Effectiveness of a brief group behavioural intervention on psychological distress in young adolescent Syrian refugees: A randomised controlled trial. by Richard A Bryant, Aiysha Malik, Ibrahim Said Aqel, Maha Ghatasheh, Rand Habashneh, Katie S Dawson, Sarah Watts, Mark J D Jordans, Felicity L Brown, Mark van Ommeren, Aemal Akhtar

“…This study evaluated the effectiveness of a nonspecialist delivered group-based intervention (Early Adolescent Skills for Emotions (EASE)) to improve young adolescents' mental health.<h4>Methods and findings</h4>In this single-blind, parallel, controlled trial, Syrian refugees aged 10 to 14 years in Jordan were identified through screening of psychological distress as defined by scores ≥15 on the Paediatric Symptom Scale. …”
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The OPTION trial: outpatient induction of labour – study protocol for a prospective, non-inferiority, multicentre randomised controlled trial by Kristina Gemzell-Danielsson, Susanne Hesselman, Sophia Brismar Wendel, Magnus Domellöf, Ulla-Britt Wennerholm, Maria Jonsson, Verena Sengpiel, Helen Elden, Ylva Carlsson, Sofie Graner, Tove Wallström, Helena Kopp-Kallner, Heléne Sangskär, Andreas Herbst

“…Before introducing outpatient induction into clinical routine, studies need to assure safety for the child and woman as well as efficacy of the method.Method and analysis A register-based randomised controlled multicentre non-inferiority trial to study if outpatient induction in low-risk inductions is (1) as safe for the child (perinatal composite of mortality and morbidity) and (2) as effective (proportion of vaginal deliveries) as inpatient induction at the hospital. …”
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Development and validation of a nomogram for predicting low bone mineral density in male patients with ankylosing spondylitis by Xiaotong Yang, Qin Cheng, Yifan Li, Hao Tang, Hao Tang, Xin Chen, Lijun Ma, Jing Gao, Wei Ji

“…ObjectiveThis retrospective cohort study aimed to develop and validate clinical nomogram models for predicting site-specific low bone mineral density (BMD) risk in male patients with ankylosing spondylitis (AS).MethodsThis study enrolled male AS patients treated at the Rheumatology Department of Jiangsu Provincial Hospital of Traditional Chinese Medicine between January 2017 and September 2024. …”
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Clinical and cost-effectiveness of percutaneous nephrolithotomy, flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole stones: the PUrE RCTs by Oliver Wiseman, Daron Smith, Kath Starr, Lorna Aucott, Rodolfo Hernández, Ruth Thomas, Steven MacLennan, Charles Terry Clark, Graeme MacLennan, Dawn McRae, Victoria Bell, Seonaidh Cotton, Zara Gall, Ben Turney, Samuel McClinton

“…PCNL is highly likely to be cost-effective at the usual cost-effectiveness threshold values used for decision-making in the UK NHS (e.g. probability of 0.87 at £20,000 per QALY gained). These results, however, are dependent on the method used to estimate the costs of the initial interventions. …”
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Estimating Lifetime Risk of Autosomal Recessive Kidney Diseases Using Population-Based Genotypic Data by Matthias Christoph Braunisch, Clara M. Großewinkelmann, Martin Menke, Nora Hannane, Riccardo Berutti, Jasmina Ćomić, Roman Günthner, Lutz Renders, Christoph Schmaderer, Uwe Heemann, Korbinian M. Riedhammer, Matias Wagner, Julia Hoefele

“…Conclusion: This study offers a comprehensive population-genetic assessment of the lifetime risk associated with ARKDs focusing on European populations, shedding light on previously underestimated prevalences and diagnostic probabilities. Consequently, these findings provide crucial insights for optimizing resource allocation towards therapy development, enhancing public health strategies, and guiding future biomedical research endeavors.…”
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Sex-based disparities in liver transplantation: Evidence from a nationwide Italian cohort by Chiara Becchetti, Silvia Trapani, Lucia Masiero, Silvia Testa, Francesca D’Arcangelo, Lucia Lapenna, Manuela Merli, Valentina Cossiga, Maria Guarino, Filomena Morisco, Marta Cilla, Federica Invernizzi, Elisabetta Cerutti, Pierluigi Toniutto, Francesca Puoti, Massimo Cardillo, Giuseppe Feltrin, Patrizia Burra

