Global prevalence of antidepressant drug utilization in the community: protocol for a systematic review by Annie Leblanc, Stéphane Turcotte, Elisabetta Poluzzi, Becky Skidmore, Michèle Dugas, Patrick Blouin, Marie-Pier Déry, Carlotta Lunghi, Jacinthe Leclerc, Cathy Martineau, Valérie Carnovale, Théo Stéfan, Johanie Lépine, Laura Jalbert, Olha Svyntozelska, Giraud Ekanmian, Daniele Maria Nogueira, Pelumi Samuel Akinola

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Structural insights into PKS13 Thioesterase inhibitors targeting Mycobacterium tuberculosis for drug-resistant tuberculosis therapy: Identification, stability assessment, and pharm... by Zia Ur Rehman, Hassan A. Alhazmi, Mohammed Albratty, Abdullah Algaissi, Hafiz A. Makeen, Asim Najmi, Khalid Zoghebi, Sivakumar S. Moni, Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Asaad Khalid, Magbool Essa Oraiby, Ibrahim Ahmed Bokar

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Mapping the Epidemiologic Features of Endotracheal Tube ObstructionTake-Home Points by Vimal Bhardwaj, MD, FNB(Critical Care), EDIC, Abhishek Samprathi, MD, DrNB, EDIC, Manu M.K. Varma, MD, DM, Kingshuk Saha, MSc, Ross Prager, MD, John Basmaji, MD, Nicolas Orozco, MD, Srirang Ramamoorthy, MSc, Jose Chacko, MD, EDIC, Arjun Alva, MD

“…In the CICU, severe ETBs was observed in < 2% of patients, compared with 4% of patients in the MICU, whereas moderate ETBs were present in 27.9% of patients in the CICU and 16.5% of patients in the MICU. …”
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Impacts of dietary Saccharomyces cerevisiae fermentation derived postbiotic on growth performance and health status of Pacific white shrimp by Elangovan Prabu, Nathan Felix, Victor L. Nsereko, Jarin Sawanboonchun, Arumugam Uma, Govindharaj Sathishkumar, Pushparaj Chidambaram, Thangaraju Thiruvasagam, Krishnan Ravaneswaran

“…By improving disease resistance and gut health, SCFP could help minimize the need for antibiotics, potentially reducing the chances of antimicrobial resistance development and contributing to more sustainable and eco-friendly shrimp farming practices.…”
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Mapping wheat potential: a GIS-based agro-land suitability analysis in Gujarat’s Bhal Region, Western India by Ranjan Kumar, Subhankar Ghosh, Gautam R. Patel, Laishram Kanta Singh, Amulya Kumar Mohanty, Arun Kumar Singha

“…By addressing the challenges of crop selection and resource optimization, these findings contribute to ensuring food security and promoting sustainable agricultural practices in the region.…”
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Structural and political determinants of health among Syrian refugee young adults in the Bekaa, Lebanon: a prospective cohort study of the impact of security raids on perceived dis... by Rima A Afifi, Rima Nakkash, Malak Tleis, Lilian Ghandour, Grant Brown, Hanan Al Masri, Marwa Fares, Fadi Al Halabi, Yamen Najjar, Bayan Louis

“…Objectives In this work, which forms part of a larger study of a longitudinal intervention focused on empowering Community Mental Health Workers in a humanitarian context, we examine changes in and correlates of well-being of refugees as a result of discriminatory practices by the State, with comparisons motivated by a mechanistic model of well-being.Design This cohort study examines well-being at a single follow-up time as predicted by baseline characteristics in response to a changing social conditions including security raids on our participants; the parent interventional randomised trial focuses on a population of youth in a refugee context, but the present work precedes the main intervention period.Setting Refugee populations are among the most vulnerable globally, and the total refugee population is growing dramatically. …”
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The implementation of safer drug consumption facilities in Scotland: a mixed methods needs assessment and feasibility study for the city of Edinburgh by James Nicholls, Wendy Masterton, Danilo Falzon, Andrew McAuley, Hannah Carver, Kathryn Skivington, Josh Dumbrell, Andy Perkins, Samantha Steele, Kirsten Trayner, Tessa Parkes

