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Effectiveness, safety and costs of the FreeStyle Libre glucose monitoring system for children and adolescents with type 1 diabetes in Spain: a prospective, uncontrolled, pre-post s...
Published 2023-12-01“…Objectives This study aimed to evaluate the effectiveness, safety and costs of FreeStyle Libre (FSL) glucose monitoring system for children and adolescents with type 1 diabetes mellitus (T1DM) in Spain.Design Prospective, multicentre pre-post study.Setting Thirteen Spanish public hospitals recruited patients from January 2019 to March 2020, with a 12-month follow-up.Participants 156 patients were included.Primary and secondary outcome measures Primary: glycated haemoglobin (HbA1c) change. …”
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Knowledge, attitude and determinants of post-abortion contraceptive use among women of reproductive age seeking care in healthcare facilities in Ile-Ife, Nigeria: a cross-sectional...
Published 2025-05-01“…It is a key strategy for the reduction of unintended pregnancies and repeated abortion.Objective The study aimed to assess the knowledge and attitude towards post-abortion contraception and examine the determinants of post-abortion contraceptive use among women of reproductive age seeking care in healthcare facilities in Ile-Ife.Design The study was a facility-based descriptive cross-sectional survey which employed a quantitative method.Method The study was conducted among women of reproductive age who have had abortion and are seeking care in the family planning units of healthcare facilities in Ile- Ife. 285 respondents were recruited for the study using a two-stage sampling technique. …”
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Effects of intermittent theta burst stimulation versus repetitive transcranial magnetic stimulation on post-stroke dysphagia in hospitalised patients: study protocol for a prospect...
Published 2025-04-01“…There are few studies comparing iTBS with 10 Hz rTMS in the treatment of post-stroke dysphagia (PSD). Therefore, our study describes the rationale and design of a randomised controlled trial to evaluate the effects of iTBS versus 10 Hz rTMS on swallowing function, serum indexes and functional fMRI in patients with PSD.Methods and analysis Fifty participants with PSD will be randomly assigned to the iTBS group (n=25) or the rTMS group (n=25). iTBS group: three 50 Hz pulses, repeated at 5 Hz, 100% intensity threshold, 600 pulses/time and sham rTMS. rTMS group: 10 Hz pulse, 100% intensity threshold, 1000 pulses/time and sham iTBS. …”
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Short-term outcome and predictors of post-operative complications following transurethral resection of the prostate among patients with benign prostate hyperplasia in Northern Tanz...
Published 2025-05-01“…This study aimed to assess the short-term outcomes of TURP and identify factors associated with post-operative complications among patients with BPH in Northern Tanzania. …”
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Sheffield Adaptive Patterned Electrical Stimulation (SHAPES) Therapy for Post Stroke Arm spasticity: study protocol for a 3-arm, a partially blinded, randomised controlled trial
Published 2024-11-01“…Abstract Introduction Post stroke elbow spasticity (PSES) affects over a third of individuals following stroke and negatively impacts on functional recovery, comfort and quality of life. …”
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Step up to triple therapy versus switch to dual bronchodilator therapy in patients with COPD on an inhaled corticosteroid/long-acting β2-agonist: post-hoc analyses of KRONOS
Published 2025-05-01“…In participants without a recent exacerbation history on ICS/LABA in the 30 days before screening, morning pre-dose trough FEV1 change from baseline and moderate/severe exacerbation rates over 24 weeks were analyzed post-hoc using linear repeated measures models and negative binomial regression, respectively, and participants escalated to ICS/LAMA/LABA (BGF) were compared with those switching to LAMA/LABA (GFF) or staying on ICS/LABA (BFF or BUD/FORM). …”
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The N17 domain of huntingtin as a multifaceted player in Huntington’s disease
Published 2025-01-01“…Huntington’s disease (HD) is primarily caused by the aberrant aggregation of the N-terminal exon 1 fragment of mutant huntingtin protein (mHttex1) with expanded polyglutamine (polyQ) repeats in neurons. The first 17 amino acids of the N-terminus of Httex1 (N17 domain) immediately preceding the polyQ repeat domain are evolutionarily conserved across vertebrates and play multifaceted roles in the pathogenesis of HD. …”
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Molecular Mechanisms of Protein Aggregation in ALS-FTD: Focus on TDP-43 and Cellular Protective Responses
Published 2025-05-01“…Moreover, this review describes the protective mechanisms activated by the cells to prevent protein aggregation, including molecular chaperones and post-translational modifications (PTMs). Understanding these regulatory pathways could offer new insights into targeted interventions aimed at mitigating cell toxicity and restoring cellular function.…”
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Effect of an Intra-Sets Variable Resistance Potentiation Protocol on Throwing Speed in Elite Female Handball Players
Published 2025-03-01“…The aim of this study was to analyze the effects of a post-activation performance enhancement (PAPE) protocol with functional electro-mechanical dynamometry (FEMD) on throwing velocity. …”
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Za hranice feministických diskusí mezi Východem a Západem
Published 2012-12-01“…The paper aims to critically analyze the construction of feminist East/West debates in the context of the anthology Gender Politics and Post-Communism (Funk, Mueller 1993). It does so from the perspective of other critical feminist voices as well as global power relations, taking effect in the international feminist academic community. …”
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A comparison of artificial urinary sphincter outcomes after primary implantation and first revision surgery
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Effects of force- and velocity-oriented conditioning activities on jump height in strength-deficient male participants
Published 2025-03-01“…JH was measured at baseline and 3, 6, and 9 min post-CA.ResultsA three-way (group × condition × time) repeated measures ANOVA revealed significant effects of time (F = 7.78; partial-η2 = 0.14; p < 0.01) and a significant condition × time interaction (F = 16.57; partial-η2 = 0.26; p < 0.01) for JH. …”
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Acute effects of isometric conditioning activity with different distribution contraction on countermovement jump performance in resistance trained participants
Published 2025-05-01“…Post-hoc comparisons indicated a significant decrease in CMJ height at the 9th minute compared to the 3rd minute (35.7 ± 5.6 cm vs. 36.8 ± 5.5 cm post-CA; d = 0.161; p = 0.048). …”
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Why do most young women not take up contraceptives after post-abortion care? An ethnographic study on the effectiveness and quality of contraceptive counselling after PAC in Kilifi...
Published 2023-12-01“…Post-abortion care (PAC) counselling and the provision of contraceptive methods are core components of PAC services. …”
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Targeted NMDA receptor knockdown in recall‐activated neuronal ensembles impairs remote fear extinction
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Effect of Safinamide on Non-Motor Symptoms and Quality of Life in Parkinson’s Disease Patients According to Sex, Age, Disease Duration and Levodopa Equivalent Daily Dose
Published 2025-06-01“…<b>Background and objective:</b> Safinamide can improve the non-motor symptoms (NMSs) and quality of life (QoL) in patients with Parkinson’s disease (PD). In this post hoc analysis of the SAFINONMOTOR study, we analyzed the effect of safinamide on NMSs and QoL according to age, sex, disease duration (DD), and levodopa equivalent daily dose (LEDD). …”
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Pretreatment with an anti-CGRP monoclonal antibody attenuates mild TBI-induced tactile hypersensitivity in mice
Published 2025-08-01“…Abstract Background Post-traumatic headache (PTH) can develop following a mild traumatic brain injury (mTBI), such as a concussion. …”
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