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  1. 521

    A dataset of transcriptomic effects of camptothecin treatment on early zebrafish embryosGene Expression Omnibus by Sergey V. Prykhozhij, Kevin Ban, Zane L. Brown, Kim Kobar, Gabriel Wajnberg, Charlotte Fuller, Simi Chacko, Jacynthe Lacroix, Nicolas Crapoulet, Craig Midgen, Adam Shlien, David Malkin, Jason N. Berman

    Published 2024-12-01
    “…We treated wild-type and miR-34a deletion mutant zebrafish embryos at 24 h post-fertilization with 1 µM of the topoisomerase I inhibitor, camptothecin (CPT), for 4 h to catalogue gene expression changes induced by this DNA damage treatment and to understand if these changes are influenced by loss of miR-34a. …”
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  2. 522
  3. 523

    Developing a contextually and culturally relevant benefit-sharing framework for pathogen genomic research and biobanking in africa: a deliberative expert approach by Pamela Emefa Selormey, Irene H. Tsey, John Ganle, Patricia Akweongo, Paulina Tindana

    Published 2025-07-01
    “…The first phase presents the contextual benefit-sharing process, which includes the benefit-sharing process, iterative benefit-sharing cycles and post-benefit-sharing responsibilities. …”
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  4. 524

    The impact of COVID-19 on young people's mental health, wellbeing and routine from a European perspective: A co-produced qualitative systematic review. by Lindsay H Dewa, Lily Roberts, Elizabeth Choong, Caroline Crandell, Ola Demkowicz, Emma Ashworth, Catia Branquinho, Steph Scott

    Published 2024-01-01
    “…However, YP identified potential issues in these areas going forward, and therefore stressed the importance of ongoing long-term support in education, learning and mental health post-Covid-19.<h4>Conclusions</h4>Our findings map onto the complex picture seen from quantitative systematic reviews regarding the impact of Covid-19 on YP's mental health. …”
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  5. 525

    Paleogeographic numerical modeling of marginal seas for the Holocene – an exemplary study of the Baltic Sea by J. Miluch, J. Miluch, W. Zhang, J. Harff, A. Groh, P. Arlinghaus, C. Denker

    Published 2025-04-01
    “…Consistent paleogeographic reconstructions at a marginal sea scale considering the global, regional, and local processes are yet to be derived, and this study presents an effort towards this goal. …”
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  6. 526

    Herpes simplex virus-induced upregulation of inflammatory cytokines in human gingival fibroblasts by Yu Zhang, Kalam Lo, Chunmei Wang, Guoliang Zhou, Xiping Feng, Jing Ni, Xi Chen

    Published 2024-12-01
    “…Next, the prominent activation of TLRs, retinoic acid-inducible gene I-like receptor signaling, NLRs, and downstream IFNAR-JAK-STAT signaling pathways were observed via a modified HSV-1 infection map. The HSV-1-induced upregulation of inflammatory cytokines in HGFs may drive inflammatory processes in periodontitis. …”
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  7. 527
  8. 528

    Analysis of failure mechanisms and behavior of LiCoO2-graphite batteries at 0 ℃ by Ke Li, Jia Niu, Yifan Hao, Jiaxin Yao, Pushpendra Kumar, Zhenhao Luo, Songtong Zhang, Jing Wang, Xiayu Zhu, Wenjie Meng, Jingyi Qiu, Guiling Wang, Hai Ming

    Published 2025-07-01
    “…The key factors for achieving a moderate desolvation process involve constructing a Li+ solvation shell characterized by weak interactions between Li+ and the solvents. …”
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  9. 529

    Back pain exercise therapy remodels human epigenetic profiles in buccal and human peripheral blood mononuclear cells: an exploratory study in young male participants by Claire Burny, Mia Potočnjak, Mia Potočnjak, Annika Hestermann, Sophie Gartemann, Michael Hollmann, Frank Schifferdecker-Hoch, Nina Markanovic, Simone Di Sanzo, Simone Di Sanzo, Michael Günsel, Victor Solis-Mezarino, Moritz Voelker-Albert, Moritz Voelker-Albert

