Characterization of Immune Response Against <i>Mycobacterium marinum</i> Infection in Coho Salmon (<i>Oncorhynchus kisutch</i>) by Le Li, Danlei Xu, Xiaoqing Yu, Chunlei Gai, Haibin Ye, Jing Diao

“…Transcriptome analysis revealed 5028 differentially expressed genes (DEGs) in the kidney and 3419 DEGs in the liver at 6 weeks post-infection. …”
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Genotype-driven sensitivity of mice to tick-borne encephalitis virus correlates with differential host responses in peripheral macrophages and brain by Michaela Berankova, Jiri Holoubek, Vaclav Hönig, Zuzana Matusova, Martin Palus, Jiri Salat, Imtissal Krayem, Jarmila Vojtiskova, Pavel Svoboda, Veronika Pranclova, Lukas Valihrach, Peter Demant, Marie Lipoldova, Daniel Ruzek

“…In addition, brains from these TBEV-infected mouse strains underwent in-depth transcriptomic analysis. Results Virus production in BALB/c and CcS-11 macrophages exhibited similar kinetics 24 and 48 h post-infection (hpi), but CcS-11 macrophages yielded significantly higher titers 72 hpi. …”
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Unlocking the Potential of RNA Sequencing in COVID-19: Toward Accurate Diagnosis and Personalized Medicine by Heba M. Saad Eldien, Abdulrahman H. Almaeen, Ahmed Abo El Fath, Ahmed E. Taha, Rehab Ahmed, Hassabelrasoul Elfadil, Helal F. Hetta

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Comparative transcriptomics of salinomycin molecular toxicity in chicken and turkey by İlksen Berfin Ekinci, Anna Sławińska, Kacper Żukowski, Małgorzata Olejnik

“…This comparative transcriptomic study aimed to determine molecular toxicity mechanisms of Sal in both species. …”
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Jasmonic acid-mediated cell wall biosynthesis pathway involved in pepper (Capsicum annuum) defense response to Ralstonia solanacearum by Xinwei Jiang, Xinyi Liu, Bin Chen, Xiaofen Zhang, Yihao Wang, Ting Wang, Sansheng Geng, Biao Zhu, Heshan Du

“…The number of differentially expressed genes (DEGs) was greater in BVRC1 than in BVRC25 at 12, 24, 48, and 72 h post-infection. JA concentrations were also markedly elevated in BVRC1 in response to R. solanacearum. …”
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Dynamic Coordination of Alternative Splicing and Subgenome Expression Bias Underlies Rusty Root Symptom Response in <i>Panax ginseng</i> by Jing Zhao, Juzuo Li, Xiujuan Lei, Peng Di, Hongwei Xun, Zhibin Zhang, Jian Zhang, Xiangru Meng, Yingping Wang

“…Ginseng rusty root symptoms (GRSs) compromise the yield and quality of <i>Panax ginseng</i>. While transcriptomic analyses have demonstrated extensive remodeling of stress signaling networks, the post-transcriptional defense circuitry remains obscure. …”
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Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeli... by Bingrui Zhu, Changming Liu, Ming Luo, Jiarui Chen, Sixuan Tian, Tiantong Zhan, Yibo Liu, Haocheng Zhang, Zhen Wang, Jianmin Zhang, Yuanjian Fang, Sheng Chen, Xiaoyu Wang

“…We aimed to investigate the meningeal transcriptional response post-SAH and elucidate the dynamic influence of meningeal microenvironment on meningeal lymphatic function. …”
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Host transcriptome profiling for resistance against lumpy skin disease (LSD) by Mohammad Hossein Banabazi, Steven Van Borm, Tomas Klingström, Adnan Niazi, Kris De Clercq, Laurent Mostin, Andy Haegeman, Dirk Jan de Koning

“…The results showed that seven days post-infection may be a critical time point for LSD infection. …”
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IFIT2-induced transcriptomic changes in Mycobacterium tuberculosis infected macrophages by Ewura-Esi Manful, Ray-Dean Pietersen, Bienyameen Baker

“…Using a vector-based overexpression approach, IFIT2 expression was induced in THP-1 cells infected with R179 M. tb, followed by RNA extraction 12 hours post-infection and AmpliSeq-based targeted transcriptome sequencing. …”
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Transcriptome atlas of Striga germination: Implications for managing an intractable parasitic plant by Gilles Irafasha, Sylvia Mutinda, Fredrick Mobegi, Brett Hale, George Omwenga, Asela J. Wijeratne, Susann Wicke, Emily S. Bellis, Steven Runo

“…They only germinate in response to biomolecules emitted from the host's root exudate, strigolactones (SL). …”
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Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis by Zhihua Ou, Li Li, Peidi Ren, Ting‐Ting Zhou, Fan He, Jialing Chen, Huimin Cai, Xiumin Han, Yao‐Dong Wu, Jiandong Li, Xiu‐Rong Li, Qiming Tan, Wenhui Li, Qi Chen, Nian‐Zhang Zhang, Xiuju He, Wei‐Gang Chen, Yanping Zhao, Jiwen Sun, Qian Zhang, Yan‐Tao Wu, Yingan Liang, Jie You, Guohai Hu, Xue‐Qi Tian, Sha Liao, Bao‐Quan Fu, Ao Chen, Xue‐Peng Cai, Huanming Yang, Jian Wang, Xin Jin, Xun Xu, Wan‐Zhong Jia, Junhua Li, Hong‐Bin Yan