“…In response to concerns about drug-related harms in Edinburgh, elected officials have considered introducing SDCFs in the city. This paper presents key findings from a feasibility study commissioned by City of Edinburgh Council to support these deliberations. …”
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Synergistic AI-resident approach achieves superior diagnostic accuracy in tertiary ophthalmic care for glaucoma and retinal disease by Dalia Camacho-García-Formentí, Gabriela Baylón-Vázquez, Karen Arriozola-Rodríguez, Enrique Avalos-Ramirez, Curt Hartleben-Matkin, Hugo Valdez-Flores, Damaris Hodelin-Fuentes, Alejandro Noriega

“…The synergistic use of AI and resident assessments showed potential for optimizing diagnostic accuracy, highlighting the value of AI as a supportive tool in ophthalmic practice, especially for early career clinicians.…”
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Differential Diagnostic Indicators for the Appointment of Non-Steroidal Anti-Inflammatory Therapy in the Treatment of Red Eye Syndrome at the Stage of Primary Outpatient Admission.... by V. N. Trubilin, E. G. Poluninа, A. A. Kozhukhov, V. V. Kurenkov, N. V. Moreva, A. V. Trubilin, K. V. Chinenova

“…The above algorithm will be presented in the second part of this article.…”
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Descemet Endothelial Thickness Comparison Trial 1 (DETECT 1): outcome masked, placebo-controlled trial comparing two types of corneal transplant surgeries and effect of rho kinase... by Thomas M Lietman, Jennifer Rose-Nussbaumer, Bennie H Jeng, Benjamin F Arnold, Winston Chamberlain, Charles C Lin, Jennifer Y Li, William Gensheimer, Jameson Clover, Nicole Varnado, Sarah Abdelrahman

“…Adjuvant ripasudil, a rho kinase inhibitor, may address the challenge of ECL in corneal transplantation. This paper presents the protocol for the Descemet Endothelial Thickness Comparison Trial 1 (DETECT 1), a multicentre, outcome-masked, randomised, placebo-controlled, four-arm clinical trial.Methods A total of 160 eligible patients with endothelial dysfunction will be enrolled from five participating sites in the USA. …”
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Association between alpha-1-acid glycoprotein and frailty in US females aged 20–49 years: analysis of NHANES data (2015–2023) by Yaru Liu, Yunxun Chen, Lijuan Zhou, Yantao Yin, Yuqiong Cao, Guang Li, Tian Xu, Xianxiu Wen

“…Abstract As a significant global health issue, frailty has important implications for clinical practice and public health. Systemic inflammation has been identified as an important mechanism influencing the development of frailty. …”
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Evaluating and Optimizing MySejahtera App Analytics for Sustainable Digital Government Services by Adawiyah Ashar, Nur Fazidah Elias, Ruzzakiah Jenal, Meng Chun Lam, Maheshwara Rao Appannan, Siti Aishah Iskandar

“…Through the implementation of both statistical and thematic analyses, this study presents critical factors that affect the app&#x2019;s sustainability and its effectiveness within the realm of Malaysia digital governmental services. …”
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A stepped wedge cluster randomized implementation trial to increase outpatient management of low-risk pulmonary embolism from the emergency department – the MEDIC ALERT PE study by Shawna N. Smith, Colin F. Greineder, Joshua Errickson, Jessica Burns, F Jacob Seagull, Keith E. Kocher, Jeffrey A. Kline, Jeffrey T. Kullgren, Michael S. M. Lanham, Sarah L. Krein, Geoffrey D. Barnes

