Multi-region brain transcriptomic analysis of amyotrophic lateral sclerosis reveals widespread RNA alterations and substantial cerebellum involvement by Natalie Grima, Andrew N. Smith, Claire E. Shepherd, Lyndal Henden, Thiri Zaw, Luke Carroll, Dominic B. Rowe, Matthew C. Kiernan, Ian P. Blair, Kelly L. Williams

“…For each individual, five brain regions underwent mRNA sequencing: motor cortex (pTDP-43 inclusions always present), prefrontal cortex and hippocampus (pTDP-43 inclusions sometimes present), and occipital cortex and cerebellum (pTDP-43 inclusions rarely present). …”
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Imaging and pathological characteristics of hepatosplenic EBV-positive inflammatory follicular dendritic cell sarcoma by Yang-Yang Chen, Peng-Ming Wang, Li-Zhu Deng, Pei-Heng Li, Chen-Guang Li, Yu-Hua He, Feng Chen, Jun-Yan Yue

“…Clinical, pathological, and imaging data were evaluated.ResultsHepatosplenic EBV-positive IFDCS primarily occurred in middle-aged adults, with a greater prevalence in females. All cases presented as solitary, well-defined masses, either round or oval in shape. …”
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Clinical phenotype and trio whole exome sequencing data from a patient with glycogen storage disease IV in Indonesia(NCBI) by Ivan William Harsono, Yulia Ariani, Beben Benyamin, Fadilah Fadilah, Dwi Ari Pujianto, Cut Nurul Hafifah, Titis Prawitasari

“…GSD IV occurs once in approximately 1 in every 760,000 to 960,000 live births and is inherited in an autosomal recessive pattern. Early diagnosis of GSD IV is challenging due to non-specific symptoms, such as liver and spleen enlargement, which can overlap with other hematologic and hepatobiliary disorders. …”
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Daytime F Region Echoes at Equatorial Ionization Anomaly Crest During Geomagnetic Quiet Period: Observations From Multi‐Instruments by Yi Liu, Zhongxin Deng, Tong Xu, Jian Kong, Chen Zhou, Yibin Yao, Qiong Tang, Zhengyu Zhao

“…The observed results show that the spatial distributions of daytime F region echo pattern were about 150 km, 200 km, and 180 km in the zonal, meridional, and height extents, respectively. …”
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Simulation of stochastic transport and deposition of seed runaway electrons during disruption mitigation by Yuxiang Sun, Bo Li, Feng Wang, Di Hu, Yue Yuan, Long Cheng, Yuhao Li, the JOREK Team

“…Finally, using a realistic 2D wall, we present the deposition pattern of REs on the first wall to estimate its asymmetry.…”
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Flea-borne Rickettsia species in fleas, Caldas department, Colombia by Carol B Colonia, Alejandro Ramírez-Hernández, Juliana Gil-Mora, Juan C Agudelo, Gabriel Jaime Castaño Villa, Camilo Pino, Paola Betancourt-Ruiz, Jorge E Pérez Cárdenas, Lucas S Blanton, Marylin Hidalgo

“…Conclusion: The present study confirms the presence and high prevalence of R. asembonensis and R. felis in fleas from domestic and wild animals in different municipalities from Caldas Department. …”
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Effect of Body Position on Electrical Activity of Respiratory Muscles During Mouth and Nasal Maximal Respiratory Pressure in Healthy Adults: A Pilot Study by Lailane Saturnino da Silva, Rayane Grayce da Silva Vieira, Thiago Bezerra Wanderley e Lima, Vanessa Regiane Resqueti, Jordi Vilaro, Jessica Danielle Medeiros da Fonseca, Giane Amorim Ribeiro-Samora, Guilherme Augusto de Freitas Fregonezi

“…<b>Conclusions</b>: The results suggest there are significant differences in inspiratory pressures between positions, with the difference in activity muscle pattern. In conclusion, body position affected maximal respiratory pressures and influences EMG activation of specific respiratory muscles during MIP.…”
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Long term effect of infection control practices and associated factors during a major Clostridium difficile outbreak in Costa Rica by Roy A Wong-McClure, Elenita Ramírez-Salas, Nury Mora-Brenes, Lorena Aguero-Sandí, Maritza Morera-Sigler, Xiomara Badilla-Vargas, Marcela Hernández-de Merzerville, Michele O’Shea, Elizabeth Bryce

“…Introduction: The C. difficile BI/NAP 1 hyper virulent strain has been responsible for the nosocomial outbreaks in several countries. The present study describes the infection control strategies utilized to achieve outbreak control as well as the factors associated with a C. difficile BI/NAP 1 hyper virulent strain outbreak in Costa Rica. …”
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Effects of various packaging materials and temperature conditions on the storage stability of Zea mays L. (baby corn) powder by Ubaida Akbar, Md Sabir Ahmed Mondol, Jyoti Singh, Prasad Rasane, Vikas Nanda, Gholamreza Abdi, Sawinder Kaur

“…The sorption isotherms displayed a Type II pattern with distinct bending points, revealing temperature-dependent moisture retention. …”
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Reefing Viability Index for Rigs-to-Reefs (R2R) in Malaysia by Mohd Hairil Mohd, Mohd Asamudin A. Rahman, Muhammad Nadzrin Nazri, Chun Hong Tan, Yuzwan Mohamad, Chuin Siew Lim, Baharim Mustapa, Hasrizal Shaari, Yii Siang Hii, Do Kyun Kim

