Mitochondria transplanted adipose-derived stem cells/decellularized adipose tissue hydrogel for adipose tissue regeneration by Jiezhang Tang, Yige Han, Pan Ren, Lirong Xu, Zhanjun Lei, Jiaqi Li, Yiwei Cui, Jie Zhang, Jinqing Li, Xueyong Li

“…Nevertheless, the therapeutic potential is constrained by the suboptimal functionality of ADSCs, due to the donor health status, long-term culture, and the post-transplantation environment in vivo. …”
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Interruption of the visual cycle in a novel animal model induces progressive vision loss resembling Stargardts Disease by Fabiana Sassone, Catherine Estay-Ahumada, Michel J. Roux, Dominique Ciocca, Paola Rossolillo, Marie-Christine Birling, Janet R. Sparrow, Diego Montenegro, David Hicks

“…Post-mortem real-time PCR, immunohistochemistry and western blotting showed significant decrease of cone-specific (MW cone opsin) but not rod-specific (rhodopsin) markers. …”
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Parents’ experiences of family-based physical activity interventions: a systematic review and qualitative evidence synthesis by Carol Brennan, Evangeline Streight, Shishi Cheng, Ryan E. Rhodes

“…Conclusions This novel and comprehensive review offers practical recommendations to guide intervention development and inform future policy and practice such as: consider using co-design methods and social network analysis; promoting the benefits of PA on family functioning during recruitment; strengthening parents PA support identities; provide opportunities for social support for families post-intervention and educate coaches to create an environment of inclusivity and enjoyment. …”
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ISGylation and E3 ubiquitin ligases: an Atlantic salmon genetic perspective by Unni Grimholt, Hilde Sindre, Arvind Y. M. Sundaram, Arvind Y. M. Sundaram

“…Our results highlight the need for functional studies to clarify the roles of these candidates.…”
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Enhanced photocatalytic degradation of Rhodamine B using polyaniline-coated XTiO3(X = Co, Ni) nanocomposites by Mariyem Abouri, Abdellah Benzaouak, Mohamed Elouardi, Lahcen El Hamdaoui, Fatima Zaaboul, Khalil Azzaoui, Belkheir Hammouti, Rachid Sabbahi, Shehdeh Jodeh, Mohammed Alaoui El Belghiti, Adnane El Hamidi

“…X-ray diffraction (XRD) confirmed that the crystalline structures of CoTiO3 and NiTiO3 remained intact post-polymerization. At the same time, Fourier transform infrared spectroscopy (FTIR) verified the successful deposition of PANI through characteristic functional group vibrations. …”
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Identification of potential prognostic biomarkers of thymoma with myasthenia gravis based on serum proteomics by Xiaoting Lin, Xiaoting Lin, Xiaoting Lin, Xiaoting Lin, Peng Liu, Peng Liu, Peng Liu, Peng Liu, Guoyan Qi, Guoyan Qi, Guoyan Qi, Guoyan Qi

“…BackgroundThymoma is often associated with myasthenia gravis (MG), and the resection of thymoma improves myasthenic symptoms in patients with thymoma and MG (TMG), but some patients still have no relief. Through proteomic analysis, we examined preoperative serum samples from patients with TMG to identify key prognostic proteins that could serve as a foundation for clinically predicting postoperative efficacy and guiding treatment selection.MethodAccording to the Clinical Research Guidelines of the Myasthenia Gravis Foundation of America (MGFA) for Post-Intervention Status (PIS), 20 patients with TMG were divided into an effective group (T1) [the PIS was minimal manifestation status (MMS) and above] and an ineffective group (T2) (the PIS did not reach MMS and above), with 10 cases each, and a healthy control group (C) with nine cases. …”
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Dynamics of cerebral blood flow following sertraline treatment in adolescent depression by Wenyu Ren, Wenyu Ren, Xiao Liu, Zhiwei Zhang, Xiaoqin Zhang, Wei Wu, Xingyu Wang, Zhihui Yu, Chuan Liu, Renqiang Yu

