Integrated intra‐ and intercellular signaling knowledge for multicellular omics analysis by Dénes Türei, Alberto Valdeolivas, Lejla Gul, Nicolàs Palacio‐Escat, Michal Klein, Olga Ivanova, Márton Ölbei, Attila Gábor, Fabian Theis, Dezső Módos, Tamás Korcsmáros, Julio Saez‐Rodriguez

“…To address this gap, we combined over 100 resources covering interactions and roles of proteins in inter‐ and intracellular signaling, as well as transcriptional and post‐transcriptional regulation. We added protein complex information and annotations on function, localization, and role in diseases for each protein. …”
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Neuromodulation through brain stimulation-assisted cognitive training in patients with post-chemotherapy subjective cognitive impairment (Neuromod-PCSCI) after breast cancer: study... by Ulrike Grittner, Agnes Flöel, Sein Schmidt, Friederike Thams, Daria Antonenko, Eva-Lotta Brakemeier, Merle Rocke, Elena Knochenhauer, Anna Elisabeth Fromm, Nora Jansen, Samaneh Aziziaram, Antje Vogelgesang

“…In an exploratory approach, structural and functional MRI will be acquired before the intervention and at post-intervention to identify possible neural predictors for successful intervention.Ethics and dissemination Ethical approval was granted by the ethics committee of the University Medicine Greifswald (BB236/20). …”
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Treating nightmares in post-traumatic stress disorder with the α-adrenergic agents clonidine and doxazosin: protocol for a phase II randomised, double-blind, placebo-controlled par... by Christian Schmahl, Jürgen Gallinat, Andreas J Fallgatter, Christian Otte, Stefan Roepke, Robert Roehle, Nikola Schoofs, Kathlen Priebe, Felix Wuelfing, Tolou Maslahati, Katharina Stieglbauer, Sarah Biedermann, Ingo Schaefer, Thomas Ethofer, Bernd Hanewald, Christoph Mulert, Stefanie Koglin

“…Introduction Intrusive nightmares are a hallmark symptom of post-traumatic stress disorder (PTSD), contributing significantly to psychiatric comorbidities, impaired physical health and diminished social functioning. …”
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Automated quantitative analysis of coat and skin coloration in laboratory animals by V. A. Prikhodko, U. V. Nogaeva, D. Yu. Ivkin, S. V. Okovityi

“…Colorimetric image analysis was performed by hierarchical k-means color clustering in RGB space and cluster area calculation using the recolorize v0.2.0 function package for R v4.2.3 with RStudio v2025.05.0.Results and discussion. …”
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Analysis and correcting pronunciation disorders based on artificial intelligence approach by Nataliia Melnykova, Bohdan Pavlyk, Oleh Basystiuk, Stepan Skopivskyi

“…Tasks include reviewing existing research, selecting appropriate machine learning methods, generating relevant training data, and implementing a software architecture tailored to analyze and correct pronunciation defects in this specific population. The analysis of machine learning methods led to the selection of two experimental models: a Convolutional Neural Network (CNN) utilizing mel-spectrograms for image-based sound representation and a Long Short-Term Memory (LSTM) network combined with mel-frequency cepstral coefficients, aiming to explore the effectiveness of sequential data processing in the context of pronunciation disorder classification in post-traumatic military patients. …”
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ANALYSIS OF APOPTOSIS FACTORS IN PATIENTS WITH PREINVASIVE AND INVASIVE CERVICAL CANCER by P. I. Kovchur, E. V. Bachidze, O. V. Kurmyshkina, T. O. Volkova

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In-depth analysis of the safety of CAR-T cell therapy for solid tumors by Jiayi Dong, Jiayi Dong, Jiayi Dong, Jiayi Dong, Jiexiong Wu, Ye Jin, Ye Jin, Ye Jin, Ye Jin, Ye Jin, Zhu Zheng, Zhu Zheng, Zhu Zheng, Zhu Zheng, Zhu Zheng, Ting Su, Ting Su, Ting Su, Ting Su, Ting Su, Lijuan Shao, Lijuan Shao, Lijuan Shao, Lijuan Shao, Lijuan Shao, Jiaxin Bei, Jiaxin Bei, Jiaxin Bei, Jiaxin Bei, Size Chen, Size Chen, Size Chen, Size Chen, Size Chen

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Ser/Thr phosphorylation of Mycobacterium tuberculosis type II RelK toxin by PknK destabilizes TA interaction and interferes with toxin neutralization by Shafinaz Rahman Sarah, Abhishek Garg, Sadiyah Afroz, Shaleen Korch, Arjun Ray, Amita Gupta, Vandana Malhotra