“…The platform was reused to serve the underwater ecosystem as an artificial reef for a new marine ecosystem which helps to tackle food security issue. This paper presents the findings of the formulation of the reefing viability index to recognize an offshore region that can be used for R2R projects within the South China Sea. …”
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Evaluating the effectiveness of the Shan-Shui Initiatives in China by Yutong Jiang, Xinghao Shan, Qingyu Liu, Yu Feng, Yuyang Lai, Kaiji Xu, Jinman Wang, Zhongke Bai, Xiaoming Feng

“…The spillover effects were widely present and the prevalence of positive spillover effects was notably greater than that of negative ones. …”
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A Noninvasive System for the Automatic Detection of Gliomas Based on Hybrid Features and PSO-KSVM by Guoli Song, Zheng Huang, Yiwen Zhao, Xingang Zhao, Yunhui Liu, Min Bao, Jianda Han, Peng Li

“…First, image standardization, including size normalization and background removal, is applied to produce standard images; then, the modified dynamic histogram equalization is implemented to enhance the low-contrast standard brain images, and skull removal based on outlier detection is presented. Furthermore, hybrid features, including gray-level co-occurrence matrix, pyramid histogram of the oriented gradient, modified completed local binary pattern, and intensity-based features are extracted together from the enhanced images, and their dimensions are reduced by principal component analysis. …”
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Surface creep differences and affecting factor along the Xianshuihe fault zone in response to the Wenchuan and Lushan earthquakes by Guanzhong Liu, Aichun Liu, Qin Su, Lianglong Fan, Ao Song, Aipeng Guo, Yanxing Li

“…Consequently, it is pertinent to consider the potential response of fault creep in the XSHFZ when the LMSFZ encounters different major earthquake disturbances. This paper presents a comparative and analytical study of the fault creep characteristics of the XSHFZ, employing cross-fault short-baseline survey data collected prior to and following the Wenchuan M8.0 and Lushan M7.0 earthquakes. …”
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Management of adult patients with alcoholic liver disease: clinical guidelines of the Russian Scientific Liver Society by V. T. Ivashkin, M. V. Mayevskaya, Ch. S. Pavlov, Yu. P. Sivolap, V. D. Lunkov, M. S. Zharkova, R. V. Maslennikov

“…The aim of publication. To present clinical guidelines of the Russian Scientific Liver Society on diagnosis and treatment of alcoholic liver disease to general practitioners. …”
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An approach to the meso-scale epidemiological behavior of Plasmodiophora brassicae from cruciferous crops under tropical conditions; Supplementary material by Andres F. Quintero-Mercado, Juan Camilo Garcia-Peña, Andrea Botero-Ramirez, Celsa Garcia, Joaquín Guillermo Ramírez-Gil

“…The meso- and macroscale spatial risk model was developed under point pattern approaches (Kernel density model and ecological niche model (ENM). …”
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Retinoic and ascorbic acids induce osteoblast differentiation from human dental pulp mesenchymal stem cells by Lina M. Escobar, José Daniel Escobar, Zita Bendahan, Jaime E. Castellanos

“…Morphologically, the cells treated with RA and RA ​+ ​AA were larger and more elongated than the control cells. A mesh pattern was observed in cells treated with AA. Numerous calcified nodules were present in cells treated with RA, AA, and RA ​+ ​AA. …”
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Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women by Emily Delgouffe, Samuel Madureira Silva, Frédéric Chalmel, Wilfried Cools, Camille Raets, Kelly Tilleman, Guy T'Sjoen, Yoni Baert, Ellen Goossens

“…Although most peritubular myoid cells expressed alpha-smooth muscle actin 2, the expression pattern was disturbed. Besides this, fibrosis was particularly evident in the tubular wall and the lumen was collapsing in most participants. …”
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Speciation studies of potentially toxic elements within the vicinity of major dumpsites in Ile-Ife, Osun State, Nigeria by Oluwakemi O. Tovide, John A.O. Oyekunle, Odunayo T. Ore, Bukola A. Oyebode, Elizabeth O. Moseri, Abolanle S. Adekunle, Oluwasegun Oluwarotimi, Aderemi O. Ogunfowokan, Adebayo O. Eludoyin

“…The study found that the dumpsite soils presented little environmental concern, even though metal amounts varied throughout sampling points. …”
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Molecular genetic profiling of a rare case of primary pulmonary adenoid cystic carcinoma: Insights from whole exome sequencing and literature review by Jianhao Xu, Fang Cao, Liqian Yao, Jingfeng Gu, Lanfen Pan, Jiarui Min, Zijie Xu, Jihao Su, Zhiyong Deng, Song Xu

“…Results: A 56-year-old male presented with a left lower lobe mass identified on chest CT during a routine health check. …”
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Gastric Medullary Carcinoma with Sporadic Mismatch Repair Deficiency and a TP53 R273C Mutation: An Unusual Case with Wild-Type BRAF by Brett M. Lowenthal, Theresa W. Chan, John A. Thorson, Kaitlyn J. Kelly, Thomas J. Savides, Mark A. Valasek

“…We report a 67-year-old male who presented with a solitary gastric mass. Total gastrectomy revealed a well-demarcated, poorly differentiated carcinoma with an organoid growth pattern, pushing borders, and abundant peritumoral lymphocytic response. …”
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