Functional validation to explore the protective role of miR-223 in Staphylococcus aureus-induced bovine mastitis by Xueqin Liu, Siyuan Mi, Gerile Dari, Siqian Chen, Jiuzhou Song, David E. MacHugh, Ying Yu

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Intermittent fasting reduces alpha-synuclein pathology and functional decline in a mouse model of Parkinson’s disease by Éva M. Szegő, Lennart Höfs, Anna Antoniou, Elisabeth Dinter, Nadine Bernhardt, Anja Schneider, Donato A. Di Monte, Björn H. Falkenburger

“…IF, initiated four weeks post-induction of aSyn pathology, improved motor function and reduced dopaminergic neuron and axon terminal degeneration. …”
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Identification and Functional Characterization of Glycosylation of Recombinant Human Platelet-Derived Growth Factor-BB in Pichia pastoris. by Mengmeng Dai, Changming Yu, Ting Fang, Ling Fu, Jing Wang, Jun Zhang, Jun Ren, Junjie Xu, Xiaopeng Zhang, Wei Chen

“…Yeast Pichia pastoris is a widely used system for heterologous protein expression. However, post-translational modifications, especially glycosylation, usually impede pharmaceutical application of recombinant proteins because of unexpected alterations in protein structure and function. …”
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Time of onset of pre-eclampsia as a determinant of risk of cardiovascular disease and renal impairment at six weeks post partum: a cohort study in Lagos, Nigeria by Bosede Bukola Afolabi, Ochuwa Adiketu Babah, Olaniyi Araotan Kusamotu, Ifeoma Udenze, Ayodeji A Oluwole

“…The outcomes were cardiovascular disease risk markers, viz persistent hypertension, glucose intolerance and dyslipidaemia, and renal function at 6 weeks post partum in women who had pre-eclampsia.Statistical analysis Data were analysed using Stata V.16.1. …”
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SOUTH AFRICAN USERS’ FUNCTION AND EXPERIENCE WITH A MAGNETORHEOLOGICAL MICROPROCESSOR KNEE: A MIXED METHODS STUDY by Surona Visagie, Benje Theron

“…The descriptive qualitative study explored six purposively sampled participants’ experiences of the trial knee through semi-structured interviews. Inductive thematic analysis was done. FINDINGS: The time to complete the L-Test decreased on average 7.5 s between baseline (35.4 s) and post-test (27.9 s) data. …”
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Impact of remdesivir on liver function: A comparative study of diabetic and non-diabetic COVID-19 patients by Zahra Zarei, Elham Nejadsadeghi, Seyedeh Leila Dehghani, Fateme Dadgar

“…The impact of remdesivir treatment on liver function revealed significant increases in liver enzyme levels among patients with diabetes post-treatment, contrasting with stable liver function in non-diabetic patients. …”
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Oral creatine in hemodialysis patients increases physical functional capacity and muscle mass, an open label study. by Waldo Bernales-Delmon, Simón Schulz, Iván Guglielmi, Cynthia Saravia, Yasna Venegas, Jaime Joost, José Aguilar, Andrés Wulf, Paulina Bittner, María Claudia Martínez, Sandy Gómez, Catalina Chávez, Juan John, Felipe Matus, Carla Basualto-Alarcón

“…However, additional factors, such as low physical activity and impaired functionality, have also been identified as directly associated with increased mortality.…”
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Sex- and age-related morphological and functional differences in the skull of Eira barbara (Linnaeus, 1758) (Carnivora, Mustelidae) by Fernando Araujo Perini, Fernando L. Sicuro

“…Multivariate statistical analyses (principal component analysis/discriminant function analysis) confirmed these morphological trends, highlighting allometric growth patterns and functional differences in masticatory biomechanics. …”
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Individual alpha frequency tACS reduces static functional connectivity across the default mode network by Martín Carrasco-Gómez, Martín Carrasco-Gómez, Martín Carrasco-Gómez, Alejandra García-Colomo, Alejandra García-Colomo, Jesús Cabrera-Álvarez, Jesús Cabrera-Álvarez, Alberto del Cerro-León, Alberto del Cerro-León, Carlos J. Gómez-Ariza, Andrés Santos, Andrés Santos, Fernando Maestú, Fernando Maestú, Fernando Maestú

“…IntroductionResearch on the influence of transcranial alternating current stimulation over alpha functional connectivity (FC) is scarce, even when it poses as a potential treatment for various diseases. …”
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Delineation of and Conflict Coordination in Municipal Territorial Space Functional Zones: A Case Study of Xuzhou, China by Xizhao Liu, Xiaoshun Li, Panpan Li, Yiwei Geng, Jiangquan Chen, Guoheng Hu

