Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model by Shunan Wang, Ming Shen, Bo Pang, Bo Zhou, Yuan Yuan, Mei Lu, Xiangling Deng, Min Yang, Shufang Liu, Qiong Wang, Mei Xue, Qisheng Xia, Zhixin Zhang

“…The knockout mice exhibit hyperphenylalaninemia, impaired cognitive function, and decreased monoamine neurotransmitters. …”
Get full text

High-altitude hypoxia exacerbates chemotherapy-induced myelosuppression by lowering serum G-CSF/GM-CSF and regulating apoptosis and proliferation by Jing Shi, Fuxing Zhao, Tianlei Qiu, Dengfeng Ren, Zitao Li, Junli Ma, Jiuda Zhao

“…High-altitude hypoxia also significantly reduced serum levels of granulocyte colony-stimulating factor (G-CSF) and granulocyte–macrophage colony-stimulating factor (GM-CSF). Transcriptomic analysis of BMNCs demonstrated that high-altitude hypoxia might modulate the hematopoietic function in CTX-induced myelosuppression mice through pathways related to hematopoiesis, such as porphyrin metabolism, hematopoietic cell lineage, ECM-receptor interaction, and PI3K-Akt signaling pathway. …”
Get full text

Arterial stiffness and endothelial function in the long-term period after a coronavirus disease 2019 by S. A. Bondar, O. P. Rotar, E. V. Moguchaya, M. А. Boyarinova, E. P. Kolesova, E. Yu. Vasilyeva, A. A. Mikhailova, T. L. Karonova, A. O. Konradi

“…To assess endothelial function and arterial stiffness over time in patients after hospitalization with coronavirus disease 2019 (COVID-19) and compare them with a control group.Material and methods. …”
Get full text

PREDICTION AND PREVENTION OF LIVER FAILURE AFTER MAJOR LIVER PRIMARY AND METASTATIC TUMORS RESECTION by A. D. Kaprin, D. V. Sidorov, N. A. Rubtsova, A. V. Leontyev, M. V. Lozhkin, L. O. Petrov, N. A. Grishin, T. N. Lazutina, I. V. Pylova, A. G. Isaeva

“…Improvement of results of treatment in patients with primary and metastatic liver cancer by decreasing the risk of post-resection liver failure on the basis of the evaluation of the functional reserves of the liver.Materials and Methods. …”
Get full text

A specifically designed multi-biotic reduces uremic toxin generation and improves kidney function by Alice Beau, Jane Natividad, Berengère Benoit, Philippe Delerive, Stéphane Duboux, Yuan Feng, Marie Jammes, Cecile Barnel, Giuseppina Sequino, Claudie Pinteur, Griet Glorieux, Denis Fouque, Hubert Vidal, Laetitia Koppe

“…Metagenomic analysis revealed reduced microbial genes for tryptophan/tyrosine degradation. …”
Get full text

The Functional Network of PrkC and Its Interaction Proteins in <i>Bacillus subtilis</i> Spores by Kangyi Mu, Tianlin Cui, Zequn Zhang, Yicong Shi, Chen Fang, Li Dong, Xiaosong Hu

“…Additionally, proteins are categorized into six groups by function based on events that may be associated with post-germination triggered by peptidoglycan-induced activation of the PrkC signaling pathway, including “stimulate translation initiation” and “ATP synthesis and energy metabolism”. …”
Get full text

Acromegaly in Speckle Tracking Echocardiography—A New Cardiac Hypertrophy Phenotype? Case Report and Review by Alexander Suchodolski, Monika Wójcik-Giertuga, Beata Kos-Kudła, Mariola Szulik

“…Conclusions: While the available literature on STE in acromegaly is limited, our analysis suggests potential applications in differentiating hypertrophy aetiologies and monitoring cardiac function post-treatment. …”
Get full text

Temporal evolution and factors influencing visual function and RNFL thickness in ethambutol-associated optic neuropathy by Taimin Guo, Yue Fu, Xiaoyu Xu, Xiaoning Liu, Yurong Zhang, Hui Yang

“…Macular ganglion cell-inner plexiform layer (mGCIPL) thickness showed a decreasing trend (73.20 ± 4.76 μm to 55.33 ± 4.16 μm) from 1 month post-onset. Multivariate analysis revealed that disease course was the primary factor influencing VF recovery (β = − 0.31, p = 0.001), while peripapillary retinal nerve fiber layer thinning was associated with gender, ethambutol dosage, and disease duration. …”
Get full text

The Effect of a Combined Scapula and Shoulder Exercise Program with Kinesio Tape on Pain, Shoulder Proprioception, and Upper Limb Function in Swimmers with Shoulder Impingement Syn... by Seyedeh Farzaneh Sadri, Mohammad Saleki

“…After the training program concluded, post-tests were administered. To compare the research variables between the experimental and control groups, analysis of covariance (ANCOVA) and paired t-tests were used. …”
Get full text

Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast by Ronish Gupta, Bart Kus, Christopher Fladd, James Wasmuth, Raffi Tonikian, Sachdev Sidhu, Nevan J Krogan, John Parkinson, Daniela Rotin

Get full text

Long-term impact on cardiopulmonary function and quality of life among patients recovered from SARS-CoV-2 infection in a 6-month follow-up period in Lima, Peru: FUNCTION cohort stu... by Carlos Seas, Larissa Otero, Eduardo Gotuzzo, Fernando Mejia, Rodrigo Cachay, Takashi Watanabe-Tejada, Katiuska Cuno, Marcela Gil-Zacarias, Carolina Coombes, Isabel Ballena, Felix Medina, Oscar Gayoso

“…Longitudinal assessments and reversibility of changes across the spectrum of disease severity are required to understand the long-term impact of COVID-19.Methods and analysis A prospective cohort study aims to assess the impact of SARS-CoV-2 infection on cardiopulmonary function and quality of life after the acute phase of the disease over a 6-month follow-up period. …”
Get full text

Intermediary Virtual Dialogue in VKontakte Social Network vs. Immediate Live Dialogue: Functions and Structure by Nikolay D. Golev, Nadezhda N. Shpilnaya

“…They were obtained from posts and comments in the public Anonymous; posts and comments on the public page Vesti; posts and comments on personal home pages of native Russian speakers. …”

Where lol Is: Function and Position of lol Used as a Discourse Marker in YouTube Comments by Célia Schneebeli

“…Using the tools of discourse analysis and pragmatics, the study examines the functions of lol on two levels: the level of discourse organization and the level of social interaction.…”
Get full text

Prevalence and characteristics of newly diagnosed heart failure in patients with shortness of breath after coronavirus infection by O. V. Masalkina, N. A. Koziolova, N. M. Syuzeva

Get full text

Predictors of response and enteral autonomy in children with short bowel syndrome treated with teduglutide: a real-life multicentre cohort studyResearch in context by Lorenzo Norsa, Arianna Ghirardi, Esther Ramos Boluda, Anat Guz-Mark, Iva Hojsak, Johannes Hilberath, Ilse Juia Broekaert, Rocío González Sacristán, Antonella Lezo, Paula Guerra, Pierre Poinsot, Cecile Lambe, Lorenzo D'Antiga

Get full text

Differential Gene and Protein Expressions Responsible for Vasomotor Signaling Provide Mechanistic Bases for the Opposite Flow-Induced Responses of Pre- and Post-Circle of Willis Ar... by Zoltan Nemeth, Krisztian Eros, Gyongyi Munkacsy, Akos Koller

Get full text

Physiotherapy After Anterior Cruciate Ligament Reconstruction – a Literature Review by Karolina Rutkowska-Kogut, Aleksandra Truszczyńska-Baszak, Zuzanna Wrzesień

Get full text

Gestión de riesgos en la realización de pruebas de función pulmonar pospandemia by Luis Puente Maestu, Juana M. Martínez Llorens, José Luis Valera Felices, Yolanda Torralba García, Marian Gimeno Peribáñez, Eusebi Chiner, Roberto Cabestre, Juan Rodríguez Hermosa, Raúl Godoy Mayoral, Celeste Marcos, Ana Balaña Corberó, Carlos Almonacid

“…Abstract: This document is a detailed proposal addressing the management of spirometry and other pulmonary function tests in the post-COVID-19 pandemic context in Spain. …”
Get full text

丁苯酞序贯治疗急性缺血性卒中有效性和安全性的meta分析Meta-Analysis of the Efficacy and Safety of Butylphthalide Sequential Treatment in Acute Ischemic Stroke by 胡燕琴，王铄，赵陶丽，郭东兴，李申，金振波 (HU Yanqin, WANG Shuo, ZHAO Taoli, GUO Dongxing, LI Shen, JIN Zhenbo)

“…Baseline information, treatment details, and efficacy indicators [rate of good prognosis (mRS score 0-2) at 90 days, post-treatment neurological status (assessed by NIHSS score), post-treatment functional status (assessed by mRS score), and post-treatment activity of daily living (ADL) score], and safety indicators (adverse events and serious adverse events) were extracted. …”
Get full text

Post-Liver Transplant Kidney Dysfunction: Incidence of Acute Kidney Injury and Chronic Kidney Disease and Risk Factors Related to Chronic Kidney Disease Development by Ana Flavia Moura, José A. Moura-Neto, Beatriz de Melo Ribeiro, Paula Ribeiro Oliveira, Arthur Guimarães de Freitas, Alessandra Lima Costa, Daniela Moura-Landim, Liana Codes, Paulo Lisboa Bittencourt, Constança Margarida Sampaio Cruz

“…This study aimed to determine the incidence of AKI and CKD post-LT and to identify risk factors associated with CKD development. …”
Get full text