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    RNA‐Binding Protein Hnrnpa1 Triggers Daughter Cardiomyocyte Formation by Promoting Cardiomyocyte Dedifferentiation and Cell Cycle Activity in a Post‐Transcriptional Manner by Chuling Li, Yijin Chen, Qiqi Chen, Haoxiang Huang, Michael Hesse, Yilin Zhou, Ming Jin, Yu Liu, Yifei Ruan, Xiang He, Guoquan Wei, Hao Zheng, Senlin Huang, Guojun Chen, Wangjun Liao, Yulin Liao, Yanmei Chen, Jianping Bin

    Published 2025-01-01
    “…Hnrnpa1 knockout inhibited cardiac regeneration and worsened cardiac function in the neonatal MI model. Nanopore RNA sequencing, RIP assay, IP‐MS, MeRIP‐qPCR, PAR‐CLIP and luciferase reporter experiments showed that Hnrnpa1 induced Mettl3 post‐transcriptional splicing to inhibit m6A‐dependent Pbx1 and E2F1 degradation, thereby increasing Runx1, Ccne1, Cdk2 and Ccnb2 expression to promote CM DACCA. …”
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  4. 964

    Epicardial Adipose Tissue and Heterogeneity Parameters Combined with Inflammatory Cells to Predict the Value of Heart Failure with Preserved Ejection Fraction Patients Post Myocard... by Yu-jiao Song, Xiao-ying Zhao, Lu-jing Wang, Ting Ning, Ming-tian Chen, Pei Liu, Si-wen Chen, Xin-xiang Zhao

    Published 2025-05-01
    “…The cohort was stratified into two groups: those without HFpEF and those who developed HFpEF.Cardiac structure, function, EAT volume, and infarct volume parameters were obtained using the CMR post-processing software CVI-42, while EAT heterogeneity parameters entropy were derived using Python software. …”
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  5. 965

    Correlation between fatigue and pulmonary involvement in the post-COVID-19 condition: a cross-sectional study 6–12 months after hospital discharge by Paulo A Lotufo, Juliana C Ferreira, Eloisa Bonfa, Anna S Levin, Rodrigo Caruso Chate, Marta Imamura, Esper G Kallas, Roger Chammas, Thais Mauad, Izabel Marcilio, Nelson Gouveia, Ricardo Nitrini, José Eduardo Krieger, Marcio Valente Yamada Sawamura, Carlos Roberto Ribeiro de Carvalho, Cristiano Gomes, Jorge Hallak, Luis Yu, Marcio Mancini, Maria Elizabeth Rossi, Thiago Avelino-Silva, Edivaldo M Utiyama, Aluisio C Segurado, Beatriz Perondi, Anna Miethke-Morais, Amanda C Montal, Leila Harima, Solange R G Fusco, Marjorie F Silva, Marcelo C Rocha, Carolina Carmo, Clarice Tanaka, Julio F M Marchini, Thaís Guimarães, Ester Sabino, Tarcisio E P Barros-Filho, Celina Almeida Lamas, João Marcos Salge, Cesar Higa Nomura, Adriana L Araújo, Bruno F Guedes, Carolina S Lázari, Cassiano C Antonio, Claudia C Leite, Emmanuel A Burdmann, Euripedes C Miguel, Fabio R Pinna, Geraldo F Busatto, Giovanni G Cerri, Heraldo P Souza, Izabel C Rios, Larissa S Oliveira, Linamara R Batisttella, Marcello M C Magri, Maura S Oliveira, Orestes V Forlenza, Ricardo F Bento, Rodolfo F Damiano, Rossana P Francisco, Wilson J Filho, Mateus Satoru Kajiwara, Luis Augusto Visani de Luna, Thais Suemi Yokoyama, Pedro Rizzi de Oliveira, Maria Amelia de Jesus, Vilson C Junior

    Published 2025-07-01
    “…Introduction Post-COVID-19 conditions (PCC) may include pulmonary sequelae, fatigue and other symptoms, but its mechanisms are not fully elucidated.Objective This study investigated the correlation between fatigue and the presence of pulmonary abnormalities in PCC patients with respiratory involvement 6–12 months after hospitalisation.Design Cross-sectional study.Setting A tertiary hospital in Brazil.Participants 315 patients, aged ≥18 years, were considered eligible based on SARS-CoV-2 infection confirmed by reverse transcription-PCR.Methods Pulmonary function tests (PFT), cardiopulmonary exercise tests (CPET), chest CT and hand grip were performed. …”
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  6. 966

