MassCube improves accuracy for metabolomics data processing from raw files to phenotype classifiers by Huaxu Yu, Jun Ding, Tong Shen, Min Liu, Yuanyue Li, Oliver Fiehn

“…Final data tables undergo quality controls and can be used for metabolome-informed phenotype prediction. Peak detection in MassCube achieves 100% signal coverage with comprehensive reporting of chromatographic metadata for quality assurance. …”
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Investigating pea (Pisum sativum L.) flowering with high throughput field phenotyping and object detection by Corina Oppliger, Radek Zenkl, Achim Walter, Beat Keller

“…Today, high-throughput field phenotyping (HTFP) methods provide opportunities for objective and efficient data collection. …”
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Phenotypic tolerance for rDNA copy number variation within the natural range of C. elegans. by Ashley N Hall, Elizabeth A Morton, Rebecca Walters, Josh T Cuperus, Christine Queitsch

“…We find that rDNA copy number is stable in the RILs, rejecting prior hypotheses that predicted copy number instability and copy number reversion. …”
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Elucidating the molecular basis of salt tolerance in potatoes through miRNA expression and phenotypic analysis by Caicai Lin, Shuangshuang Zheng, Kui Liu, Ru Yu, Peiyan Guan, Baigeng Hu, Lingling Jiang, Mengyu Su, Guodong Hu, Qingshuai Chen, Xia Zhang

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Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians. by Danielle Ireland, Christina Rabeler, Sagar Rao, Rudy J Richardson, Eva-Maria S Collins

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Advanced Plant Phenotyping Technologies for Enhanced Detection and Mode of Action Analysis of Herbicide Damage Management by Zhongzhong Niu, Xuan Li, Tianzhang Zhao, Zhiyuan Chen, Jian Jin

“…The integration of machine learning algorithms with imaging data further enhances the ability to detect subtle phenotypic changes, predict herbicide resistance, and facilitate timely interventions. …”
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DEPDC1 facilitated malignant phenotypes and disease progression of liposarcoma by modulating KIF20A by Mingwei Yu, Huishan Zhao, Yujie Sun

“…Furthermore, potential interacting proteins of DEPDC1 were predicted by STRING, and the DEPDC1-KIF20A interaction was confirmed by co-immunoprecipitation in liposarcoma cells. …”
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Improved YOLOv8 Model for Phenotype Detection of Horticultural Seedling Growth Based on Digital Cousin by Yuhao Song, Lin Yang, Shuo Li, Xin Yang, Chi Ma, Yuan Huang, Aamir Hussain

“…Crop phenotype detection is a precise way to understand and predict the growth of horticultural seedlings in the smart agriculture era to increase the cost-effectiveness and energy efficiency of agricultural production. …”
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Analysis of the Clinicopathological Characteristics, Genetic Phenotypes, and Prognostics of Primary Pulmonary and Bronchial Adenoid Cystic Carcinoma by Zhengyang Hu, Xing Jin, Jian Wang, Qihai Sui, Yanjun Yi, Dejun Zeng, Zhencong Chen, Qun Wang, Jiacheng Yin, Lin Wang, Zongwu Lin

“…Conclusion Our study analyzed the main factors that influence the prognosis of PACC patients undergoing surgery and discovered the unique genetic phenotype of PACC.…”
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Genotype‐function‐phenotype correlations for SCN1A variants identified by clinical genetic testing by Andrew T. Knox, Christopher H. Thompson, Dillon Scott, Tatiana V. Abramova, Bethany Stieve, Abigail Freeman, Alfred L. George Jr.

“…We combined automated patch clamp recording with neurophysiological simulations to discern genotype‐function‐phenotype correlations in a real‐world cohort of children with SCN1A‐associated epilepsy. …”
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Lung function and peak oxygen uptake in chronic obstructive pulmonary disease phenotypes with and without emphysema. by Øystein Rasch-Halvorsen, Erlend Hassel, Ben M Brumpton, Haldor Jenssen, Martijn A Spruit, Arnulf Langhammer, Sigurd Steinshamn

“…Corresponding assessments using standardized percent predicted FEV1 (ppFEV1) were performed for comparison. …”
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Epigenetic determinants of an immune-evasive phenotype in HER2-low triple-negative breast cancer by Andrés F. Bedoya-López, Sookyung Ahn, Miquel Ensenyat-Mendez, Javier I. J. Orozco, Sandra Iñiguez-Muñoz, Pere Llinàs-Arias, Samantha M. Thomas, Jennifer L. Baker, Peggy S. Sullivan, Jitin Makker, Julie B. Steele, Sunil M. Kurian, Diego M. Marzese, Maggie L. DiNome

