Frequency-dependent changes in the amplitude of low-frequency fluctuations in post stroke apathy: a resting-state fMRI study by Ying Liu, Ying Liu, Yi-Kuang Hsien, Yi-Kuang Hsien, Wenlong Su, Wenlong Su, Zhiqing Tang, Zhiqing Tang, Hui Li, Junzi Long, Junzi Long, Xingxing Liao, Xingxing Liao, Hao Zhang, Hao Zhang, Hao Zhang

“…Understanding the pathophysiological mechanisms of post stroke apathy (PSA) is crucial for developing targeted rehabilitation strategies.MethodsIn this study, we recruited a total of 18 PSA patients, 18 post-stroke non-apathy (NPSA) patients, and 18 healthy controls (HCs). …”
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Novel post-translational modification learning signature reveals B4GALT2 as an immune exclusion regulator in lung adenocarcinoma by Ge Zhang, Zhenfa Zhang, Lianmin Zhang, Guangyao Zhou, Pengpeng Zhang, Dingli Wang, Shuai Jiang

“…Background Lung adenocarcinoma (LUAD) presents significant challenges in prognosis and treatment efficacy evaluation. While post-translational modifications are known to influence tumor progression, their prognostic value in LUAD remains largely unexplored.Methods We developed a post-translational modification learning signature (PTMLS) using machine learning techniques, analyzing data from 1231 LUAD patients across seven global cohorts. …”
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MAST Kinases’ Function and Regulation: Insights from Structural Modeling and Disease Mutations by Michael C. Lemke, Nithin R. Avala, Michael T. Rader, Stefan R. Hargett, Daniel S. Lank, Brandon D. Seltzer, Thurl E. Harris

“…<b>Methods</b>: We investigated MAST-lineage kinases using database and sequence analysis. We also estimate the functional consequences of disease point mutations on protein stability by integrating predictive algorithms and AlphaFold. …”
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The strong correlation between visual function improvement and retinal microcirculation enhancement in glaucoma by Ting Wang, Ting Wang, Qiying Ling, Boyu Shen, Xu Jia

“…We measured peripapillary and macular VD, retinal nerve fiber layer (RNFL) thickness, foveal avascular zone (FAZ), and visual field (VF) parameters before treatment, and at 1 week, 1 month, 3 months, and 6 months post-treatment. The data were analyzed using ANOVA and Pearson correlation analysis.ResultsA total of 20 patients were included. …”
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Liver Function Test and Diabetes Mellitus: Correlation from a Laboratory Perspective by Aditya Chilay, Neha Mehra, Moumita Misra, Raj Jatale, Shibani Ramchandran

“…The patients included those who had tested for liver function tests (LFTs) [including SGPT, SGOT, ALP, GGTP, lactate dehydrogenase (LDH)], blood sugar (fasting and post lunch), and HbA1c. …”
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Right Ventricular Function Score by Echocardiography for Predicting Outcomes After Heart Transplantation by Wei Sun, Yuji Xie, Ye Zhu, Yun Yang, Xin Zhang, Nianguo Dong, Guohua Wang, Yuman Li, Jing Wang, Qing Lv, Mingxing Xie, Li Zhang

“…RV systolic function was evaluated by echocardiography. A multivariate Cox regression analysis was performed to identify the independent predictors of RV function for adverse clinical events. …”
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Designing sustainable antioxidant and anti-inflammatory ingredients from seaweeds for functional gummies by Bruno Toribio de Lima Xavier, Marcelo Franchin, Nima Mohammadi, Carolina Girotto Pressete, Lusânia Maria Greggi Antunes, Yandong Xu, Kai Wang, Jason Bennett, Daniel Granato

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TET1 displays catalytic and non-catalytic functions in the adult mouse cortex by Yee Hoon Foong, Blake Caldwell, Joanne L. Thorvaldsen, Christopher Krapp, Clementina A. Mesaros, Wanding Zhou, Rahul M. Kohli, Marisa S. Bartolomei

“…Using DNA methylation array, we uncover that Tet1 HxD and KO mutations perturb the methylation status of distinct subsets of CpG sites. Gene ontology (GO) analysis on specific differential 5hmC regions indicates that TET1’s catalytic activity is linked to neuronal-specific functions. …”
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Acute Effect of a Single Functional Neurology Intervention on Muscular Trigger Point by Jorge Rey-Mota, Guillermo Escribano-Colmena, Athanasios A. Dalamitros, Rodrigo Yáñez-Sepúlveda, David Martín-Caro Álvarez, Eduardo Navarro Jimenez, Vicente Javier Clemente-Suárez

“…Methods: A randomized controlled trial (RCT) was conducted with 63 participants randomly assigned to an experimental (receiving functional neurology treatment) or control group. Pre- and post-treatment assessments were conducted, and both intra- and inter-group comparisons were performed using algometry to measure the PPT and infrared thermography to analyze peripheral vascular response. …”
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Alterations in functional and structural connectivity in the 6-OHDA-induced Parkinsonian rat model by Shuyi Zhu, Shuyi Zhu, Maurizio Bergamino, Alberto Fuentes, Ivette M. Sandoval, David J. Marmion, Christopher Bishop, Fredric P. Manfredsson, Ashley M. Stokes

“…Structurally, we observed reduced connectivity between the subcoeruleum and piriform cortex in the 6-OHDA model, which may reflect axonal degeneration, and increased connectivity between the ventral striatum and primary somatosensory cortex, which likely reflects compensatory changes to support motor-sensory integration. Diffusion MRI analysis further revealed changes in the white matter tracts connecting these regions, supporting these findings and highlighting adaptive responses to neurodegeneration in PD.DiscussionThese findings demonstrate the utility of combining functional and structural connectivity analyses to capture PD-related network disruptions. …”
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Impact of COVID-19 Vaccination on Cardiac Function and Survival in Maintenance Hemodialysis Patients by Xiao Tu, Tingfei He, Bing Xu, Jiazhen Yin, Fangyu Yi, Ye Li, Jinchi Gao, Peng Bi, Wanyue Xu, Rihong Hu, Lidan Hu, Yayu Li

