Physical activity interventions in adult kidney transplant recipients: an updated systematic review and meta-analysis of randomized controlled trials by Roseanne E. Billany, Nicolette C. Bishop, Ellen M. Castle, Matthew P. M. Graham-Brown, Sharlene A. Greenwood, Courtney J. Lightfoot, Thomas J. Wilkinson

“…Therefore, this updated review and meta-analysis includes 23 RCTs. Outcomes included cardiorespiratory fitness (CRF), strength, blood pressure, body composition, heart rate, markers of dyslipidemia and kidney function, and health-related quality of life.Results Twenty-three RCTs, including 1,139 KTRs, were included. …”
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Multi-region brain transcriptomic analysis of amyotrophic lateral sclerosis reveals widespread RNA alterations and substantial cerebellum involvement by Natalie Grima, Andrew N. Smith, Claire E. Shepherd, Lyndal Henden, Thiri Zaw, Luke Carroll, Dominic B. Rowe, Matthew C. Kiernan, Ian P. Blair, Kelly L. Williams

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Spine Fractures in Ankylosing Spondylitis Patients: Analysis of Fracture Pattern, Clinical, and Radiological Outcome: A Retrospective Observational Study by Shreya P Shenoy, Delhibabu B Thamba, Subhadeep Ghosh, CS Vishnu Prasath, V Venkatasujith

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Effects of the different intensities of task-oriented training on the upper extremity motor function and self-care ability of stroke survivors: study protocol for a multiarm parall... by Kai Zhang, Chunxiang Li, Shengfeng Liu, Xuecha Li, Mengsi Peng

“…Therefore, this study aims to explore the effects of different intensities of TOT on motor function and self-care ability of stroke survivors.Methods and analysis This randomised controlled clinical trial will recruit 72 participants from a tertiary hospital, diagnosed with decreased self-care ability and upper limb motor dysfunction post-stroke. …”
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Bioelectrical impedance analysis–derived phase angle predicts possible Sarcopenia in patients on maintenance hemodialysis: a retrospective study by Ying Zeng, Yang Chen, Yujie Yang, Ying Qiu, Ping Fu, Huaihong Yuan

“…Measurements were taken post-dialysis to ensure consistency. The whole-body phase angle was measured using the InBody S10 device, grip strength was measured using an electronic grip strength tester, and physical function was assessed by the Short Physical Performance Battery (SPPB). …”
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Identifying lifelong factors that impact brain health and functional outcomes in adults with childhood-onset type 1 diabetes: the cognition and longitudinal assessments of risk fac... by Velandai K Srikanth, Eva L Feldman, Chris Moran, Lili Zhao, Amy Brown, Richard Beare, Elisabeth A Northam, Emily J Koubek, Stacey A Sakowski, Taya Collyer, Chris L. Adamson, Fergus J. Cameron

“…We now introduce the Cognition and Longitudinal Assessments of Risk Factors over 30 Years (CLARiFY) Diabetes Complications Study to assess brain, cognition and functional outcomes in mid-adulthood, approximately 30 years post-T1D onset. …”
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Comparative efficacy of conservative interventions for adolescent idiopathic scoliosis: a systematic review and network meta-analysis of randomized controlled trials by Jun Ren, Shoujian Wang, Miaoxiu Li, Xin Zhou, Ya Wen, Zonglin Wen, Jiannan Lin, Lingjun Kong, Min Fang

“…Brace plus physiotherapeutic scoliosis-specific exercises (PSSE, mean difference (MD): 4.80, 95% confidence interval (CI): 0.56 to 9.04, moderate certainty), manual therapy plus PSSE (MD: 5.26, 95% CI: 1.09 to 9.43, moderate certainty), and manual therapy plus mind–body exercise (MD: 5.14, 95% CI: 1.25 to 9.04, moderate certainty) could be intermediately effective in improving Cobb angle of patients with AIS at post-interventions. Although brace alone (MD: 1.53, 95% CI: 1.09 to 2.14, high certainty) could be the intermediate effective intervention in preventing scoliosis progression, moderate to high certainty evidence showed that brace alone and PSSE alone probably have little or no difference in improving Cobb angle, function, mental health, self-image, angle of trunk rotation (ATR), or satisfaction of patients with AIS compared to minimal interventions. …”
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Survival outcomes and prognostic factors of breast cancer spinal metastases: a retrospective study by Panpan Hu, Xin Wu, Yan Li, Feng Wei, Shengxin Zeng, Yu Xiao, Xiaoguang Liu, Zhongjun Liu

“…Kaplan–Meier survival curves were plotted. Univariate analysis employed the log-rank test, and post-hoc multivariate analysis utilized the Cox regression model. …”
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Molecular Genetic Analysis of a DMD Frameshift Mutation in a Boy with Duchenne Muscular Dystrophy by MLPA and Sanger Sequencing by Chen Q, Zhang W, Zha L

“…The deletion of those four nucleotides resulted in a frameshift mutation and a premature nonsense codon, which resulted in a truncated dystrophin that lost its most critical function and underwent post-transcriptional degradation. …”
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Characteristic parameter analysis of magnetic resonance diffusion tensor imaging in children with autism spectrum disorder: a retrospective study by Qianfang Jia, Xiaofang Wang, Xiwan Li, Shasha Li, Ming Wang, Luping Wang, Bingxiang Ma, Meng Zhang

