Comparison of Metabolite Changes in Lycium barbarum Bud Tea at Different Processing Stages by Widely Targeted Metabolomics by WEI Jiayi, MI Jia, ZHANG Bo, WANG Siyu, GE Xinyu, JIN Bo, LUO Qing, ZHANG Lutao, LU Lu, YAN Yamei

“…These differential metabolites were predominantly enriched in metabolic pathways such as purine metabolism, niacin and nicotinamide metabolism, cysteine and methionine metabolism, and a small proportion of them was enriched in pathways like zeeatin biosynthesis, and ABC transporter. Significant differences were observed in inosine, homocysteine, cinnamic acid, 4-hydroxy-3-methoxycinnamic acid, and isoferulic acid among processing stages, indicating their involvement in the quality formation of L. barbarum bud tea during processing. …”
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Unveiling immune cell response disparities in human primary cancer-associated fibroblasts between two- and three-dimensional cultures. by Jian-Ping Yang, Nikhil Nitin Kulkarni, Masashi Yamaji, Tsubasa Shiraishi, Thang Pham, Han Do, Nicole Aiello, Michael Shaw, Toshihiro Nakamura, Akiko Abiru, Narender R Gavva, Shane R Horman

“…In this study, we investigated the effects of 2D and 3D culturing conditions on human primary CAFs integrated into a modular tumor microenvironment (TME). …”
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Household Income and Educational Completional Rates of Girl Child in Primary Schools of Kamuganguzi Sub-County Kabale District Uganda. by Ainembabazi, Babrah

“…There was a clear relationship between household income and educational completion rates, with factors like increased enrollment, gender gaps, student sustainability, and access to necessary services being significant. …”
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How does QI work? A trust-building framework in African healthcare: primary evidence from Kenya and Malawi by Mary B Adam, Kedar Mate, Naomi Wambui Makobu, Tod Newman, Angela Joy Donelson

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Positive selection in bone morphogenetic protein 15 targets a natural mutation associated with primary ovarian insufficiency in human. by Sylvain Auclair, Raffaella Rossetti, Camille Meslin, Olivier Monestier, Elisa Di Pasquale, Géraldine Pascal, Luca Persani, Stéphane Fabre

“…Bone Morphogenetic Protein 15 (BMP15) is a TGFβ-like oocyte-derived growth factor involved in ovarian folliculogenesis as a critical regulator of many granulosa cell processes. …”
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Obesity and its association with ultra-processed food consumption in older adults in Roraima, Brazil by Gabriela Rocha dos Santos, Guilherme José Silva Ribeiro, Mateus Augusto Bim, Clair Costa Miranda, Andreia Pelegrini, André de Araújo Pinto

“…Objective: To estimate the prevalence of obesity and analyze its association with the consumption of ultra-processed foods (UPF) among older adults in primary health care. …”
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Are Artificial Intelligence Models Listening Like Cardiologists? Bridging the Gap Between Artificial Intelligence and Clinical Reasoning in Heart-Sound Classification Using Explain... by Sami Alrabie, Ahmed Barnawi

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Sex Disparities in Diabetes Process of Care Measures and Self-Care in High-Risk Patients by Margaret K. Yu, Courtney Rees Lyles, Luis A. Bent-Shaw, Bessie A. Young

“…Sex differences in processes of care and self-care activities were assessed in a cross-sectional analysis of the Pathways Study, an observational cohort of primary care diabetic patients from a managed care organization (N=4,839). …”
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Protein oxidation and its effect on functional properties of livestock products during the processing and storage: A review by Jiamei Wang, Na Wu, Yao Yao, Shuping Chen, Lilan Xu, Yan Zhao, Yonggang Tu

“…It is governed by two primary mechanisms: the direct oxidation by active entities and the indirect oxidation by secondary oxidation byproducts like lipid oxidation, influenced by many factors. …”
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Stabilization and Solidification of Produced Tailings in the Lead Extraction Process Using Brine Leaching Method by Ravanbakhsh Shirdam, Atefeh Nezami

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Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2) by Adam W A Geraghty, Taeko Becque, Lisa C Roberts, Jonathan Hill, Nadine E Foster, Lucy Yardley, Beth Stuart, David A Turner, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Stephanie Hughes, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Gemma Mansell, Malcolm White, Firoza Davies, Paul Little

