A multicenter study to evaluate the analytical precision by pathologists using the Aperio GT 450 DX by Thomas W. Bauer, Matthew G. Hanna, Kelly D. Smith, S. Joseph Sirintrapun, Meera R. Hameed, Deepti Reddi, Bernard S. Chang, Orly Ardon, Xiaozhi Zhou, Jenny V. Lewis, Shubham Dayal, Joseph Chiweshe, David Ferber, Aysegul Ergin Sutcu, Michael White

“…Background: Digital pathology systems (DPS) are emerging as capable technologies for clinical practice. Studies have analyzed pathologists' diagnostic concordance by comparing reviews of whole slide images (WSIs) to glass slides (e.g., accuracy). …”
Get full text

Implementation of C-reactive protein point of care testing to improve antibiotic targeting in respiratory illness in Vietnamese primary care (ICAT): a study protocol for a cluster... by H Rogier van Doorn, Behzad Nadjm, Yoel Lubell, Rachel Claire Greer, Sabine Dittrich, Sonia Lewycka, Nga Thi Thuy Do, Maida Vandendorpe, Van Anh Nguyen, Pham Ngoc Thach, Ta Thi Dieu Ngan, Nguyen Van Kinh, Cao Hung Thai, Le Thi Kim Dung, Tu Nguyen Thi Cam, Thanh Ha Nguyen

“…Introduction C-reactive protein (CRP), a biomarker of infection, has been used widely in high-income settings to guide antibiotic treatment in patients presenting with respiratory illnesses in primary care. …”
Get full text

Breast Milk Metabolomic Profile Is Associated With Maternal Overweight/Obesity Status or Adherence to Mediterranean Diet and Infant Weight Gain During the First Month of Lactation by Catalina A. Pomar, Petr Zouhar, María DeLucas, Tomas Cajka, Pilar Cobo, María Victoria Jiménez‐Cabanillas, Pere Bibiloni, Jan Kopecky, Andreu Palou, Francisca Serra, Juana Sánchez, Catalina Picó

“…None of the metabolites identified remained statistically significant after multiple‐comparisons adjustment. Present results, showing how maternal diet and obesity can affect breast milk metabolites and infant growth, offer insights to improve lactation‐feeding practices and support healthy infant development.…”
Get full text

The relationship between intraosseous catheter tip placement, flow rates, and infusion pressures in a high bone density cadaveric swine (Sus scrofa) model by Joseph A. Gehrz, Victoria C. Kay, Derek W. Grady, Alec D. Emerling, Andrew McGowan, Erin R. Reilly, Vikhyat S. Bebarta, Joshua Nassiri, Jorge Viñals, Gregory J. Zarow, Jonathan D. Auten

“…Conclusion Within the limitations of an unpressurized cadaveric swine model, the present findings suggest that IO catheter tip placements need not be perfect to acquire high flow rates at low pressures, only accurate enough to avoid the dense cortical bone of zone 3. …”
Get full text

Educación Física y ciudadanía: una revisión interpretativa crítica (Physical Education and citizenship: a critical interpretive review) by Mario Fuentes, Carmen Trigueros Cervantes, Alberto Moreno Doña

“…Abstract. This article presents an interpretative review of the relationship between the subject of Physical Education and the development of citizenship in a school context. …”
Get full text

Implications of No Tail Docking on Performance, Health, and Behavior of Pigs Raised Under Commercial Conditions in Brazil by Juliana Cristina Rego Ribas, Joseph Kaled Grajales-Cedeño, Isadora Gianeis, Vivian S. Sobral, Mateus José Rodrigues Paranhos da Costa

“…In conclusion, managing piglets with intact tails on commercial farms presents a significant welfare challenge. By contrast, docking the final third of the tail, in accordance with regulations, was associated with fewer negative welfare outcomes, even when best management practices were applied.…”
Get full text

The use of various genetically engineered biological drugs and selective immunosuppressants within the current provider-payment model of russian diagnosis-related groups by E. V. Derkach, E. A. Pyadushkina, M. V. Avxentyeva, T. V. Boyarskaya, E. E. Yagnenkova, A. S. Mokrova, M. M. Maryanyan

“…Still, the results of the present study indicate the necessity in the optimization of the system of payment for medical care with genetically-engineered biologic drugs and selective immunodepressants through the implementation of a differentiated approach to the payment at the federal level.…”
Get full text

Reducing scheduled evening training does not improve recruits' sleep duration or quality during British Army basic training by Alex J. Rawcliffe, Bethany Moxham, Harry Britt, Katrina Hinde, Shaun Chapman, Andrew Roberts

“…Sleep-wake data are presented descriptively (mean ± SD) and a series of linear-mixed models determined differences in actigraphy between groups and across each week.ResultsCompared to CMS18, no significant improvements in any sleep-wake indices were observed during CMS21. …”
Get full text

IMMUNOLOGICAL MARKERS OF UNCONTROLLED ATOPIC BRONCHIAL ASTHMA IN CHILDREN by M. V. Smolnikova, S. V. Smirnova, N. A. Ilyenkova, O. S. Konopleva

“…A group of Caucasian (European) children was involved into the research: Cohort 1, moderate atopic  bronchial asthma with controlled course during the last 3 months (n = 59); Cohort 2, severe/moderate-severe atopic bronchial asthma with uncontrolled course of the disease within last 3 months (n = 51),  Cohort 3 – control, practically healthy  children without signs of atopy  (n = 33). …”
Get full text