“…Notably, the change in HAMD scores from pre- to post-treatment was positively correlated with baseline CBF in the left MFG, indicating the potential of this region as a prognostic indicator.…”
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Expression of Vascular Endothelial Growth Factor and Interleukin-6 in bile duct healing with autologous parietal peritoneum: a non-inferiority experimental study in rabbits by Anung Noto Nugroho, Soetrisno Soetrisno, Ambar Mudigdo, Kristanto Yuli Yarso, Dono Indarto, Akmal Zhahir Wahyudi

“…Statistical analysis was conducted with SPSS 28.0, using one-way analysis of variance (ANOVA) or Kruskal–Wallis tests, with significance set at p < 0.05. …”
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Identification and Mechanistic Studies of Key Genes in Thalamic Hemorrhage Pain by Multi-omics by Chen Yang, Ju Gao, Yaqun Li, Yinggang Xiao, Tianfeng Huang

“…Background: Thalamic hemorrhage pain (THP), a subtype of central post-stroke pain (CPSP), commonly develops following ischemic or hemorrhagic injury to the thalamus. …”
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Predicting community walking after stroke by Richard A. W. Felius, Richard A. W. Felius, Michiel Punt, Natasja C. Wouda, Natasja C. Wouda, Marieke Geerars, Sjoerd M. Bruijn, Jaap H. van Dieën

“…IntroductionA key element of personalized stroke rehabilitation is early prediction of an individual's potential to walk in the community.ObjectiveWe aim to determine the predictive value of patient characteristics, clinical test results, and Inertial Measurement Units (IMU) based balance, clinical gait and daily-life measures, measured at admission and discharge in clinical stroke rehabilitation, for community walking 6 months after stroke.MethodsData were collected from people after stroke during clinical rehabilitation and at 6 months post stroke. The assessment during rehabilitation consisted of an IMU-based 2-min walk test (2MWT), three IMU-based balance tests, an IMU-based measurement of gait in daily life, and several standard clinical tests, including the Berg Balance Scale, Barthel Index, Functional Ambulation Categories, Motricity Index (MI), and Trunk Control Test (TCT). …”
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Efficacy of Different Doses of Intra‐Articular Tranexamic Acid for Reducing Blood Loss and Lower Limb Swelling After Total Knee Arthroplasty: A Prospective, Randomized, Controlled... by Shuwei Ye, Yue Luo, Qianhao Li, Lijun Cai, Pengde Kang

“…One‐way analysis of variance (ANOVA), post hoc Bonferroni correction, Pearson chi‐square test and Fisher exact test were used for statistical analysis. …”
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Imaging observation of allogeneic bone and bone-induced calcium phosphate biomaterials as supplements in the treatment of infectious bone defects by Keye Li, Shan Yu, Daqiang Lin, Xu Zhang, Yuxiang Liang, Dong He, Qiang Guo, Junyu Tao, Yu Zhong, Zhigang Lang

“…Conclusion BAM-induced artificial bone demonstrated superior bone-forming efficacy compared to allogeneic grafts, exhibiting significantly lower resorption rates and reduced post-grafting cavitation. Furthermore, it achieved enhanced osseous quality, optimized weight-bearing zone reconstruction, and greater functional callus formation volume relative to allogeneic bone transplantation.…”
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The modern aspects of patients’ nutritional support during rehabilitation by A. V. Shvets, О. М. Ivanko, Yu. M. Deputat, O. V. Gorishna, O. V. Rychka

“…There is an increase in incidence rate of post-traumatic stress disorders among servicemen (veterans). …”
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Downregulation of forkhead box O1 (FOXO1) acetylation ameliorates cognitive dysfunction by inhibiting endoplasmic reticulum stress‐regulated neuronal apoptosis in APP/PS1 transgeni... by Nan Zhang, Zongyuan Zhao, Xiaoxiao Chen, Hanbing Yao, Min Zhu, Shuqing Ma, Hui Wang, Xianghong Yin, Ying Zhou, Chenfei Zheng, Jianmin Li, Jingye Pan, Kaicheng Wang, Bin Yang, Yunting Wang, Junming Fan, Yongsheng Gong, Rong Liu, Jing Zeng, Xiaofang Fan, Yangping Shentu