“…A 32-channel cranial nerve coil of a GE Signa HDxt 3.0T magnetic resonance system was used for the examination, and the FA and ADC maps were obtained by post-processing the DTI raw diffusion images with the Functool function software in the workstation. …”
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Thermal processing and geographical origin as drivers of terpenoids variation in Anethum graveolens L. essential oils: A biplot analysis. by Karim Farmanpour Kalalagh, Mehdi Mohebodini, Naser Sabaghnia, Arman Beyraghdar Kashkooli, Hassan Esmaeili

“….), a medicinal-vegetable plant renowned for its aromatic and functional properties, exhibits significant variation in essential oil composition due to geographical origin (genotypic diversity) and post-harvest drying temperatures (DTs). …”
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Clinical Evidence of Mesenchymal Stromal Cells for Cerebral Palsy: Scoping Review with Meta-Analysis of Efficacy in Gross Motor Outcomes by Madison C. B. Paton, Alexandra R. Griffin, Remy Blatch-Williams, Annabel Webb, Frances Verter, Pedro S. Couto, Alexey Bersenev, Russell C. Dale, Himanshu Popat, Iona Novak, Megan Finch-Edmondson

“…We conducted a scoping review of published and registered reports of MSC treatment for CP, with meta-analysis of Gross Motor Function Measure (GMFM) outcomes to summarize research and provide future recommendations. …”
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The Spatial-Temporal Canvas That We Call the Stage: Text and Performance in Final Solutions by Ananya Ghoshal, Manivendra Kumar

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Comprehensive Identification and Unveiling Key Nitrate-Transporting Proteins in Oat (Avena sativa L.) by Rong Cheng, Qiang Xiao, Jie Gong, Renwei Sun, Yinke Du, Wei Zhao, Wei Zheng, Shiqing Gao

“…However, AsNPF7.16 and AsNPF7.19 were both highly expressed in the roots at 9 h post-LN treatment but exhibited low expression in the leaves. …”
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Clustering analysis of volatile organic compound biomarkers with tobacco exposure and the association with cardiovascular health outcomes in an observation study cohort by Juan Zhao, Haoyun Hong, Joseph Zhai, Remy Poudel, Sanjay Srivastava, Andrew C. Stokes, Pawel K. Lorkiewicz, Tian Jiang, Rose Marie Robertson, Aruni Bhatnagar, Jennifer L. Hall, Naomi M. Hamburg, Rachel J. Keith

“…VOC metabolites were analyzed in urine onehour post-use of a tobacco product via ultraperformance liquid chromatography. …”
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Exploration of autophagy-associated genes and potential molecular mechanisms in type 1 diabetes and osteoporosis by Houyuan Wang, JiaCong Xiao, Caixia Fu, JIzhi Ma, Ziwei Jiang

“…Machine learning (LASSO/Random Forest) prioritized CPNE1 and FRAT2, validated through ROC curve analysis. Functional annotation via GO/KEGG enrichment analyses revealed enrichment in disease-associated pathways, corroborated by immune infiltration profiling and single-cell RNA sequencing showing cell-type-specific expression patterns. miRNA-gene regulatory networks further elucidated post-transcriptional control mechanisms. …”
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Optimal Systolic Blood Pressure Control After Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-analysis by Baikuntha Panigrahi, Rohit Bhatia, Partha Haldar, Risha Sarkar, Imnameren Longkumer

“…This study aimed to determine whether intensive SBP control (<140 mmHg) within 24 h post-EVT, compared to conventional management (<180 mmHg), leads to a better functional outcome, defined as a modified Rankin Scale (mRS) score of 0–2 at 90 days. …”
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Efficacy of RADA16-Based Self-Assembling Peptides on Wound Healing: A Meta-Analysis of Preclinical Animal Studies by Jiaju Lu, Liuting Chen, Zeyue Sun, Zhimou Yang

“…The primary outcome, wound closure rate at 7 and 14 days post-injury, was pooled using a random-effects meta-analysis. …”
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Analysis of the venom components of necrotic tissue exudates from Naja atra venom-infected Guangxi Bama miniature pigs by XIAO Manqi, GUAN Zhezhe, HU Shaocong, LI Yalan, ZHANG Ziyan, JIANG Ningjing, ZHANG Xuerong, LIAO Ming

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Machine learning cluster analysis identifies increased 12-month mortality risk in transcatheter aortic valve replacement recipients by Thomas Meredith, Thomas Meredith, Thomas Meredith, Farhan Mohammed, Amy Pomeroy, Sebastiano Barbieri, Sebastiano Barbieri, Erik Meijering, Louisa Jorm, David Roy, Jason Kovacic, Jason Kovacic, Jason Kovacic, Jason Kovacic, Michael Feneley, Michael Feneley, Michael Feneley, Christopher Hayward, Christopher Hayward, Christopher Hayward, David Muller, David Muller, David Muller, Mayooran Namasivayam, Mayooran Namasivayam, Mayooran Namasivayam

“…Nested cox models were used to identify any incremental prognostic benefit cluster assignment achieved beyond conventional risk scores.ResultsAnalysis identified two distinct clusters. Compared to Cluster 1, Cluster 2 demonstrated significantly worse all-cause mortality at 12 months (HR 6.3, p &lt; 0.01), and was characterised by more advanced cardiac remodelling with worse indices of multi-chamber cardiac function, as quantified by strain imaging. …”
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