Optical Coherence Tomography Imaging of the Lamina Cribrosa: Structural Biomarkers in Nonglaucomatous Diseases by Alice Paulo, Pedro G. Vaz, Danilo Andrade De Jesus, Luisa Sánchez Brea, Jan Van Eijgen, João Cardoso, Theo van Walsum, Stefan Klein, Ingeborg Stalmans, João Barbosa Breda

“…All imaging features are presented and discussed in terms of their importance and applicability in clinical practice. …”
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Hybrid Solar PV–Agro-Waste-Driven Combined Heat and Power Energy System as Feasible Energy Source for Schools in Sub-Saharan Africa by Ogheneruona Endurance Diemuodeke, David Vera, Mohammed Moore Ojapah, Chinedum Oscar Nwachukwu, Harold U. Nwosu, Daniel O. Aikhuele, Joseph C. Ofodu, Banasco Seidu Nuhu

“…Poor access to electricity in rural communities has been linked to a poor educational system, as electricity is essential for supporting laboratories, technical practice, and long study hours for students. Therefore, this work presents the techno-economic analysis of a hybrid solar PV–agro-wastes (syngas) energy system for electricity, heat, and cooling generation to improve energy access in rural schools. …”
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Gut microbiome composition and diversity of wild-caught and hatchery-bred milkfish (Chanos chanos) fry by Gardel Xyza L. Silvederio, Therese F. Javellana, Ande Bryle N. Genciana, Maria Alexandra G. Fontanilla, Rex Ferdinand M. Traifalgar, Fredson H. Huervana, Carmelo S. del Castillo

“…Despite numerous studies on gut microbiota of wild and cultured fish species, the diversity and functional roles of the milkfish fry gut microbiome remain poorly understood. This study presents the first gut microbiome profiles of wild and hatchery-bred milkfish fry using 16S rRNA amplicon analysis. …”
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Core outcome set and measures of chest health in children and young people with cerebral palsy in the community setting: the CHESTI study protocol by Jos Latour, Noula Gibson, Harriet Shannon, Christopher Morris, Paul McNamara, Diane Sellers, Rachel Rapson, Madeline Pilbury, Samantha Grace, Laura Lowndes, Julia Melluish, Rachel Knight Lozano, Kayleigh Bell, Hugh Malyon, Morag Andrews, Sarah Crombie, Sian Goddard, Sarah McGoldrick Kolawole, Nicola Scivier, Caroline Weighton, Luana Winston

“…Study findings will be published open access in a peer-reviewed journal and presented at relevant national and international conferences.Study registration COMET registration: 2590 (https://www.comet-initiative.org/Studies/Details/2590)PROSPERO registration number CRD42024562735.…”
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Fluorescent Rhein-Loaded Liposomes for In Vivo Biodistribution Study by Silviu Iulian Filipiuc, Natalia Simionescu, Gabriela Dumitrița Stanciu, Adina Coroaba, Narcisa Laura Marangoci, Leontina Elena Filipiuc, Mariana Pinteala, Cristina Mariana Uritu, Bogdan Ionel Tamba

“…<b>Conclusions:</b> Lip-Rh is a promising candidate for oncological treatments, presenting three key advantages: increased cytotoxicity towards tumour cells, protection of normal tissues, and the practicality of oral delivery. …”
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RNA editing-based biomarker blood test for the diagnosis of bipolar disorder: protocol of the EDIT-B study by Andrea Miranda-Mendizabal, Diana Vetter, Juan Zambrano, Jeff Zarp, Victor Chavarría, Anna Giménez-Palomo, Meritxell Gonzalez-Campos, Marc Valenti, Lara Walczer Baldinazzo, Sara Siddi, Maurizio Ferrari, Dinah Weissmann, Chantal Henry, Josep Maria Haro, Lars Vedel Kessing, Eduard Vieta

“…Ethics and dissemination The principles of the Declaration of Helsinki 2013, precision psychiatry research and good clinical practice will be followed. The Research Ethics Committees of the participating centres approved the study. …”
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Protective effect of resveratrol on retinal damage in glaucoma: a systematic review and meta-analysis of preclinical studies by Feng Zhang, Feng Zhang, Tao Li, Junli Wan, Junli Wan, Lu Wang, Lu Wang, Wenmei Guo, Wenmei Guo, Yue Hu, Yue Hu, Hao Wang, Hao Wang, Wei Bian, Wei Bian