“…Our health economic analysis showed that both interventions were likely to be cost-effective compared to the usual primary care alone group. …”
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Case Report: A case of neuropsychiatric lupus with primary central nervous system diffuse large B-cell lymphoma by Yuexi Zhang, Shaoling Zheng, Yiming Li, Shuyang Chen, Xin Guo, Zhixiang Huang, Weiming Deng, Yuheng Xing, Zhengping Huang, Tianwang Li, Tianwang Li

“…BackgroundThe coexistence of neuropsychiatric systemic lupus erythematosus (NPSLE) and primary diffuse large B-cell lymphoma (DLBCL) of the central nervous system (CNS) (PCNS DLBCL) is extremely rare in clinical practice. …”
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Emotion and Stress Related Eating and Personality Dimensions Predict Food Addiction: Implications for Personalized Weight Management and Primary Prevention by Eva Klanduchova, Lucia Adamovska

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The effects of ozone pretreatment on the physicochemical, functional, bioactive, textural, and sensory properties of medicinal plants: A comprehensive review by Zahra Shafiee, Bahram Hosseinzadeh Samani

“…Nevertheless, research on the effects of ozone on functional and bioactive compounds of food and medicinal plants is still ongoing since it will be the basis for its establishment as a new technique. Conclusion: The primary objectives achieved by applying ozone technology include maintaining and enhancing quality, improving antimicrobial efficiency, reducing chemical usage, environmental sustainability, and developing new processing methods. …”
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IL-4Rα-associated antigen processing by B cells promotes immunity in Nippostrongylus brasiliensis infection. by William G C Horsnell, Matthew G Darby, Jennifer C Hoving, Natalie Nieuwenhuizen, Henry J McSorley, Hlumani Ndlovu, Saeeda Bobat, Matti Kimberg, Frank Kirstein, Anthony J Cutler, Benjamin Dewals, Adam F Cunningham, Frank Brombacher

“…Furthermore, the rapid nature of these protective effects by B cells suggested non-BCR mediated mechanisms, such as via Toll Like Receptors, was involved, and this was supported by transfer experiments using antigen pulsed Myd88⁻/⁻ B cells. …”
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Educationional health for pregnant women using the group strategy by Camila Teixeira Moreira Vasconcelos, Maria de Fátima Antero Sousa Machado, Samélia Léa Menezes Becker

“…Among the several tools available to the primary health care professionals, the group strategy has been very encouraged and pregnancy has been a unique opportunity for the implementation of educational actions like these. …”
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Dissipative processes in 18O + 9Be and 18O + 181Ta reactions at Fermi energies by B. Erdemchimeg, T. I. Mikhailova, A. G. Artyukh, G. Kaminski, Yu. M. Sereda, M. Colonna, M. Di Toro, H. H. Wolter

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A comprehensive analysis of process-related CO2 emissions from Iran's cement industry by Bahman Massoumi Nejad, Sara Enferadi, Robbie Andrew

“…The findings show notable geographical variations and a substantial national trend, with emissions rising from 28.75 million tonnes (Mt) in 2016 to 39.33 Mt in 2023. A primary contributor is Iran's high clinker-to-cement ratio, averaging 94.1% in 2023, underscoring the urgent need for sustainable production practices, particularly through the adoption of supplementary cementitious materials (SCMs) like pozzolans and industrial by-products. …”
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Evaluation of microstructure and mechanical properties resulting from gas nitriding process for different types of steel by Faras Q. Mohammed, Ibrahim Abd L-Kareem Ahmed, Sameer Khalaf Fyayyadh

“…SEM and X-ray diffraction tests were performed to assess the microstructural features and the primary phases formed after surface treatment. The new secondary precipitates were identified as γ′-Fe4N, ε (Fe2–3N), and α-Fe, exhibiting an uneven chain-like pattern within columnar grains. …”
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Task shifting from general practitioners to nurses in out-of-hours primary care: an explorative case study of team-based practices by Katrine Bjørnshave Bomholt, Anna Mygind, Mette Amalie Nebsbjerg, Morten Bondo Christensen, Linda Huibers, Viola Burau

“…Background Out-of-hours primary care (OOH-PC) is essential for treating urgent health problems. …”
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