“…We compared the pre- and post-infection changes in heart function (echocardiographic parameters) and BNP levels between the two groups and assessed their association with the survival rates. …”
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Subjective experience, psychosocial functioning and different psychomotor clusters in catatonia: How are they connected? by Geva A. Brandt, Stefan Fritze, Dilsa Cemre Akkoc Altinok, Sebastian Volkmer, Jacqueline Kukovic, Jonas Daub, Katharina M. Kubera, Georg Northoff, Andreas Meyer-Lindenberg, Dusan Hirjak

“…Group differences were analyzed using MANCOVA and post-hoc ANOVA. Finally, linear discriminant analysis (LDA) was used to examine the classification value of the respective rating scales and different surrogate parameters of ICD-11-related psychomotor activity. …”
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Association of inflammation cytokines with cognitive function in first-episode major depressive disorder by Yan Qing Xi, Yan Qing Xi, Yan Qing Xi, Zong Qi Wang, Zong Qi Wang, Zong Qi Wang, Guo Juan Li, Guo Juan Li, Guo Juan Li, Zhuo Qun Hao, Zhuo Qun Hao, Zhuo Qun Hao, Jia Hui Nie, Jin Xiang Li, Yu Ting Tan, Xiao Dong Hu, Xiao Dong Hu, Gen Wei Wang, Sha Liu, Sha Liu, Yan Fang Wang, Yan Fang Wang, Yan Fang Wang

“…Multiple regression analysis indicated an association between TNF-α levels and attention scores in MDD patients at baseline.ConclusionsOur study concludes that TNF-α and BDNF correlate with cognitive function in MDD at baseline, and furthermore, TNF-α could potentially serve as an objective biomarker to support the assessment of attentional function at baseline.…”
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Current implications of EEG and fNIRS as functional neuroimaging techniques for motor recovery after stroke by Sun Xiaolong, Dai Chunqiu, Wu Xiangbo, Han Tao, Li Qiaozhen, Lu Yixing, Liu Xinyu, Yuan Hua

“…Quantitative electroencephalography (qEEG) parameters, including the power ratio index, brain symmetry index, and phase synchrony index, have emerged as potential prognostic markers for overall motor recovery post-stroke. Current evidence suggests a correlation between qEEG parameters and functional motor outcomes in stroke recovery. …”
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Impact of β-defensin 103 (DEFB103) copy number variation on bull sperm parameters and post-insemination uterine gene expression. by Ozge Sidekli, Edward J Hollox, Sean Fair, Kieran G Meade

“…Transcriptomic analysis on uterine tissue harvested 12 h post-insemination showed differential expression of 58 genes (FDR < 0.1) involved in sperm migration, immune signalling and chemotaxis. …”
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Tanshinone I promotes angiogenesis and improves ventricular remodeling post-myocardial infarction via ALDH2 signaling-mediated ferroptosis inhibition by Feng Zhang, Lei Li, Qian Liu, Wen-Long Wang, Zhi-Xin Wang, Rong-Qiang Song, Jian Sun, Yi-Yi Zhang, Xin-Chen Ren, Dong Wang, Yu-Ting Wu, Yu-Ting Wu

“…Thus, we investigated how EC ferroptosis mediates post-MI angiogenesis and Tan I's role in this process.MethodsIn vivo experiments: A mouse model of MI was established to evaluate cardiac function, myocardial injury, collagen deposition, and EC ferroptosis. …”
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Oestrogen suppresses the adipogenesis of fibro/adipogenic progenitors through reactivating the METTL3–ESR1‐mediated loop in post‐menopausal females by Hao Zhou, Shujing Feng, Jinkui Cai, Xiexiang Shao, Siyuan Zhu, Han Zhou, Yongmin Cao, Ru Wang, Xingzuan Lin, Jianhua Wang

“…The effects of estrogen supplementation on muscular fatty infiltration and locomotor function in OVX mice were evaluated by immunofluorescent staining and functional analysis. …”
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Deep Temporal Clustering of Pathological Gait Patterns in Post-Stroke Patients Using Joint Angle Trajectories: A Cross-Sectional Study by Gyeongmin Kim, Hyungtai Kim, Yun-Hee Kim, Seung-Jong Kim, Mun-Taek Choi

“…Rehabilitation of gait function in post-stroke hemiplegic patients is critical for improving mobility and quality of life, requiring a comprehensive understanding of individual gait patterns. …”
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Nicotinamide mononucleotide biosynthesis and the F-actin cytoskeleton regulate spindle assembly and oocyte maturation quality in post-ovulatory aged porcine oocytes by Hyo-Jin Park, Seul-Gi Yang, Ji-Hyun Shin, Seung-Bin Yoon, Ji-Su Kim, Deog-Bon Koo

“…Abstract Background Post-ovulatory aging (POA) is associated with reduced fertilization rates and poor embryo quality both in vivo and in vitro. …”
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Changes in neurocognitive function after acute high-intensity exercise: decreasing the biomechanical risk factors of ACL injury by Mika Konishi, Satoshi Shibata, Masahiro Takemura

“…Fourteen collegiate female athletes performed a bicycle ergometer HIE exercise at 80% of their heart rate reserve. Neurocognitive function was evaluated by the Stroop interference test (SIT) pre- and post-HIE. …”
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