Determining optimal strategies for primary prevention of cardiovascular disease: systematic review of cost-effectiveness analyses in the United Kingdom by Hema Mistry, Jodie Enderby, Rachel Court, Lena Al-Khudairy, Chidozie Nduka, GJ Melendez-Torres, Sian Taylor-Phillips, Aileen Clarke, Olalekan Uthman

“…(Philips Z, Ginnelly L, Sculpher M, Claxton K, Golder S, Riemsma R, et al. Review of guidelines for good practice in decision-analytic modelling in health technology assessment. …”
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Does Valve-Sparing Repair Improve Outcomes in Tetralogy of Fallot? A Systematic Review by Jabez David John, Tirath Patel, Monica Kharat, Jeet HansalKumar Patel, Jubran Al Hooti, Zoya Riyaz Syeda, Rohit Anil Khare, Sonya Bhatia, Amin Ibrahim, Arjun Bellamkonda, Nikhilesh Anand, Bharathi S. Gadad

“…It can be a foundation for clinical practice that allows surgeons to make better, informed decisions about patient care. …”
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African New Towns by Rachel Keeton

“…The analysis of shared spatial challenges is used to revise, expand and refine these guidelines into a set of adaptive planning and design principles specific to African New Towns. …”
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Mind the Gap in Kidney Care: Translating What We Know into What We Do by Valerie A. Luyckx, Katherine R. Tuttle, Dina Abdellatif, Ricardo Correa-Rotter, Winston W.S. Fung, Agnès Haris, Li-Li Hsiao, Makram Khalife, Latha A. Kumaraswami, Fiona Loud, Vasundhara Raghavan, Stefanos Roumeliotis, Marianella Sierra, Ifeoma Ulasi, Bill Wang, Siu-Fai Lui, Vassilios Liakopoulos, Alessandro Balducci, Alessandro Balducci, Vassilios Liakopoulos, Li-Li Hsiao, Ricardo Correa-Rotter, Ifeoma Ulasi, Latha Kumaraswami, Siu Fai Lui, Dina Abdellatif, Ágnes Haris

“…Historically, it takes an average of 17 years to move new treatments from clinical evidence to daily practice. Given the highly effective treatments now available to prevent or delay kidney disease onset and progression, this is far too long. …”
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Emerging evidence to reduce the burden of tuberculosis in children and young people by Julie Huynh, Yara-Natalie Abo, Rina Triasih, Varinder Singh, Gordon Pukai, Pauline Masta, Bazarragchaa Tsogt, Boi Khanh Luu, Felisia Felisia, Naomi Pank, Aung Aung, Alison Morton, Pete Azzopardi, Raspati C. Koesoemadinata, Bachti Alisjahbana, Philip C. Hill, Ben J. Marais, Silvia S. Chiang, Stephen M. Graham

“…These advances have informed global policy and guidelines; however, major gaps in translation from policy to practice remain. …”
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Comparative effectiveness of monotherapy vs. combination therapy for postoperative central nervous system infections in neurosurgical patients: a retrospective cohort study by Muyun Li, Wei Meng, Linna An, Xiaoqi Lin, Shangjie Yang, Qiang Fu, Qiuxia Shi, Dongfeng Li, Jie Wang, Jianhua Wang, Yubo Wang

“…Abstract Background Although clinical guidelines recommend vancomycin-based combination therapy for patients with postoperative intracranial infections in neurosurgery, the trend of global bacterial resistance and the management of antimicrobial agents have made monotherapy a common treatment option for some patients. …”
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Risk predictors of severe adverse maternal outcomes in pre-eclampsia: a systematic review and meta-analysis protocol by Anish Keepanasseril, Farid Foroutan, Rohan D’Souza, Lindsay Hales, Kara Nerenberg, Isabelle Malhamé, Harika Dasari, Meriem Hammache, Bérengère Deveaux-Cattino, Sophia Bourgeois, Sonia M. Grandi, Stella S. Daskalopoulou

