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481
Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε.
Published 2010-11-01“…In their absence, a defective replisome may more frequently leave gaps on the leading strand that are eventually filled by Pol ζ or Pol δ, in a post-replication process that generates errors not corrected by the DNA mismatch repair system.…”
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482
Dietary transformations and health implications in migrant populations: a global perspective
Published 2025-08-01“…After applying inclusion and exclusion criteria, 30 studies directly addressing dietary change and health outcomes post-migration were included. Key themes were identified through iterative synthesis.ResultsEvidence indicates a consistent trend of dietary acculturation across diverse migrant groups, typically involving increased consumption of energy-dense, processed foods (a 15–20% increase) and decreased intake of traditional staples such as whole grains (down by 10–15%), pulses, and fresh vegetables. …”
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483
Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: a mixed-methods systematic review
Published 2025-02-01“…Our patient and public representatives were consulted throughout the process. Systematic review and meta-analysis Our systematic review included randomised controlled trials (RCTs) and non-randomised controlled trials (controlled and uncontrolled pre–post studies and case-control studies) of lifestyle modification interventions for adults with learning disabilities. …”
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484
Towards the Rational Use of Plastic Packaging to Reduce Microplastic Pollution: A Mini Review
Published 2025-06-01“…Emphasis is placed on the cradle-to-grave lifecycle of plastic materials, highlighting how poor design, excessive packaging, and inadequate post-consumer treatment contribute to MP release. …”
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485
Gender Equality and Sustainability in Vietnamese Higher Education: Educators’ Perspectives
Published 2025-04-01“…Despite existing policies promoting gender equality, gaps persist in leadership and career development, potentially limiting women’s representation and growth. …”
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486
Toward Adaptive and Immune-Inspired Viable Supply Chains: A PRISMA Systematic Review of Mathematical Modeling Trends
Published 2025-07-01“…Descriptive analysis revealed a significant increase in scientific output starting in 2020, driven by post-pandemic concerns and the accelerated digitalization of logistics operations. …”
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487
Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies
Published 2025-06-01“…ABSTRACT Lactylation, a recently identified post‐translational modification, represents a groundbreaking addition to the epigenetic landscape, revealing its pivotal role in gene regulation and metabolic adaptation. …”
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488
Job recommender systems: a systematic literature review, applications, open issues, and challenges
Published 2025-06-01“…Over the past 13 years, JRS studies have explored a variety of themes, including recommending suitable team members, identifying training modules based on skill gaps, developing career path planning systems, assessing employee satisfaction, standardizing professional knowledge, analyzing job postings to determine the busiest job fields, and estimating job tenure and turnover intention. …”
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489
piRNA/PIWI pathways and epigenetic crosstalk in human diseases: Molecular insights into HIV-1 infection and drugs of abuse
Published 2025-03-01“…Special attention is given to the role of piRNA/PIWI complexes in regulating gene transcription, translation, and post-translational modifications in the context of disease. …”
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490
Long-term Neurological Consequences of COVID-19 in Patients With Pre-existing Alzheimer’s and Parkinson’s Disease: A Comprehensive Review
Published 2025-05-01“…Clinical studies reporting cognitive and motor dysfunctions in post-COVID-19 patients with pre-existing neurodegenerative diseases are also summarized. …”
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491
Bibliometric Analysis of Medical Waste Research Using Python-Driven Algorithm
Published 2025-05-01“…Despite advancements, gaps remain in adopting sustainable waste disposal practices, with limited bibliometric analysis in this field. …”
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492
Patient-Reported Experiences in Vascular Surgery: A Qualitative Analysis of Care Quality
Published 2025-06-01“…Results: Six themes were identified: (i) communication and information delivery, (ii) patient involvement in decision-making, (iii) pain management, (iv) psychological and emotional support, (v) healthcare environment and systemic processes and (vi) continuity of care and post-discharge experience. …”
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493
Integrating a culturally adapted mental health intervention within entrepreneurship training for displaced youth in Colombia: a pilot randomized controlled trial
Published 2025-07-01“…Quantitative data on mental health outcomes was collected at baseline, post-intervention and 6-month follow-up. Qualitative data was analyzed using an open-coding process. …”
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494
Research Progress on the Functional Regulation Mechanisms of ZKSCAN3
Published 2025-07-01“…The zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3) has emerged as a critical regulator of diverse cellular processes, including autophagy, cell cycle progression, and tumorigenesis. …”
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495
Strategy 2020: New Outlines of Russian Innovation Policy
Published 2011-12-01“…The experts propose three possible scenarios, as follows: the inertial scenario, which implies low rates of economic growth while preserving the dependence of the economy on extractive industries; the progressive scenario, which presumes the accelerated integration into global processes and transition to the post-industrial model, and the moderate scenario, which has the highest probability of realization. …”
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496
Electron Beam Irradiation’s Effect on Polyaniline/LiClO<sub>4</sub>/CuO Nanocomposite: A Study of Dielectric, Conductivity and Electrochemical Properties
Published 2025-04-01“…A straightforward chemical polymerization process was used to create the polyaniline/LiClO<sub>4</sub>/CuO nanoparticle (PLC) nanocomposite, which was then exposed to varying doses of electron beam (EB) radiation and studied. …”
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497
Developing emergency medical care policy across Kenya: A framework for policy development
Published 2024-12-01“…Growth and improvement will be measured post-implementation based on baseline EMC metrics. …”
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498
Can generative AI Be an effective Co-Teacher? An experiment
Published 2025-06-01“…Employing an experimental methodology with the 400 participants of control and experimental groups, the study utilized pre-test and post-test evaluations, stratified sampling, and impartial reviews of prepared scripts. …”
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499
Assessing the quality of AI information from ChatGPT regarding oral surgery, preventive dentistry, and oral cancer: An exploration study
Published 2024-11-01“…Results: While achieving the highest score for preventive dentistry at 4.3/5 and being able to communicate the complex information coherently, the tool showed lower accuracy for oral surgery and oral cancer, scoring 3.9/5 and 3.6/5, respectively, with several gaps for post-operative instructions, personalized risk assessments, and specialized diagnostic methods. …”
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500
Rethinking the Impact of Single Continuing Educational Activities: Navigating Complexity Through Insights from Real-World Evaluation and Contemporary Literature
Published 2025-12-01“…However, providers may also choose some more targeted approaches to influence the mindset even in heterogeneous learner groups:- integrating not only knowledge and competence but also current performance gaps into pre-/post-tests- increasing opportunities for discussion will allow optimal matching of the individual needs of participants with the CE content. …”
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