“…In addition, one‐way analysis of variance was conducted for behavioral assessments and other tests involving four distinct groups, followed by a Tukey's honestly significant difference test for post hoc pairwise comparisons. …”
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Rural spatial planning strengthens rural resilience and sustains development in China by Wenxin Wang, Yuzi Wang, Haohua Wang, Yan Liu, Qingyuan Yang

“…Drawing on resilience theory, this study proposes a conceptual framework for evaluating the effectiveness of RSP implementation, aiming to clarify the processes and underlying mechanisms through which planning enhances rural resilience (RS) capacity. Empirical analysis of representative case studies reveals that post-implementation villages exhibit improved overall development, including stabilized landscape order, enhanced regional functions, and greater adaptability among diverse stakeholders. …”
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Distinct trajectory patterns of neutrophil-to-albumin ratio predict clinical outcomes after endovascular therapy in large vessel occlusion stroke by Weiwei Gao, Junxuan Sun, Lingfeng Yu, Jingjing She, Yanan Zhao, Lijuan Cai, Xingyu Chen, Xingyu Chen, Renjing Zhu, Renjing Zhu, Renjing Zhu

“…The primary outcome was poor functional outcome at 90 days (modified Rankin Scale score 3–6). …”
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Injectable HAMA-CPC hydrogels loaded with high-yield 3D bioprinted adipose-derived stem cell small extracellular vesicles for increased bone repair by Wenbin Xu, Wenling Gao, Yi Zhang, Gang Hou, Wenhui Zhang, Jintao Deng, Kun Wang, Yichun Xu, Boxun Liu, Tao Xu, Chang Liu, Tangzhao Liang

“…In vivo, in a rat tibial defect model, this treatment strongly promoted bone regeneration, increasing the bone volume fraction (BV/TV), bone volume (BV), and trabecular thickness (Tb.Th) at 4 weeks post-surgery. Mechanistically, proteomic analysis revealed that NAMPT in 3D-sEVs upregulated S1PR1 in HUVECs, leading to increased VEGF expression and angiogenesis. …”
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Co-pyrolyzed and valorized municipal solid wastes and coconut husks into biochar adsorbing methylene blue in aqueous solution by Divine Angela G. Sumalinog, Dennis C. Ong, Jose Antonio I. Pimentel, Ralf Ruffel M. Abarca, Carl Francis Z. Lacson, Nurak Grisdanurak, Sergio C. Capareda, Mark Daniel G. de Luna

“…Furthermore, the adsorption behaviors suggested that the phenomena were (1) potentially influenced by chemisorption from kinetic studies, (2) best fitted the Freundlich isotherm model, denoting a heterogeneous adsorption mechanism, and (3) endothermic and spontaneous from the thermodynamic analysis. The proposed adsorption mechanism was feasibly dominated by physisorption, as indicated by low ΔG° values (−1.234 kJ mol⁻¹ to −4.531 kJ mol⁻¹) and functional groups, likely facilitating hydrogen bonding, which perhaps followed by initially identified chemisorption from kinetic studies. …”
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Sleeping sound with autism spectrum disorder (ASD): study protocol for an efficacy randomised controlled trial of a tailored brief behavioural sleep intervention for ASD by Harriet Hiscock, Cathrine Mihalopoulos, Nicole Papadopoulos, Emma Sciberras, Jane McGillivray, Lidia Engel, Matthew Fuller-Tyszkiewicz, Susannah T Bellows, Deborah Marks, Patricia Howlin, Nicole Rinehart

“…Intervention impact on child and family functioning is also assessed.Methods and analysis The RCT aims to recruit 234 children with a diagnosis of ASD, aged 5–13 years, who experience moderate to severe sleep problems. …”
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The Efficiency of <i>Chlorella vulgaris</i> in Heavy Metal Removal: A Comparative Study of Mono- and Multi-Component Metal Systems by Eleni Kyratzopoulou, Nikoletta Kyzaki, Lamprini Malletzidou, Evangelos Nerantzis, Nikolaos A. Kazakis

“…Experiments were performed in controlled laboratory conditions, and metal removal analysis was performed through atomic absorption spectroscopy (AAS). …”
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