“…Background &amp; Aims: Although sex-based disparities in the liver transplantation (LT) setting have been acknowledged for several years, particularly by studies conducted in the USA, data from European countries are scarce. Methods: We conducted a nationwide, retrospective, observational study on candidates identified for LT in Italy between January 2017 and December 2021 using national registry data with follow-up until June 2023. …”
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Bayesian Analysis of Time-To-Event Data in a Cluster-Randomized Trial: Major Outcomes With Personalized Dialysate TEMPerature (MyTEMP) Trial by Yongdong Ouyang, Bin Luo, Stephanie N. Dixon, Ahmed A. Al-Jaishi, P.J. Devereaux, Michael Walsh, Ron Wald, Merrick Zwarenstein, Sierra Anderson, Amit X. Garg

“…Limitations: The interpretation of Bayesian methods highly depends on the prior distributions. …”
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Uncertain edge coalition game based EIP revenue estimation strategy by ZHAO Shuxu, XIA Xinyu, WANG Xiaolong

“…In the edge computing environment, there are risks such as communication channel risks and edge server failures, which can lead to a mismatch between the computing resources required for task processing and the resources allocated by the edge coalition. In response, a revenue forecasting method for the edge coalition and its member edge infrastructure provider (EIP) based on the game theory of uncertain coalition structures was proposed. …”
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The Moderating Effect of Financial Constraint on the Relationship between Economic Policy Uncertainty and Corporate Financialization by Vahid Taghizadeh Khanqah, Younes Badavar Nahandi

“…The independent variable in this study was economic policy uncertainty defined as a situation in which the probabilities of future events are indeterminate; even when potential events are known, their associated probabilities remain uncertain. …”
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Symbiosis effects of Mycorrhizal and Pseudomonas on morphophysiological traits of mung bean (Vigna radiata (L.) Wilczek) under moisture stressed condition by Mohammad Salehi, Ali Faramarzi, Manochehr Farboodi, Nasser Mohebalipour, Jalil Ajalli

“…The main factors allocated to three levels of drought stress included: normal irrigation (control), stopping irrigation in flowering stage, stopping irrigation in pods formation stage. …”
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Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial by Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson

“…If female and of child-bearing potential, a negative urine β-hCG test and using a highly effective contraceptive method. Willing and able to confirm written informed consent at the point of randomisation. …”
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Prediction of metastatic risk of renal clear cell carcinoma based on CT radiomics analysis by Xueyi Wang, Youchang Yang, Jiaojiao Wu, Xiaoqiang Tang, Yao Wang

“…ObjectiveTo investigate the value of using imaging histological models to non-invasively assess the risk of metastasis in patients with clear cell renal cell carcinoma (ccRCC).MethodsThis study retrospectively enrolled 273 clear cell renal cell carcinoma (ccRCC) patients from three hospitals, with 57 cases allocated as an independent test cohort. …”
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Identification and validation of clinical phenotypes in Staphylococcus aureus blood stream infection and their association with mortality (FEN-AUREUS cohort-based study)Research in... by Belén Gutiérrez-Gutiérrez, Belén Gallego-Mesa, Achim J. Kaasch, Matthias Riediger, Siegbert Rieg, Marta Trigo, Sonsoles Salto-Alejandre, Francisco Anguita-Santos, Ángela Cano, Andrea Prolo-Acosta, Salvador López-Cárdenas, María Teresa Pérez-Rodríguez, Francisco Javier Martínez-Marcos, Esperanza Merino-Lucas, Blanca Anaya-Baz, Ana Arizcorreta, Antonio Plata-Ciézar, Marco Piscaglia, Alexandra Aceituno, Lidia Romero-Calderón, Daniel Hornuss, Aurora Alemán-Rodríguez, Adelina Gimeno-Gascón, Esther Recacha, Julián Torre-Cisneros, Nicolás Merchante, Álvaro Pascual, Luis Eduardo López-Cortés, Jesús Rodríguez-Baño