“…Herein, bulk RNA‐seq, scRNA‐seq, and spatial transcriptomics technologies are integrated, to reveal the host immune response mechanism against E. multilocularis both spatially and chronologically, collecting mouse liver samples at multiple timepoints up to 15 months post infection. …”
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Unique lymphocyte transcriptomic profiles in septic patients with chronic critical illness by Evan L. Barrios, Leandro Balzano-Nogueira, Valerie E. Polcz, Christine Rodhouse, Jack R. Leary, Dijoia B. Darden, Jaimar C. Rincon, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Shawn D. Larson, Ashish Sharma, Gilburt Upchurch, Shannon M. Wallet, Todd M. Brusko, Todd M. Brusko, Tyler J. Loftus, Alicia M. Mohr, Robert Maile, Rhonda Bacher, Rhonda Bacher, Guoshuai Cai, Michael P. Kladde, Clayton E. Mathews, Lyle L. Moldawer, Maigan A. Brusko, Maigan A. Brusko, Philip A. Efron

“…IntroductionDespite continued improvement in post-sepsis survival, long term morbidity and mortality remain high. …”
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Gene expression profiling in pure neural leprosy: insights into pathogenesis and diagnostic biomarkers by Mariana Martins de Athaide, Thyago Leal-Calvo, Tatiana Pereira Da Silva, Thabatta Leal Silveira Andrezo Rosa, Helen Ferreira, Bernardo Miguel de Oliveira Pascarelli, Ana Caroline Siquara de Sousa, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Roberta Olmo Pinheiro, Roberta Olmo Pinheiro, Roberta Olmo Pinheiro

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Courtship Is a Major Factor of Mating‐Shortened Male Lifespan in an Egg Parasitoid by Zi‐Yin Wang, Jing Li, Jia‐Min Tang, Lan‐Feng Qiu, Hao‐Yuan Hu, Peng‐Cheng Liu

“…Many studies on insects have reported a decreased post‐mating lifespan, and studies on the effects of mating on longevity have focused mainly on females. …”
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Human transcriptional signature of protection after Plasmodium falciparum immunization and infectious challenge via mosquito bites by Marie Mura, Burook Misganaw, Aarti Gautam, Tanisha Robinson, Sidhartha Chaudhury, Neha Bansal, Andrew J. Martins, John Tsang, Rasha Hammamieh, Elke Bergmann-Leitner

“…Analyzing longitudinal time points not only post-vaccination but also post-controlled human malaria infection further revealed that the transcriptomic profile of protected vs non-protected individuals was not static but continued to diverge over time. …”
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Comparative transcriptome analysis in two contrasting genotypes for Sclerotinia sclerotiorum resistance in sunflower. by Mingzhu Zhao, Bing Yi, Xiaohong Liu, Dexing Wang, Dianxiu Song, Enyu Sun, Liangji Cui, Jingang Liu, Liangshan Feng

“…Here, a comparative transcriptomic analysis was performed in leaves of two contrasting sunflower genotypes, disease susceptible (DS) B728 and disease resistant (DR) C6 after S. sclerotiorum inoculation. …”
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Characteristics of transcriptome and chromatin accessibility in the peripheral blood after acute hypoxia exposure by Kuo Zeng, Pei-ru Yuan, Jin-feng Xuan, Lai-xi Zhao, Xiao-na Li, Jun Yao, Dong Zhao

“…Results Hence, we performed RNA sequencing (RNA-seq) and ATAC sequencing (ATAC-seq) to observe the changes of transcriptome and chromatin accessibility in the peripheral blood of eight individuals at 1 h post adaptation in a simulated plateau environment with 3500 m and 4500 m altitude, respectively. …”
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Spatial Transcriptomic Signatures of Early Acute T Cell–mediated Rejection in Kidney Transplants by Minji Kang, BS, Haeyoon Kwon, Jeongin Song, BS, Yunyoung Jang, BS, Seung Hee Yang, PhD, Seung-Min Cha, BS, Ji Hwan Moon, PhD, Yong Chul Kim, MD, PhD, Hyun Je Kim, MD, PhD

“…Immunofluorescence staining for CD68 confirmed the presence of macrophages in the glomeruli of the post-TCMR sample in a validation cohort, indicating macrophage involvement in the glomerular response after TCMR. …”
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Preweaning heat stress alters liver transcriptome and DNA methylation in dairy calves by Jimena Laporta, Bethany Dado-Senn, Anne R. Guadagnin, Lihe Liu, Francisco Peñagaricano

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ABA-induced alternative splicing drives transcriptomic reprogramming for drought tolerance in barley by Anna Collin, Hubert Matkowski, Ewa Sybilska, Asmarany Biantari, Oliwia Król, Agata Daszkowska-Golec

“…At the molecular level, ABA priming accelerates stress-response pathways, promoting alternative splicing, isoform switching, and chromatin modifications that enable transcriptome plasticity. …”
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