    Published 2024-10-01
    “…We also performed an exploratory analysis to confirm the usability of molecular profiles in (1) mapping lifestyle choices and (2) evaluating the distance of a given participant to an optimal health state.ConclusionThis pre-post cohort study highlights the potential of integrated molecular profiles to score therapy efficiency. …”
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  10. 530

    Identification and Mechanistic Studies of Key Genes in Thalamic Hemorrhage Pain by Multi-omics by Chen Yang, Ju Gao, Yaqun Li, Yinggang Xiao, Tianfeng Huang

    Published 2025-07-01
    “…Background: Thalamic hemorrhage pain (THP), a subtype of central post-stroke pain (CPSP), commonly develops following ischemic or hemorrhagic injury to the thalamus. …”
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  11. 531

    Occurrence characteristics and utilization potential of scarce coking coal resources in Huaibei coalfield by Run ZHAN, Wenyong ZHANG, Feng HAN, Fengtang SUI, Jiayi GU, Guijian LIU, Tian ZHAO

    Published 2025-02-01
    “…The Huaibei Coalfield in Anhui Province, as one of the first key mining areas of scarce coking coal set up by the state, has rich resources and excellent coal quality, and is the most promising coking coal resource source in East China.In order to systematically understand the occurrence characteristics and exploitation and utilization potential of scarce coking coal in the study area, this paper reveals the spatio-temporal difference characteristics, formation control factors and resource potential of scarce coking coal in the study area through coal rock analysis, industrial coal quality index test, comprehensive mapping and resource evaluation, using previous drilling data and underground supplementary sampling tests.The results show that the scarce coking coal in Huaibei coalfield is well developed, and the floating coal after washing shows the characteristics of ultra−low water, ultra−low ash, ultra−low sulfur, ultra−low fixed carbon, medium and high volatile, and has the process properties of medium−strong bonding and coking, low potassium and sodium content, and good mechanical strength and thermal strength.The scarce coking coal is controlled by the regional structure and the sedimentary distribution of coal seams, and the coal seams of Xiashihezi Formation 7 and 8 are the most developed. …”
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  13. 533

    Evidence adaptation and tailored implementation of family bereavement support in specialised palliative care: A multi-method study by Myrta Kohler, Qëndresa Thaqi, Silke Kuske, Torsten Schwalbach, Marco Riguzzi, Rahel Naef

    Published 2025-06-01
    “…Drawing on implementation mapping methodology, a systematic and participatory process was used to develop an implementation plan that specified activities needed to address identified barriers and support integration into palliative care services. …”
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  14. 534
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  16. 536

    The m6A modification regulates the composition of myofiber types in chicken skeletal muscle by Yanju Shan, Yifan Liu, Ming Zhang, Lichuan Pang, Gaige Ji, Xiaojun Ju, Yunjie Tu, Jingting Shu

    Published 2025-03-01
    “…To investigate the post-transcriptional modification underlying the myofiber type diversity in chicken skeletal muscle, we evaluated the m6A methylation levels of chicken skeletal muscles with different phenotypic traits, and profiled a transcriptome-wide m6A map in the oxidative and glycolytic skeletal muscles by methylated RNA immunoprecipitation sequencing (MeRIP-seq). …”
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  17. 537

    Bibliometric-based visualization analysis of hotspots and trends in falls research among older hospitalized patients (2013–2023) by Yang Dong, Dandan Liu, Ya Yu, Ziyu Xiong, Hongying Rao

    Published 2025-03-01
    “…Furthermore, epidemiology, aging population dynamics, and health outcomes continue to be enduring areas of interest for researchers post-2018 and warrant additional emphasis from scholars.…”
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  18. 538
  19. 539

    Modelling the liver’s regenerative capacity across different clinical conditions by Anh Thu Nguyen-Lefebvre, Soumita Ghosh, Cristina Baciu, Bima J. Hasjim, Sara Naimimohasses, Graziano Oldani, Elisa Pasini, Michael Brudno, Nazia Selzner, Jeffrey Wrana, Mamatha Bhat

    Published 2025-08-01
    “…Background &amp; Aims: Liver regeneration is essential for recovery following injury, but this process can be impaired by factors such as sex, age, metabolic disorders, fibrosis, and immunosuppressive therapies. …”
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  20. 540