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RNA‐Binding Protein Hnrnpa1 Triggers Daughter Cardiomyocyte Formation by Promoting Cardiomyocyte Dedifferentiation and Cell Cycle Activity in a Post‐Transcriptional Manner
Published 2025-01-01“…Hnrnpa1 knockout inhibited cardiac regeneration and worsened cardiac function in the neonatal MI model. Nanopore RNA sequencing, RIP assay, IP‐MS, MeRIP‐qPCR, PAR‐CLIP and luciferase reporter experiments showed that Hnrnpa1 induced Mettl3 post‐transcriptional splicing to inhibit m6A‐dependent Pbx1 and E2F1 degradation, thereby increasing Runx1, Ccne1, Cdk2 and Ccnb2 expression to promote CM DACCA. …”
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964
Epicardial Adipose Tissue and Heterogeneity Parameters Combined with Inflammatory Cells to Predict the Value of Heart Failure with Preserved Ejection Fraction Patients Post Myocard...
Published 2025-05-01“…The cohort was stratified into two groups: those without HFpEF and those who developed HFpEF.Cardiac structure, function, EAT volume, and infarct volume parameters were obtained using the CMR post-processing software CVI-42, while EAT heterogeneity parameters entropy were derived using Python software. …”
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Correlation between fatigue and pulmonary involvement in the post-COVID-19 condition: a cross-sectional study 6–12 months after hospital discharge
Published 2025-07-01“…Introduction Post-COVID-19 conditions (PCC) may include pulmonary sequelae, fatigue and other symptoms, but its mechanisms are not fully elucidated.Objective This study investigated the correlation between fatigue and the presence of pulmonary abnormalities in PCC patients with respiratory involvement 6–12 months after hospitalisation.Design Cross-sectional study.Setting A tertiary hospital in Brazil.Participants 315 patients, aged ≥18 years, were considered eligible based on SARS-CoV-2 infection confirmed by reverse transcription-PCR.Methods Pulmonary function tests (PFT), cardiopulmonary exercise tests (CPET), chest CT and hand grip were performed. …”
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Application of Post-Occupancy Evaluation in the Design of Collegiatae Educational Space: (Case study: Faculty of Arts and Architecture, Islamic Azad University-Tehran South Branch)
Published 2024-02-01“…The study emphasizes the importance of post-occupancy evaluation and user participation as a means to address the limitations of building usage. …”
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Prognostic significance of NT-proBNP and sST2 biomarkers in patients with post-myocardial infarction heart failure after a coronavirus infection
Published 2023-07-01“…To determine the prognostic significance of N-terminal pro-brain natriuretic peptide (NT-proBNP) and soluble ST2 (sST2) in patients with post-myocardial infarction heart failure after a coronavirus disease 2019 (COVID-19)Material and methods. …”
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Study protocol for the Outcomes Post-Treatment: Impact on Motor Impairment of Sleep Efficiency in Spinal Cord Injury (OPTIMISE SCI) – a randomised controlled trial
Published 2025-06-01“…The OPTIMISE SCI (Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI) is an ongoing phase 3 clinical trial focused on the effects of the early use of continuous positive airway pressure (CPAP) therapy to treat individuals with moderate-to-severe SRBDs in the acute/subacute stage after SCI.Methods and analysis A total of 44 participants with SCI who are newly diagnosed with moderate-to-severe SRBD are randomised into early CPAP therapy (initiated within the first 8 weeks postinjury) versus delayed CPAP therapy (initiated at 6 months postinjury). …”
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Early cardiac events after haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide. subanalysis exploring cardiac toxicity conducted on behalf of GE...
Published 2025-05-01“…ECEs, defined as any new cardiac event within 100 days post-transplant, were analyzed using cumulative incidence functions considering death and relapse as competing risks. …”
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Pioneering the Security of EHRs Using an Immersive Blockchain Conceptual Framework
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972
‘...the opium of the people’? Religiosity in socialist new towns
Published 2018-09-01“…Although an undoubtedly growing body of scholarly work deals with the economic, political and institutional transformation of post-socialist cities, the no less profound cultural changes former socialist cities have undergone since the beginning of the transition still remain relatively under-theorised. …”
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Visual Impairment in Stroke Patients: a Two-Part Review. Part II — Rehabilitation Methods
Published 2024-12-01Get full text
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Risk factors for the formation of gastroenterological pathology after infectious hemocolitis in children
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Evolutionary analysis of the DHHCs in Saccharinae
Published 2025-01-01“…Abstract The DHHC domain genes are crucial for protein lipid modification, a key post-translational modification influencing membrane targeting, subcellular trafficking, and protein function. …”
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Randomized Control Trial Comparing Effects of Tourniquets on Neurology and Functional Outcomes after Total Knee Arthoplasty
Published 2025-08-01“…The literature reveals a divided opinion on whether TKA should be performed with or without a tourniquet, with conflicting results on post-operative pain, blood loss, and functional outcomes.. …”
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Predicting acupuncture efficacy for neck pain based on functional connectivity features: a machine learning study
Published 2025-12-01“…Longitudinal analysis showed 6 predictive features altered post-treatment in responders versus 44 in non-responders. …”
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Effects of sexual counseling and education based on self-efficacy theory on the sexual function of women with breast cancer
Published 2025-01-01“…The current study aimed to examine the impact of sexual counseling and education based on self-efficacy theory on the sexual function of women with breast cancer. Method The trial was a randomized controlled trial with a parallel design, including a pre-test, post-test, and one-month follow-up. …”
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Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study
Published 2025-01-01“…During group analysis, first, voxel-wise paired sample t-tests identified significant changes in connectivity from pre- to post-season, by player, and previous concussion history. …”
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