CO15 | Longitudinal coagulation profiling of individuals undergoing gender-affirming hormone therapy: the hyper-gender study

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CO26 | Relationship between SMAD3 variants and non-aortic cardiovascular features

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CO16 | The predictive value of high-sensitivity C-reactive protein for assessing thrombosis risk in non-small cell lung cancer

“…Thromboinflammation is correlated not only with VTE but also with a more aggressive cancer phenotype. Aims: In a large, prospective, multinational, observational study involving newly diagnosed NSCLC patients, we evaluated a panel of hypercoagulable biomarkers, along with high-sensitivity C-reactive protein (hs-CRP), to determine their predictive significance for the occurrence of VTE within 6 months of initiating chemotherapy. …”
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Single nucleotide variants in transcription factors associate more tightly with phenotype than with gene expression. by Priya Sudarsanam, Barak A Cohen

“…We find that the amount of gene expression variation explained by the sporulation QTN is not predictive of the amount of phenotypic variation explained. …”
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Comparative evaluation of six phenotypic methods for detecting extended-spectrum beta-lactamase-producing Enterobacteriaceae by Rajkumar Manojkumar Singh, Huidrom Lokhendro Singh

“…Introduction: Various conventional phenotypic methods and automated systems have been evaluated for extended-spectrum beta-lactamase (ESBL) detection. …”
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Phenotyping-based spectral signatures uncover barley cultivars’ sensitivity to combined mildew and drought treatment by Chandana Pandey, Søren Gjedde Sommer, Thomas Roitsch, Alexander Schulz

“…The plant’s phenotype changes under biotic and abiotic stress, reflecting its adaptations in gene expression and metabolism. …”
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Three Novel <i>KIT</i> Polymorphisms Found in Horses with White Coat Color Phenotypes by Nikol A. Obradovic, Aiden McFadden, Katie Martin, Micaela Vierra, Kaitlyn McLoone, Erik Martin, Adelaide Thomas, Robin E. Everts, Samantha A. Brooks, Christa Lafayette

“…The severe predicted impact on biological function suggests that these variants may cause increased white spotting, providing a possible explanation for the depigmentation phenotypes observed in affected individuals.…”
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Cytogenetic aberration in mixed-phenotype acute leukemia in children: A single-center retrospective review by Tsung-Yen Chang, Shih-Hsiang Chen, Tang-Her Jaing, Shu-Ho Yang, Yu-Chuan Wen, Chao-Ping Yang, Iou-Jih Hung

“…Background: Mixed-phenotype acute leukemia (MPAL) poses a diagnostic and therapeutic dilemma. …”
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Integration of Digital Phenotyping and Genomics for Dry Eye Disease: Protocol for a Prospective Cohort Study by Ken Nagino, Yasutsugu Akasaki, Nobuo Fuse, Soichi Ogishima, Atsushi Shimizu, Akira Uruno, Yoichi Sutoh, Yayoi Otsuka-Yamasaki, Fuji Nagami, Jun Seita, Tomohiro Nakamura, Satoshi Nagaie, Makiko Taira, Tomoko Kobayashi, Ritsuko Shimizu, Atsushi Hozawa, Shinichi Kuriyama, Atsuko Eguchi, Akie Midorikawa-Inomata, Masahiro Nakamura, Akira Murakami, Shintaro Nakao, Takenori Inomata

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Audiometry as a predictive proxy for balance dysfunction by Cécile Nicolas-Puel, Jérôme Bourien, Régis Nouvian, Jean-Luc Puel, Jean-Charles Ceccato

“…Our findings suggest that audiometric assessments can provide predictive insights into vestibular dysfunction. These audiometric phenotypes represent valuable tools for refining diagnoses and facilitating personalized management of patients with balance disorders.…”
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Classification of Signature-Based Phenotypes of Aging-Related Genes to Identify Prognostic and Immune Characteristics in HCC by Junjie Zhao, Chong Li, Qinggang Li, Shen Shen, Xiaobo Hu, Zihui Dong, Yize Zhang, Jiyuan Xing