“…Abstract Background Home-based care for patients diagnosed in emergency departments (EDs) with low-risk pulmonary embolism (PE) is an evidence-based, guideline-recommended practice that is not widely adopted in the US. Few studies demonstrate how this care pathway can be implemented effectively or test whether implementation strategies can address known barriers. …”
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How air pollution fuels respiratory infections in children: current insights by Susanna Esposito, Valentina Fainardi, Annachiara Titolo, Angela Lazzara, Marialaura Menzella, Beatrice Campana, Alberto Argentiero, Nicola Principi

“…Results of these key researches can be translate into clinical and public health practice capable to help protect and improve children’s environmental health.…”
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Interpretable noninvasive diagnosis of tuberculous pleural effusion using LGBM and SHAP: development and clinical application of a machine learning model by Bihua Yao, Xingyu Yu, Liannv Qiu, Er-min Gu, Siyu Mao, Lei Jiang, Jijun Tong, Jianguo Wu

“…Background Tuberculous pleural effusion (TPE) is a prevalent tuberculosis complication, with diagnosis presenting considerable challenges. Timely and precise identification of TPE is vital for effective patient management and prognosis, yet existing diagnostic methods tend to be invasive, lengthy, and often lack sufficient accuracy. …”
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‘Time is of the essence’: upper-body aerobic exercise to improve cardiovascular health during inpatient rehabilitation within the first year following spinal cord injury – protocol... by Samuel J E Lucas, Tom E Nightingale, Naveen Kumar, Shin-Yi Chiou, Afroditi Stathi, Manish Kalla, Daniel D Hodgkiss, Shane J T Balthazaar, Aheed E F Osman, Srinivasa C Budithi, Joy Roy Chowdhury

“…Outcome data will be presented at international conferences, patient advocacy groups, health professional networks and community health events. …”
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Guided self-determination intervention versus attention control for people with type 2 diabetes in outpatient clinics: a protocol for a randomised clinical trial by Christian Gluud, Jane Lindschou, Thordis Thomsen, Janus C Jakobsen, Vibeke Zoffmann, Anne Sophie Mathiesen, Tine Bruhn Skytte, Bodil Rasmussen, Emilie Marqvorsen, Mette Rothmann

“…The results of the trial will be presented at the outpatient clinics treating people with type 2 diabetes, at national and international conferences as well as to associations for people with diabetes and their relatives.Trial registration number ClinicalTrials.gov identifier: NCT04601311.…”
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Towards a Crowdsourced Digital Coffee Atlas for Sustainable Coffee Farming by Emma Krischkowsky, Onur Bal, Colin Beyer, David Miller, Manuel Walter, Kirstin Kohler

“…The present work summarizes the results of a 15-week student project addressing the field of sustainable coffee farming. …”
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Age- and sex-specific reference values for CT-based low skeletal muscle quantity and quality in healthy living kidney donors by David Martin, Paola Dolce, Martin Hübner, Tobias Zingg, David Fuks, Jean-Pierre Venetz, Damien Maier, Maurice Matter, Fabio Becce

“…Correlations were all weak for SMRA (creatinine: r = 0.220, p &lt; 0.001; 24h-UCE: r = 0.177, p = 0.006) and IMATI (creatinine: r = −0.101, p = 0.054; 24h-UCE, r = −0.108, p = 0.093).ConclusionThe age- and sex-specific reference values reported here could be used in clinical practice and future studies to identify patients at risk of muscle decline.…”
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Accuracy, inter‐ and intrarater reliability, and user‐experience of high tibial osteotomy angle measurements for preoperative planning: manual planning PACS versus semi‐automatic s... by Iris E. W. G. Laven, Femke F. Schröder, Feike deGraaff, J. Christiaan Rompen, Roy A. G. Hoogeslag, Albert H. vanHouten

“…However, both software programs provide similar performance after remeasurement of the human‐related erroneous outliers. For clinical practice, both programs can be utilised for HTO planning. …”
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