“…While numerous studies have explored potential risk markers, there is still no consensus on the most reliable factors and models to use in clinical practice. This systematic review aims to consolidate research on both individual predictors and prognostic models of severe adverse maternal outcomes in PE, providing a comprehensive overview to support better clinical decision-making and patient care.Methods and analysis This review follows the Meta-analyses Of Observational Studies in Epidemiology (MOOSE) guidelines and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Protocol 2015 checklist. …”
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Ward AdmiSsion of Haematuria: an Observational mUlticentre sTudy (WASHOUT) – study protocol by Graeme Maclennan, Kevin Gallagher, John McGrath, Veeru Kasivisvanathan, James Catto, Maria Ribal, Aqua Asif, Alexander Ng, Ben Challacombe, Arjun Nathan, Nikki Kerdegari, Nikita Bhatt, Kevin Byrnes, Simona Ippoliti, Raghav Varma, Bing Jie Chow, Quentin Mak, Ben Lamb, Sinan Khadhouri

“…A systematic review performed by our research group found no large-scale prospective studies have been performed in this area, and little is known about current practice. This study aims to address these gaps by investigating current management practices and their impact on outcomes, with the goal of informing evidence-based guidelines and improving patient care.Methods and analysis The Ward AdmiSsion of Haematuria: an Observational mUlticentre sTudy is an international, multicentre prospective observational study designed to describe the management of patients with unplanned admission to hospital with haematuria under the care of the urology team. …”
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Antiplatelet Resumption After Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis by Sarah Yahya Alharthi, Sarah Abdulaziz Alsheikh, Dawood Salman Almousa, Saud Samer A. Alsedrah, Nouf Mohammed Alshammari, Mariam Mostafa Elsayed, Rahaf Ali Hamed AlShamrani, Mohammed Ahmed Yaslam Bellahwal, Abdulrahman Alnwiji, Raed A. Albar, Ayman M. A. Mohamed

“…Maintaining antiplatelet therapy potentially increases the risk of recurrent bleeding, while discontinuation heightens susceptibility to ischemic stroke, particularly during the critical first month after hemorrhage. In contemporary practice, physicians demonstrate considerable hesitancy regarding early antiplatelet reinitiation, complicated by the absence of clear evidence-based treatment guidelines. …”
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Implementation of the OHS-interRAI for regular oral health assessments by non-dental caregivers: focus group study using a SWOT analysis by Patricia Ann Ivonne Vandenbulcke, Johanna de Almeida Mello, Florence Marleen Paulien Piccart, Jan De Lepeleire, Emilie Schoebrechts, Anja Declercq, Dominique Declerck, Joke Duyck

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Delivering an Electronic Health Record Based Educational Intervention Promoting Peri-Operative Non-Pharmacological Pain Care as Part of a Randomized Controlled Trial: Mixed Method... by Sarah A Minteer, Cindy Tofthagen, Kathy Sheffield, Susanne Cutshall, Susan Launder, Jane Hein, Mary McGough, Christy M Audeh, Jon C Tilburt, Andrea L Cheville

“… Abstract BackgroundBest practice guidelines recommend educating surgical patients about non-pharmacological pain care (NPPC) techniques that can be used in addition to pain medication for perioperative pain management, given the risks for opioid misuse following surgery. …”
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Assessment of knowledge and perceptions of pharmacy students toward pharmacovigilance activities, and their predictors: a cross-sectional study in Palestine by Rami Mosleh, Mustafa Ghanim, Arwa Omar Al Khatib, Yazun Jarrar, Anas Hamdan, Ruba Balasmeh, Sireen Abdul Rahim Shilbayeh

“…While majority of students (80.8%) recognized the importance of ADRs reporting, substantial gaps were noted in understanding specific practices, such as reporting ADRs from herbal medicines and knowledge of national P.V guidelines. …”
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Telehealth Initiative to Enhance Primary Care Access in Brazil (UBS+Digital Project): Multicenter Prospective Study by Celina de Almeida Lamas, Patrícia Gabriela Santana Alves, Luciano Nader de Araújo, Ana Beatriz de Souza Paes, Ana Claudia Cielo, Luciana Maciel de Almeida Lopes, André Longo Araújo de Melo, Thais Yokoyama, Clarice Pagani Savastano, Paula Gobi Scudeller, Carlos Carvalho

