threats to such assets and the probability of the implementation of threats to the information system of the telecommunication enterprise. …”
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A Privacy-Preserving Polymorphic Heterogeneous Security Architecture for Cloud–Edge Collaboration Industrial Control Systems by Yukun Niu, Xiaopeng Han, Chuan He, Yunfan Wang, Zhigang Cao, Ding Zhou

“…Comprehensive evaluations using natural gas pipeline pressure control and smart grid voltage control systems demonstrate superior performance: the proposed method achieves 100% system availability compared to 62.57% for static redundancy and 86.53% for moving target defense, maintains 99.98% availability even under common-mode attacks (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mn>10</mn><mrow><mo>−</mo><mn>2</mn></mrow></msup></semantics></math></inline-formula> probability), and consistently outperforms moving target defense methods integrated with state-of-the-art detection mechanisms (99.7790% and 99.6735% average availability when false data deviations from true values are 5% and 3%, respectively) across different attack detection scenarios, validating its effectiveness in defending against availability attacks and privacy leakage threats in cloud–edge collaboration environments.…”
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Cost–Utility Analysis of Multigene Assays to Guide Treatment Decisions for Node-Negative Early Breast Cancer by Vladislav Berdunov, Gebra Cuyún-Carter, Yaneth Gil-Rojas, Christy Russell, Sara Campbell, Jennifer Racz, Yara Abdou

“…This study aimed to estimate the cost-effectiveness of these four multigene assays compared with clinicopathologic risk assessment alone. Methods A decision tree categorized hypothetical patients with HR + /HER2− early-stage invasive breast cancer according to clinical and genomic risk, and integrated clinical expert insights for chemotherapy allocation with literature inputs. …”
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Leveraging large language models for automated detection of velopharyngeal dysfunction in patients with cleft palate by Myranda Uselton Shirk, Catherine Dang, Jaewoo Cho, Hanlin Chen, Lily Hofstetter, Jack Bijur, Claiborne Lucas, Andrew James, Ricardo-Torres Guzman, Andrea Hiller, Noah Alter, Amy Stone, Maria Powell, Matthew E. Pontell, Matthew E. Pontell

“…By providing a reliable pretest probability, the Whisper model can serve as a triaging mechanism to prioritize patients for further evaluation, reducing diagnostic delays and optimizing resource allocation.…”
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The Role of Gene of the Tumor Necrosis factor-alfa G-308A Polymorphism in the Development of Congestive Heart Failure in Patients with Ischemic Heart Disease and Obesity by Kravchun P., Kadykova O., Ryndina N., Krapivko S.

“…Materials and research methods. Within the research a complex examination of 222 patients with IHD and obesity has been performed. …”
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Analysis With Deep Learning of Robust UAV-Mounted Active IRS NOMA Networks With Imperfections by Chandan Kumar Singh, Deepak Kumar, Janne J. Lehtomaki, Zaheer Khan, Matti Latva-Aho, Prabhat K. Upadhyay

“…Our study advances complex optimization problems for deep neural network (DNN) hyperparameters, power allocation, and UAV positioning, which are crucial for the dynamic aerial communication environment. …”
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Cost-effectiveness analysis for implementation of smoking cessation strategies at primary health care settings in Tamil Nadu. by Vasantha Mahalingam, Ramesh Kumar Santhanakrishnan, Muniyandi Malaisamy, Karthick Chelvanayagam, Kavi Mathiyazhagan, Adhin Bhaskar, Karikalan Nagarajan, Jerard Maria Selvam, Surendran Veeraiah, Kavitha Rajsekar, Kirti Tyagi, Ponnuraja Chinnaiyan

“…<h4>Methods</h4>In this hypothetical cohort of 100,000 individuals using the decision tree analysis, a cost-effectiveness assessment was conducted for both proposed and existing strategies. …”
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Development and validation of an interpretable nomogram for predicting the risk of the prolonged postoperative length of stay for tuberculous spondylitis: a novel approach for risk... by Parhat Yasin, Haopeng Luan, Cong Peng, Xinghua Song

“…The calibration graphs showed that the expected and observed probability of prolonged PLOS was in close agreement. …”
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A world malaria map: Plasmodium falciparum endemicity in 2007. by Simon I Hay, Carlos A Guerra, Peter W Gething, Anand P Patil, Andrew J Tatem, Abdisalan M Noor, Caroline W Kabaria, Bui H Manh, Iqbal R F Elyazar, Simon Brooker, David L Smith, Rana A Moyeed, Robert W Snow

“…<h4>Background</h4>Efficient allocation of resources to intervene against malaria requires a detailed understanding of the contemporary spatial distribution of malaria risk. …”
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The prognostication of development of respiratory tract bacterial diseases for children of early age by H. O. Lezhenko, A. V. Abramov, H. V. Krainia

“…On the basis of the conducted factor analysis the most priority predictors of development of an acute pneumonia in children of early age with acute bronchopulmonary pathology who were further included to the mathematical prognostic model of probability of development of the specified disease were allocated.…”
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Patterns of West Nile virus vector co-occurrence and spatial overlap with human cases across Europe by Shirin Taheri, Mikel Alexander González, María José Ruiz-López, Ramón Soriguer, Jordi Figuerola

“…Identifying areas where highly competent vectors overlap with favourable environmental conditions is crucial for determining areas at risk for future WNV outbreaks.We analysed the distribution and habitat suitability of four Culex mosquito vectors across Europe using an ensemble of six modelling techniques and relevant environmental variables. We generated probability maps, converted them into binary distribution maps through threshold-based methods, and weighted them by WNV vector competence to identify hotspots of vector co-occurrence and human cases.Our findings indicate that WNV vectors are unevenly distributed across Europe, with southern regions emerging as hotspots, particularly due to the presence of highly competent vectors such as Culex univittatus s.l., Culex modestus, and Culex pipiens. …”
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Risk Assessment of Exposure to Chemical Pollutants in Industry Through the Development of a Hybrid Approach Based on Fuzzy Logic by Sadaf Jahangiri, Noushin Birjandi, Morteza Ghobadi

“…This method allows for more accurate and effective risk assessment by considering uncertainties and ambiguities in the data. …”
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Economic evaluation of short message service intervention for HIV prevention among men who have sex with men in China: a modelling study by Rui-Qi Fan, Jun-Tao Shu, Hao Huang, Ling-Yi Shi, Qi-Wei Ge, Xun Zhuang, Mei-Yin Zou, Gang Qin

“…The ICERs were most affected by the probability of HIV infection, intervention cost and coverage. …”
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Establishing the Median and 95% Effective Doses of Oliceridine for Immediate Post-Surgical Analgesia Following Laparoscopic Cholecystectomy: A Double-Blind, Sequential Dose-Finding... by Cao X, Xiao H, Yan H, Wei Y, Wen Q, Zhang Z, Xu G, Xu B, Chen J, Li X

“…Using Dixon and Massey’s up-and-down sequential allocation method, the median effective dose (ED50) and the dose required for 95% effective dose (ED95) were determined, alongside an evaluation of the agent’s safety profile.Methods: In this prospective trial, 82 participants scheduled for LC were enrolled and randomly assigned to receive either oliceridine or saline (control). …”
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