“…IntroductionResveratrol, a polyphenolic compound commonly found in natural plants and fruits, exhibits potential in preventing optic nerve damage in glaucoma, as indicated by several animal studies. However, there is presently a dearth of relevant evidence available for comprehensive summarization.MethodsIn this study, we conducted an extensive search across 7 electronic databases, encompassing all pertinent animal studies for a systematic review and meta-analysis. …”
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Laparoscopic bowel resection combined with infliximab treatment (LaRIC) versus infliximab for terminal ileitis in Crohn’s disease: a randomised, controlled, open-label trial by Yang Yang, Yuan Shi, Yang Luo, Xiuxiu Hao, Tienan Feng, Ran Jing, Sailiang Liu, Yuqi Qiao, Ming Zhong, Minhao Yu

“…Results will be disseminated through peer-reviewed journals and scientific conference presentations.Trial registration number ChiCTR2000029323.…”
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Sustainable assessment of ultrasound-assisted extraction of anthocyanins with bio-based solvents for upgrading grape pomace Cabernet Sauvignon derived from a winemaking process by Andrés Córdova, Sebastián Catalán, Vinka Carrasco, Fabiane O. Farias, Julia Trentin, Jessica López, Fernando Salazar, Cassamo U. Mussagy

“…These results show that integration of UAE and bio-based solvents presented a sustainable and efficient method for valorizing wine making by-products, with significant improvements with respect to the conventional extraction, thus promoting eco-friendly practices for the food industry, and supporting the circular economy.…”
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Impact of Vascular Variations of Superior Mesenteric Artery During Complete Mesocolic Excision for Right Colon Cancer by Gennaro Mazzarella, Diego Coletta, Edoardo Maria Muttillo, Biagio Picardi, Stefano Rossi, Alessandro Scorsi, Simona Meneghini, Bruno Cirillo, Gioia Brachini, Marco Assenza, Andrea Mingoli, Irnerio Angelo Muttillo

“…Complete mesocolic excision (CME) presents technical challenges, primarily due to the considerable variability in the arterial configuration of the right colon. …”
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A national survey on the integration of traditional Chinese medicine and artificial intelligence: attitudes and perceptions from the individuals with health needs by Xinyin Hu, Yinger Gu, Hye Won Lee, Xiaoteng Chen, Ying Li, Xinyue Li, Qiaoping Zhao, Wei Wang, Haifeng Huang, Lisi Wang, Nv Xia, Wenjie Wu, Lingling Lou, Pingchun Yang, Ke Ren, Jinglu Guo, Cheng Wang, Longlong Fan, Zheng Yao, Guomei You, Jue Zhou, Fangfang Wang, Fan Qu

“…Artificial intelligence (AI) opens a new pathway for TCM modernization, while also addressing critical healthcare challenges. The present national survey was conducted to assess the attitudes and perceptions of individuals with health needs regarding the integration of TCM with AI. …”
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Using a “Kickoff” to build implementation partner teams and action plans for active implementation of a quality improvement project by Sean A. Baird, Sean A. Baird, Teresa M. Damush, Teresa M. Damush, Teresa M. Damush, Teresa M. Damush, Nicholas A. Rattray, Nicholas A. Rattray, Nicholas A. Rattray, Nicholas A. Rattray, Lauren S. Penney, Lauren S. Penney, Lauren S. Penney, Edward J. Miech, Edward J. Miech, Edward J. Miech, Edward J. Miech, Barbara J. Homoya, Jared Ferguson, Laura J. Myers, Laura J. Myers, Laura J. Myers, Laura J. Myers, Dawn M. Bravata, Dawn M. Bravata, Dawn M. Bravata, Dawn M. Bravata, Dawn M. Bravata

“…In-person and hybrid set-up of the kickoff, interactive elements, and team formation activities emphasized the quality problem, and motivated site implementation providers to plan for stroke/TIA care improvement.ConclusionsImplementation team kickoffs during pre-implementation are a useful approach to inform and engage local clinical teams and to form plans for practice changes to improve clinical care. Clinical Trial Registrationclinicaltrials.gov, identifier NCT02769338.…”
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No evidence of leukaemia (NEL) as a response criteria in paediatric AML: a multicentre analysisResearch in context by Evangelia Antoniou, Annika Puschnig, Naghmeh Niktoreh, Lina Marie Hoffmeister, Markus Schneider, Carolin Augsburg, Christel Katerkamp, Denise Kondryn, Tabea Ziedrich, Jan-Henning Klusmann, Michael Dworzak, Ursula Creutzig, Nora Mühlegger, Lux Melanie, Katharina Waack, Nils von Neuhoff, Dirk Reinhardt, Stephanie Sendker