“…By integrating land suitability evaluation, spatial simulation, and spatial overlay analysis, this paper delineates three functional zones and three types of conflicts for 2035: a farmland protection zone, an ecological protection zone, and an urban development zone, and construction–farmland conflicts, construction–ecological conflicts, and farmland–ecological conflicts. …”
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Brain Functional Connectivity Significantly Improves After Surgical Eradication of Porto-Systemic Shunting in Pediatric Patients by Gianvincenzo Sparacia, Giuseppe Parla, Roberto Miraglia, Jean de Ville de Goyet

“…A functional connectome analysis was performed before (“active PSS” condition) and after (“absent PSS”—physiological condition) the cure of PSS. …”
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Functional MRI-guided microsurgery of intracranial arteriovenous malformations: study protocol for a randomised controlled trial by Shuo Wang, Yuanli Zhao, Jun Wu, Bing Zhao, Yong Cao

“…Surgical complications and outcomes at pretreatment, post-treatment, at discharge and at 1-month, 3-month and 6-month follow-up intervals will be analysed using the modified Rankin Scale (mRS). …”
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Long-term Clinical and Functional Results of Neovascular Glaucoma Surgical Treatment with Glautex Drainage and Ahmed Valve by M. M. Bikbov, I. I. Khusnitdinov

“…There was no surgical treatment effect for 3 years in Group I in 60.8% (14/23), in group II — 33.3% (7/21) of the cases.Conclusion. The analysis of clinical and functional results of surgical treatment of patients with neovascular glaucoma in terms of 3 years follow up showed that the most lasting preservation of visual function and the hypotensive effect was achieved after implantation of the Ahmed valve — in 66.7% of the cases. …”
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Changes in brain network dynamics during functional/dissociative seizures: An exploratory pilot study on EEG microstates by Domantė Kučikienė, Johannes Jungilligens, Stefan Wolking, Yvonne Weber, Jörg Wellmer, Stoyan Popkirov

“…The pathophysiology of functional/dissociative seizures (FDS), also known as psychogenic nonepileptic seizures, remains incompletely understood. …”
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Absence of Exogenous Glucose in the Perfusate During Kidney Hypothermic Machine Perfusion Does Not Affect Mitochondrial Function by Dafni Efraimoglou, L. Annick van Furth, Albert Gerding, Barbara M. Bakker, Jan-Luuk Hillebrands, Henri G. D. Leuvenink, Leonie H. Venema

“…Hypothermic machine perfusion (HMP) has emerged as an effective method to improve graft function post-transplantation, particularly for deceased donor kidneys, prone to ischemia reperfusion injury (IRI). …”
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Affective Modulation after High-Intensity Exercise Is Associated with Prolonged Amygdalar-Insular Functional Connectivity Increase by Angelika Schmitt, Neeraj Upadhyay, Jason Anthony Martin, Sandra Rojas Vega, Heiko Klaus Strüder, Henning Boecker

“…Acute moderate exercise has been shown to induce prolonged changes in functional connectivity (FC) within affect and reward networks. …”
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Mediating effect of kinesiophobia between self-efficacy and physical activity levels in post-CABG patients: protocol for a prospective, multicentre, cross-sectional study in China by Yu Chen, Rong Wang, Yanmei Gu, Jing Jing Piao, Yunpeng Ling, Liqun Chi

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Self-reported health, neuropsychological tests and biomarkers in fully recovered COVID-19 patients vs patients with post-COVID cognitive symptoms: A pilot study. by Michael R Lawrence, Judith E Arnetz, Scott E Counts, Aiesha Ahmed, Bengt B Arnetz

“…Results of decreased neuroplastic functioning give credence to patients' reports of post-COVID changes in brain function.…”
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Functioning in patients with major depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia by Novick D, Montgomery W, Haro JM, Moneta MV, Zhu G, Yue L, Hong J, Duenas H, Brugnoli R

“…In addition, this study examined the impact of painful physical symptoms (PPS) on the effects of these treatments.Patients and methods: Data for this post hoc analysis were taken from a 6-month prospective observational study involving 1,549 patients with major depressive disorder without sexual dysfunction. …”
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HONORING WAR VETERANS AS A COMPONENT OF THE IMPLEMENTATION OF THE SOCIO-ECONOMIC FUNCTION OF THE STATE: ADMINISTRATIVE-LEGAL ASPECT by Liudmyla Sylenko, Serhii Sivkov, Denys Komarnytskyi

“…Various methods are used when studying the honouring of war veterans as an important element of the state's socio-economic function in special circumstances. These methods allow for a comprehensive consideration of the legal, social, economic and managerial aspects of this area, and include: the method of dialectical materialism; the method of abstraction; the methods of analysis and synthesis; the functional method; the method of system analysis; the synergistic method; the comparative law method; the method of interpretation and hermeneutics; the dogmatic method; and the statistical method. …”
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