“…While HER2-low expression predicts response to novel antibody-drug conjugates, its biological influence on TNBC biology is unknown. …”
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Single-cell microbiota phenotyping reveals distinct disease and therapy-associated signatures in Crohn’s disease by Lisa Budzinski, Gi-Ung Kang, René Riedel, Toni Sempert, Leonie Lietz, René Maier, Janine Büttner, Bettina Bochow, Marcell T. Tordai, Aayushi Shah, Amro Abbas, Tanisha Momtaz, Jannike L. Krause, Robin Kempkens, Katrin Lehman, Gitta A. Heinz, Anne E. Benken, Stefanie Bartsch, Kathleen Necke, Ute Hoffmann, Mir-Farzin Mashreghi, Robert Biesen, Tilmann Kallinich, Tobias Alexander, Bosse Jessen, Carl Weidinger, Britta Siegmund, Andreas Radbruch, Anja Schirbel, Benjamin Moser, Hyun-Dong Chang

“…In addition, we identified phenotypic signatures in the CD microbiota which not only reflected remission after 6 weeks of anti-TNF treatment, but were also able to predict remission before the start of an adalimumab treatment course in a pilot study. …”
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Clinical Phenotypes of Patients with Neovascular Age-Related Macular Degeneration and Poor Response to Aflibercept Treatment by V. G. Likhvantseva, A. S. Gevorgyan, S. G. Kapkova, E. Yu. Nekrasova

“…The presented descriptions of clinical phenotypes of eyes with nVMD depending on their response to treatment with Aflibercept may be useful in predicting the response to treatment.…”
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Incidence of cardiovascular risk factors and exercise phenotyping in cardiomyopathies: One size does not fit all by Simon Wernhart, Florian Karcher, Mark J Haykowsky, Martin Halle

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VEGF-R1/Flt-1 Receptor as a Characteristic of the Angiogenic Phenotype of Uveal Melanoma by V. G. Likhvantseva, O. A. Anurova, S. E. Astakhova, M. V. Vereshchagina, V. E. Ovanesyan, E. V. Stepanova

“…One of the characteristics of the angiogenic phenotype is VEGF-R1/Flt-1. The purpose: to study the expression of the VEGF-R1/Flt-1 receptor as a characteristic of the angiogenic phenotype of UM in correlation with its clinical and morphological indicators and the outcome of the disease. …”
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Comprehensive Analysis of Phenotypic Traits in Chinese Cabbage Using 3D Point Cloud Technology by Chongchong Yang, Lei Sun, Jun Zhang, Xiaofei Fan, Dongfang Zhang, Tianyi Ren, Minggeng Liu, Zhiming Zhang, Wei Ma

“…Studies on the phenotypic traits and their associations in Chinese cabbage lack precise and objective digital evaluation metrics. …”
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Prognostic and predictive molecular biomarkers of colorectal cancer by A. D. Shakhmatova, E. D. Mirlina, G. M. Butrovich, O. A. Vostriukhina, V. N. Verbenko

“…лукиан самосаткийThe search and application of genetic prognostic and predictive biomarkers in colorectal cancer (CRC) are aimed at identifying the characteristics of colorectal tumors for choosing a therapy strategy. …”
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Mendelian randomization analyses support causal relationship between brain imaging-derived phenotypes and risk of low back pain by Xiao-Yan Xie, Jian-Wei Lin, Jia-Yu Fang, Zhuo-Chen Chen, Peng-Cheng Li, Xiao-Yan Huang, Ming-Yan Guo, Li-Ling Lin, Ming-Hui Cao

“…Our findings provide potential strategies for predicting LBP risk at the brain-imaging level.…”
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Enhancing the sustainability of rabbit production from the perspective of animal genetics by Juan Pablo Sánchez

“…In the near future, we could predict that breeding programmes for enhanced sustainability will still mainly rely on pedigree records and phenotypic information for prolificacy and feed efficiency; but enriching the list of available phenotypes with additional traits, most likely obtained under automatic recording systems, to explicitly account for the social and environmental sustainability plans. …”
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