“…We propose a model where the TA module is regulated post-translationally, specifically via Ser/Thr phosphorylation disrupting the interaction between the toxin and antitoxin proteins as a mechanism to regulate TA function.…”
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Improving serum redox balance, inflammatory status, physical function, and cognitive ability through dual-task resistance training and detraining in nursing home residents by Erivaldo Machado Araújo, Hélio José Coelho-Júnior, Caio Victor Sousa, Thiago dos Santos Rosa, Ivo Vieira Sousa Neto, Emanuele Marzetti, Octávio Luiz Franco, Samuel da Silva Aguiar

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In Vivo distribution dynamics of Gold Nanoparticles: A quantitative analysis by Angélica Barbezan, Wilmmer Alexander Rosero, Luis Fernando Almeida, Maria Eduarda Rigo, Fabio Fernando Silva, Maria Elisa Rostelato

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Analysis of disease resistance of ZmERS4 -overexpressing rice. by Wanyuan Huang, Jun Ning, Bo Su, Wenjie Liu, Ting Ding

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Effect of a Four-week Core Stability Training Program on the Kinetic Parameters in Athletes With Functional Ankle Instability During Single-leg Drop Landing by Narges Pirmohammadi, Elham Shirzad, Hooman Minounejad

“…The kinetic variables (maximum vertical Ground-Reaction Force [GRF], maximum shear GRF, and time to peak vertical GRF) were measured with force plate at the frequency of 400 Hz, in the pre-test and post-test. The obtained data were compared using Analysis of Covariance (ANCOVA) and multivariate analysis of covariance MANCOVA in SPSS V. 18. …”
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Analysis of key components in the rehabilitation diagnosis of acute stroke patients by A. A. Shmonin, M. N. Mal’ceva, A. Oshchepkov, A. V. Starceva, A. R. Zashcherinskaya, M. S. Prosvirnina, P. V. Lebedev, D. D. Glistenkova, E. v. Mel’nikova

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Which Tests Predict 6-Month Isokinetic Quadriceps Strength After ACL Reconstruction? An Examination of Isometric Quadriceps Strength and Functional Tests at 3 Months by Nicholas Giampetruzzi, Adam P Weaver, Dylan P Roman, Joshua A Cleland, Brandon M Ness

“… # Conclusion At three months post-ACLR, isometric strength testing appears more optimal than other functional tests in predicting isokinetic quadriceps peak torque in later stages of rehabilitation for adolescents. …”
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Zein-Gum Arabic Loaded with Dihydromyricetin: Preparation and Analysis of Nanoparticles by Dawei CHANG, Jiayi CAO, Na REN, Huxuan WANG, Yujiao SUN, Wen SHEN, Sendi SARA

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An analysis of heavy silicone oil treatment for inferior proliferative vitreoretinopathy by Maximilian Hammer, Amanda Ie, Katharina Eibenberger, Gerd Uwe Auffarth, Kanmin Xue

“…In this study, we conducted an in-depth analysis of complications associated with the use of heavy silicone oil in the management of inferior PVR. …”
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Contribution of sympathetic nervous system activation to endothelial ischemia reperfusion injury in healthy adults by Alexander J. Rosenberg, Benjamin E. Young, Alexander Fernandez, Ayrion W. Moody, Justin D. Sprick

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In-Vitro Assessment of Artificial Tooth Material Wear Behavior Using 3D Wear Analysis by Sıla Yelekçi, Ayben Şentürk, Funda Akaltan

“…Background: Artificial tooth wear impacts prosthesis durability and function; understanding material–antagonist interactions guides clinical choices. …”
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IL-35 Ameliorates Myocardial Strain in Mice with T2DM-Induced Cardiac Injury: Assessment by Layer-Specific Strain by Wang Z, Han L, Dong M, Liu Y, Hu X, Huang L, Zhang C, Guo L, Liu S, Liao L

“…In the context of layered strain analysis, the DMIL group exhibited a notable enhancement in middle and epicardial global longitudinal strain and global radial strain when compared to the DM group.Conclusion: IL-35 can enhance myocardial function in diabetic mice. …”
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Cardiorenal outcomes after herpes zoster reactivation in COVID-19 survivors from a global TriNetX study by Chien-Lin Lu, Joshua Wang, Ya-Chieh Chang, Kuo-Cheng Lu

“…Although no significant difference in overall all-cause mortality was observed across the full follow-up period, time-stratified analysis revealed a biphasic pattern: patients with HZ had lower mortality risk during the first 90 days but showed significantly higher mortality from day 91 to three years post-COVID-19 (HR: 1.33, 95% CI: 1.24–1.44). …”
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