“…Interpretation: By simplifying the response criteria for morphological assessment of blast persistence (NEL/EL), we provide an improved and more precise definition of response for paediatric AML, which presents a new milestone with a high prognostic impact in daily clinical practice and in interpreting clinical trials. …”
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Dynamics of Pharmaceuticals in the Soil–Plant System: A Case Study on Mycorrhizal Artichoke by Francesco De Mastro, Gennaro Brunetti, Claudio Cocozza, Sapia Murgolo, Giuseppe Mascolo, Carlo Salerno, Claudia Ruta, Giuseppe De Mastro

“…Contaminants of emerging concern, such as pharmaceuticals (PhACs), are continuously introduced into agro-ecosystems through irrigation with treated wastewater (TWW). While this practice is increasingly common in drought regions, only limited information is available on the fate of PhACs within the soil–plant system. …”
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Implementation of a digital health tool for seizure video transfer in a pediatric epilepsy center: A prospective pilot study by Rahel M. Burger, Gadi Miron, Pascal Fenske, Cornelia Potratz, Angela M. Kaindl, Christian Meisel

“…Home videos are increasingly presented in clinical practice, and secure digital tools for clinical video sharing are urgently needed. …”
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Assessment of the Chemical Hazards in Herbs Consumed in Europe: Toxins, Heavy Metals, and Pesticide Residues by Maria Carpena, Paula Barciela, Ana Perez-Vazquez, Kinga Noras, Joanna Trafiałek, Miguel A. Prieto, Monika Trząskowska

“…In conclusion, this work contributed to identifying gaps and challenges in regulatory practices and to the dialog on the safety and quality of herbs and spices, offering a holistic perspective on toxins, heavy metals, and pesticide residues and fostering collaboration between all stakeholders to advance in public health protection in Europe.…”
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Person-Centered Care in the Home Setting for Parkinson’s Disease: Operation House Call Quality of Care Pilot Study by Nawaz Hack, Umer Akbar, Erin H. Monari, Amanda Eilers, Amanda Thompson-Avila, Nelson H. Hwynn, Ashok Sriram, Ihtsham Haq, Angela Hardwick, Irene A. Malaty, Michael S. Okun

“…All Operation House Call cases are presented during video rounds for the interdisciplinary PD team to make recommendations for care (neurology, neurosurgery, neuropsychology, psychiatry, physical therapy, occupational therapy, speech therapy, and social work). …”
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Explainable machine learning for predicting lung metastasis of colorectal cancer by Zhentian Guo, Zongming Zhang, Limin Liu, Yue Zhao, Zhuo Liu, Chong Zhang, Hui Qi, Jinqiu Feng, Peijie Yao

“…We conducted a validation of the model utilizing data from a Chinese hospital to assess its practicality. Based on this, we have constructed an open web calculator. 39,674 patient data were included in our study, among whom 1369 (3.5%) presented with distant lung metastasis. …”
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Neurologic Physiology after Removal of Therapy (NeuPaRT) study: study protocol of a multicentre, prospective, observational, pilot feasibility study of neurophysiology after withdr... by Charles Weijer, Loretta Norton, Teneille Gofton, Marat Slessarev, Michaël Chasse, John Gordon Boyd, Frédérick D'Aragon, Shane English, Maureen Meade, Sam Shemie, Sonny Dhanani, Andreas H Kramer, Jennifer Chandler, Eileen Campbell, Jeffrey Singh, Yun-Hee Choi, Maxwell J Smith, Erika Chamberlain, Nathan B Scales, Nicholas Murphy, Derek Debicki, Tadeu A Fantaneanu, Julie Kromm, Tracey C Bentall

“…Introduction In donation after circulatory determination of death, death is declared 5 min after circulatory arrest. This practice assumes, but does not explicitly confirm, permanent loss of brain activity. …”
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Syndrome of antibody-dependent enhancement of infection by A. A. Grishaeva, Zh. B. Ponezheva, M. I. Cherenova, O. V. Fedorova, Yu. A. Dobrokhotova, G. N. Khokhlov

“…This phenomenon has been widely studied in dengue fever, however, at present its contribution to the pathogenesis of other viral infections remains poorly understood.Results. …”
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