“…The aim of the study was to identify clinical phenotypes among patients with SAB, to evaluate their association with mortality, and to derive and validate a simplified probabilistic model for phenotypes assignment. Methods: Phenotypes were derived using two-stage cluster analysis of 2128 patients from the ISAC cohort (recruited between 2013 and 2015), analysing 62 variables. …”
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A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT by Nusrat Husain, Karina Lovell, Carolyn A Chew-Graham, Farah Lunat, Penny Bee, Matthias Pierce, Najia Atif, Saadia Aseem, Kamaldeep Bhui, Peter Bower, Traolach Brugha, Nasim Chaudhry, Akbar Ullah, Linda Davies, Nadeem Gire, Deepali Sharma, Jahanara Miah, Waqas Ahmed, Joe Kai, Ilyas Mirza, Jillian Morrison, Naeem Mohmed, Atif Rahman, Shanaya Rathod, Najma Siddiqi, Waquas Waheed, Christopher Williams, Nosheen Zaidi, Richard Emsley, Richard Morriss

“…This study has led to multidisciplinary deliberations on a broader level across the UK, focusing on the culturally adapted method of engagement and delivery tailored explicitly for ‘hard-to-reach’ communities. …”
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Incidence of SUDEP in a cohort of patients with refractory epilepsy: the role of surgery and lesion localization by Andrea Garcia de Almeida, Magda Lahorgue Nunes, André Luis Fernandes Palmini, Jaderson Costa da Costa

“…Patients were allocated in two groups (operated and non operated). …”
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DESIGN, DEVELOPMENT AND IMPLEMENTATION OF A RISK MANAGEMENT MODEL ADAPTED TO PROJECTS CARRIED OUT WITH EUROPEAN FUNDING by Robert-Anton V. ION, Dorina Nicoleta MOCUȚA

“…In this context, but also based on that a significant benefit is considered to have the best possible results with limited resources, we aimed to focus on the economic events in the area of grants allocated to Romania through the European Structural and Investment Funds and to approach the chosen topic, understanding that, probably, the most important challenge for the next period will be for potential beneficiaries to identify and subsequently position themselves in an environment characterized by a balance between risk, cost and added value, which will certainly no longer be achievable without a clear determination of the main key risks they may face during the steps required to carry out an investment project, as well as the measures to mitigate any adverse effects resulting from the occurrence of the risks.…”
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A study on the convergence of lean and green management goals by Larinina Tatyana, Djoldosheva Tamara, Mottaeva Asiiat

“…Goal setting determines the transformation of production management methods and approaches. Real practice often differentiates Lean and Green approaches. …”
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BEHAVIORAL EFFECTS OF ARONIA MELANOCARPAFRUIT JUICE IN EXPERIMENTAL ANIMALS WITH DIET-INDUCED METABOLIC SYNDROME by M. Abtulov, M. Eftimov, S. Marinova, M. Salbashian, M. Zhelyazkova-Savova, S. Valcheva-Kuzmanova

“…PURPOSE: This study evaluated the effects of polyphenol-rich Aronia melanocarpafruit juice (AMFJ) on the behavior of rats with metabolic syndrome (MS)induced by high-fat high-fructose diet. METHODS: Fifty rats were allocated into 5 groups (10 rats per group): control, MS, MS + AMFJ2.5, MS + AMFJ5and MS + AMFJ10. …”
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Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…Feedback from patients and carers The process evaluation used a mixed-methods approach to obtain participant feedback about optimising transition support and to understand factors influencing engagement with ECHOMANTRA intervention. …”
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Prediction of KRAS gene mutations in colorectal cancer using a CT-based radiomic model by Wenjing Wang, Qingbiao Zhang, Shimei Fan, Yuyin Wang, Xingyan Le, Min Ai, Chunqi Du, Junbang Feng, Chuanming Li

“…This study aimed to explore the clinical value of radiomics models based on CT images in predicting the KRAS mutation status in patients with CRC.MethodsA total of 201 CRC patients who underwent surgery and pathology examinations from March 2022 to January 2025 were included. …”
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