“…Microcosting analysis assessed the project’s economic impact using Brazilian guidelines, with statistical analysis performed using Jamovi software. …”
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Suboptimal maize spacing undermines yields and diminishes land utility in Malawi by Bertha Kachala, Stella Kumwenda, Stella Kumwenda, Annie Matumba, Frank Mnthambala, Zondiwe Mabilabo Jere, Andrew Thadzi, Elija Kamundi, Theresa Nakoma-Ngoma, Evance Chaima, Jean Kamwamba-Mtethiwa, Henry Kankwamba, Amos Ngwira, Maurice Monjerezi, Pieter A. Swanepoel, Jagger Harvey, John F. Leslie, Limbikani Matumba

“…Widespread deviations were driven by excessively wide ridge and intra-row spacing, and by the practice of planting multiple seeds per station (a single sowing point within the row), which introduces intra-station competition and limits yield potential. …”
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Non-invasive ventilation in COVID-19-related acute hypoxemic respiratory failure: a narrative review by Luigi Aronne, Raffaella Pagliaro, Angela Schiattarella, Susan FM Campbell, Maria Vitale, Fabio Perrotta, Klara Komici, Germano Guerra, Andrea Bianco, Filippo Scialò, Vanvitelli - Monaldi COVID Group

“…According to the European Respiratory Society and the American Thoracic Society clinical practice guidelines, NIV is recommended to prevent intubation in hypoxemic acute respiratory failure in patients with community-acquired pneumonia or early acute respiratory distress syndrome without major organ dysfunction. …”
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Achievement of minimal disease activity in psoriatic arthritis according to the time of administration of synthetic disease-modifying antirheumatic drugs, a comparative analysis of... by T. V. Korotaeva, E. Yu. Loginova, E. E. Gubar, Yu. L. Korsakova, M. V. Sedunova, I. N. Pristavsky, I. N. Kushnir, I. F. Umnova, S. S. Kudishina

“…Among sDMARDs, preference is mostly given to the use of MTX in real clinical practice; the treatment with the latter enables 16.5% of patients to achieve MDA. …”
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Prevalence of visual impairment and refractive error-related risk factors in preschool children in beijing, China by Yunyun Sun, Bidan Zhu, Lei Li, Huijian Li, Yuan Qiu, Shana Wang, Xi Qin, Jiantao Cui, Meixia Jiang, Yuanbin Li, Weibin Chen, Jing Fu

“…Visual impairment (VI) was classified according to the Pediatric Eye Evaluations Preferred Practice Pattern guidelines, which define it as presenting visual acuity (PVA) in either eye exceeding 0.4, 0.3, and 0.2 logMAR for respective age groups of 36–47, 48–59, and 60–83 months, and an interocular difference (IOD) of two or more lines in PVA. …”
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An eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Patients With Metastatic Cancers: Protocol for a Randomized Trial by Kimberley T Lee, Briana McLeod, Brian Egleston, Sarah Brown, Sarah Howe, Dominique Fetzer, Lauren Gutstein, Cara Cacioppo, Dana Clark, Susan M Domchek, Jessica Ebrahimzadeh, Dana Falcone, Demetrios Ofidis, Hannah Griffin, Rajia Mim, Santina Hernandez, Linda Fleisher, Kelsey Karpink, Enida Selmani, Aysha Tahsin, Lynne Wagner, Michelle Weinberg, Kuang Yi-Wen, Elisabeth Wood, Angela R Bradbury

“… BackgroundGermline BRCA1 and BRCA2 testing is a standard evidence-based practice, with established risk reduction and cancer screening guidelines for genetic carriers. …”
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Towards the Integration of Additive Manufacturing for Freeform Steel and Glass Façade Construction by Lia Tramontini

“…For the structural node, three different nodes are designed per the design guidelines of selected metal AM methods. The three node prototypes are manufactured, and compared in terms of their fabrication efficiency and material efficiency. …”
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The Bioethics-CSR Divide by Caio Caesar Dib

“…When taken at face value, bioethics may offer guidelines for ethical and socially responsible behavior in the industry, instructing how these should play out in a particular context such as in research, and access to health.[46] When considering the relevance of rewarding mechanisms,[47] bioethics can guide the establishment of certification measures to restore lost trust in the pharmaceutical sector.[48] Furthermore, recognizing that the choice is a more complex matter than the maximization of utility can offer a nuanced perspective on how organizations dealing with existentially relevant choices understand their stakeholders.[49] However, all of those proposals might come with the challenge of proving that something can be gained from its addition to self-regulatory practices[50] within the scope of a dominant rights-based approach to CSR and global and corporate law. …”
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