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7401
Targeting Refractory Triple-Negative Breast Cancer with Sacituzumab Govitecan: A New Era in Precision Medicine
Published 2024-12-01“…Advanced triple-negative breast cancer (TNBC) has poorer outcomes due to its aggressive behavior and restricted therapeutic options. While therapies like checkpoint inhibitors and PARP inhibitors offer some benefits, chemotherapy remains ineffective beyond the first line of treatment. …”
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7402
Neuroprotective Potential of <i>Origanum majorana</i> L. Essential Oil Against Scopolamine-Induced Memory Deficits and Oxidative Stress in a Zebrafish Model
Published 2025-01-01“…In parallel, we performed in silico predictions (research conducted using computational models) of the pharmacokinetic properties of the main compounds identified in OmEO, using platforms such as SwissADME, pKCSM, ADMETlab 2.0, and ProTox-II. …”
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7403
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7404
Local elections 2000: analyzing the results of the elections
Published 2000-04-01“…Analyzing the party behavior after the elections allows one to expect that notwithstanding prior situation in Lithuania these processes would become reality for the first time. …”
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7405
In Silico and in vitro evaluation of the anticancer effect of a 1,5-Benzodiazepin-2-One derivative (3b) revealing potent dual inhibition of HER2 and HDAC1
Published 2025-04-01“…To investigate the anticancer effect of 3b, in silico prediction of the possible targets were performed. Then, the predicted targets were investigated through in vitro study. …”
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7406
Dingzhen pills inhibit neuronal ferroptosis and neuroinflammation by inhibiting the cGAS-STING pathway for Parkinson’s disease mice
Published 2025-06-01“…Methods The effect of DZP on the behavior of movement disorders in a mouse model of MPTP-induced was first evaluated. …”
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7407
Enhancing ovarian cancer prognosis with an artificial intelligence-derived model: Multi-omics integration and therapeutic implications
Published 2025-09-01“…Results: The AIDPI model demonstrated superior accuracy in predicting ovarian cancer prognosis compared to existing models. …”
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7408
Assessing Sleep Quality Using Mobile EMAs: Opportunities, Practical Consideration, and Challenges
Published 2022-01-01“…The result of analysis indicates that features using both daily indexes and sleep questionnaires lead to better prediction of sleep quality. Additionally, it also shows the potential to generate indicators identifying complex human behaviors with the help of mobile devices and EMAs. …”
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7409
Social profiles among youth with attention-deficit/hyperactivity disorder (ADHD): Evidence from the ABCD study
Published 2025-10-01“…A growing body of literature supports the utility of the NIMH’s Research Domain Criteria (RDoC) framework, which emphasizes broad neurobiological based dimensions, allowing for the integration of models of both neural circuitry and behavior when examining externalizing behaviors in youth. …”
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7410
Liquid–liquid–solid three-phase flow in horizontal wells: flow pattern modeling and dimensionless analysis
Published 2025-03-01“…To better understand the impact of various parameters and to analyze the interaction and competrion between different forces applied under each flow pattern condition three-phase dimensionless Weber and Reynolds numbers have been defined which enables us to accurately predicted the multiphase flow system behavior regardless of the system scale. …”
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7411
Association of school leaders’ COVID-19 health literacy with the implementation of health promotion in schools in Germany: a cross-sectional study
Published 2025-08-01“…They are not only responsible for school functioning, but school principals’ behavior and attitudes are also associated with health promoting school activities. …”
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7412
DCUN1D5 is a prognostic biomarker and correlated immune infiltrates and glycolysis in lung adenocarcinoma
Published 2025-01-01“…Down-regulation of DCUN1D5 can significantly affect the biological behavior of lung adenocarcinoma cells, which may be related to glycolysis and immune cell infiltration.…”
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7413
Appendix Neuroendocrine Tumor: Retrospective Analysis of 4026 Appendectomy Patients in a Single Center
Published 2020-01-01“…Symptoms are mostly related to tumor size and distant metastases. Clinical behavior and prognosis can best be predicted by tumor size. …”
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7414
Impact of HIF-1α, LOX and ITGA5 Synergistic Interaction in the Tumor Microenvironment on Colorectal Cancer Prognosis
Published 2025-01-01“…<b>Background</b>: As colorectal cancers are histopathologically and molecularly highly heterogeneous tumors, it is necessary to consider the tumor’s microenvironment as well as its cellular characteristics in order to determine the biological behavior of the tumor. This study included 100 patients who underwent resection for colorectal cancer. …”
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7415
The ideals of student youth in relation to the present, possible and anti-ideal
Published 2022-04-01“…The results are useful for analysing and predicting the social behavior of young people.…”
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7416
Vibration Signal Analysis for Intelligent Rotating Machinery Diagnosis and Prognosis: A Comprehensive Systematic Literature Review
Published 2024-10-01“…Meanwhile, transformer-based models are emerging as a promising venue for the prediction of RUL values, along with data transformation. …”
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7417
Theoretical investigation of the two-dimensional V2C2/V2C2F2 as prospective host materials for Li- and Na-ion batteries
Published 2025-05-01“…These features indicate that the predicted 2D V2C2 compound is a promising candidate for use as an anode material in lithium- or sodium-ion batteries. …”
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7418
Secure Cooperative Dual-RIS-Aided V2V Communication: An Evolutionary Transformer–GRU Framework for Secrecy Rate Maximization in Vehicular Networks
Published 2025-07-01“…Our model integrates the sequence modeling strength of GRUs with the global attention mechanism of transformer encoders, enabling the efficient representation of time-series channel behavior and long-range dependencies. To further enhance convergence and secrecy performance, we incorporate an improved gray wolf optimizer (IGWO) to adaptively regulate the model’s hyper-parameters and fine-tune the RIS phase shifts, resulting in a more stable and optimized learning process. …”
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7419
Experimental evaluation of a NACA-0022 airfoil under steady and dynamic pitch oscillations at low Reynolds numbers for wind power applications
Published 2025-06-01“…The dynamic behavior is vital for Vertical Axis Wind Turbines (VAWTs), since the blades continuously experience cyclic stall conditions. …”
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7420
Identifying Optimal Wearable Devices for Monitoring Mobility in Hospitalized Older Adults: Feasibility, Acceptability, and Validity Study
Published 2025-05-01“…The thigh-worn ActiGraph accurately detected sedentary behavior, while the ankle-worn device provided detailed information on step counts and body postures. …”
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