“…Hepatocellular carcinoma (HCC), which has become one of the most significant malignancies causing cancer-related mortality, presents genetic and phenotypic heterogeneity that makes predicting prognosis challenging. …”
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Variants in Candidate Genes for Phenotype Heterogeneity in Patients with the 22q11.2 Deletion Syndrome by Natalia Nunes, Beatriz Carvalho Nunes, Malú Zamariolli, Diogo Cordeiro de Queiroz Soares, Leonardo Caires dos Santos, Anelisa Gollo Dantas, Vera Ayres Meloni, Sintia Iole Belangero, Vera Lúcia Gil-Da-Silva-Lopes, Chong Ae Kim, Maria Isabel Melaragno

“…In silico prediction was performed, and the whole-genome sequencing annotation analysis package (WGSA) was used to predict the possible pathogenic effect of single nucleotide variants (SNVs). …”
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Genetic and bioinformatics analysis of an individual with Am phenotype due to variant of A-glycosyltransferase enzyme gene by ZHANG Xu, ZHOU Zhuren, HUANG Xuying, LI Lichun, LI Xiaofeng, LI Jianping

“…Objective To investigate the serological characteristics and molecular mechanism of an individual with Am phenotype. Methods The sample with ABO blood group discrepancy was confirmed by serological techniques. …”
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A SuperLearner-based pipeline for the development of DNA methylation-derived predictors of phenotypic traits. by Dennis Khodasevich, Nina Holland, Lars van der Laan, Andres Cardenas

“…The SL PCA clocks improved fit with observed phenotypes relative to the PCA clocks or CpG clocks across several datasets. …”
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High throughput phenotyping in soybean breeding using RGB image vegetation indices based on drone by Andressa K. S. Alves, Maurício S. Araújo, Saulo F. S. Chaves, Luiz Antônio S. Dias, Lucas P. Corrêdo, Gabriel G. F. A. Pessoa, André R. G. Bezerra

“…We used a linear mixed effects model, with restricted maximum likelihood (REML)/best linear unbiased prediction (BLUP) methods, to estimate variance components and genetic correlations, and to predict genotypic values. …”
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Comparison of genotypes and phenotypes for von Willebrand factor gene variants using Japanese genome database by Takafumi Akimoto, Hiroshi Inaba, Soichi Ogishima, Kazuki Kumada, Ayano Mitsuhashi, Ryui Miyashita, Tomoko Yamaguchi, Masato Bingo, Yushi Chikasawa, Keiko Shinozawa, Takeshi Hagiwara, Kagehiro Amano, Eiichi N. Kodama, Ei Kinai

“…The aim of this study was to determine the predicted disease states associated with various pathogenic von Willebrand factor (VWF) variants and their phenotypes using the largest Japanese whole-genome database. …”
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Uncovering precision phenotype-biomarker associations in traumatic brain injury using topological data analysis. by Jessica L Nielson, Shelly R Cooper, John K Yue, Marco D Sorani, Tomoo Inoue, Esther L Yuh, Pratik Mukherjee, Tanya C Petrossian, Jesse Paquette, Pek Y Lum, Gunnar E Carlsson, Mary J Vassar, Hester F Lingsma, Wayne A Gordon, Alex B Valadka, David O Okonkwo, Geoffrey T Manley, Adam R Ferguson, TRACK-TBI Investigators

“…<h4>Conclusions</h4>TDA identified a unique diagnostic subgroup of patients with unfavorable outcome after mild TBI that were significantly predicted by the presence of specific genetic polymorphisms. …”
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Polyamine Metabolism Promotes the Progression of Thyroid Carcinoma by Regulating the Immune Phenotype of Tumor Associated Macrophages by Haoran Ding, Lingling Xue, Shaoshi Zhu, Ziyu Wang, Huan Gui, Guang Zhang, Ning Tang, Haozhen Ren, Dayu Chen

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Prognostic Significance of Macrophage Phenotypes in Peri-Tumoral Normal Tissue of Early-Stage Breast Cancer by Marcel Hirschmann, Sören Schnellhardt, Matthias Rübner, Sarah Segelhorst, Oliver Ott, Ramona Erber, Christoph Daniel, Maike Büttner-Herold, Paul Gass, Rainer Fietkau, Luitpold Distel

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Characterization of lactylation-based phenotypes and molecular biomarkers in sepsis-associated acute respiratory distress syndrome by Yiheng Wang, An Wei, Zixuan Su, Yunyi Shi, Xinqiu Li, Lixian He

“…KEGG pathway analysis, drug sensitivity prediction, and immune cell infiltration analysis were performed. …”
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