    Application of Post-Occupancy Evaluation in the Design of Collegiatae Educational Space: (Case study: Faculty of Arts and Architecture, Islamic Azad University-Tehran South Branch) by Reza Naghdbishi, Zeinab Gohari

    Published 2024-02-01
    “…The study emphasizes the importance of post-occupancy evaluation and user participation as a means to address the limitations of building usage. …”
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    Prognostic significance of NT-proBNP and sST2 biomarkers in patients with post-myocardial infarction heart failure after a coronavirus infection by N. M. Kalashnikova, D. N. Zaitsev, A. V. Govorin, M. V. Chistyakova, B. T. Balzhitov

    Published 2023-07-01
    “…To determine the prognostic significance of N-terminal pro-brain natriuretic peptide (NT-proBNP) and soluble ST2 (sST2) in patients with post-myocardial infarction heart failure after a coronavirus disease 2019 (COVID-19)Material and methods. …”
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  9. 969

    Study protocol for the Outcomes Post-Treatment: Impact on Motor Impairment of Sleep Efficiency in Spinal Cord Injury (OPTIMISE SCI) – a randomised controlled trial by Julio C Furlan, Sandra Walsh, Mark Boulos, Christie Yao, Martha McKay

    Published 2025-06-01
    “…The OPTIMISE SCI (Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI) is an ongoing phase 3 clinical trial focused on the effects of the early use of continuous positive airway pressure (CPAP) therapy to treat individuals with moderate-to-severe SRBDs in the acute/subacute stage after SCI.Methods and analysis A total of 44 participants with SCI who are newly diagnosed with moderate-to-severe SRBD are randomised into early CPAP therapy (initiated within the first 8 weeks postinjury) versus delayed CPAP therapy (initiated at 6 months postinjury). …”
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    ‘...the opium of the people’? Religiosity in socialist new towns by Márton Berki, Brigitta Sivadó

    Published 2018-09-01
    “…Although an undoubtedly growing body of scholarly work deals with the economic, political and institutional transformation of post-socialist cities, the no less profound cultural changes former socialist cities have undergone since the beginning of the transition still remain relatively under-theorised. …”
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    Evolutionary analysis of the DHHCs in Saccharinae by Hao Wen, Xinyu Liu, Xueting Zhao, Tingting Zhao, Cuilian Feng, Hailong Chang, Jungang Wang, Jishan Lin

    Published 2025-01-01
    “…Abstract The DHHC domain genes are crucial for protein lipid modification, a key post-translational modification influencing membrane targeting, subcellular trafficking, and protein function. …”
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    Randomized Control Trial Comparing Effects of Tourniquets on Neurology and Functional Outcomes after Total Knee Arthoplasty by Gur-Aziz Singh Sidhu, Saphalya Pattnaik, Mothana Gawad, Rafia Ghani, Harjot Kaur, Neil Ashwood

    Published 2025-08-01
    “…The literature reveals a divided opinion on whether TKA should be performed with or without a tourniquet, with conflicting results on post-operative pain, blood loss, and functional outcomes.. …”
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    Predicting acupuncture efficacy for neck pain based on functional connectivity features: a machine learning study by Zhen Gao, Mengjie Cui, Cheng Xu, Haijun Wang, Yanlin Zhang, Laixi Ji

    Published 2025-12-01
    “…Longitudinal analysis showed 6 predictive features altered post-treatment in responders versus 44 in non-responders. …”
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    Effects of sexual counseling and education based on self-efficacy theory on the sexual function of women with breast cancer by Azadeh Jamshidi, Farzaneh Noroozi, Razieh Bagherzadeh, Tayebeh Gharibi

    Published 2025-01-01
    “…The current study aimed to examine the impact of sexual counseling and education based on self-efficacy theory on the sexual function of women with breast cancer. Method The trial was a randomized controlled trial with a parallel design, including a pre-test, post-test, and one-month follow-up. …”
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    Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study by Owen Griffith, Xiaoxiao Bai, Alexa E. Walter, Michael Gay, Jon Kelly, Wayne Sebastianelli, Linda Papa, Semyon Slobounov

    Published 2025-01-01
    “…During group analysis, first, voxel-wise paired sample t-tests identified significant changes in connectivity from pre- to post-season, by player, and previous concussion history. …”
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