Patient-reported outcome measures for systemic lupus erythematosus: an expert Delphi consensus to guide implementation in routine care by Isabel Castrejón, Laura Cano, María José Cuadrado, Joaquín Borrás, Maria Galindo, Tarek C. Salman-Monte, Carlos Amorós, Carmen San Román, Isabel Cabezas, Marta Comellas, Alejandro Muñoz

“…PROMs most frequently used in clinical practice are pain (56%), patient’s global assessment (44%) and fatigue (39%), all on visual analogue scales. …”
Get full text

CLINICAL ASSESSMENT OF THE EFFECTIVENESS APPLICATION "BIOCERULIN" IN THE COMPLEX TREATMENT OF THE PATIENTS WITH ONTOGENIC FLAGMONS OF THE MAXILLOFACIAL AREA by D.V. Steblovskyi, V.V. Bondarenko, O.S. Ivanytska, V.M. Skrypnyk, I.O. Ivanytskyi

“…Pain with varying degrees of intensity was present in all patients. Improvement of the general condition of patients of this group was noted not earlier than 3-5 days after surgery. …”
Get full text

Treatment Options for Psychotic Depression in Adolescents: A Comprehensive Review by Perez-Rodriguez V, Aymerich C, Catalan A, Jauhar S, Salazar de Pablo G

“…Finally, we reviewed clinical guidelines to complement the evidence found and provided recommendations for clinical practice. Based on the findings, we recommend a stepped approach to the treatment of psychotic depression in adolescents. …”
Get full text

Transforming healthcare by prioritizing qualitative and quantitative clinical trial evidence: evaluating the Aging, Community and Health Research Unit’s Community Partnership Progr... by Kathryn Fisher, Soo Chan Carusone, Rebecca Ganann, Maureen Markle-Reid, Melissa Northwood, Diana Sherifali

“…However, data are not always congruent, nor is it suboptimal when incongruence occurs, as we illustrate in this case study. We present the divergent findings from a large community-based implementation-effectiveness hybrid type II trial, and how the struggle to reconcile incongruent results yielded rich insights informing the next steps for translational research on the intervention being tested. …”
Get full text

Cultural Malpractices and Associated Factors Among Mothers Attending Postnatal Care Within Six Weeks After Delivery at Gelemso General Hospital, Eastern Ethiopia by Jemaludin Sadik, Dureti Abdurahman, Adera Debella, Elias Yadeta, Rudwan Yasin Abrahim, Nano Belema, Bilisuma Girma, Magarsa Lami, Tegenu Balcha

“…Moreover, there is no study conducted on cultural practice during the postnatal period in this study area. …”
Get full text

Analytical Investigation of Dynamic Response in Cracked Structure Subjected to Moving Load by Shuirong Gui, Hongwei Zeng, Zhisheng Gui, Mingjun Tan, Zhongzhao Guo, Kai Zhong, Yongming Xiong, Wangwang Fang

“…However, the existing methodologies encounter two critical limitations: computational inefficiency and a trade-off between model fidelity and practicality. Thus, this study presents an innovative analytical framework to investigate the dynamic response of cracked simply supported beams subjected to moving loads. …”
Get full text

Integrated solution for patients of a very high cardiovascular risk. Final results by E. I. Usova, M. V. Ionov, A. S. Alieva, N. G. Avdonina, A. N. Yakovlev, N. E. Zvartau

“…For the present analysis the data from 84 (out of 100) patients (median age, 56 (50;61) years, 70 males) was used. …”
Get full text

Awareness among Women about Epidural Analgesia in Riyadh, Saudi Arabia by Sarah W. Alnosaier, Asrar A. Alahmadi, Sarah W. Alnafe, Bandar S. Alshehry

“…The aim of the research is to contribute valuable insights to maternal care practices and enhance informed decision-making among expectant mothers. …”
Get full text

Unveiling the Diagnostic Landscape: Assessing the Rate of Positive Findings in Radiological Imaging by the Emergency Department - A Retrospective Study (December 2022 – February 20... by Fatema Ali Abdulaal, Amr Gebril, Alaa Saleh, Ali Nawaz, Ahmed Kaabneh, Arun Arya

“…Only positive findings directly related to the symptoms presented by patients in the ED were considered, while incidental or non-relevant findings were excluded from the analysis. …”
Get full text

Understanding the nature and dynamics of self-affirmation in non-depressed and subclinically depressed Indian adults: a thematic analysis by Gyanesh Kumar Tiwari, Priyanka Parihar, Ajit Kumar Singh, Amit Kumar Macorya, Anurag Shukla, Archana Singh, Archna Choudhary, Ashutosh Pandey

“…Therapeutic interventions for subclinical depression should focus on improving self-affirmation practices, increasing awareness of self-resources, and attenuating negative cognitive tendencies. …”
Get full text

Enhanced Thermal Resilience of Olive Oils: Fatty Acid Dynamics with Polyphenols Supplementation by Taha Mehany, José M. González-Sáiz, Consuelo Pizarro

“…HTyr-enriched oils present promising potential in both culinary and industrial contexts.…”
Get full text